EXHIBIT 99.1

 
                            STOCK PURCHASE AGREEMENT

                                 by and between

                          Premier Laser Systems, Inc.

                                      and

                           Ophthalmic Imaging Systems

                                  dated as of

                               February 25, 1998

 
                               TABLE OF CONTENTS
 


                                                                           PAGE
                                                                           ----
                                                                     
 ARTICLE I     THE OFFER.................................................    1
  SECTION 1.1  The Offer.................................................    1
  SECTION 1.2  Ophthalmic Actions........................................    3
 ARTICLE II    AMENDMENT TO RIGHTS PLAN; CLOSING OF THE PRIVATE
               ACQUISITION...............................................    4
                         Amendment to Rights Plan; Closing of the Private
  SECTION 2.1  Acquisition...............................................    4
 ARTICLE III   [NOT USED]................................................    4
 ARTICLE IV    REPRESENTATIONS AND WARRANTIES OF OPHTHALMIC..............    4
  SECTION 4.1  Organization and Qualification; No Subsidiaries...........    4
  SECTION 4.2  Capitalization............................................    5
  SECTION 4.3  Authority Relative to this Agreement......................    5
  SECTION 4.4  No Violation..............................................    6
  SECTION 4.5  SEC Reports and Financial Statements......................    6
                  Compliance with Applicable Laws and Permits; Regulatory
  SECTION 4.6  Matters...................................................    6
  SECTION 4.7  Change of Control.........................................    7
  SECTION 4.8  Litigation................................................    7
  SECTION 4.9  Information...............................................    7
  SECTION 4.10 Employee Benefit Plans....................................    8
  SECTION 4.11 Taxes.....................................................    9
  SECTION 4.12 Intellectual Property.....................................    9
  SECTION 4.13 Contracts.................................................   10
  SECTION 4.14 Voting Requirements.......................................   10
  SECTION 4.15 Absence of Certain Changes................................   10
  SECTION 4.16 Rights Agreement..........................................   10
  SECTION 4.17 Brokers...................................................   11
  SECTION 4.18 Opinion of Investment Banker..............................   11
 ARTICLE V     REPRESENTATIONS AND WARRANTIES OF PREMIER.................   11
  SECTION 5.1  Organization and Qualification............................   11
  SECTION 5.2  Authority Relative to this Agreement......................   11
  SECTION 5.3  No Violation..............................................   12
  SECTION 5.4  Information...............................................   12
  SECTION 5.5  Funds; Reservation of Shares..............................   12
  SECTION 5.6  Intention to Propose a Merger.............................   12
  SECTION 5.7  Ownership of Shares.......................................   12
  SECTION 5.8  SEC Reports and Financial Statements......................   12
  SECTION 5.9  Absence of Certain Changes................................   13
  SECTION 5.10 Capitalization............................................   13
 ARTICLE VI    COVENANTS.................................................   13
  SECTION 6.1  Conduct of Business of Ophthalmic.........................   13
  SECTION 6.2  Covenants of Premier......................................   14
  SECTION 6.3  Access to Information; Confidentiality....................   15
  SECTION 6.4  Efforts...................................................   15
  SECTION 6.5  Public Announcements......................................   16
  SECTION 6.6  Employee Benefit Arrangements; Warrants...................   16
  SECTION 6.7  Notification of Certain Matters...........................   17
  SECTION 6.8  Rights Agreement..........................................   17

 
                                       i

 


                                                                           PAGE
                                                                           ----
                                                                     
  SECTION 6.9  State Takeover Laws.......................................   18
  SECTION 6.10 No Solicitation...........................................   18
  SECTION 6.11 Indemnification...........................................   19
  SECTION 6.12 Conditions................................................   20
 ARTICLE VII   CONDITIONS TO CONSUMMATE THE TRANSACTIONS HEREUNDER.......   20
  SECTION 7.1  Conditions................................................   20
  SECTION 7.2  Conditions to Obligations of Premier......................   20
  SECTION 7.3  Conditions of Premier to Close the Offer..................   20
 ARTICLE VIII  TERMINATION; AMENDMENTS; WAIVER...........................   21
  SECTION 8.1  Termination...............................................   21
  SECTION 8.2  Effect of Termination.....................................   21
  SECTION 8.3  Fees and Expenses.........................................   21
  SECTION 8.4  Amendment.................................................   22
  SECTION 8.5  Extension; Waiver.........................................   22
 ARTICLE IX    MISCELLANEOUS.............................................   22
  SECTION 9.1  Non-Survival of Representations and Warranties............   22
                     General Release of Ophthalmic Executive Officers and
  SECTION 9.2  Directors.................................................   22
  SECTION 9.3  Entire Agreement; Assignment..............................   22
  SECTION 9.4  Validity..................................................   23
  SECTION 9.5  Notices...................................................   23
  SECTION 9.6  Governing Law.............................................   24
  SECTION 9.7  Descriptive Headings......................................   24
  SECTION 9.8  Counterparts..............................................   24
  SECTION 9.9  Parties in Interest.......................................   24
  SECTION 9.10 Certain Definitions.......................................   24
  SECTION 9.11 Specific Performance......................................   24
  SECTION 9.12 Fiduciary Duty............................................   24
  SECTION 9.13 Obligation of Premier.....................................   24

 
                                       ii

 
                           STOCK PURCHASE AGREEMENT
 
  STOCK PURCHASE AGREEMENT (this "Agreement"), is dated as of February 25,
1998, by and between Premier Laser Systems, Inc., a California corporation
("Premier"), and Ophthalmic Imaging Systems, a California corporation
("Ophthalmic").
 
  WHEREAS, the respective Boards of Directors of Premier and Ophthalmic have
approved the acquisition of up to all the outstanding shares of common stock
of Ophthalmic by Premier on the terms and subject to the conditions set forth
in this Agreement;
 
  WHEREAS, pursuant to this Agreement Premier has agreed to commence an
exchange offer (the "Offer") to exchange for each outstanding share of
Ophthalmic's common stock, no par value (the "Common Stock") (including the
associated preferred share purchase rights (the "Rights") issued pursuant to
the Rights Agreement, dated as of December 31, 1997, between Ophthalmic and
American Securities Transfer, Inc., as Rights Agent (the "Rights Agreement"),
which Rights together with the Common Stock are hereinafter referred to as the
"Shares"): (a) $1.75 net in cash (the "Cash Consideration"), (b) that number
of shares of Premier Class A Common Stock, no par value (the "Premier Common
Stock") equal to the Exchange Ratio (as defined herein) (the "Stock
Consideration"), (c) one Premier Class C Warrant (a "Class C Warrant"), and
(d) one Premier Class D Warrant (a "Class D Warrant", and together with a
Class C Warrant, the "Warrants" or the "Warrant Consideration") (the Cash
Consideration, the Stock Consideration and the Warrant Consideration together
constitute the "Offer Consideration");
 
  WHEREAS, the Board of Directors of Ophthalmic (the "Ophthalmic Board") has,
in light of and subject to the terms and conditions set forth herein, (i)
determined that the Offer Consideration and the Offer, and the transactions
contemplated hereby, are fair to and in the best interest of Ophthalmic and
its stockholders; and (ii) resolved to approve and adopt this Agreement and
the transactions contemplated hereby and to recommend acceptance of the Offer
to Ophthalmic's stockholders;
 
  WHEREAS, the respective Boards of Directors of Premier and Ophthalmic
contemplate that upon completion of the Offer, the parties may pursue a merger
providing all stockholders of Ophthalmic remaining after consummation of the
Offer an economic benefit similar to the Offer Consideration;
 
  WHEREAS, Premier and Ophthalmic desire to make certain representations,
warranties, covenants and agreements in connection with the Offer, and also to
prescribe various conditions to the Offer; and
 
  WHEREAS, contemporaneously with the execution and delivery of this
Agreement, Premier and certain stockholders of Ophthalmic will enter into
certain Purchase Agreements providing for the acquisition of Shares by Premier
from the holders named therein in exchange for the same consideration as being
exchanged pursuant to the Offer (the "Private Acquisition");
 
  NOW, THEREFORE, in consideration of the foregoing and the respective
representations, warranties, covenants and agreements set forth herein, and
for other good and valuable consideration, intending to be legally bound
hereby, Premier and Ophthalmic agree as follows:
 
                                   ARTICLE I
 
                                   THE OFFER
 
  SECTION 1.1 The Offer.
 
  (a) Provided that this Agreement shall not have been terminated in
accordance with Section 8.1 of this Agreement and none of the events set forth
in Annex I hereto (the "Exchange Offer Conditions") shall have occurred and be
existing, as promptly as practicable, but in no event later than the fifth
business day from the
 
                                       1

 
date of this Agreement, Premier shall commence (within the meaning of Rule
14d-2 under the Securities Exchange Act of 1934, as amended, including the
rules and regulations promulgated thereunder (the "Exchange Act")), a tender
offer for any and all Shares in exchange for the Offer Consideration and shall
use reasonable best efforts to consummate the Offer. The obligation of Premier
to accept for exchange and to exchange the Offer Consideration for any Shares
tendered pursuant thereto will be subject only to the satisfaction of the
conditions set forth in Annex I hereto. This Offer shall be made by means of a
Prospectus/Offer to Exchange (the "Offer to Purchase") containing the terms
set forth in this Agreement and the conditions set forth in Annex I.
Notwithstanding anything to the contrary in clause (iii) of Annex I hereto,
Premier shall be required to make a reasonable determination that any of the
events set forth in paragraphs (a) through (h) of Annex I shall have occurred
in order to refuse payment of the Offer Consideration for the tendered Shares
or to terminate the Offer in connection with any purported failure to meet a
condition specified in such paragraphs (a) through (h) of Annex I.
 
  (b) The Offer Consideration shall consist of: (x) the Cash Consideration,
(y) the Stock Consideration, and (z) the Warrant Consideration. The Stock
Consideration is equal to that number of shares of Premier Common Stock equal
to the Exchange Ratio. "Exchange Ratio" means the quotient (rounded to the
nearest 1/100,000) determined by dividing $0.25 by closing sales prices for
Premier Common Stock as reported on The Nasdaq Stock Market, Inc. ("NASDAQ")
as published in The Wall Street Journal or, if not published therein, in
another authoritative source) for either (i) the fifteen (15) consecutive
trading days (each, a "Trading Day") ending five Trading Days immediately
preceding the Expiration Date (as defined below) or (ii) the thirty (30)
consecutive Trading Days ending twenty (20) Trading Days prior to the
Expiration Date, whichever yields the fewer number of shares of Premier Common
Stock (the "Premier Average Price"). The Class C Warrants and the Class D
Warrants shall be substantively in the forms attached as Exhibits A and B
hereto, respectively.
 
  (c) Without the prior written consent of Ophthalmic, Premier shall not
decrease the Offer Consideration or change the form of consideration payable
in the Offer, decrease the number of Shares sought to be purchased in the
Offer, impose additional conditions to the Offer or amend any other term of
the Offer in any manner adverse to the holders of Common Stock. The Offer
shall remain open until the date that is 20 business days (as such term is
defined in Rule 14d-1(c)(6) under the Exchange Act) after the commencement of
the Offer (the "Expiration Date"), unless Premier shall have extended the
period of time for which the Offer is open pursuant to, and in accordance
with, the two succeeding sentences or as may be required by applicable law, in
which event the term "Expiration Date" shall mean the latest time and date as
the Offer, as so extended, may expire. Subject to the terms of the Offer and
this Agreement and the satisfaction of all the Exchange Offer Conditions as of
any Expiration Date, Premier shall accept for exchange and exchange the Offer
Consideration for all Shares validly tendered and not withdrawn pursuant to
the Offer as promptly as practicable after such Expiration Date; provided
that, if on any scheduled Expiration Date of the Offer all of the Exchange
Offer Conditions shall not have been satisfied or waived, unless this
Agreement has been terminated pursuant to Section 8.1 hereof, the Offer may,
but need not, be extended from time to time without the consent of Ophthalmic
for such period of time as is reasonably expected by Premier to be necessary
to satisfy the unsatisfied conditions; provided further that the Offer may be
extended by Premier without the consent of Ophthalmic for any period required
by any rule, regulation, interpretation or position of the SEC or the staff
thereof applicable to the Offer.
 
  (d) Concurrently with the commencement of the Offer, Premier shall file with
the Securities and Exchange Commission ("SEC") a Tender Offer Statement on
Schedule 14D-1 in accordance with the Exchange Act with respect to the Offer
(together with all amendments, supplements, and exhibits thereto, including
the Offer to Purchase, the "Schedule 14D-1") and a Registration Statement on
Form S-4 (the "Form S-4") in accordance with the Securities Act of 1933, as
amended (the "Securities Act") to register the Premier Common Stock and the
Warrants to be issued in connection with the Offer (together with all
amendments, supplements, and exhibits thereto, including the Prospectus in the
form of the Offer to Purchase, the "Registration Statement"). The Schedule
14D-1 and the Registration Statement are referred to collectively herein as
the "Offer Documents". Ophthalmic and its counsel shall be given a reasonable
opportunity to review and comment and on the Offer Documents and all
amendments and supplements thereto prior to their filing with the SEC or
dissemination to
 
                                       2

 
stockholders of Ophthalmic. Premier agrees to provide Ophthalmic and its
counsel in writing with any comments Premier and its counsel may receive from
the SEC or its staff with respect to the Offer Documents promptly after
receipt of such comments and shall provide Ophthalmic and its counsel with
reasonable opportunity to review and comment on the response of Premier to
such comments. Premier represents that the Offer Documents will comply in all
material respects with the provisions of applicable federal and state
securities laws, and, on the date filed with the SEC and on the date first
published, sent or given to Ophthalmic's stockholders, shall not contain any
untrue statement of a material fact or omit to state any material fact
required to be stated therein or necessary in order to make the statements
made therein, in light of the circumstances under which they were made, not
misleading, except that no representation is made by Premier with respect to
information supplied by Ophthalmic in writing for inclusion in the Offer
Documents. Ophthalmic shall provide Premier with such information as Premier
may reasonably request in connection with the preparation of the Offer
Documents. Each of Premier and Ophthalmic agrees promptly to correct any
information provided by it for use in the Offer Documents if and to the extent
that it shall have become incomplete, false or misleading in any material
respect and Premier further agrees to take all steps necessary to cause the
Offer Documents as so corrected to be filed with the SEC and to be
disseminated to stockholders of Ophthalmic, in each case, as and to the extent
required by applicable federal and state securities laws.
 
  (e) Notwithstanding any other provision of this Agreement, each holder of
Shares tendered for exchange pursuant to this Offer who would otherwise have
been entitled to receive a fraction of a share of Premier Common Stock (after
taking into account all shares tendered by such holder) shall receive, in lieu
thereof, cash in an amount equal to the fractional part of the Premier Common
Stock multiplied by the "market price" of one share of Premier Common Stock,
payable as part of the Offer Consideration. The "market price" of one share of
Premier Common Stock shall be the closing price of such common stock as
reported on NASDAQ (as published in The Wall Street Journal or, if not
published therein, any other authoritative source) on the last Trading Date
preceding the Expiration Date.
 
  SECTION 1.2 Ophthalmic Actions.
 
  (a) Ophthalmic hereby approves and consents to the Offer and represents,
that the Ophthalmic Board, at a meeting duly called and held, has (i)
determined by unanimous vote of its directors that each of the transactions
contemplated hereby, is fair to and in the best interests of Ophthalmic and
its stockholders, (ii) approved the Offer and adopted this Agreement in
accordance with the California General Corporation Law ("CGCL") and pursuant
to Article Six of the Restated Articles of Incorporation of Ophthalmic, and
(iii) resolved to recommend that the stockholders of Ophthalmic accept the
Offer and tender their Shares thereunder to Premier; provided, however, that
such recommendation and approval may be withdrawn, modified or amended only in
accordance with Section 6.10 of this Agreement. Ophthalmic further represents
that, prior to the execution hereof, Cowen & Company (the "Investment
Banker"), has delivered to the Ophthalmic Board its written opinion that, as
of the date thereof, the financial terms of the Offer are fair, from a
financial point of view to the holders of shares of Common Stock (other than
Premier and its affiliates). Ophthalmic hereby consents to the inclusion in
the Offer Documents of the recommendations of the Ophthalmic Board described
in this Section 1.2(a).
 
  (b) Ophthalmic shall file with the SEC, as promptly as possible after the
filing by Premier of the Schedule 14D-1, a Solicitation/Recommendation
Statement on Schedule 14D-9 in accordance with the Exchange Act (together with
all amendments, supplements, and exhibits thereto, the "Schedule 14D-9"),
which shall contain the recommendation referred to in Section 1.2(a)(iii) of
this Agreement; provided that subject to Section 6.10 of this Agreement, such
recommendation may be withdrawn, modified, or amended. Premier and its counsel
shall be given reasonable opportunity to review and comment on the Schedule
14D-9 prior to its filing with the SEC. Ophthalmic agrees to provide Premier
and its counsel in writing with any comments Ophthalmic or its counsel may
receive from the SEC or its staff with respect to the Schedule 14D-9 promptly
after receipt of such comments. Ophthalmic represents that the Schedule 14D-9
will comply in all material respects with the provisions of applicable federal
and state securities laws and, on the date filed with the SEC and on the date
first published, sent or given to Ophthalmic's stockholders, shall not contain
any untrue statement of a material fact
 
                                       3

 
or omit to state any material fact required to be stated therein or necessary
in order to make the statements made therein, in light of the circumstances
under which they were made, not misleading, except that no representation is
made by Ophthalmic with respect to information supplied by Premier in writing
for inclusion in the Schedule 14D-9. Each of Ophthalmic and Premier agree
promptly to correct any information provided by either of them for use in the
Schedule 14D-9 if and to the extent that it shall have become false or
misleading, and Ophthalmic further agrees to take all steps necessary to cause
the Schedule 14D-9 as so corrected to be filed with the SEC and to be
disseminated to the holders of Shares, in each case, as and to the extent
required by applicable federal and state securities laws.
 
  (c) In connection with the Offer, Ophthalmic shall furnish or cause to be
furnished to Premier with mailing labels, security position listings, any
available non-objecting beneficial owner lists and any available listing or
computer list containing the names and addresses of the record holders of the
Common Stock as of the most recent practicable date and shall furnish Premier
with such additional available information (including, but not limited to,
updated lists of holders of Common Stock and their addresses, mailing labels
and lists of security positions and non-objecting beneficial owner lists) and
such other assistance as Premier or its agents may reasonably request in
communicating the Offer to Ophthalmic's record and beneficial stockholders.
Subject to the requirements of applicable law, and except for such steps as
are necessary to disseminate the Offer Documents and any other documents
necessary to consummate the transactions contemplated hereby, Premier and its
affiliates, associates, agents and advisors, shall keep such information
confidential and use the information contained in any such labels, listings
and files only in connection with the Offer and, if this Agreement shall be
terminated, shall deliver to Ophthalmic all copies of, and extracts and
summaries from, such information then in their possession.
 
                                  ARTICLE II
 
         AMENDMENT TO RIGHTS PLAN; CLOSING OF THE PRIVATE ACQUISITION
 
  SECTION 2.1 Amendment to Rights Plan; Closing of the Private
Acquisition. Provided that this Agreement is not earlier terminated, the
Ophthalmic Board shall amend the Rights Plan in accordance with Section 4.16
simultaneously with the closing of the Private Acquisition.
 
                                  ARTICLE III
 
                                  [NOT USED]
 
                                  ARTICLE IV
 
                 REPRESENTATIONS AND WARRANTIES OF OPHTHALMIC
 
  Ophthalmic represents and warrants to Premier as follows:
 
  SECTION 4.1 Organization and Qualification; No Subsidiaries. Ophthalmic is a
corporation duly organized, validly existing and in good standing under the
laws of the state of California and is in good standing as a foreign
corporation in each jurisdiction where the properties owned, leased or
operated, or the business conducted, by it require such qualification, except
where failure to be in good standing or to so qualify would not have a
Material Adverse Effect on Ophthalmic. Except as set forth in Section 4.1 of
the Ophthalmic Disclosure Schedule, Ophthalmic has the requisite corporate
power and authority and all necessary governmental approvals to own, lease and
operate its properties and to carry on its business as it is now being
conducted, except where the failure to have such power, or authority and
governmental approvals would not, individually or in the aggregate, have a
Material Adverse Effect. The term "Material Adverse Effect on Ophthalmic," as
used in this Agreement, means any change in or effect on the business,
financial condition or results of operations of
 
                                       4

 
Ophthalmic that would have, individually or in the aggregate, a material
adverse impact on Ophthalmic. Ophthalmic has heretofore made available to
Premier a complete and correct copy of its Restated Articles of Incorporation
(including all Certificates of Determination) and By-Laws, each as amended to
the date hereof. Such Restated Articles of Incorporation, By-Laws and
equivalent organizational documents are in full force and effect. Except as
set forth in Section 4.1 or the Ophthalmic Disclosure Schedule, Ophthalmic is
not in violation of any provision of its Restated Articles of Incorporation,
By-Laws, or equivalent organizational documents. Ophthalmic does not have any
subsidiaries.
 
  SECTION 4.2 Capitalization. The authorized capital stock of Ophthalmic
consists of 20,000,000 of shares of Common Stock and 20,000,000 shares of
preferred stock ("Preferred Stock"), of which 100,000 shares are designated
Series A Junior Participating Preferred Stock, no par value ("Junior Preferred
Stock"). As of the close of business on February 25, 1998, 3,905,428 shares of
Common Stock were issued and outstanding, and no shares of Common Stock were
held in treasury. Ophthalmic has no shares of Preferred Stock issued and
outstanding. As of the date hereof, except for (i) 1,514,742 Common Stock
reserved for issuance pursuant to outstanding options granted by Ophthalmic
("Ophthalmic Options"), (ii) 250,000 shares of Common Stock reserved for
issuance pursuant to outstanding warrants ("Ophthalmic Warrants") and (iii)
100,000 shares of Junior Preferred Stock reserved for issuance upon exercise
of the Rights, there are not now, and at the Expiration Date there will not
be, any existing options, warrants, calls, subscriptions, or other rights, or
other agreements or commitments, obligating Ophthalmic to issue, transfer or
sell any shares of capital stock of Ophthalmic or bonds, debentures, notes or
other indebtedness having general voting rights (or convertible into
securities having such rights) of, or other equity interest in, Ophthalmic or
securities convertible into or exchangeable for such shares or equity interest
or obligating Ophthalmic to grant, extend or enter into any such option,
warrant, call, subscription or other right, agreement, arrangement or
commitment other than as set forth in Section 6.1 of the Ophthalmic Disclosure
Schedule. Since February 12, 1998, Ophthalmic has not issued any shares of its
capital stock, except pursuant to Ophthalmic Options and Ophthalmic Warrants
outstanding on such date. All issued and outstanding shares of Common Stock
are and all shares of Common Stock which may be issued pursuant to the
exercise of outstanding Ophthalmic Options and Ophthalmic Warrants will be,
when issued in accordance with the respective terms thereof, duly authorized
and validly issued, fully paid and nonassessable, and such issuance will not
violate any preemptive rights under law or otherwise. Except as contemplated
by the Offer contemplated by this Agreement and pursuant to the Private
Acquisition, there are no outstanding contractual obligations of Ophthalmic to
repurchase, redeem or otherwise acquire any shares of Common Stock or the
capital stock of Ophthalmic.
 
  SECTION 4.3 Authority Relative to this Agreement.
 
  (a) Ophthalmic has the requisite corporate power and authority to execute
and deliver this Agreement and, to the extent required by applicable law or
Ophthalmic's Restated Articles of Incorporation, subject to the approval and
adoption of any Proposed Merger by the stockholders of Ophthalmic, if
required, to consummate the transactions contemplated hereby. The execution
and delivery of this Agreement by Ophthalmic and the consummation by
Ophthalmic of the transactions contemplated hereby have been duly and validly
authorized by all necessary corporate action on the part of Ophthalmic,
subject, in the case of the Proposed Merger, to any necessary approval thereof
by the stockholders of Ophthalmic. This Agreement has been duly and validly
executed and delivered by Ophthalmic, and, assuming this Agreement constitutes
a valid and binding obligation of Premier, this Agreement constitutes a valid
and binding agreement of Ophthalmic, enforceable against Ophthalmic in
accordance with its terms (except in all cases as such enforceability may be
limited to applicable bankruptcy, insolvency, reorganization, moratorium, or
similar laws affecting the enforcement of creditor's rights generally and
except that the availability of the equitable remedy of specific performance
or injunctive relief is subject to the discretion of any court before which
any proceeding may be brought).
 
  (b) Except as set forth in this Section 4.3 of the Ophthalmic Disclosure
Schedule, other than in connection with, or in compliance with, the provisions
of the CGCL with respect to the transactions contemplated hereby, the federal
securities laws, the securities laws of the various states, the rules of
NASDAQ, and other than notices to or filings with the Internal Revenue Service
or the Pension Benefit Guaranty Corporation with respect to
 
                                       5

 
employee benefit plans, or under the Hart-Scott-Rodino Antitrust Improvements
Act of 1976, as amended (the "HSR Act"), no authorization, consent or approval
of, or filing with, any Governmental Entity (as hereinafter defined) is
necessary for the consummation by Ophthalmic of the transactions contemplated
by this Agreement other than authorizations, consents and approvals the
failure to obtain, or filings the failure to make, which would not,
individually in the aggregate, have a Material Adverse Effect on Ophthalmic.
As used in this Agreement, the term "Governmental Entity" means any government
or subdivision thereof, domestic, foreign or supranational or any
administrative, governmental or regulatory authority, agency, commission,
tribunal or body, domestic, foreign or supranational.
 
  SECTION 4.4 No Violation. Neither the execution or delivery of this
Agreement by Ophthalmic nor the consummation by Ophthalmic of the transactions
contemplated hereby will (i) constitute a breach or violation of any provision
of the Restated Articles of Incorporation or By-Laws of Ophthalmic, (ii)
except as set forth in Section 4.4 of the Ophthalmic Disclosure Schedule,
constitute a breach, violation or default (or any event which, with notice or
lapse of time or both, would constitute a default) under, or result in the
termination of, or accelerate the performance required by, or result in the
creation of any lien or encumbrance upon any material property or asset of
Ophthalmic under, any note, bond, mortgage, indenture, deed of trust, license,
lease, agreement or other instrument to which Ophthalmic, or by which it or
any of its properties or assets, are bound, or (iii) subject to the receipt of
the requisite consents, approvals, or authorizations of, or filings with
Governmental Entities under federal securities laws, applicable corporate and
securities laws, the rules of NASDAQ and the Boston Stock Exchange, and laws
relating to employee benefit plans, conflict with or violate any order,
judgment or decree, or to the knowledge of Ophthalmic, any statute, ordinance,
rule or regulation applicable to Ophthalmic, or by which it or any of its
properties or assets may be bound or affected, other than, in the case of the
foregoing clauses (ii) or (iii), conflicts, breaches, violations, defaults,
terminations, accelerations or creation of liens and encumbrances which,
individually or in the aggregate, would not have a Material Adverse Effect on
Ophthalmic.
 
  SECTION 4.5 SEC Reports and Financial Statements. Ophthalmic has filed with
the SEC, and has made available to Premier, copies of all forms, reports and
documents ("Ophthalmic SEC Reports") required to be filed by it since
September 1, 1994 under the Securities Act or the Exchange Act. None of such
Ophthalmic SEC Reports (as of their respective filing dates) contained any
untrue statement of a material fact or omitted to state a material fact
required to be stated therein or necessary in order to make the statements
therein, in light of the circumstances under which they were made, not
misleading (except any statement or omission therein which as been corrected
or otherwise disclosed or updated in a subsequent Ophthalmic SEC Report). The
audited and unaudited consolidated financial statements of Ophthalmic included
in any Ophthalmic SEC Report on Form 10-QSB or Form 10-KSB have been prepared
in accordance with generally accepted accounting principles applied on a
consistent basis (except as otherwise stated in such financial statements,
including the related notes or, in the case of unaudited statements, as
permitted by Form 10-QSB of the SEC rules), comply as to form in all material
respects with applicable accounting requirements and the published rules and
regulations of the SEC with respect thereto and fairly present the financial
position of Ophthalmic as of the dates thereof and the results of its
operations and changes in financial position for the periods then ended,
subject, in the case of the unaudited financial statements, to year-end audit
adjustments, and except for the absence of certain footnote information in the
unaudited statements. Except as set forth in Section 4.5 of the Ophthalmic
Disclosure Schedule, Ophthalmic does not have any liabilities or obligations
of any nature (whether absolute, accrued, contingent, unmatured, unaccrued,
unliquidated, unasserted, conditional or otherwise), except for liabilities or
obligations (i) reflected or reserved against on the balance sheet as at
November 30, 1997 (including the notes thereto and the other disclosure made
in Ophthalmic's Form 10-QSB for the quarter ended November 30, 1997) included
in the Ophthalmic SEC Reports, or (ii) incurred in the ordinary course of
business consistent with past practice since such date.
 
  SECTION 4.6 Compliance with Applicable Laws and Permits; Regulatory
Matters.  Except as set forth in Section 4.6 of the Ophthalmic Disclosure
Schedule, to the knowledge of Ophthalmic, it has in effect and holds all
permits, licenses, orders, authorizations, registrations, approvals and other
analogous instruments, and
 
                                       6

 
Ophthalmic has made all filings and registrations and the like necessary or
required by law to conduct its business as presently conducted, other than
such permits, licenses, orders, authorizations, registrations, approvals, and
other instruments, the absence of which do not have a Material Adverse Effect
on Ophthalmic. Ophthalmic has not received any written governmental notices
within two years of the date hereof of any violation by Ophthalmic of any such
laws, rules, regulations or orders. Except as set forth in Section 4.6 of the
Ophthalmic Disclosure Schedule or where the failure to comply would not have a
Material Adverse Effect, to the knowledge of Ophthalmic, Ophthalmic is not in
default or noncompliance under any (a) permits, consents, or similar
instruments, and (b) the business and local and county laws, ordinances,
regulations, judgments, orders, decrees or rules of any court, arbitrator or
governmental, regulatory or administrative agency or entity, other than such
default or noncompliance which is not reasonably likely to have a Material
Adverse Effect on Ophthalmic. Without limiting the generality of the
foregoing, except as set forth in Section 4.6 of the Ophthalmic Disclosure
Schedule, all of the products presently marketed by Ophthalmic have been
approved or cleared to market pursuant to valid and subsisting Premarket
Approval or Section 510(k) Clearances issued by the United States Food and
Drug Administration ("FDA"). Ophthalmic has never conducted any clinical
trials which have required Investigational Device Exemptions ("IDE's"). No
written notification has been furnished to Ophthalmic of any medical
complications arising in connection with or resulting from clinical trials
conducted by Ophthalmic either directly or under its direction, or from the
use of its products following FDA approval or clearance. Ophthalmic has not
received any written complaint nor has Steven Verdooner, during the past six
months, been made aware of any oral complaint made with respect to such
procedures and no Medical Device Reports have been filed by Ophthalmic or have
been required to be filed. Except as set forth in Section 4.6 of the
Ophthalmic Disclosure Schedule, the design, manufacture and distribution of
all of Ophthalmic products, to the extent required, has been conducted, and
shall continue through the Expiration Date to be conducted, substantially in
accordance with "good manufacturing practices" as required by the FDA.
 
  SECTION 4.7 Change of Control. Except as provided by the terms of any
Ophthalmic Warrant, any Ophthalmic stock option plan, or any Ophthalmic
Options, or as set forth on Section 4.7 of the Ophthalmic Disclosure Schedule,
the transactions contemplated by this Agreement will not constitute a "change
of control" under, require the consent from or the giving of notice to a third
party pursuant to, permit a third party to terminate or accelerate vesting or
repurchase rights, or create any other detriment under the terms, conditions
or provisions of any material note, bond, mortgage, indenture, license, lease,
contract, agreement or other instrument or obligation to which Ophthalmic is a
party or by which it or any of its properties or assets may be bound, except
where the adverse consequences resulting from such change of control or where
the failure to obtain such consents or provide such notices would not,
individually or in the aggregate, have a Material Adverse Effect on
Ophthalmic.
 
  SECTION 4.8 Litigation. Except as disclosed in an SEC Report or in Section
4.8 of the Ophthalmic Disclosure Schedule, or otherwise fully covered by
insurance, there is no suit, claim, action, proceeding or investigation
pending or, to the knowledge of Ophthalmic, threatened, against Ophthalmic,
individually or in the aggregate, which would have a Material Adverse Effect
on Ophthalmic or would reasonably be expected to prevent or materially delay
the consummation of the transactions contemplated by this Agreement. Except as
disclosed in the Ophthalmic SEC Reports filed prior to the date of this
Agreement, Ophthalmic is not subject to any outstanding order, writ,
injunction or decree which, individually or in the aggregate, would have a
Material Adverse Effect on Ophthalmic or would reasonably be expected to
prevent or materially delay the consummation of the transactions contemplated
hereby.
 
  SECTION 4.9 Information. None of the written information supplied by
Ophthalmic (other than projections of future financial performance) expressly
for inclusion or incorporation by reference in the Offer Documents, will, at
the time filed with the SEC, contain any untrue statement of a material fact
or omit to state any material fact required to be stated therein or necessary
in order to make the statements made therein, in light of the circumstances
under which they were made, not misleading. Notwithstanding the foregoing, no
representation is made by Ophthalmic with respect to (i) any forward-looking
information which may have been supplied by Ophthalmic, whether or not
included by Premier in any Offer Document or (ii) statements made in any of
the foregoing documents based upon information supplied by Premier.
 
                                       7

 
  SECTION 4.10 Employee Benefit Plans.
 
  (a) Section 4.10(a)/(b) of the Ophthalmic Disclosure Schedule includes a
complete list of all material employee benefit plans and programs providing
benefits to any employee or former employee of Ophthalmic sponsored or
maintained by Ophthalmic or to which Ophthalmic contributes or is obligated to
contribute ("Plans") and all written employment, severance, consulting and
other compensation contracts between Ophthalmic and any current or former
director, officer, or employee thereof ("Employment Contracts"). Ophthalmic is
not party to any oral Employment Contracts that are not terminable at will.
Without limiting the generality of the foregoing, the term "Plans" includes
all employee welfare benefit plans within the meaning of Section 3(1) of the
Employee Retirement Income Security Act of 1974, as amended, and the
regulations thereunder ("ERISA"), and all employee pension benefit plans
within the meaning of Section 3(2) of ERISA.
 
  (b) With respect to each Plan, Ophthalmic has made available to Premier (to
the extent requested) a true, correct and complete copy of: (i) all plan
documents, benefit schedules, trust agreements, and insurance contracts and
other funding vehicles; (ii) the most recent Annual Report (Form 5500 Series)
and accompanying schedule, if any; (iii) the current summary plan description,
if any; (iv) the most recent annual financial report, if any; (v) the most
recent actuarial report, if any; (vi) the most recent determination letter
from the United States Internal Revenue Service (the "IRS"), if any; and (vii)
each Employment Contract.
 
  (c) Except as set forth in Section 4.10(d) of the Ophthalmic Disclosure
Schedule, all Plans are in compliance, in all material respects with all
applicable provisions of ERISA, the Code and all laws and regulations
applicable to the Plans. With respect to each Plan that is intended to be a
"qualified plan" within the meaning of Section 401(a) of the Code ("Qualified
Plans"), the IRS has issued a favorable determination letter.
 
  (d) Except as set forth in Section 4.10(d) of the Ophthalmic Disclosure
Schedule, all contributions required to be made by Ophthalmic to any Plan
under applicable law or regulation or by any plan document or other
contractual undertaking, and all premiums due or payable with respect to
insurance policies funding any Plan, have been timely made or paid in full or,
to the extent not required to be made or paid, have been fully reflected in
the financial statements of Ophthalmic included in the Ophthalmic SEC Reports
to the extent required under generally accepted accounting principles.
 
  (e) No Plan is subject to Title IV or Section 302 of ERISA or Section 412 or
4971 of the Code. Without limiting the generality of the foregoing, no Plan is
a "multi-employer plan" within the meaning of Section 4001(a)(3) of ERISA (a
"Multi-Employer Plan") or a plan that has two or more contributing sponsors at
least two of whom are not under common control, within the meaning of Section
4063 of ERISA and which is subject to Title IV of ERISA (a "Multiple Employer
Plan").
 
  (f) There does not now exist, nor do any circumstances exist that would
reasonably be expected to result in, any liability under (i) Title IV of
ERISA, (ii) Section 302 of ERISA, (iii) Sections 412 and 4971 of the Code,
(iv) the continuation coverage requirements of Section 601 et seq. of ERISA
and Section 4980B of the Code, or (v) corresponding or similar provisions of
foreign laws or regulations, other than a liability that arises solely out of,
or relate solely to, the Plans, that would be a liability of Ophthalmic or any
of its subsidiaries following the Expiration. Without limiting the generality
of the foregoing, (i) neither of Ophthalmic nor any ERISA Affiliate of
Ophthalmic has engaged in any transaction described in Section 4069 or Section
4204 or 4212 of ERISA, (ii) no liability under Title IV or a violation of
Section 302 of ERISA has been incurred by Ophthalmic that has not been
satisfied in full, and Ophthalmic is not aware of any condition that exists
that presents a material risk to Ophthalmic of incurring any such liability,
other than liability for premiums due to the Pension Benefit Guaranty
Corporation (which premiums have been paid when due) and for contributions due
to a pension plan (which contributions have been paid through the end of
1997), and (iii) no Plan or any trust established thereunder has incurred any
"accumulated funding deficiency" (as defined in Section 302 of ERISA and
Section 412 of the Code), whether or not waived, as of the last day of the
most recent fiscal year of each Plan ended prior to the Expiration Date. An
"ERISA Affiliate" means any entity, trade or business that is a member of a
group
 
                                       8

 
described in Section 414(b), (c), (m) or (o) of the Code or Section 4001(b)(1)
of ERISA that includes Ophthalmic or any of its subsidiaries, or that is a
member of the same "controlled group" as Ophthalmic or any of its
subsidiaries, pursuant to Section 4001(a)(14) of ERISA.
 
  (g) To the knowledge of Ophthalmic, there are no pending, threatened or
anticipated claims by or on behalf of any Plan, by any employee or beneficiary
covered under any such Plan, or otherwise involving any such Plan (other than
routine claims for benefits).
 
  SECTION 4.11 Taxes.
 
  (a) Except as set forth in Section 4.11 of the Ophthalmic Disclosure
Schedule, Ophthalmic has (i) timely filed all income Tax Returns (as
hereinafter defined), and all other material Tax Returns required to be filed
by or with respect to it, or requests for extensions have been filed, granted,
and have not expired, for the periods ending on or after December 31, 1996,
and on or before the date of the most recent fiscal year and immediately
preceding the date hereof, and to the knowledge of Ophthalmic all such Tax
Returns are true, correct and complete in all material respects, and (ii) to
the knowledge of Ophthalmic, all Taxes (as hereinafter defined) shown as due
and payable on such Tax Returns have been paid, and (iii) made adequate
provision in Ophthalmic's financial statements for payment of all Taxes
anticipated to be payable in respect of all taxable periods or portions
thereof ending on or before the date hereof, except where the failures to so
file or pay or make adequate provision would not, individually or in the
aggregate, have a Material Adverse Effect on Ophthalmic. There are no
outstanding agreements or waivers extending the statutory period of limitation
applicable to any Tax Return of Ophthalmic. Ophthalmic (i) has not been a
member of a group filing consolidated returns for federal income tax purposes,
or (ii) is not a party to a Tax sharing or Tax indemnity agreement or any
other agreement of a similar nature that remains in effect. There is no audit
examination, deficiency, refund litigation, proposed adjustment or matter in
controversy with respect to any Taxes due and owing by Ophthalmic which would,
individually or in the aggregate, have a Material Adverse Effect on
Ophthalmic. There are no Tax liens upon any of the assets or property of
Ophthalmic, except liens for current Taxes not yet due and payable. As soon as
practicable after the public announcement of the execution of this Agreement,
Ophthalmic will provide Premier with written schedules with respect to income
taxes of (i) the taxable years of Ophthalmic as to which the statutes of
limitations with respect to Taxes have not expired and (ii) with respect to
such taxable years, those years for which examinations have been completed,
those years for which examinations are presently being conducted, those years
for which examinations have not been initiated and those years for which
required Tax Returns have not yet been filed.
 
  (b) For purposes of this Agreement, the term "Taxes" means all taxes, levies
or other assessments, including, without limitation, income, gross receipts,
excise, property, sales, license, payroll, withholding and franchise taxes,
imposed by the United States or any state or local government or subdivision
or agency thereof, including any interest, penalties or additions thereto. For
purposes of this Agreement, the term "Tax Return" means any report, return or
other information or document required to be supplied to a taxing authority in
connection with Taxes.
 
  SECTION 4.12 Intellectual Property.
 
  (a)(i) Ophthalmic owns, has the right to acquire or is licensed or otherwise
has the right to use (in each case, free and clear of any liens or
encumbrances of any kind), all Intellectual Property (as defined below) used
in or necessary for the conduct of its business as currently conducted, (ii)
no claims are pending or, to the knowledge of Ophthalmic, threatened, that
Ophthalmic is infringing on or otherwise violating the rights of any person
with regard to any Intellectual Property, and (iii) to the knowledge of
Ophthalmic, no person is infringing on or otherwise violating any right of
Ophthalmic with respect to any Intellectual Property owned by and/or licensed
to Ophthalmic.
 
  (b) For purposes of this Agreement, "Intellectual Property" shall mean
material patents, copyrights, trademarks (registered or unregistered), service
marks, brand names, trade dress, trade names, the goodwill associated with the
foregoing and registrations in any jurisdiction of, and applications in any
jurisdiction to
 
                                       9

 
register, the foregoing; and trade secrets and rights in any jurisdiction to
limit the use or disclosure thereof by any person.
 
  SECTION 4.13 Contracts. Each material note, bond, mortgage, indenture,
lease, license, contract, agreement or other instrument or obligation to which
Ophthalmic is a party or by which it or any of its properties or assets may be
bound (the "Material Contracts") is in full force and effect, except where
failure to be in full force and effect would not have a Material Adverse
Effect on Ophthalmic, and there are no defaults by Ophthalmic or, to
Ophthalmic's knowledge, any other party thereto, thereunder, except those
defaults that would not have a Material Adverse Effect on Ophthalmic.
 
  SECTION 4.14 Voting Requirements. No vote of the holders of the class or
series of Ophthalmic's capital stock is necessary in connection with this
Agreement, except as may be required in connection with the approval of the
Proposed Merger.
 
  SECTION 4.15 Absence of Certain Changes. Except as disclosed in the
Ophthalmic SEC Reports filed prior to the date of this Agreement or in Section
4.15 of the Ophthalmic Disclosure Schedule, there has not been, since August
31, 1997, any event that has had or that is reasonably expected to have a
Material Adverse Effect on Ophthalmic. Except as disclosed in the Ophthalmic
SEC Reports filed prior to the date of this Agreement or in Section 4.15 of
the Ophthalmic Disclosure Schedule, since August 31, 1997, Ophthalmic has
conducted its business only in the ordinary course of business consistent with
past practices and there has not been, directly or indirectly:
 
    (i) any exchange or grant by Ophthalmic or any increase in compensation
  to any director or executive officer of Ophthalmic or, except in the
  ordinary course of business and consistent with past practice or as
  required under employment agreements in effect as of or prior to the date
  of this Agreement, of any employee of Ophthalmic;
 
    (ii) any grant by Ophthalmic to any such director, executive officer or
  employee of any increase in severance or termination pay, except as
  required under employment, severance or termination agreements or plans in
  effect as of the date of this Agreement;
 
    (iii) except as contemplated by this Agreement, any entry by Ophthalmic
  into any employment, severance or termination agreement with any such
  director or executive officer, or, except in the ordinary course of
  business consistent with past practice, employee;
 
    (iv) except in the ordinary course of business and consistent with past
  practice or as required under employment agreements in effect as of or
  prior to the date of this Agreement, any material adoption or material
  increase in exchanges to or benefits under any profit sharing, bonus,
  deferred compensation, savings, insurance, pension, retirement or other
  employee benefit plan for or with any employees of Ophthalmic;
 
    (v) any change in accounting methods, principles or practices by
  Ophthalmic materially affecting its assets, liabilities or business, except
  insofar as may have been required by change in generally accepted
  accounting principles; or
 
    (vi) any agreement to do any of the things described in the preceding
  clauses (i) through (v).
 
  SECTION 4.16 Rights Agreement. The Ophthalmic Board has duly authorized and
Ophthalmic will execute an amendment (the "Rights Agreement Amendment") to the
Rights Agreement (without redeeming the Rights) which will permit the
execution or delivery of this Agreement, the making of the Offer, the
acquisition of Shares pursuant to the Offer and the consummation of the
Proposed Merger without (i) causing any Rights issued pursuant to the Rights
Agreement to become exercisable or to separate from the stock certificates to
which they are attached, (ii) causing Premier or any of its Affiliates to be
an Acquiring Person (as each such term is defined in the Rights Agreement), or
(iii) triggering other provisions of the Rights Agreement, including giving
rise to a Distribution Date (as such term is defined in the Rights Agreement),
and the Rights Agreement Amendment shall be in full force and effect from and
after the date hereof until such time as, after being advised
 
                                      10

 
by its outside counsel with respect to fiduciary obligations, the Board of
Directors of Ophthalmic determines in good faith by a majority vote that it is
necessary to terminate or revise such amendment or the Rights Agreement in the
exercise of its fiduciary obligations under applicable law.
 
  SECTION 4.17 Brokers. Except for the engagement of the Investment Banker,
none of Ophthalmic, or any of its officers, directors or employees has
employed any broker or finder or incurred any liability for any brokerage
fees, commissions or finder's fees in connection with the transactions
contemplated by this Agreement.
 
  SECTION 4.18 Opinion of Investment Banker. Ophthalmic has received the
written opinion of the Investment Banker to the effect that, as of the date
such opinion, the financial terms of the Offer are fair, from a financial
point of view to the holders of shares of Common Stock (other than Premier and
its affiliates).
 
                                   ARTICLE V
 
                   REPRESENTATIONS AND WARRANTIES OF PREMIER
 
  Premier represents and warrants to Ophthalmic as follows:
 
  SECTION 5.1 Organization and Qualification. Premier is a corporation duly
organized, validly existing and in good standing under the laws of its state
or jurisdiction of incorporation and is in good standing as a foreign
corporation in each other jurisdiction where the properties owned, leased or
operated, or the business conducted, by it require such qualification and
where failure to be in good standing or to so qualify would have a Material
Adverse Effect on Premier. Premier has the requisite corporate power and
authority and all necessary governmental approvals to own, lease and operate
its properties and to carry on its business as it is now being conducted,
except where the failure to have such power, or authority and governmental
approvals would not, individually or in the aggregate, have a Material Adverse
Effect. The term "Material Adverse Effect on Premier", as used in this
Agreement, means any change in or effect on the business, financial condition
or results of operations of Premier or any of its subsidiaries that would,
individually or in the aggregate, be materially adverse to Premier and its
subsidiaries taken as a whole. Premier has heretofore made available to
Ophthalmic a complete and correct copy of its Articles of Incorporation
(including all Certificates of Determination) and By-Laws, each as amended to
the date hereof. Such Articles of Incorporation, By-Laws and equivalent
organizational documents are in full force and effect. Premier is not in
violation of any provision of its Articles of Incorporation, By-Laws, or
equivalent organizational documents.
 
  SECTION 5.2 Authority Relative to this Agreement.
 
  (a) Premier has full corporate power and authority to execute and deliver
this Agreement and to consummate the transactions contemplated hereby. The
execution and delivery of this Agreement and the consummation of the
transactions contemplated hereby have been duly and validly authorized by the
Board of Directors of Premier and no other corporate proceedings on the part
of Premier is necessary to authorize this Agreement or to consummate the
transactions so contemplated. This Agreement has been duly and validly
executed and delivered by Premier and, assuming this Agreement constitutes a
valid and binding obligation of Ophthalmic, this Agreement constitutes a valid
and binding agreement Premier, enforceable against Premier in accordance with
its terms.
 
  (b) Other than in connection with, or in compliance with, the provisions of
the CGCL with respect to the transactions contemplated hereby, the Exchange
Act, the securities laws of the various states, no authorization, consent or
approval of, or filing with, any Governmental Entity is necessary for the
consummation by Premier of the transactions contemplated by this Agreement
other than authorizations, consents and approvals the failure to obtain, or
filings the failure to make, which would not, in the aggregate, have a
Material Adverse Effect on Premier.
 
                                      11

 
  SECTION 5.3 No Violation. Neither the execution or delivery of this
Agreement by Premier nor the consummation by Premier of the transactions
contemplated hereby will (i) constitute a breach or violation of any provision
of the Articles of Incorporation or By-Laws of Premier, (ii) constitute a
breach, violation or default (or any event which, with notice or lapse of time
or both, would constitute a default) under, or result in the termination of,
or accelerate the performance required by, or result in the creation of any
lien or encumbrance upon any of the material property or asset of Premier or
any of its subsidiaries under, any note, bond, mortgage, indenture, deed of
trust, license, lease, agreement or other instrument to which Premier or any
of its subsidiaries is a party or by which they or any of their respective
properties or assets are bound, or (iii) subject to the receipt of the
requisite consents, approvals, or authorizations of, or filings with
Governmental Entities under federal securities laws, applicable corporate and
securities laws, the rules of NASDAQ and laws relating to employee benefit
plans, conflict with or violate any order, judgment or decree, or to the
knowledge of Premier, any statute, ordinance, rule or regulation applicable to
Premier, or by which it or any of its properties or assets may be bound or
affected, other than, in the case of the foregoing clauses (ii) or (iii),
conflicts, breaches, violations, defaults, terminations, accelerations or
creation of liens and encumbrances which, individually or in the aggregate,
would not have a Material Adverse Effect on Premier.
 
  SECTION 5.4 Information. None of the information supplied by Premier in
writing (other than projections of future financial performance) specifically
for inclusion or incorporation by reference in (i) the Schedule 14D-9, or (ii)
the Other Filings will, at the respective times filed with the SEC or other
Governmental Entity contain any untrue statement of a material fact or omit to
state any material fact required to be stated therein or necessary in order to
make the statements made therein, in light of the circumstances under which
they were made, not misleading. Notwithstanding the foregoing, no
representation is made by Premier with respect to statements made in any of
the foregoing documents based upon information supplied in writing by
Ophthalmic.
 
  SECTION 5.5 Funds; Reservation of Shares. Premier has on the date hereof and
will have at the time of acceptance for exchange and exchange of Shares
pursuant to the Offer and at the Expiration Date, the funds necessary and will
have reserved for issuance the Premier Common Stock, the Premier Common Stock
issuable upon exercise of the Warrants and the Warrants to consummate the
Offer and the transactions contemplated thereby on a timely basis in
accordance with this Agreement, which Premier Common Stock and Warrants when
issued, will be duly authorized and validly issued, fully paid and
nonassessable, and such issuance will not violate any preemptive rights under
law or otherwise.
 
  SECTION 5.6 Intention to Propose a Merger. As of the date hereof, Premier
presently intends to, at a reasonable time following its acceptance for
exchange and exchange for shares pursuant to the Offer, propose a merger with
Premier providing holders of shares of Common Stock at such time an economic
benefit similar to that of the Offer Consideration (the "Proposed Merger").
 
  SECTION 5.7 Ownership of Shares. Except as disclosed on the latest Schedule
13D as filed by Premier with the SEC prior to the date of this Agreement with
respect to the Common Stock, none of Premier or its Subsidiaries or affiliates
owns (beneficially or otherwise) any shares of Common Stock. From the date of
this Agreement through the Expiration Date, except for those Private
Acquisitions entered into concurrently herewith, none of Premier or its
Subsidiaries or affiliates shall purchase or otherwise acquire beneficial
ownership of any additional shares of Common Stock.
 
  SECTION 5.8 SEC Reports and Financial Statements. Premier has filed and has
made available to Ophthalmic all forms, reports and documents ("Premier SEC
Reports") required to be filed by it with the SEC since April 1, 1994. None of
such Premier SEC Reports (as of their respective filing dates) contained any
untrue statement of a material fact or omitted to state a material fact
required to be stated therein or necessary in order to make the statements
therein, in light of the circumstances under which they were made, not
misleading (except any statement or omission therein which as been corrected
or otherwise disclosed or updated in a subsequent Premier SEC Report). The
audited and unaudited consolidated financial statements of Premier included in
any Premier SEC Report on Form 10-Q or Form 10-K have been prepared in
accordance with generally accepted
 
                                      12

 
accounting principles applied on a consistent basis (except as otherwise
stated in such financial statements, including the related notes or, in the
case of unaudited statements, as permitted by Form 10-Q of the SEC rules),
comply as to form in all material respects with applicable accounting
requirements and the published rules and regulations of the SEC with respect
thereto and fairly present the financial position of Premier as of the dates
thereof and the results of its operations and changes in financial position
for the periods then ended, subject, in the case of the unaudited financial
statements, to year-end audit adjustments, and except for the absence of
certain footnote information in the unaudited statements. Premier does not
have any liabilities or obligations of any nature (whether absolute, accrued,
contingent, unmatured, unaccrued, unliquidated, unasserted, conditional or
otherwise), except for liabilities or obligations (i) reflected or reserved
against on the balance sheet as at December 31, 1997 (including the notes
thereto and the other disclosure made in Ophthalmic's Form 10-Q for the
quarter ended December 31, 1997) included in the Premier SEC Reports, or (ii)
incurred in the ordinary course of business consistent with past practice
since such date, in each case of clauses (i) and (ii) which, individually or
in the aggregate, would not have a Material Adverse Effect on Premier.
 
  SECTION 5.9 Absence of Certain Changes. Except as disclosed in the Premier
SEC Reports filed prior to the date of this Agreement and made available to
Ophthalmic, there has not been since March 31, 1997 any event that has had or
that is reasonably expected to have a Material Adverse Effect on Premier.
 
  SECTION 5.10 Capitalization. The Premier Common Stock and Warrants (i) when
issued upon exchange for the Shares in accordance with the Offer and (ii) in
the case of Premier Common Stock if and when issued pursuant to the Warrants
in accordance with the respective terms thereof, will be duly authorized,
validly issued, fully paid, nonassessable and such issuances will not violate
any pre-emptive rights under applicable laws, Premier's Articles of
Incorporation or By-Laws, material contract or agreement or otherwise.
 
                                  ARTICLE VI
 
                                   COVENANTS
 
  SECTION 6.1 Conduct of Business of Ophthalmic. Except as contemplated by
this Agreement or as expressly agreed to in writing by Premier, during the
period from the date of this Agreement to the earliest of (a) August 30, 1998,
(b) the termination of this Agreement, or (c) the closing of the Proposed
Merger, Ophthalmic will conduct its operations according to its ordinary and
usual course of business and consistent with past practice and will use its
reasonable efforts, to preserve intact the business organization of
Ophthalmic, to keep available the services of its and their present officers
and key employees, and to preserve the good will of those having business
relationships with it. Without limiting the generality of the foregoing, and
except as (y) otherwise expressly provided in this Agreement, or (z) required
by law, prior to the earlier of the Expiration Date or the termination of this
Agreement, Ophthalmic will not, without the prior written consent of Premier
(which consent shall not be unreasonably withheld):
 
    (i) except with respect to annual bonuses made in the ordinary course of
  business consistent with past practice, adopt or amend in any material
  respect any bonus, profit sharing, compensation, severance, termination,
  stock option, stock appreciation right, pension, retirement, employment or
  other employee benefit agreement, trust, plan or other arrangement for the
  benefit or welfare of any director, officer or employee of Ophthalmic or
  increase in any manner the compensation or fringe benefits of any director,
  officer or employee of Ophthalmic or pay any benefit not required by any
  existing agreement or place any assets in any trust for the benefit of any
  director, officer or employee of Ophthalmic (in each case, except with
  respect to employees, non-executive officers and directors in the ordinary
  course of business consistent with past practice);
 
    (ii) incur any material indebtedness for borrowed money (other than under
  existing lines of credit or under that certain factoring arrangement with
  Imperial Bank dated as November 18, 1997) or guarantee any such
  indebtedness of another person, issue or sell any debt securities or
  warrants or other rights to acquire any debt securities of Ophthalmic,
  guarantee any debt securities of another person, enter into any "keep
 
                                      13

 
  well" or other agreement to maintain any financial statement condition of
  another person or enter into any arrangement having the economic effect of
  any of the foregoing, or make any loans or advances outside the ordinary
  course of business to, or capital contributions to, or investments in, any
  other person;
 
    (iii) expend funds for capital expenditures (as determined under
  generally accepted accounting principles) in excess of $100,000 per fiscal
  quarter;
 
    (iv) sell, lease, license, mortgage or otherwise encumber or subject to
  any lien or otherwise dispose of any of its properties or assets other than
  immaterial properties or assets (or immaterial portions of properties or
  assets), except (i) in the ordinary course of business consistent with past
  practice or (ii) pursuant to contracts or agreements in force as of the
  date of this Agreement;
 
    (v) (x) declare, set aside or pay any dividends on, or make any other
  distributions in respect of, any of its capital stock, (y) split, combine
  or reclassify any of its capital stock or issue or authorize the issuance
  of any other securities in respect of, in lieu of or in substitution for
  shares of its capital stock, or (z) purchase, redeem or otherwise acquire
  any shares of capital stock of Ophthalmic or any other securities thereof
  or any rights, warrants or options to acquire any such shares or other
  securities;
 
    (vi) except pursuant to the exercise of outstanding Ophthalmic Options or
  Ophthalmic Warrants, or as disclosed in Section 6.1 of the Ophthalmic
  Disclosure Schedule, authorize for issuance, issue, deliver, sell or agree
  or commit to issue, sell or deliver (whether through the issuance or
  granting of options, warrants, commitments, subscriptions, rights to
  purchase or otherwise), pledge or otherwise encumber any shares of its
  capital stock or the capital stock of any of its subsidiaries, any other
  voting securities or any securities convertible into, or any rights,
  warrants or options to acquire, any such shares, voting securities or
  convertible securities or any other securities or equity equivalents
  (including without limitation stock appreciation rights);
 
    (vii) except as contemplated by this Agreement, amend its Restated
  Articles of Incorporation, By-Laws or equivalent organizational documents;
 
    (viii) make or agree to make any acquisition of assets which is material
  to Ophthalmic except for purchases of inventory, supplies and material in
  the ordinary course of business;
 
    (ix) settle, pay or compromise any claims, individually or in the
  aggregate in an amount in excess of $100,000 (other than repayment of
  Ophthalmic's indebtedness to Imperial Bank), other than in consultation and
  cooperation with Premier, and, with respect to any such settlement, with
  the prior written consent of Premier, which consent shall not be
  unreasonably withheld;
 
    (x) make any material Tax election or settle or compromise any material
  Tax liability (whether with respect to amount or timing); or
 
    (xi) except in the ordinary course of business, modify, amend or
  terminate any material contract or waive or release or assign any material
  rights or claims.
 
  SECTION 6.2 Covenants of Premier. From the date of this Agreement until the
earliest of (a) August 30, 1998, (b) the termination of this Agreement, and
(c) the closing of the Proposed Merger, Premier covenants and agrees that it
shall (x) continue to conduct its business and the business of its
Subsidiaries in a manner designed in its reasonable judgment, to enhance the
long-term value of the Premier Common Stock and the business prospects of
Premier and its Subsidiaries, and (y) take no action which would (i)
materially adversely affect the ability of any party to this Agreement to
obtain any consents, approvals, or authorizations required for the
transactions contemplated hereby without imposition of a condition or
restriction of any materially adverse conditions or restrictions, or (ii)
materially adversely affect the ability of any party to perform its covenants
and agreements under this Agreement; provided, that the foregoing shall not
prevent Premier from discontinuing or disposing of any of its properties,
assets, or business if such action is, in the judgment of Premier, desirable
in the conduct of the business of Premier and its Subsidiaries.
 
                                      14

 
  SECTION 6.3 Access to Information; Confidentiality. From the date hereof
until the earlier of the Expiration Date or the termination of this Agreement,
upon reasonable notice and subject to applicable laws, Premier and Ophthalmic
shall afford each other, and each other's accountants, counsel, and other
representatives, during normal business hours during the period of time prior
to the Expiration Date, reasonable access to all of its properties, books,
contracts, commitments, and records and, during such period, each of Premier
and Ophthalmic shall furnish promptly to the other (a) a copy of each report,
schedule, and other document filed or received by it during such period
pursuant to the requirements of federal and state securities laws, (b) a copy
of all filings made with any Governmental Entities in connection with the
transactions contemplated by this Agreement and all written communications
received from such Governmental Entities related thereto, and (c) all other
information concerning its business, properties, and personnel as such other
party may reasonably request. Each party hereto shall, and shall cause its
advisors and representatives to (x) conduct its investigation in such a manner
that will not unreasonably interfere with the normal operations, customers or
employee relations of the other and shall be in accordance with procedures
established by the parties having due regard for the foregoing, and (y)
refrain from using for any purposes other than as set forth in this Agreement
and shall treat as confidential all such information obtained by each
hereunder or in connection herewith and not otherwise known to them prior to
the Expiration Date. Except as otherwise agreed to in writing by Ophthalmic,
until the Expiration Date, Premier and its Subsidiaries and affiliates will be
bound by, and all information received with respect to Ophthalmic pursuant to
this Section 6.3 shall be subject to that certain confidentiality agreement
entered into with Premier on February 12, 1998 (the "Ophthalmic
Confidentiality Agreement"). Except as otherwise agreed to in writing by
Premier, until the Expiration Date, Ophthalmic will be bound by, and all
information received with respect to Premier pursuant to this Section 6.3
shall be subject to that certain Confidentiality Agreement entered into with
Ophthalmic on February 20, 1998 (the "Premier Confidentiality Agreement").
 
  SECTION 6.4 Efforts.
 
  (a) Upon the terms and subject to the conditions set forth in this
Agreement, each of the parties hereto agrees to use its reasonable best
efforts to take, or cause to be taken, all appropriate action, and to do, or
cause to be done, all things necessary, proper or advisable to consummate and
make effective the transactions contemplated by this Agreement, including (i)
obtaining all necessary opinions, waivers, consents and approvals and effect
all necessary registrations and filings and (ii) defending any lawsuit or
other legal proceedings challenging this Agreement or the Offer. In case at
any time after the Expiration Date any further action is necessary or
desirable to carry out the purposes of this Agreement, the proper officers and
directors of each party to this Agreement shall take all such necessary
action. Without limiting the foregoing, each of Ophthalmic and Premier shall
make all necessary filings with Governmental Entities as promptly as
practicable in order to facilitate prompt consummation of the transactions
contemplated by the Offer and this Agreement. In addition, each of Premier and
Ophthalmic will use its reasonable best efforts (including, without
limitation, exchange of any required fees) and will cooperate fully with each
other to (i) comply as promptly as practicable with all governmental
requirements applicable to the transactions contemplated by the Offer and this
Agreement, including the making of all filings necessary or proper under
applicable laws and regulations to consummate and make effective the
transactions contemplated by the Offer and this Agreement, including, but not
limited to, cooperation in the preparation and filing of the Offer Documents,
the Schedule 14D-9 and any actions or filings related thereto, and any
amendments to any thereof, and (ii) obtain promptly all consents, waivers,
approvals, authorizations or permits of, or registrations or filings with or
notifications to (any of the foregoing being a "Consent"), any Governmental
Entity necessary for the consummation of the transactions contemplated by the
Offer and this Agreement. Premier and Ophthalmic shall furnish to each other
such necessary information and reasonable assistance as Premier or Ophthalmic
may reasonably request in connection with the foregoing. In addition, if at
any time prior to the Expiration Date any event or circumstance relating to
either Ophthalmic or Premier or any of their respective subsidiaries, should
be discovered by Ophthalmic or Premier, as the case may be, and which should
be set forth in an amendment to the Offer Documents or Schedule 14D-9, the
discovering party will promptly inform the other party of such event or
circumstance.
 
  (b) Without limiting Section 6.4(a), Premier and Ophthalmic shall each (i)
take any and all steps necessary to avoid or eliminate each and every
impediment under any antitrust, competition, or trade regulation law that
 
                                      15

 
may be asserted by any Governmental Entity with respect to the Offer so as to
enable consummation thereof to occur as soon as reasonably possible, including
without limitation, proposing, negotiating, committing to and effecting, by
consent decree, hold separate order, or otherwise, the sale, divestiture or
disposition of such assets or businesses of Premier or Ophthalmic as may be
required in order to avoid the entry of, or to effect the dissolution of, any
injunction, temporary restraining order or other order in any suit or
proceeding, which would otherwise have the effect of preventing or delaying
consummation of the Offer or the Proposed Merger; and (ii) use its reasonable
best efforts to avoid the entry of, or to have vacated or terminated, any
decree, order, or judgment that would restrain, prevent or delay the
consummation of the Offer, including without limitation defending through
litigation on the merits any claim asserted in any court by any party. Each
party hereto shall promptly notify the other parties of any written
communication to that party from any Governmental Entity and permit the other
parties to review in advance any proposed communication to any Governmental
Entity. Premier and Ophthalmic shall not (and shall cause their respective
affiliates and representatives not to) agree to participate in any meeting
with any Governmental Entity in respect of any filings, investigation or other
inquiry unless it consults with the other party in advance and, to the extent
permitted by such Governmental Entity, gives the other party the opportunity
to attend and participate thereat. Each of the parties hereto will coordinate
and cooperate fully with the other parties hereto in exchanging such
information and providing such assistance as such other parties may reasonably
request in connection with the foregoing.
 
  SECTION 6.5 Public Announcements. From the date of this Agreement, until the
Expiration Date or the termination of this Agreement, each of Ophthalmic and
Premier agree to consult promptly with each other prior to issuing any press
release or otherwise making any public statement with respect to the Offer,
the Proposed Merger and the other transactions contemplated hereby, agree to
provide to the other party for review a copy of any such press release or
statement, and shall not issue any such press release or make any such public
statement prior to such consultation and review, unless required by applicable
law or any listing agreement with a securities exchange.
 
  SECTION 6.6 Employee Benefit Arrangements; Warrants. (a) Each of Ophthalmic
and Premier agrees that it will take all corporate action to amend or adopt
new stock options and/or stock incentive plans and warrants to provide for the
issuance of Premier Common Stock rather than Common Stock issuable upon
exercise of such plan or plans or warrants, effective as of the Expiration
Date as set forth below.
 
    (i) Vested Options. The value of outstanding, unexercised, vested
  Ophthalmic Options of a holder (the "Vested Options") shall be equal to the
  product of (x) $2.18 multiplied by (y) the number of shares of Common Stock
  issuable upon exercise thereof (the "Aggregate Ophthalmic Option Value").
  On the Expiration Date, each Vested Option of a holder shall be exchanged
  for Premier options (the "Premier Options") issuable for that number of
  shares of Premier Common Stock (the "Vested Exchange Rate") equal to (xx)
  the Aggregate Ophthalmic Option Value of a holder divided by (yy) the
  Premier Average Price. The exercise price per share of Premier Common Stock
  issuable to a holder upon exercise of the Premier Options (the "Vested
  Exercise Price") shall be equal to (xxx) the aggregate exercise price for
  all Vested Options exchanged by such holder divided by (yyy) the number of
  shares of Premier Common Stock issuable to such holder upon exercise of the
  Premier Options exchanged therefor. Ophthalmic Options granted under
  Ophthalmic's 1997 Stock Option Plan shall vest on the Expiration Date and
  shall be Vested Options.
 
    (ii) Unvested Options. Unless earlier terminated, each outstanding,
  unexercised, unvested Ophthalmic Option shall vest (a "Subsequently Vesting
  Option") on the earlier of (aa) its scheduled vesting date and (bb) with
  respect to any Ophthalmic employee who is employed by Ophthalmic, Premier
  or any of their affiliates six (6) months after the Expiration Date, six
  (6) months following the Expiration Date (the "Measurement Date"). On the
  Measurement Date, the Subsequently Vesting Option of a holder shall be
  exchanged for Premier Options issuable for that number of shares of Premier
  Common Stock equal to (xx) the Aggregate Ophthalmic Option Value of a
  holder attributable to such Subsequently Vesting Options divided by (yy)
  the Premier Average Price calculated using the Measurement Date in lieu of
  the Expiration Date. The exercise price per share of Premier Common Stock
  issuable to a holder upon exercise of such
 
                                      16

 
  Subsequently Vesting Options shall be equal to (xxx) the aggregate exercise
  price for all Subsequently Vesting Options of such holder that vested on
  such Measurement Date divided by (yyy) the number of shares of Premier
  Common Stock issuable upon exercise of the Premier Options exchanged
  therefor. Ophthalmic Options not granted under Ophthalmic's 1997 Stock
  Option Plan shall vest as provided in this Section 6.1(a)(ii).
 
    (iii) Exchange and Pricing Election. Notwithstanding anything to the
  contrary contained in Section 6.6(a)(ii), each holder of Ophthalmic Options
  not granted under Ophthalmic's 1997 Stock Option Plan may elect, by
  providing written notice to Ophthalmic prior to the Expiration Date, to
  have such holder's Ophthalmic Options exchanged, when vested as provided in
  Section 6.6(a)(ii), for Premier Options at the Vested Exchange Rate for an
  exercise price equal to the Vested Exercise Price.
 
    (iv) Termination of Employment. For a period of six (6) months following
  the Expiration Date, Ophthalmic Options issued to officers or employees of
  Ophthalmic, which have not earlier vested as provided herein, shall vest on
  the date of termination of such officer or employee "without cause" by
  Ophthalmic or Premier, as determined in the reasonable discretion of
  Ophthalmic, in which case such Ophthalmic Options shall be exchanged in
  accordance with Section 6.6(a)(ii) (with the date of such termination being
  the Measurement Date), or Section 6.6(a)(i) if a valid election is made by
  such officer or employee pursuant to Section 6.6(a)(iii).
 
  (b) Following the Expiration Date, Premier shall provide or cause its
Subsidiaries to provide generally to officers and employees of Ophthalmic
employee benefits, including without limitation, pension benefits, health and
welfare benefits, life insurance and vacation, and severance arrangements, on
terms and conditions which when taken as a whole are no less favorable than
those currently provided by Premier and its Subsidiaries to their similarly
situated officers and employees. Premier does not currently provide its
officers and employees with pension benefits or severance plans. For purposes
of participation and vesting under any employee benefit plan of Ophthalmic and
its Subsidiaries, the service of the employees of Ophthalmic prior to the
Expiration Date shall be treated as service with the Premier or its
subsidiaries participating in such employee benefit plans. Premier shall, and
shall cause its Subsidiaries to, honor in accordance with their terms, all
Employment Contracts, and all provisions for vested benefits or other vested
amounts earned or accrued through the Expiration Date under the Plans.
 
  (c) For a period of ninety (90) days following the Expiration Date, Premier
shall provide or cause its Subsidiaries to provide generally to officers and
employees of Ophthalmic severance benefits equal to one week's pay for each
full year of service to Ophthalmic to each such officer or employee that is
terminated without cause by Premier or its Subsidiary. The phrase "without
cause" shall not apply to those officers and employees that are terminated
because they do not elect to work for Premier or its Subsidiaries.
 
  SECTION 6.7 Notification of Certain Matters. Premier and Ophthalmic shall
promptly notify each other orally and in writing of (i) the occurrence or non-
occurrence of any fact or event which would be reasonably likely (A) to cause
any representation or warranty contained in this Agreement to be untrue or
inaccurate in any material respect at any time from the date hereof to the
Expiration Date or (B) to cause any covenant, condition or agreement under
this Agreement not to be complied with or satisfied in any material respect
and (ii) any failure of Ophthalmic or Premier, as the case may be, to comply
with or satisfy any covenant, condition or agreement to be complied with or
satisfied by it hereunder; provided, however, that no such notification shall
affect the representations or warranties of any party or the conditions to the
obligations of any party hereunder. Each of Ophthalmic and Premier shall give
prompt notice to the other of any notice or other communication from any third
party alleging that the consent of such third party is or may be required in
connection with the transactions contemplated by this Agreement.
 
  SECTION 6.8 Rights Agreement. Ophthalmic covenants and agrees that, unless
the Board of Directors of Ophthalmic determines in good faith by a majority
vote that taking such action is necessary in the exercise of its fiduciary
obligations under applicable law, it will not (i) redeem the Rights, (ii)
amend the Rights Agreement except as provided in Section 4.16, or (iii) take
any action which would allow any Person (as defined in the
 
                                      17

 
Rights Agreement) other than Premier to acquire beneficial ownership of 20% or
more of the Common Stock without causing a Distribution Date (as such term is
defined in the Rights Agreement) to occur.
 
  SECTION 6.9 State Takeover Laws. Ophthalmic covenants and agrees that,
unless the Board of Directors of Ophthalmic determines in good faith by a
majority vote that taking such action is proscribed in the exercise of its
fiduciary obligations under applicable law, it shall, upon the request of
Premier, take all reasonable steps to assist in any challenge by Premier to
the validity or applicability to the transactions contemplated by this
Agreement, including the Offer and the Proposed Merger, of any state takeover
law.
 
  SECTION 6.10 No Solicitation.
 
  (a) Ophthalmic represents and warrants to, and covenants and agrees with,
Premier that Ophthalmic does not have any agreement, arrangement or
understanding with any potential third party acquiror that, directly or
indirectly, would be violated, or require any exchanges, by reason of the
execution, delivery and/or consummation of this Agreement. Ophthalmic shall,
and it shall cause its officers, directors, employees, investment bankers,
attorneys and other agents and representatives to, immediately cease any
existing discussions or negotiations with any person other than Premier (a
"Third Party") heretofore conducted with respect to any Acquisition
Transaction (as hereinafter defined). Ophthalmic shall not, and it shall
prohibit its officers, directors, employees, investment bankers, attorneys and
other agents and representatives from taking any action to, directly or
indirectly, (w) solicit, initiate, continue, facilitate or encourage
(including by way of furnishing or disclosing non-public information) any
inquiries, proposals or offers from any Third Party with respect to any
acquisition or purchase of a material portion of the assets (other than in the
ordinary course of business) or business of, or any significant equity
interest in (including by way of a tender offer), or any merger, consolidation
or business combination with, or any recapitalization or restructuring, or any
similar transaction involving, Ophthalmic (the foregoing being referred to
collectively as an "Acquisition Transaction"), or (x) negotiate, explore or
otherwise communicate in any way with any Third Party with respect to any
Acquisition Transaction, (y) enter into, approve or recommend any agreement,
arrangement or understanding requiring Ophthalmic to abandon, terminate or
fail to recommend that its stockholders accept the Offer or any other
transaction contemplated hereby, or (z) withdraw or modify, or propose
publicly to withdraw or modify, in a manner adverse to Premier, the approval
or recommendation by the Ophthalmic Board of the Offer, or this Agreement;
provided, however, that nothing herein shall prevent the Ophthalmic Board from
taking, and disclosing to Ophthalmic's shareholders, a position contemplated
by Rules 14d-9 and 14e-2 promulgated under the Exchange Act with respect to
any tender offer. Ophthalmic will promptly notify Premier of the receipt of
any proposal relating to an Acquisition Transaction. Notwithstanding anything
to the contrary in the foregoing, Ophthalmic may, in response to an
unsolicited written proposal with respect to an Acquisition Transaction
involving an Acquisition Transaction from a Third Party (i) furnish or
disclose non-public information to such Third Party and (ii) negotiate,
explore or otherwise communicate with such Third Party, in each case only if
(a) after being advised (x) by its outside counsel with respect to its
fiduciary obligations and (y) with respect to the financial terms of any such
proposed Acquisition Transaction, the Board of Directors of Ophthalmic
determines in good faith by a majority vote that taking such action is
necessary in the exercise of its fiduciary obligations under applicable law
(the proposal with respect to an Acquisition Transaction meeting the
requirements of this clause (a), a "Superior Proposal") and (b) prior to
furnishing or disclosing any non-public information to, or entering into
discussions or negotiations with, such Third Party, Ophthalmic receives from
such Third Party an executed confidentiality agreement (which Ophthalmic is
hereby expressly permitted to negotiate with such party) with terms no less
favorable in the aggregate to Ophthalmic than those contained in the
Ophthalmic Confidentiality Agreement, but which confidentiality agreement
shall not provide for any exclusive right to negotiate with Ophthalmic or any
exchanges by Ophthalmic and need not contain any "standstill" or similar
provisions. In addition, the Ophthalmic Board may approve or recommend (and,
in connection therewith withdraw or modify its approval or recommendation of
the Offer or this Agreement) a Superior Proposal and may terminate this
Agreement solely to enter into a definitive agreement with respect to a
Superior Proposal provided, however, that Ophthalmic shall not, and shall
cause its affiliates not to, enter into a definitive agreement with respect to
a Superior Proposal unless Ophthalmic concurrently terminates this Agreement
in accordance with the terms hereof and pays any Termination Fee required
under Section 8.3(b).
 
                                      18

 
  (b) Ophthalmic shall promptly (but in any event within one business day of
Ophthalmic becoming aware of same) advise Premier of the receipt by
Ophthalmic, any of its subsidiaries or any of Ophthalmic's bankers, attorneys
or other agents or representatives of any written inquiries or proposals
relating to an Acquisition Transaction and any actions taken pursuant to
Section 6.9(a), and shall promptly (but in any event within one business day
of Ophthalmic becoming aware of same) provide Premier with a copy of any such
written inquiry or proposal. Ophthalmic shall keep Premier reasonably informed
of the status and content of and material developments (including the calling
of meetings of the Ophthalmic Board to take action with respect to such
Acquisition Transaction) with respect to any discussions regarding any
Acquisition Transaction with a Third Party. Ophthalmic agrees that it will not
enter into any agreement with respect to a Superior Proposal unless and until
Premier has been given notice of the identity of the parties making such
Superior Proposal, the material terms thereof and material developments
referred to in the preceding sentence at least two business days prior to the
entering into such agreement.
 
  SECTION 6.11 Indemnification.
 
  (a) Premier shall, and in the event of a Proposed Merger, shall cause the
surviving corporation of the Proposed Merger (and its successors and assigns)
to, indemnify, defend, and hold harmless the present directors, officers,
employees, and agents of Ophthalmic (each, an "Indemnified Party") after the
Expiration Date against all costs, fees, or expenses (including reasonable
attorneys' fees) judgments, fines, penalties, losses, damages, liabilities,
and amounts paid in settlement in connection with any claim, action, suit,
proceeding, or investigation, whether civil, administrative, or investigative,
arising out of actions or omissions occurring at or prior to the Expiration
Date (including the transactions contemplated by this Agreement), unless such
actions or omissions constitute fraud or willful misconduct, to the full
extent permitted under California law and by Ophthalmic's Restated Articles of
Incorporation and By-Laws as in the effect as of the date hereof, including
any provisions relating to advances of expenses incurred in the defense of any
action, suit, or proceeding for a period of five years after the date hereof.
If indemnification is sought hereunder, the Indemnified Party shall notify
Premier of the commencement of the litigation, proceeding, or other action, or
any overt threat with respect to any of the foregoing; provided, however, that
the failure to provide such notification shall not relieve Premier from its
indemnification obligations hereunder or otherwise to such Indemnified Party
unless and only to the extent that such failure shall materially and adversely
affect the ability of Premier to defend such litigation, proceeding, or other
action. Following such notification, Premier may elect to assume the defense
of such litigation, proceeding, or other action (and the costs related
thereto) and, upon such defense of such election, Premier shall not be liable
for any legal costs subsequently incurred by such Indemnified Party (other
than the costs of investigation or the production of documents or witnesses)
unless (i) Premier fails to provide legal counsel reasonably satisfactory to
such Indemnified Party in a timely manner, or (ii) such Indemnified Party
shall have reasonably concluded that (A) the representation of such
Indemnified Party by legal counsel selected by Premier would be inappropriate
due to actual or potential conflicts of interest or (B) there may be a legal
defense available to such Indemnified Party that are different from or
additional to those available to the Premier or any other Indemnified Party
represented by such legal counsel. Nothing set forth herein shall preclude any
Indemnified Party from retaining its own counsel at its own expense. Premier
shall, and shall cause the surviving corporation of any Proposed Merger and
all other relevant Premier Subsidiaries to apply such rights of
indemnification in good faith and to the fullest extent permitted by
applicable law.
 
  (b) Incident to any information furnished or disclosed by Premier or any
Premier Subsidiary in connection with the Offer Documents and the Schedule
14D-9, and subject to applicable law, Premier shall indemnify, defend, and
hold harmless Indemnified Parties against all costs, fees, or expenses
(including reasonable attorneys' fees), judgments, fines, penalties, losses,
damages, liabilities, and amounts paid in settlement in connection with any
claim, action, suit, proceeding, or investigation, whether civil,
administrative, or investigative, arising out of or under the securities laws
or any state blue sky or securities laws based in whole or in part on (i) any
untrue statement or alleged untrue statement of a material fact contained in
such documents including any amendment or supplement to such document, (ii)
any omission or alleged omission to state in such documents a material fact
required to be stated therein or necessary to make the statements therein not
misleading, or (iii) any violation of
 
                                      19

 
Premier or any Premier Subsidiary of the securities laws or any state blue sky
or securities laws in connection with such documents; provided, however, that
neither Premier or any Premier Subsidiary will be liable in any such case to
the extent that any such claim, action, suit, or investigation is based on any
untrue statement or alleged untrue statement or omission or alleged omission
made in such Offer Document or Schedule 14D-9 or any amendment or supplement
thereto in reliance upon and in conformity with information furnished in
writing to Premier or any Premier Subsidiary by Ophthalmic or any Indemnified
Party specifically for use therein.
 
  (c) If Premier or the surviving corporation in any Proposed Merger or any of
its successors or assigns shall consolidate with or merge into any other
corporation or entity and shall not be the continuing or surviving corporation
or entity of such consolidation or merger or shall transfer all or
substantially all of its assets to any person, corporation or entity, then in
each case, proper provision shall be made so that the successors and assigns
of Premier shall assume the obligations set forth in this Section 6.11.
 
  (d) For five years from the Expiration Date, Premier shall use its best
efforts to maintain in effect, if available, directors' and officers'
insurance liability in an amount equal to $2,000,000, covering those persons
who are currently covered by the directors' and officers' liability insurance
policy maintained by Ophthalmic.
 
  (e) The provisions of this Section 6.11 are intended to be for the benefit
of and shall be enforceable by, each Indemnified Party, his or her heirs and
representatives, and shall survive the consummation of the Offer and be
binding on all successors and assigns of Premier and the surviving corporation
of any Proposed Merger.
 
  SECTION 6.12 Conditions. Prior to consummating the exchange pursuant to the
Offer, Premier shall use its best efforts to (a) cause the Premier Common
Stock and the Premier Common Stock issuable upon exercise of the Warrants to
be listed on NASDAQ, (b) cause the Form S-4 to have been declared effective by
the Commission, and (c) deposit the Offer Consideration with the Exchange
Agent.
 
                                  ARTICLE VII
 
              CONDITIONS TO CONSUMMATE THE TRANSACTIONS HEREUNDER
 
  SECTION 7.1 Conditions. The respective obligations of each of Premier and
Ophthalmic to consummate the transactions contemplated hereby are subject to
the satisfaction, at or before the time each action is to be taken, of the
condition that no statute, rule, regulation, executive order, decree or
injunction shall have been enacted, entered, promulgated or enforced by any
court of competent jurisdiction or other Governmental Entity which prohibits
the consummation of the Offer or any other transactions contemplated hereunder
provided, however, that Ophthalmic and Premier shall use their reasonable best
efforts to have any such order, decree, or injunction vacated.
 
  SECTION 7.2 Conditions to Obligations of Premier. In the event the Offer
shall not have been terminated, the obligations of Premier to make the Offer
and to consummate the exchange pursuant to the Offer shall be further subject
to the following conditions:
 
  (a) Performance of Obligations of Ophthalmic. Ophthalmic shall have
performed the obligations required to be performed by it under Section 4.16.
 
  (b) Private Acquisition. The Private Acquisition shall have been
consummated.
 
  SECTION 7.3 Conditions of Premier to Close the Offer. Prior to consummating
the exchange pursuant to the Offer, Premier shall have (a) caused the Premier
Common Stock, the Premier Common Stock issuable upon exercise of the Warrants
and the Warrants to be listed on NASDAQ, (b) caused the Form S-4 to have been
declared effective by the Commission, and (c) deposited the Offer
Consideration with the Exchange Agent.
 
                                      20

 
                                 ARTICLE VIII
 
                        TERMINATION; AMENDMENTS; WAIVER
 
  SECTION 8.1 Termination. This Agreement shall be terminated if the Offer
shall not have been consummated by August 21, 1998, if each party has used its
best efforts to consummate the transaction, and may be terminated:
 
  (a) by the mutual written consent of Premier and Ophthalmic, by action of
their respective Boards of Directors;
 
  (b) by Ophthalmic, if Ophthalmic is not in material breach of any of its
representations contained in this Agreement and if (i) Premier fails to
commence the Offer as provided in Section 1.1, or (ii) at any time following
the Expiration Date, as it may be extended pursuant to Section 1.1(c), Premier
shall not have accepted for exchange and exchanged the Offer Consideration for
all Shares tendered pursuant to the Offer in accordance with the terms hereof
and thereof, or (iii) if Premier should withdraw, abandon, or terminate the
Offer without purchasing all Shares validly tendered pursuant to the Offer;
provided that all conditions to the Offer shall have been satisfied or waived
in accordance with the terms hereof;
 
  (c) by either Premier or Ophthalmic, if any court of competent jurisdiction
in the United States or other United States Governmental Entity has issued an
order, decree or ruling or taken any other action restraining, enjoining or
otherwise prohibiting the Offer and such order, decree, ruling or other action
shall have become final and nonappealable; provided, however, that the party
seeking to terminate this Agreement shall have used its reasonable best
efforts to remove or lift such order, decree, ruling or other action;
 
  (d) by Ophthalmic if, prior to the acceptance for exchange of Common Stock
pursuant to the Offer, (i) there shall have occurred, on the part of Premier,
a material breach of any representation or warranty, covenant or agreement
contained in this Agreement which is not curable or (ii) Ophthalmic (A) to the
extent permitted by Section 6.10, enters into a definitive agreement with
respect to a Superior Proposal and (B) concurrently pays any Termination Fee
required under Section 8.3(b); or
 
  (e) by Premier, prior to the exchange for Common Stock pursuant to the
Offer, if the Ophthalmic Board shall have withdrawn or modified (including by
amendment of the Schedule 14D-9) in a manner adverse to Premier its approval
or recommendation of the Offer or, this Agreement shall have approved or
recommended Superior Proposal, or shall have resolved to effect any of the
foregoing.
 
  SECTION 8.2 Effect of Termination. In the event of the termination of this
Agreement pursuant to Section 8.1, this Agreement shall forthwith become void
and have no effect, without any liability on the part of any party or its
directors, officers or stockholders, other than the provisions in Sections
8.2, 8.3, 9.2, 9.3, 9.5, 9.6, 9.10 and 9.11, and the last sentence in Section
6.3, which shall survive any such termination. Nothing contained in this
Section 8.2 shall relieve any party from liability for any breach of this
Agreement.
 
  SECTION 8.3 Fees and Expenses.
 
  (a) Except as otherwise specifically provided herein, all costs and expenses
incurred in connection with the Offer, this Agreement and the transactions
contemplated by this Agreement shall be paid by the party incurring such
expenses.
 
  (b) In the event that this Agreement is terminated as a result of a material
breach by Ophthalmic, then Ophthalmic shall promptly pay to Premier in lieu of
any other right to damages, a termination fee of $500,000. Thereafter,
Ophthalmic shall promptly pay to Premier an additional $250,000 (collectively,
the "Termination Fee") if Ophthalmic enters into a definitive agreement with
respect to a Superior Proposal within six (6) months of the date of
termination. For purposes of this Section 8.3, a "material breach by
Ophthalmic" shall include any action by Ophthalmic, its officers, directors,
employees, investment bankers, attorneys and other agents and representatives
(i) to redeem the Rights, (ii) to amend, terminate or waive rights under the
Rights Agreement (other than the Rights Agreement Amendment), (iii) to
solicit, initiate, continue, facilitate or encourage
 
                                      21

 
(including by way of furnishing or disclosing non-public information) any
Acquisition Transaction, (iv) to negotiate, explore or otherwise communicate
in any way with any Third Party with respect to any Acquisition Transaction,
(v) enter into, approve or recommend any agreement, arrangement or
understanding requiring Ophthalmic to abandon, terminate or fail to recommend
that its stockholders accept the Offer or any other transaction contemplated
hereby, or (vi) withdraw or modify (including by Amendment of the Schedule
14D-9), or propose publicly to withdraw or modify, in a manner adverse to
Premier, the approval or recommendation by the Ophthalmic Board of the Offer
or this Agreement.
 
  (c) In the event that this Agreement is terminated as a result of a material
breach by Premier, then Premier shall promptly pay to Ophthalmic in lieu of
any other right to damages, a termination fee of $500,000. For purposes of
this Section 8.3, a "material breach by Premier" shall include any action by
Premier to withdraw the Offer unless (i) following good faith efforts by
Premier, all of the conditions set forth in Annex I have not been satisfied,
or (ii) a material breach by Ophthalmic has occurred.
 
  SECTION 8.4 Amendment. This Agreement may not be amended except by an
instrument in writing signed on behalf of all the parties.
 
  SECTION 8.5 Extension; Waiver. Subject to Section 1.3(c), at any time
Premier and Ophthalmic may (i) extend the time for the performance of any of
the obligations or other acts of the other, (ii) waive any inaccuracies in the
representations and warranties contained herein of the other or in any
document, certificate or writing delivered pursuant hereto by the other, or
(iii) waive compliance by the other with any of the agreements or conditions.
Any agreement on the part of any party to any such extension or waiver shall
be valid only if set forth in an instrument in writing signed on behalf of
such party.
 
                                  ARTICLE IX
 
                                 MISCELLANEOUS
 
  SECTION 9.1 Non-Survival of Representations and Warranties. The
representations and warranties made in this Agreement shall not survive beyond
the Expiration Date. Notwithstanding the foregoing, the agreements set forth
in Sections 6.5, 8.3(a), 9.1 and 9.2 shall, and if the Offer closes, Sections
5.4, 5.5 and 6.6, shall, survive indefinitely. If the Offer closes, Section
6.11 shall survive until the expiration of the applicable statute of
limitations period. The agreements set forth in Section 9.3 shall survive as
provided therein.
 
  SECTION 9.2 General Release of Ophthalmic Executive Officers and Directors.
 
  (a) Premier and Ophthalmic hereby release the present officers and directors
of Ophthalmic (each, a "Releasee"), of and from all actions, causes of action,
suits, demands and all other claims whatsoever which Premier and/or Ophthalmic
ever had, now has, or which Premier or Ophthalmic hereafter can, shall or may
have against any Releasee in connection with such Releasee's role as officer
or director of Ophthalmic, arising out of actions or omissions occurring on or
prior to the date of this Agreement, unless such actions or omissions
constitute self-dealing, fraud or willful misconduct.
 
  (b) Premier and Ophthalmic hereby waive any rights they may have under
Section 1542 of the California Civil Code, which reads:
 
    "A general release does not extend to claims which the creditor does
    not know or suspect to exist in his favor at the time of executing the
    release, which if known by him must have materially affected his
    settlement with the debtor."
 
  SECTION 9.3 Entire Agreement; Assignment.
 
  (a) This Agreement (including the documents and the instruments referred to
herein) constitutes the entire agreement and supersedes all prior agreements
and understandings, both written and oral, among the parties with
 
                                      22

 
respect to the subject matter hereof and thereof, except for the Ophthalmic
Confidentiality Agreement, the Premier Confidentiality Agreement and
provisions of that certain standstill agreement entered into by and between
Premier and Ophthalmic in February 1998 (the "Standstill Agreement"), which
continue in effect. The Termination Date (as provided in the Standstill
Agreement) is hereby extended to that date which ends two (2) months following
the earlier of (i) the termination of this Agreement and (ii) the Expiration
Date if Premier shall not have accepted for exchange and exchanged the Offer
Consideration for all Shares tendered pursuant to the Offer in accordance with
terms hereof and thereof.
 
  (b) Neither this Agreement nor any of the rights, interests or obligations
hereunder will be assigned by any of the parties hereto (whether by operation
of law or otherwise) without the prior written consent of the other party
(except that Premier may assign its rights, interest and obligations to any
affiliate or direct or indirect subsidiary of Premier without the consent of
Ophthalmic provided that no such assignment shall relieve Premier of any
liability for any breach by such assignee). Subject to the preceding sentence,
this Agreement will be binding upon, inure to the benefit of and be
enforceable by the parties and their respective successors and assigns.
 
  SECTION 9.4 Validity. The invalidity or unenforceability of any provision of
this Agreement shall not affect the validity or enforceability of any other
provision of this Agreement, each of which shall remain in full force and
effect.
 
  SECTION 9.5 Notices. All notices, requests, claims, demands and other
communications hereunder shall be in writing and shall be deemed to have been
duly given when delivered in person, by overnight courier or telecopier to the
respective parties as follows:
 
  If to Premier:
 
  Premier Laser Systems, Inc.
  3 Morgan
  Irvine, California 92718
  Attention: President and Chief Executive Officer
  Facsimile Number: (714) 952-7218
 
  with a copy to:
 
  Paul, Hastings, Janofsky & Walker LLP
  695 Town Center Drive
  17th Floor
  Costa Mesa, California 92626
  Attn: William J. Simpson, Esq.
  Facsimile Number: (714) 979-1921
 
  If to Ophthalmic:
 
  Ophthalmic Imaging Systems
  221 Lathrop Way, Suite I
  Sacramento, California 95815
  Attn: President
  Facsimile Number: (916) 646-0207
 
  with a copy to:
 
  Carlton Fields, Attorneys at Law
  One Harbour Place
  777 S. Harbour Island Boulevard
  Tampa, Florida 33602-5799
  Attention: Richard A. Denmon, Esq.
  Facsimile Number: (813) 229-4133
 
                                      23

 
or to such other address as the person to whom notice is given may have
previously furnished to the other in writing in the manner set forth above;
provided that notice of any change of address shall be effective only upon
receipt thereof.
 
  SECTION 9.6 Governing Law. This Agreement shall be governed by and construed
in accordance with the laws of the State of California, regardless of the laws
that might otherwise govern under applicable principles of conflicts of laws
thereof.
 
  SECTION 9.7 Descriptive Headings. The descriptive headings herein are
inserted for convenience of reference only and are not intended to be part of
or to affect the meaning or interpretation of this Agreement.
 
  SECTION 9.8 Counterparts. This Agreement may be executed in two or more
counterparts, each of which shall be deemed to be an original, but all of
which shall constitute one and the same agreement.
 
  SECTION 9.9 Parties in Interest. This Agreement, except for Sections 6.6,
6.11 and 9.2, shall be binding upon and inure solely to the benefit of each
party hereto, and nothing in this Agreement, express or implied, is intended
to confer upon any other person any rights or remedies of any nature
whatsoever under or by reason of this Agreement.
 
  SECTION 9.10 Certain Definitions. As used in this Agreement:
 
  (a) the term "affiliate," as applied to any person, shall mean any other
person directly or indirectly controlling, controlled by, or under common
control with, that person. For the purposes of this definition, "control"
(including, with correlative meanings, the terms "controlling," "controlled
by" and "under common control with"), as applied to any person, means the
possession, directly or indirectly, of the power to direct or cause the
direction of the management and policies of that person, whether through the
ownership of voting securities, by contract or otherwise;
 
  (b) the term "Person" or "person" shall include individuals, corporations,
partnerships, trusts, other entities and groups (which term shall include a
"group" as such term is defined in Section 13(d)(3) of the Exchange Act); and
 
  (c) the term "Subsidiary" or "subsidiaries" means, with respect to Premier
or any other person, any corporation, partnership, joint venture or other
legal entity of which Premier, or such other person, as the case may be
(either alone or through or together with any other subsidiary), owns,
directly or indirectly, stock or other equity interests the holders of which
are generally entitled to more than 50% of the vote for the election of the
board of directors or other governing body of such corporation or other legal
entity.
 
  SECTION 9.11 Specific Performance. The parties hereto agree that irreparable
damage would occur in the event that any of the provisions of this Agreement
were not performed in accordance with their specific terms or were otherwise
breached. It is accordingly agreed that the parties shall be entitled to an
injunction or injunctions to prevent breaches of this Agreement and to enforce
specifically the terms and provisions hereof in any court of the United States
or any state having jurisdiction, this being in addition to any other remedy
to which they are entitled at law or in equity, except for termination fees
and expenses.
 
  SECTION 9.12 Fiduciary Duty. Notwithstanding anything to the contrary in
this Agreement, no provision of this Agreement shall be construed to prevent
the exercise by any director of Ophthalmic (or the actions of Ophthalmic
thereon) of his or her fiduciary duty as contemplated to be exercised under
Section 6.10 of this Agreement.
 
  SECTION 9.13 Obligation of Premier. Whenever this Agreement requires Premier
to take any action, such requirement shall be deemed to include an undertaking
by Premier to cause the Premier Subsidiaries to take such action.
 
                           [Signature page follows]
 
                                      24

 
                  [SIGNATURE PAGE--STOCK PURCHASE AGREEMENT]
 
  IN WITNESS WHEREOF, each of the parties has caused this Agreement to be
executed on its behalf by its respective officer thereunto duly authorized,
all as of the day and year first above written.
 
                                          PREMIER LASER SYSTEMS, INC.
 
                                                   /s/ Colette Cozean
                                          By: _________________________________
                                                   Colette Cozean, Ph.D.
                                                  Chief Executive Officer
 
                                          OPHTHALMIC IMAGING SYSTEMS
 
                                                  /s/ Steven Verdooner
                                          By: _________________________________
                                                      Steven Verdooner
                                                  Chief Executive Officer
 
                                      25

 
                                    ANNEX I
 
  Conditions to the Offer. Notwithstanding any other provisions of the Offer,
Premier shall not be required to accept for exchange or, subject to any
applicable rules and regulations of the SEC, including Rule 14e-1(c)
promulgated under the Exchange Act, exchange for any tendered Shares and may
terminate or amend the Offer, if (i) the Rights have not been redeemed or
invalidated or are otherwise inapplicable to the Offer, (ii) Premier does not
receive all applicable governmental and Nasdaq authorizations, consents,
orders and appraisals, including the continued effectiveness of its Form S-4
filed in connection with the transactions contemplated by the Agreement, (iii)
at any prior to the time of acceptance for exchange or exchange for any
Shares, any of the following events shall occur:
 
    (a) there shall have been instituted or be pending any action or
  proceeding before any court or governmental, administrative or regulatory
  authority or agency, domestic or foreign (each, a "Governmental Entity"),
  or by any other person, domestic or foreign, before any court or
  Governmental Entity, (i) challenging or seeking to, or which is reasonably
  likely to, make illegal, materially delay or otherwise directly or
  indirectly restrain or prohibit or seeking to, or which is reasonably
  likely to, impose voting, procedural, price or other requirements, in
  addition to those required by federal securities laws and the CGCL (each as
  in effect on the date of the Prospectus/Offer to Exchange is filed with the
  SEC in connection with the Offer), in connection with the making of the
  Offer, the acceptance for exchange of, or exchange for, any Shares by
  Premier or any other affiliate of Premier or other business combination
  with Ophthalmic, or seeking to obtain material damages in connection
  therewith; (ii) seeking to prohibit or limit materially the ownership or
  operation by Ophthalmic, Premier or any of their subsidiaries of all or any
  material portion of the business or assets of Ophthalmic, Premier or any of
  their subsidiaries, or to compel Ophthalmic, Premier or any of their
  subsidiaries to dispose of or hold separate all or any material portion of
  the business or assets of Ophthalmic, Premier or any of their subsidiaries;
  (iii) seeking to impose or confirm limitations on the ability of Premier or
  any other affiliate of Premier to exercise effectively full rights of
  ownership of any Shares (including the Rights associated with Shares),
  including, without limitation, the right to vote any Shares acquired by
  Premier pursuant to the Offer or otherwise on all matters properly
  presented to Ophthalmic's shareholders; (iv) seeking to require divestiture
  by Premier or any other affiliate of Premier of any Shares; (v) seeking any
  material diminution in the benefits expected to be derived by Premier, or
  any other affiliate of Premier as a result of the transactions contemplated
  by the Offer or any other similar business combination with Ophthalmic;
  (vi) otherwise directly or indirectly relating to the Offer or which
  otherwise, in the reasonable judgment of Premier and Ophthalmic, might
  materially adversely affect Ophthalmic or Premier, or any other affiliate
  of Premier; or (vii) which otherwise, in the reasonable judgment of Premier
  and Ophthalmic, is reasonably likely to materially adversely affect the
  business, operations (including, without limitation, results of
  operations), properties (including, without limitation, intangible
  properties), condition (financial or otherwise), assets or liabilities
  (including, without limitation, contingent liabilities) or prospects of
  either Ophthalmic or Premier;
 
    (b) there shall have been any action taken, or any statute, rule,
  regulation, legislation, interpretation, judgment, order or injunction
  enacted, entered, enforced, promulgated, amended, issued or deemed
  applicable to (i) Premier, Ophthalmic or any subsidiary or affiliate of
  Premier or (ii) the Offer or other business combination by Premier or any
  affiliate of Premier with Ophthalmic, by any legislative body, court,
  government or governmental, administrative or regulatory authority or
  agency, domestic or foreign, which, in the sole judgment of Premier, is
  reasonably likely to result, directly or indirectly, in any of the
  consequences referred to in clauses (i) through (vii) of paragraph (a)
  above;
 
    (c) there shall have occurred (i) any general suspension of, or
  limitation on prices for, trading in securities on Nasdaq, the New York
  Stock Exchange (NYSE) or any other securities exchange, (ii) any decline,
  measured from the close of business on February 25, 1998, in the Standard &
  Poor's 500 Index by an amount in excess of 20%, (iii) any material adverse
  change in United States currency exchange rates or a suspension of, or
  limitation on, currency exchange markets, (iv) a declaration of a banking
  moratorium or any suspension of payments in respect of banks in the United
  States, (v) any limitation (whether or not
 
                                      26

 
  mandatory) by any government or governmental, administrative or regulatory
  authority or agency, domestic or foreign, on, or other event that, in the
  sole judgment of Premier, might affect the extension of credit by banks or
  other lending institutions, (vi) a commencement of a war or armed
  hostilities or other national or international calamity directly or
  indirectly involving the United States or (vii) in the case of any of the
  foregoing existing on February 25, 1998, a material acceleration or
  worsening thereof;
 
    (d) Ophthalmic shall have, directly or indirectly, (i) split, combined or
  otherwise changed, or authorized or proposed a split, combination or other
  change of, the Shares or its capitalization, (ii) issued or sold, or
  authorized or proposed the issuance, distribution or sale of, additional
  Shares (other than the issuance of Shares under options and warrants
  outstanding prior to the date of this Offer to Exchange, in accordance with
  the terms of such options as such terms have been publicly disclosed prior
  to the date of this Offer to Exchange), shares of any other class of
  capital stock, other voting securities or any securities convertible into,
  or rights, warrants or options, conditional or otherwise, to acquire, any
  of the foregoing, (iii) declared or paid, or proposed to declare or pay,
  any dividend or other distribution, whether payable in cash, securities or
  other property, on or with respect to any shares of capital stock of
  Ophthalmic, (iv) altered or proposed to alter any material term of any
  outstanding security (including the Rights) other than to amend the Rights
  Agreement to make the Rights inapplicable to Premier, (v) authorized,
  recommended, proposed or entered into an agreement, agreement in principle
  or arrangement or understanding with respect to any merger, consolidation,
  liquidation, dissolution, business combination, acquisition of assets,
  disposition of assets, release or relinquishment of any material
  contractual or other right of Ophthalmic or any comparable event not in the
  ordinary course of business, (vi) authorized, recommended, proposed or
  entered into, or announced its intention to authorize, recommend, propose
  or enter into, any agreement, arrangement or understanding with any person
  or group that in the sole judgment of Premier could adversely affect either
  the value of Ophthalmic or any of its subsidiaries, joint ventures or
  partnerships or the value of the Shares to Premier or any affiliate of
  Premier, (vii) entered into or amended any employment, change in control,
  severance, executive compensation or similar agreement, arrangement or plan
  with or for the benefit of any of its employees, consultants or directors,
  or made grants or awards thereunder, other than in the ordinary course of
  business or entered into any agreements, arrangements or plans so as to
  provide for increased or accelerated benefits to any such persons, (viii)
  except as may be required by law, taken any action to terminate or amend
  any employee benefit plan (as defined in Section 3(3) of the Employee
  Retirement Income Security Act of 1974, as amended) of Ophthalmic or any of
  its subsidiaries, or Premier shall have become aware of any such action
  that was not disclosed in publicly available filings prior to the date of
  this Offer to Exchange, or (ix) except as contemplated by this Agreement
  amended or authorized or proposed any amendment to Ophthalmic's Restated
  Articles of Incorporation or Bylaws, or Premier shall have become aware
  that Ophthalmic shall have proposed or adopted any such amendment that was
  not disclosed in publicly available filings prior to the date of the
  Prospectus/Offer to Exchange;
 
    (e) any person or group shall have entered into a definitive agreement or
  an agreement in principle or made a proposal with respect to a tender offer
  or exchange offer or a merger, consolidation or other business combination
  with Ophthalmic;
 
    (f) any approval, permit, authorization or consent of any governmental
  authority or agency needed for the Offer shall not have been obtained on
  terms satisfactory to Premier or Premier shall have been notified by
  Ophthalmic that such terms are not satisfactory to Ophthalmic;
 
    (g) the Agreement shall have been terminated in accordance with its
  terms; or
 
    (h) Ophthalmic's Board of Directors shall have publicly withdrawn or
  modified in any manner adverse to Premier its recommendation that
  shareholders accept the Offer.
 
The foregoing conditions (including those set forth in clauses (i) and (ii) of
the initial paragraph) are for the benefit of Premier and may be asserted by
Premier regardless of the circumstances giving rise to any such conditions
and, consent may be waived by Premier, in whole or in part, at any time and
from time to time, in their reasonable discretion, in each case, subject to
the terms of the Agreement. The failure by Premier at any
 
                                      27

 
time to exercise any of the foregoing rights shall not be deemed a waiver of
any such right and each such right shall be deemed an ongoing right which may
be asserted at any time and from time to time.
 
  The capitalized terms used in this Annex I shall have the meanings set forth
in the Agreement to which it is annexed.
 
                                       28

 
                                  EXHIBIT "A"
 
                            FORM OF CLASS C WARRANT

 
                                  EXHIBIT "B"
 
                            FORM OF CLASS D WARRANT