EXHIBIT 32.1

                      STATEMENT OF CHIEF EXECUTIVE OFFICER
         PURSUANT TO SECTION 1350 OF TITLE 18 OF THE UNITED STATES CODE

      Pursuant to Section 1350 of Title 18 of the United States Code, I, Richard
J. DePiano, the Chairman and Chief Executive Officer of Escalon Medical Corp.
(the "Company"), hereby certify that, to the best of my knowledge:

      1.    The Company's Form 10-Q Quarterly Report for the period ended
            December 31, 2004 (the "Report") fully complies with the
            requirements of Section 13(a) of the Securities Act of 1934; and

      2.    The information contained in this quarterly report fairly presents,
            in all material respects, the financial condition and results of
            operations of the Company.

Date: February 14, 2005                     /s/ Richard J. DePiano
                                            ------------------------------------
                                            Richard J. DePiano
                                            Chairman and Chief Executive Officer

      A signed copy of this written statement required by Section 906 of the
Sarbanes-Oxley Act of 2002 has been provided to Escalon Medical Corp. and will
be retained by Escalon Medical Corp. and furnished to the Securities and
Exchange Commission or its staff upon request.