EXHIBIT 32.1

                            CERTIFICATION PURSUANT TO
                               18 U.S.C. SS.1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002


In connection with the Annual Report of Vascular Solutions, Inc. (the "Company")
on Form 10-K for the period ended December 31, 2004, as filed with the
Securities and Exchange Commission (the "Report"), I, Howard Root, Chief
Executive Officer of the Company, certify, pursuant to 18 U.S.C. ss.1350, as
adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that, to the
best of my knowledge:

         1.       The Report fully complies with the requirements of Section
                  13(a) or 15(d) of the Securities Exchange Act of 1934; and

         2.       The information contained in the Report fairly presents, in
                  all material respects, the financial condition and results of
                  operations of the Company.


                                                /s/ Howard Root
                                                --------------------------------
                                                Howard Root
                                                Chief Executive Officer
                                                February 4, 2005