EXHIBIT 24 POWER OF ATTORNEY KNOW ALL PERSONS BY THESE PRESENT, that each person whose signature appears below hereby constitutes and appoints John Howell Bullion , his true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution for him and in his name, place and stead, in any and all capacities, to sign the Annual Report on Form 10-K of Orphan Medical, Inc. for the twelve months ended December 31, 1996, and all amendments to such Annual Report on Form 10-K and to file same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite or necessary to be done in and about the premises, as fully to all intents and purposes he might or could do in person, hereby ratifying and confirming all said attorneys-in-fact and agents or any of them, or their or his substitutes, may lawfully do or cause to be done by virtue hereof. Signature Date /s/ John Howell Bullion February 27, 1997 John Howell Bullion Chief Executive Officer & Secretary (Principal Executive Officer) and Director /s/ William B. Adams February 27, 1997 William B. Adams Chairman of the Board and Director /s/ Bertram A. Spilker February 27, 1997 Bertram A. Spilker President and Director /s/ Maurice R. Taylor, III February 27, 1997 Maurice R. Taylor, II Director /s/ W. Leigh Thompson February 27, 1997 W. Leigh Thompson Director /s/ William M. Wardell February 27, 1997 William M. Wardell Director /s/ Lawrence C. Weaver February 27, 1997 Lawrence C. Weaver Director