EXHIBIT 32.1

                STATEMENT OF CHAIRMAN AND CHIEF EXECUTIVE OFFICER
         PURSUANT TO SECTION 1350 OF TITLE 18 OF THE UNITED STATES CODE

      Pursuant to Section 1350 of Title 18 of the United States Code, I, Richard
J. DePiano, the Chairman and Chief Executive Officer of Escalon Medical Corp.
(the "Registrant"), hereby certify that, to the best of my knowledge:

      1.    The Company's Form 10-Q Quarterly Report for the period ended March
            31, 2005 fully complies with the requirements of Section 13(a) of
            the Exchange Act; and

      2.    The information contained in this report fairly presents, in all
            material respects, the financial condition and results of operations
            of the Registrant.

Date:    May 16, 2005                    /s/  Richard J. DePiano
                                         -----------------------
                                         Richard J. DePiano
                                         Chairman and Chief Executive Officer

      A signed copy of this written statement required by Section 906 of the
Sarbanes-Oxley Act of 2002 has been provided to the Registrant and will be
furnished to the Securities Exchange Commission or its staff upon request.


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