EXHIBIT 99.1

FACTORS AFFECTING OUR FUTURE OPERATING RESULTS

 WE HAVE SUBSTANTIAL DEBT AND WE MAY INCUR  SUBSTANTIALLY  MORE DEBT, WHICH
COULD  AFFECT OUR ABILITY TO MEET OUR DEBT  OBLIGATIONS  AND MAY  OTHERWISE
RESTRICT OUR ACTIVITIES.

     We have  substantial  debt,  and we may be able to  incur  substantial
additional  debt in the  future.  As of  December  31,  2003,  we had total
indebtedness of approximately $196.4 million, net of cash of $45.1 million.
We are  also  permitted  by the  terms  of our  debt  instruments  to incur
substantial additional indebtedness, subject to the restrictions therein.

     Our debt could have  important  consequences  to you. For example,  it
could:

     o    make it more  difficult for us to satisfy our  obligations  under
          our debt instruments;

     o    require us to dedicate a substantial  portion of our cash flow to
          payments on our  indebtedness,  which would  reduce the amount of
          cash   flow   available   to  fund   working   capital,   capital
          expenditures,    product    development   and   other   corporate
          requirements;

     o    increase  our  vulnerability  to  general  adverse  economic  and
          industry conditions, including changes in raw material costs;

     o    limit our ability to respond to business opportunities;

     o    limit  our  ability  to  borrow  additional  funds,  which may be
          necessary; and

     o    subject us to financial and other restrictive  covenants,  which,
          if we fail to comply with these  covenants and our failure is not
          waived or cured,  could  result in an event of default  under our
          debt.

TO SERVICE OUR DEBT,  WE WILL  REQUIRE A  SIGNIFICANT  AMOUNT OF CASH.  OUR
ABILITY TO GENERATE CASH DEPENDS ON MANY FACTORS BEYOND OUR CONTROL.

     Our ability to make  payments on our debt and to fund planned  capital
expenditures  and  research  and  development  efforts  will  depend on our
ability to generate cash in the future.  This, to an extent,  is subject to
general economic, financial, competitive, legislative, regulatory and other
factors,  including  those  described in this exhibit,  that are beyond our
control.

     We cannot assure you that our business will generate  sufficient  cash
flow from  operations  or that future  borrowings  will be  available to us
under our new senior credit  facility in an amount  sufficient to enable us
to pay our  debt,  or to fund our  other  liquidity  needs.  We may need to
refinance all or a portion of our  indebtedness on or before  maturity.  We
cannot  assure  you  that we will be  able to  refinance  any of our  debt,
including our senior credit  facility and the senior notes, on commercially
reasonable terms or at all.

THE AGREEMENTS GOVERNING OUR DEBT IMPOSE RESTRICTIONS ON OUR BUSINESS.

     The indenture governing our senior notes and the agreements  governing
our  senior  credit  facility  contain  a  number  of  covenants   imposing
significant restrictions on our business. These restrictions may affect our
ability to operate our business and may limit our ability to take advantage
of potential  business  opportunities as they arise. The restrictions these
covenants place on us and our restricted  subsidiaries  include limitations
on our ability and the ability of our restricted subsidiaries to:

     o    enter into sale and leaseback arrangements;

     o    incur liens; and

     o    consolidate, merge, sell or lease all or substantially all of our
          assets;

     Our senior credit facility also requires us to meet several  financial
ratios.

     Our ability to comply with these  agreements may be affected by events
beyond our control,  including prevailing economic,  financial and industry
conditions and are subject to the risks in this exhibit.  The breach of any
of these  covenants or  restrictions  could  result in a default  under the
indenture  governing the senior notes or under our senior credit  facility.
An event of  default  under our senior  credit  facility  would  permit our
lenders to declare all amounts borrowed from them to be immediately due and
payable.  Acceleration of our other  indebtedness may cause us to be unable
to make  interest  payments  on the  senior  notes and repay the  principal
amount of the senior notes.

CURRENCY FLUCTUATIONS MAY AFFECT OUR OPERATING PROFITS.

     Because we conduct operations in many countries,  our operating income
can be significantly  affected by fluctuations in currency  exchange rates.
Swiss franc-denominated expenses represent a much greater percentage of our
operating expenses than Swiss  franc-denominated sales represent of our net
sales.  In  part,  this is  because  most  of our  manufacturing  costs  in
Switzerland relate to products that are sold outside Switzerland. Moreover,
a substantial  percentage  of our research and  development  expenses,  and
general and administrative expenses are incurred in Switzerland. Therefore,
if the Swiss franc  strengthens  against  all or most of our major  trading
currencies  (e.g.,  the  U.S.  dollar,   the  euro,  other  major  European
currencies and the Japanese yen), our operating profit is reduced.  We also
have significantly more sales in European  currencies (other than the Swiss
franc) than we have expenses in those currencies.  Therefore, when European
currencies  weaken  against the U.S.  dollar and the Swiss  franc,  it also
decreases our operating profits. Accordingly, the Swiss franc exchange rate
to the  euro  is an  important  cross-rate  monitored  by the  Company.  We
estimate  that a one percent  strengthening  of the Swiss franc against the
euro would result in a decrease in our earnings  before tax of $0.8 million
to $1.2 million on an annual basis.  In addition to the effects of exchange
rate movements on operating  profits,  our debt levels can fluctuate due to
changes in exchange  rates,  particularly  between the U.S.  dollar and the
Swiss  franc.  Based on our  outstanding  debt at  December  31,  2003,  we
estimate  that a ten  percent  weakening  of the U.S.  dollar  against  the
currencies in which our debt is denominated, would result in an increase of
approximately $4.7 million in the reported U.S. dollar value of the debt.

WE  ARE  SUBJECT  TO  CERTAIN  RISKS  ASSOCIATED  WITH  OUR   INTERNATIONAL
OPERATIONS AND FLUCTUATING CONDITIONS IN EMERGING MARKETS.

     We conduct business in many countries,  including  emerging markets in
Asia,  Latin America and Eastern Europe.  In addition to the currency risks
discussed above,  international operations pose other substantial risks and
problems for us. For  instance,  various  local  jurisdictions  in which we
operate  may  revise  or  alter  their   respective  legal  and  regulatory
requirements.  In addition,  we may  encounter one or more of the following
obstacles or risks:

     o    tariffs and trade barriers;

     o    difficulties in staffing and managing local operations;

     o    credit risks  arising from  financial  difficulties  facing local
          customers and distributors;

     o    difficulties in protecting intellectual property;

     o    nationalization of private enterprises;

     o    restrictions on investments and/or limitations  regarding foreign
          ownership;

     o    adverse tax  consequences,  including  imposition  or increase of
          withholding  and other taxes on remittances and other payments by
          subsidiaries; and

     o    uncertain  local  economic,   political  and  social  conditions,
          including hyper-inflationary conditions.

     We must  also  comply  with a variety  of  regulations  regarding  the
conversion  and  repatriation  of funds  earned  in local  currencies.  For
example,  converting  earnings  from our  operations  in China  into  other
currencies and repatriating these funds require governmental  approvals. If
we cannot comply with these or other  applicable  regulations,  we may face
increased difficulties in utilizing cash flow generated by these operations
outside of China.

     Economic  conditions  in  emerging  markets  have  from  time  to time
deteriorated  significantly,  and some  emerging  markets are  experiencing
recessionary trends,  severe currency devaluations and inflationary prices.
Moreover,  economic  problems  in  individual  markets  can spread to other
economies, adding to the adverse conditions we face in emerging markets. We
remain  committed to emerging  markets,  particularly  those in Asia, Latin
America and Eastern Europe.  However,  we expect the  fluctuating  economic
conditions  will affect our results of  operations in these markets for the
foreseeable future.

     The past outbreak and possible  recurrence of severe acute respiratory
syndrome, or SARS, or other public health-related developments could have a
negative impact on our results of operations.  In particular,  SARS-related
factors  may  reduce  our  sales  to  affected   regions  and  disrupt  our
manufacturing centers located in China. Any disruption to our manufacturing
operations could result in reduced sales and increased supply chain costs.

WE  OPERATE  IN HIGHLY  COMPETITIVE  MARKETS,  AND IT MAY BE  DIFFICULT  TO
PRESERVE OPERATING MARGINS,  GAIN MARKET SHARE AND MAINTAIN A TECHNOLOGICAL
ADVANTAGE.

     Our  markets  are  highly   competitive.   Weighing   and   analytical
instruments   markets  are  also  fragmented  both  geographically  and  by
application,  particularly the industrial and food retailing markets.  As a
result, we face numerous regional or specialized competitors,  many of whom
are well established in their markets. In addition, some of our competitors
are divisions of larger  companies with potentially  greater  financial and
other resources than our company.  Taken together,  the competitive  forces
present in our markets can impair our operating  margins in certain product
lines and  geographic  markets.  We expect our  competitors  to continue to
improve the design and  performance  of their products and to introduce new
products with competitive prices.  Although we believe that we have certain
technological and other advantages over our competitors, we may not be able
to realize and maintain these advantages.

OUR  PRODUCT  DEVELOPMENT  EFFORTS  MAY  NOT  PRODUCE  COMMERCIALLY  VIABLE
PRODUCTS IN A TIMELY MANNER.

     We must introduce new products and enhancements in a timely manner, or
our products could become  technologically  obsolete over time, which would
harm our operating results. To remain competitive, we must continue to make
significant  investments in research and  development,  sales and marketing
and  customer  service  and  support.  We  cannot be sure that we will have
sufficient  resources to continue to make these investments.  In developing
new products, we may be required to make substantial  investments before we
can  determine  their  commercial  viability.  As a  result,  we may not be
successful in developing new products and we may never realize the benefits
of our research and development activities.

A PROLONGED  DOWNTURN OR ADDITIONAL  CONSOLIDATION  IN THE  PHARMACEUTICAL,
FOOD, FOOD RETAILING AND CHEMICALS  INDUSTRIES  COULD ADVERSELY  AFFECT OUR
OPERATING RESULTS.

     Our  products are used  extensively  in the  pharmaceutical,  food and
beverage and chemical  industries.  Consolidation in the pharmaceutical and
chemicals industries hurt our sales in prior years. A prolonged downturn or
additional  consolidation in any of these industries could adversely affect
our operating  results.  In addition,  the capital spending policies of our
customers in these  industries  are based on a variety of factors we cannot
control,  including the resources available for purchasing  equipment,  the
spending priorities among various types of equipment and policies regarding
capital expenditures  generally.  Any decrease or delay in capital spending
by our  customers  would  cause our  revenues to decline and could harm our
profitability.

WE MAY FACE RISKS ASSOCIATED WITH FUTURE ACQUISITIONS.

     We  plan  to  pursue  acquisitions  of  complementary  product  lines,
technologies or businesses. Acquisitions involve numerous risks, including:

     o    difficulties  in the  assimilation  of the  acquired  operations,
          technologies and products;

     o    diversion of management's attention from other business concerns;
          and

     o    potential departures of key employees of the acquired company.

     If we successfully  identify  acquisitions  in the future,  completing
such acquisitions may result in:

     o    new  issuances  of our  stock  that may be  dilutive  to  current
          owners;

     o    increases in our debt and contingent liabilities; and

     o    additional amortization expenses related to intangible assets.

     Any of these  acquisition-related  risks  could  materially  adversely
affect our profitability.

     We may not be able to  identify,  successfully  complete or  integrate
potential  acquisitions  in the future.  However,  even if we can do so, we
cannot be sure that these  acquisitions  will have a positive impact on our
business or operating results.

IF WE CANNOT PROTECT OUR INTELLECTUAL PROPERTY RIGHTS, OR IF WE INFRINGE OR
MISAPPROPRIATE  THE  PROPRIETARY  RIGHTS OF OTHERS,  OUR OPERATING  RESULTS
COULD BE HARMED.

     Our success  depends on our  ability to obtain and enforce  patents on
our  technology  and to protect  our trade  secrets.  Our  patents  may not
provide complete  protection,  and competitors may develop similar products
that are not covered by our patents.  Our patents may also be challenged by
third  parties and  invalidated  or narrowed.  Although we take measures to
protect confidential  information,  improper use or disclosure of our trade
secrets may still occur.

     We may be sued for infringing on the  intellectual  property rights of
others.   The  cost  of  any  litigation  could  affect  our  profitability
regardless of the outcome, and management  attention could be diverted.  If
we are  unsuccessful in such litigation,  we may have to pay damages,  stop
the  infringing  activity  and/or obtain a license.  If we fail to obtain a
required  license,  we may be unable to sell  some of our  products,  which
could result in a decline in our revenues.

DEPARTURES OF KEY EMPLOYEES COULD IMPAIR OUR OPERATIONS.

     We have  employment  contracts  with  each of our  key  employees.  In
addition, our key employees own shares of our common stock and have options
to purchase additional shares.  Nevertheless,  such individuals could leave
the Company.  If any key employees  stopped  working for us, our operations
could be harmed. We have no key man life insurance policies with respect to
any of our senior executives.

WE MAY BE ADVERSELY AFFECTED BY ENVIRONMENTAL LAWS AND REGULATIONS.

     We  are  subject  to  various   environmental  laws  and  regulations,
including those relating to:

     o    air emissions;

     o    wastewater discharges;

     o    the handling and disposal of solid and hazardous wastes; and

     o    the  remediation  of  contamination  associated  with the use and
          disposal of hazardous substances.

     We  incur  capital  and  operating   expenditures  in  complying  with
environmental  laws and  regulations  both in the U.S.  and abroad.  We are
currently  involved in, or have  potential  liability  with respect to, the
remediation  of past  contamination  in  facilities  both in the  U.S.  and
abroad. In addition, some of these facilities have or had been in operation
for many decades and may have used  substances or generated and disposed of
wastes that are  hazardous  or may be  considered  hazardous in the future.
These sites and  disposal  sites owned by others to which we sent waste may
in the  future be  identified  as  contaminated  and  require  remediation.
Accordingly,  it is possible  that we could  become  subject to  additional
environmental  liabilities  in the  future  that may harm  our  results  of
operations or financial condition.

WE MAY BE  ADVERSELY  AFFECTED  BY FAILURE TO COMPLY  WITH  REGULATIONS  OF
GOVERNMENTAL AGENCIES.

     Our products are subject to regulation by governmental agencies. These
regulations  govern a wide variety of activities  relating to our products,
from design and development, to labeling,  manufacturing,  promotion, sales
and distribution.  If we fail to comply with these regulations, we may have
to recall  products  and  cease  their  manufacture  and  distribution.  In
addition, we could be subject to fines or criminal prosecution.

GUIDELINES   RELATING   TO   ACCOUNTING   FOR   GOODWILL   COULD  MAKE  OUR
ACQUISITION-RELATED CHARGES LESS PREDICTABLE IN ANY GIVEN REPORTING PERIOD.

     Starting in 2002, our goodwill amortization charges have ceased. As at
December  31, 2003 our  consolidated  balance  sheet  included  goodwill of
$421.9 million and other intangible assets of $126.9 million.

     Our  business  acquisitions  typically  result in  goodwill  and other
intangible  assets,  which affect the amount of future period  amortization
expense  and  possible   impairment   expense  that  we  will  incur.   The
determination of the value of such intangible assets requires management to
make  estimates  and  assumptions  that affect our  consolidated  financial
statements.

     In  accordance  with SFAS No.  142,  "Goodwill  and  Other  Intangible
Assets" ("SFAS 142"), our goodwill and  indefinite-lived  intangible assets
are not amortized,  but are evaluated for impairment annually in the fourth
quarter, or more frequently if events or changes in circumstances  indicate
that an  asset  might  be  impaired.  The  annual  evaluation  is  based on
valuation  models that  estimate  fair value based on expected  future cash
flows and profitability  projections.  In preparing the valuation models we
consider a number of factors,  including operating results, business plans,
economic  conditions,  future cash flows, and transactions and market place
data.  There are inherent  uncertainties  related to these  factors and our
judgment in  applying  them to the  impairment  analyses.  The  significant
estimates  and  assumptions  within our fair  value  models  include  sales
growth, controllable cost growth, perpetual growth, effective tax rates and
discount rates.  Our assessments to date have indicated that there has been
no impairment of these assets.

     Our drug discovery reporting unit is sensitive to changes in Biopharma
capital spending and, drug discovery  experienced a double-digit decline in
revenue  and  profitability  during  2003.  However,  the fair value of the
Company's drug discovery  reporting unit exceeded its carrying value of $29
million as of September 30, 2003 and December 31, 2003. In accordance  with
the provisions of SFAS 142, the Company will monitor the fair value of this
reporting  unit  closely to determine  if the 2004  business  plan is being
achieved.  For example,  we will monitor whether the forecasted benefits of
our drug discovery cost reduction  programs are being  realized,  including
the program of manufacturing site rationalization currently in progress.

     Should  any  of  these  estimates  or  assumptions  in  the  preceding
paragraphs  not be  accurate,  or  should  we  incur  lower  than  expected
operating  performance or cash flows, we may experience a triggering  event
that requires a new fair value  assessment for our reporting units prior to
the  required  annual  assessment.  These  types of  events  and  resulting
analysis  could  result  in  impairment  charges  for  goodwill  and  other
indefinite  lived  intangible  assets if the fair value  estimate  declines
below the carrying value.

     Our  amortization  expense  related to  intangible  assets with finite
lives may  materially  change  should our  estimates  of their useful lives
change.

IF WE ARE REQUIRED TO ACCOUNT FOR EMPLOYEES' OPTIONS UNDER OUR STOCK OPTION
PLAN AS A COMPENSATION EXPENSE, IT WOULD REDUCE OUR NET EARNINGS.

     There has been  increasing  public  debate in the U.S.  and  elsewhere
about the proper accounting treatment for employee stock options.  Although
we are not  currently  required  to  record  any  compensation  expense  in
connection  with option grants that have an exercise price at or above fair
market value,  it is possible that future laws or regulations  will require
us to treat all stock  options as a  compensation  expense.  Note 12 to our
financial  statements  shows the  impact  that such a change in  accounting
treatment  would have had on our net  earnings and earnings per share if it
had  been  in  effect  during  the  past  three  fiscal  years  and  if the
compensation expense were calculated as described in Note 12.

UNANTICIPATED CHANGES IN OUR TAX RATES OR EXPOSURE TO ADDITIONAL INCOME TAX
LIABILITIES COULD IMPACT OUR PROFITABILITY.

     We are subject to income  taxes in both the United  States and various
other  foreign  jurisdictions,  and  our  domestic  and  international  tax
liabilities   are  subject  to  allocation  of  expenses  among   different
jurisdictions. Our effective tax rates could be adversely affected by:

     o    changes in the mix of earnings by jurisdiction

     o    changes in tax laws or tax rates

     o    changes in the valuation of deferred tax assets and liabilities

     o    material audit adjustments.

     In particular,  the carrying  value of deferred tax assets,  which are
predominantly in the U.S., is dependent upon our ability to generate future
taxable  income in the U.S. In addition,  the amount of income taxes we pay
is  subject  to  ongoing  audits in  various  jurisdictions  and a material
assessment by a governing tax authority could affect our profitability.