EXHIBIT 99 OBLIGATIONS OF ZENECA PLC REGARDING PUT Section 1.10 of the Merger Agreement requires Zeneca to, or to cause one or more of its affiliates to, pay to the Company immediately prior to the time that such amounts become due and payable all amounts, if any, that, assuming that such payments could be made without violating Section 160 of the Delaware Law, any bankruptcy or insolvency law or other law or regulation for the protection of creditors, will be due and payable to the holders of the Special Common Stock pursuant to the Put feature of the Special Common Stock. In exchange for such payment, the Company will issue to Zeneca (or to its designated affiliates) a number of shares of Common Stock equal to the number of shares of the Special Common Stock acquired thereby by the Company. Section 160 of the Delaware Law provides that a Delaware corporation may not purchase any shares of its capital stock when the capital of the corporation is impaired or when such purchase would cause any impairment of the capital of the corporation. The maximum amount Zeneca is obligated to pay to the Company is the product of the Put Price multiplied by the total number of shares of the Special Common Stock with respect to which the Put is exercised. If the Company consummates the purchase of the Special Common Stock in contravention of Section 160 of the Delaware Law or any other law for the protection of creditors, Zeneca will indemnify and hold harmless the directors of the Company against any liabilities arising out of such purchase. If Zeneca or the Company determines that the Company may be unable to consummate the purchase of all of the Special Common Stock at the Put Price per share in accordance with the Certificate of Incorporation or the Company is unable to pay the Put Price with respect to all such shares in accordance with the Certificate of Incorporation, in either case, without violating Section 160 of the Delaware Law, any bankruptcy or insolvency law or other law or regulation for the protection of creditors, then the obligation of Zeneca to pay, or cause one or more of its affiliates to pay, the amounts set forth above will terminate. In lieu thereof, Zeneca will (or will cause one of its affiliates to) purchase, and make all arrangements necessary to purchase, during the Put Period, directly from the holders of the Special Common Stock at the Put Price, the Special Common Stock which such holders elect or have elected to require the Company to purchase. As permitted under the Merger Agreement, Zeneca has assigned to Zeneca PLC all of the obligations of Zeneca to purchase Special Common Stock described in the preceding sentence. The holders of the Special Common Stock will have the right to enforce against Zeneca PLC the obligation of Zeneca (or its affiliates) to pay the amounts set forth above. 39 DESCRIPTION OF THE SPECIAL COMMON STOCK In the Merger, each outstanding Share will be converted into the right to receive $18.875 in cash and, although no fractional shares will be issued, one- half share of Special Common Stock. Pursuant to the Merger Agreement and effective upon consummation of the Merger, the Company's certificate of incorporation will be amended by operation of the Merger to, among other things, authorize the issuance of the Special Common Stock and establish the terms thereof. Under Article FOURTH of the Certificate of Incorporation ("Article 45 Fourth"), effective upon the Merger, the preferences, rights and qualifications, limitations, and restrictions of the Special Common Stock and the Common Stock will be identical in all respects, except as specifically set forth in Article Fourth and except for the right of each class to elect five directors as provided in Article FIFTH of the Certificate of Incorporation. Set forth below is a description of the terms of the Special Common Stock, including the differences between such terms and the terms of the Common Stock as set forth in Article Fourth. The following description of the terms of the Special Common Stock does not purport to be complete and is qualified in its entirety by reference to the text of the Certificate of Incorporation which is attached to this Proxy Statement as Annex B and is incorporated herein by reference. AUTHORIZED SHARES The Company's certificate of incorporation currently provides for authorized capital of 30,000,000 shares, consisting of 25,000,000 shares of Common Stock, $.001 par value per share, and 5,000,000 shares of Preferred Stock, $.001 par value per share. By operation of the Merger, Article Fourth of the Certificate of Incorporation will provide for authorized capital of 27,500,000 shares, of which 15,000,000 shares will be designated Common Stock, 7,500,000 shares will be designated Callable Puttable Common Stock and 5,000,000 shares will be designated Preferred Stock, each with a par value of $.001 per share. There are no shares of the Preferred Stock presently issued or outstanding and there will not be any shares thereof issued or outstanding immediately following the Merger. CALL AND PUT FEATURES OF THE SPECIAL COMMON STOCK The Company has no right to redeem the Common Stock. The Company will not have the right to call or redeem any shares of the Special Common Stock and will not purchase or otherwise acquire for value any outstanding shares of the Special Common Stock, except as provided in the Certificate of Incorporation. Call. The Company will have the option (the "Call") to purchase, subject to having available funds therefor as described herein, effective as of a date (the "Call Date") fixed by the Company within a period commencing with the Effective Time and ending on the close of business on the last day of the forty-eighth month thereafter (the "Call Period"), at the applicable price per share (the "Call Price"), all, but not less than all, of the outstanding shares of Special Common Stock by (1) giving written notice of the exercise of the Call (the "Call Notice") in accordance with the terms of the Certificate of Incorporation at any time during the Call Period and (2) making the deposit described below with a bank or trust company meeting certain criteria (the "Depositary"), prior to the Call Date, with irrevocable instructions to the Depositary to pay the Call Price for all shares of Special Common Stock surrendered. The Call Notice will set forth, among other things, the Call Date and instructions as to how to obtain the Call Price for the Special Common Stock and will be accompanied by a letter of transmittal for use by a holder of Special Common Stock in surrendering certificates for the Special Common Stock and obtaining the Call Price therefor. The Call may only be exercised by the Company upon the affirmative vote (or written consent) of a majority of the holders of the shares of Common Stock, voting separately as a class; provided, however, that, regardless of such vote, the Company will only exercise the Call if the purchase of all of the shares of Special Common Stock pursuant to the exercise of the Call would not be in violation of Section 160 of the Delaware Law or any other law for the protection of creditors. The Call Price is the market price of the Special Common Stock, subject, during the first two years and seven months after the Effective Time, to a minimum and maximum price therefor. The maximum price per share is $50.00. The minimum price is $42.00 per share, discounted from the date which is two and one-half years from the Effective Time at a rate which, when compounded on a daily basis, is equal to four percent on an annualized basis if the Call is made before two and one-half years from the Effective Time. By way of illustration, assuming that the Company calls the Special Common Stock on the date which is (a) 183 days after the Effective Time, the minimum Call Price would be $38.77 per share, (b) 365 days after the Effective Time, the minimum Call Price would be $39.55 per share, (c) 548 days (or approximately one and one-half years) after the Effective Time, the minimum Call Price would be $40.35 per share and (d) 730 days (or two years) after the Effective Time, the minimum Call Price would be $41.17 per share. 46 At least ten and no more than fifteen days prior to the Call Date (which period may be extended if required under the Exchange Act or the regulations promulgated thereunder), the Company will mail the Call Notice to each holder of Special Common Stock at such holder's address as it appears on the transfer books of the Company and to each holder of a Replacement Option at the address for such holder set forth in the records of the Company. On the date of mailing of the Call Notice, the Company will give a similar notice by publication in a newspaper of general circulation in Los Angeles, California. Put. Unless the Call has been previously exercised, during a period commencing with the date which is the earlier of thirty calendar months from the Effective Time or the date upon which there is a change in control (defined as a transfer or other disposition of shares by Zeneca PLC or its affiliates or the issuance of additional shares, the result of which is that Zeneca PLC or its affiliates no longer own, directly or indirectly, more than fifty percent of the outstanding shares of Common Stock or voting equity securities of the Company) and ending on the close of business on the twentieth business day after the date which is thirty calendar months from the Effective Time (or such later date as may be required under the Exchange Act and the rules and regulations promulgated thereunder) (the "Put Period"), each holder of the Special Common Stock shall have the option (the "Put") to require the Company to purchase all or a part of the shares of the Special Common Stock held by such holder at a purchase price of $42.00 per share (the "Put Price"), subject to having funds legally available therefor as described herein. If such funds are not legally available to the Company as set forth in the Merger Agreement, Zeneca PLC will assume the obligations of the Company with respect to the Put. See "THE MERGER AGREEMENT--Obligations of Zeneca PLC Regarding Put." Holders who desire to exercise their Put must deliver written notice thereof (the "Put Notice") during the Put Period to the Company or the Depositary electing to have shares of Special Common Stock purchased by the Company and specifying therein the whole number of shares of Special Common Stock which such holder has elected to cause the Company to purchase, together with a certificate or certificates representing such shares. At least ten and not more than thirty days prior to the beginning of the Put Period, the Company will mail a written notice (the "Put Notification") to each holder of Special Common Stock at such holder's address as it appears on the transfer books of the Company and to each holder of an option to purchase shares of the Special Common Stock at the address for such holder set forth in the records of the Company informing each such holder of his, her or its right to exercise the Put, the date of the commencement and termination of the Put Period, the Put Price, the identity and address of the Depositary and instructions as to how to exercise their Put. A notice similar to the Put Notification will be given by the Company by publication in a newspaper of general circulation in Los Angeles, California at least ten and not more than thirty days prior to the beginning of the Put Period. If the Company fails to give the Put Notification to the holders of Special Common Stock at least ten days prior to the beginning of the Put Period as provided herein, the rights of the holders of the Special Common Stock will not be prejudiced thereby and the Put will nevertheless become exercisable at the beginning of the Put Period as herein provided but the expiration of the Put Period will be extended to that date which is twenty-five business days from the date the Put Notification is given to holders of the Special Common Stock. Surrender and Payment. Prior to the date the Company gives the Put Notification (or prior to the beginning of the Put Period, if the Company does not timely give the Put Notification) or the Call Notice, as the case may be, the Company will appoint the Depositary. Prior to the Call Date, the Company will deposit with the Depositary an amount of cash sufficient to pay in full the Company's obligations pursuant to the Call, assuming for purposes thereof that all outstanding shares of Special Common Stock are to be purchased pursuant to the Call. In the case of the exercise of the Call, each holder of shares of Special Common Stock and, in the case of the exercise of the Put, each holder who has exercised the Put, will be paid, within two business days following the surrender of the certificate or certificates representing such shares to the Depositary or the Company together with a properly executed letter of transmittal, in the case of the exercise of the Call, or the Put Notice, in the case of the exercise of the Put, covering such shares of stock, the Call Price or the Put Price for such shares, as the case may be. In no event, however, will the Call Price be payable prior to the Call Date. As certificates representing shares of Special Common Stock with respect to which the Put has been properly exercised are surrendered to the Depositary or the Company, the Company will 47 immediately deposit with the Depositary cash necessary to pay in full the Put Price for such shares. Upon such payment, each surrendered certificate so paid for will be transferred to the Company, canceled and retired. In the event of the exercise of the Put for less than all of the shares of Special Common Stock represented by a certificate, a new certificate representing the shares of Special Common Stock not purchased pursuant to the exercise of the Put will be issued to the holder of such shares. Following the Put Period, any monies deposited by the Company with the Depositary for purchases of shares upon exercise of the Put which are not required to be used for the purchase of shares of Special Common Stock pursuant to the exercise of the Put will revert to the general funds of the Company. Any monies deposited with the Depositary for purchase of shares pursuant to the exercise of the Call and unclaimed at the end of two years from that date which is twenty-one business days following the Call Date will revert to the general funds of the Company. After such reversion of funds, any holder of shares of Special Common Stock may look only to the Company for the payment of the Call Price. If the Call Notice is given and funds are deposited (together with irrevocable instructions to the Depositary to pay the Call Price) as set forth in the Certificate of Incorporation, from and after the Call Date, all of the shares of Special Common Stock, other than the shares issued upon the exercise of certain Replacement Options (as described below), will no longer be deemed outstanding and all rights of the holders of such shares will cease and terminate. If the Call Date occurs prior to the date which is fourteen months from the Closing (the "Option Share Termination Date") and the Company has complied with all of the requirements with respect to the exercise of the Call, the holders of shares of Special Common Stock acquired within two months after the Effective Time upon the exercise of Replacement Options which are incentive stock options within the meaning of Section 424 of the Code, which shares have not been disposed by the person who exercised such Replacement Option prior to the Call Date (the "Option Shares"), will be required to surrender the certificates therefor to the Company or the Depositary on the Option Share Termination Date together with a properly executed letter of transmittal. Upon such surrender, such holders will be paid the Call Price for the Option Shares. Upon payment in full of the Call Price for the Option Shares, the surrendered certificates will be transferred to the Company, canceled and retired. From and after the Option Share Termination Date, the Option Shares will no longer be deemed outstanding and all rights of the holders of the Option Shares will cease and terminate. If the Company fails to make the deposit or promptly pay the purchase price for shares of the Special Common Stock as provided in Article Fourth, the Call Price or Put Price, as the case may be, for such shares will thereafter be increased by an amount equal to interest thereon (the "Default Interest") from the date of surrender of the certificates pursuant to Article Fourth at an annual rate equal to two percentage points in excess of the rate of interest publicly announced from time to time by the Bank of America NT&SA in San Francisco, California, as its reference rate until the purchase price therefor, together with the Default Interest, is paid in full and, until such payment in full, the shares of Special Common Stock will continue to be outstanding and owned by the record owner thereof. The right of the holders of the Special Common Stock to exercise the Put will accelerate and the Put will be exercisable immediately upon the occurrence of certain specified insolvency events and until the end of the Put Period (without giving effect to acceleration of the commencement date thereof) and, immediately upon the occurrence of such acceleration, the Call will be null and void and of no further force or effect. VOTING RIGHTS Except as may be required by law and as described below, the holders of record of shares of Common Stock and the holders of record of the Special Common Stock will be entitled to one vote per share for all purposes and will vote together on all matters and not as a separate class or series. For matters to be voted on by the Common Stock and the Special Common Stock together and not as a separate class or series, the presence in person or by proxy of the holders of record as of the applicable record date of a majority of the total number of shares of Common Stock and shares of the Special Common Stock will constitute a quorum. For matters to be voted on by the Common Stock as a separate class, the presence in person or by proxy of 48 the holders of record of a majority of the total number of shares outstanding as of the applicable record date will constitute a quorum of the Common Stock voting separately as a class. For matters to be voted on by the Special Common Stock as a separate class, the presence in person or by proxy of the holders of record of shares of Special Common Stock representing a majority of all of the votes entitled to be cast by the holders of the Special Common Stock outstanding as of the applicable record date will constitute a quorum of the Special Common Stock voting separately as a class. For matters to be voted on by the Special Common Stock as a separate class, and only on such matters, consistent with the rights of the present holders of Shares, a holder of record of a share of the Special Common Stock will be entitled to ten votes on each matter submitted to a vote (whether at a meeting or by written consent) by holders of the Special Common Stock, voting separately as a class, for each such share thereof held of record by such holder on a record date if, with respect to such share, each and every beneficial owner thereof was (1) the beneficial owner of the Shares exchanged therefor in the Merger (the "Premerger Shares") on August 27, 1991, the date of the reincorporation of the Company in the State of Delaware (the "Reincorporation Date"), and at all times until exchanged for shares of Special Common Stock pursuant to the Merger and (2) the beneficial owner of such share of Special Common Stock immediately following the Effective Time and at all times since the Effective Time, subject to certain presumptions set forth in Article Fourth. Although the number of votes to which a present holder of Shares entitled to ten votes cannot exceed that percentage of the votes entitled to be cast which is equal to that percentage of the total outstanding Shares which such Shares represented on August 27, 1991, there is no such limit on the votes entitled to be cast by the holders of the Special Common Stock which has the effect of increasing the percentage of votes to which holders of Premerger Shares beneficially owned as of the Reincorporation Date, including Dr. Salick, are entitled. See "INTRODUCTION--Record Date; Voting Rights; Proxies." Consistent with the Company's certificate of incorporation, the holders entitled to ten votes per share of Special Common Stock will be entitled to make certain transfers thereof without losing the ten-vote right. Holders of shares of the Special Common Stock not entitled to ten votes per share on matters to be voted on by the holders of the Special Common Stock, voting separately as a class, are entitled to one vote per share. Additionally, a beneficial owner of any share of the Special Common Stock beneficially owned by reason of participation in any employee stock option or employee stock purchase plan or other similar individual account employee benefit plan or arrangement of the Company will be deemed for purposes of the ten-vote rights to have been the beneficial owner of the Premerger Shares at the Reincorporation Date and such share of Special Common Stock at the Effective Time if (a) as of the Reincorporation Date, the Premerger Shares for which the Special Common Stock were exchanged, and as of the Effective Time such share of Special Common Stock, was allocated to the account of such beneficial owner under such plan or arrangement, or (b) at the Reincorporation Date and the Effective Time such beneficial owner was the holder, as the case may be, of an option or right to acquire Premerger Shares and the Replacement Option substituted therefor in the Merger, respectively. The distribution of such share to such beneficial owner pursuant to such plan or arrangements, or the purchase by such beneficial owner of such share upon the exercise of an option or a right, as the case may be, will not be deemed to be a change in beneficial ownership and such beneficial owner will be entitled to ten votes per share. Each share of Special Common Stock, whether at any particular time the beneficial owner thereof is entitled to ten votes or less, will be identical to all other shares of Special Common Stock in all other respects and together all shares of Special Common Stock will constitute a single class of shares of the Company. ELECTION OF DIRECTORS From the Closing Date until the Termination Date, the holders of shares of Common Stock, voting separately as a class, will be entitled to elect five Common Stock Directors and the holders of the Special Common Stock, voting separately as a class, will be entitled to elect five Special Common Stock Directors. The absence of a quorum of the holders of the shares of Common Stock will not prevent the election of the Special Common Stock Directors. Conversely, the absence of a quorum of the holders of the Special Common Stock will not prevent the election of the Common Stock Directors. In the absence of either or both quorums, 49 a majority of the holders present in person or by proxy of the class which lacks a quorum will have the power to adjourn for a period of up to thirty days the meeting for the election of the directors which they are entitled to elect from time to time without notice other than announcement at the meeting until a quorum of such class shall be present. From and after the Termination Date, the holders of the Common Stock and the holders of the Special Common Stock will vote together for the election of directors and not as a separate class or series and the right of a holder of Special Common Stock to be entitled to ten votes per share as described above will be of no further force or effect. If the Company fails to deposit funds with the Depositary and promptly pay the purchase price for shares of Special Common Stock upon exercise of the Put or Call, as the case may be, or upon the occurrence of certain insolvency events specified in Article Fourth, then the authorized number of directors constituting the Board, immediately and automatically, without further action of the Board or the stockholders of the Company, will be increased by a number which will, together with the number of Special Common Stock Directors, represent a majority of the authorized number of directors of the Company. In such event, the Special Common Stock Directors then in office will have the sole and exclusive right to elect to the Board the persons to fill all of the new directorships created by such increase in the authorized number of directors. Thereafter, the holders of the Special Common Stock will be entitled to elect, at all subsequent meetings of stockholders at which directors are elected, a number of directors representing a majority of then authorized number of directors of the Company. Such rights of the holders of the Special Common Stock will continue until such time as the aggregate Put Price and/or the Call Price, as the case may be, together with the Default Interest thereon has been paid in full to the holders of Special Common Stock. However, such rights will be of no force or effect if Zeneca or Zeneca PLC purchases and pays for, in accordance with the Merger Agreement, all of the shares of Special Common Stock with respect to which the Put has been exercised. See "THE MERGER AGREEMENT--Obligations of Zeneca PLC Regarding Put" above. SPECIAL VOTING RIGHTS Except as otherwise required by law, until the Termination Date, without (1) the affirmative vote (or written consent) of holders of record of a majority of all of the votes entitled to be cast by the holders of the outstanding Special Common Stock, voting separately as a class, and (2) the affirmative vote (or written consent) of holders of record of a majority of the total number of outstanding shares of Common Stock, voting separately as a class, the Company will not take certain actions including, without limitation, the issuance of securities senior to, or on parity with, the Special Common Stock or the Common Stock, or any securities convertible or exercisable therefor; any merger, consolidation, or recapitalization of the Company; any sale, transfer or other disposition of all or substantially all of the Company's assets to any person; any liquidation, dissolution, winding up or other cessation of the business or operations of the Company; or any amendments to certain provisions of the Certificate of Incorporation (including Article Fourth). LIQUIDATION Upon any liquidation, dissolution or winding up of the Company, prior to any distributions to holders of Common Stock, the holders of shares of Special Common Stock will be entitled to receive, out of the assets of the Company, $42.00 per share or, if appropriate, following a default in payment of the Call Price or the Put Price, the amount of the Call Price or the Put Price, as the case may be, increased by an amount equal to the Default Interest. If the assets of the Company are insufficient to permit the payment to the holders of the Special Common Stock of the full preferential amounts to which they are entitled, then the entire assets will be distributed ratably among the holders of the Special Common Stock then outstanding until payment in full of such amount per share. After payment or distribution to the holders of the Special Common Stock of the full liquidation preference to which they are entitled, the holders of shares of Common Stock will be entitled to receive out of the assets of the Company an amount equal to $42.00 per share thereof before any further payment is made or assets are distributed to the holders of Special Common Stock. If the assets distributable to the holders of shares of Common Stock will be insufficient to permit the payment to them of $42.00 per share, such assets will be distributed ratably among the holders of shares of Common Stock then outstanding until 50 payment in full of such amount per share. After the payment to the holders of shares of Common Stock of $42.00 per share, the remaining assets of the Company available for distribution to stockholders shall be distributed ratably to the holders of shares of the Special Common Stock and the holders of shares of Common Stock then outstanding. 51