Exhibit 1
 
                                  AMENDMENT 5
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                                    TO THE
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                       SUPPLY AND DISTRIBUTION AGREEMENT
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                                    BETWEEN
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                               ICU MEDICAL, INC.
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                                      AND
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                              ABBOTT LABORATORIES
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This Amendment 5, effective this 1st day of January, 1999 ("Effective Date") is
made to the Supply and Distribution Agreement dated April 3, 1995, as amended on
September 9, 1998, November 13, 1998, January 9, 1998 and May 13, 1998 between
ICU Medical, Inc. ("ICU") and Abbott Laboratories ("Abbott") for the purchase
and sales of certain Products (the "Agreement").

The parties agree to amend the Agreement as follows:

1.   Term.  This Agreement shall be effective on the Effective Date set forth
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     herein above and, unless terminated in accordance with Section 15 of the
     Agreement, shall expire on December 31, 2009.

2.   Volume.
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     (a)  The total annual volume of Products shall include Y-CLAVE, bulk
          straight CLAVE and packaged and sterilized CLAVE Male Adapter Plugs.

     (b)  Abbott shall commit to purchase from ICU the total Units of Product
          for the period indicated in Exhibit 1.

     (c)  Abbott shall use its reasonable best commercial efforts to achieve the
          continued growth of the CLAVE family of Products in the total Units of
          Product for the periods indicated in Exhibit 1.

3.   Penalty for Not Ordering Volume Commitments of Product for delivery.
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     (a)  Abbott shall pay a penalty for Product shortfall at the percentage of
          the unit prices applied to the units of Products not ordered for
          delivery against the annual volume commitment as set forth in
          Provision 2 (b) herein above at the percentage rates indicated in
          Exhibit 2.

     (b)  Such penalty shall assume the same mix of CLAVE styles of Product for
          the period of the annual volume commitment in Exhibit 2 as applied to
          1998.

 
4.   Costs.
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     (a)  CLAVE MAP.  The cost of packaged and sterilized CLAVE MAP Product (ICU
          Medical product number L#11956) shall be as specified in Exhibit 3 for
          the Term of the Agreement:

     The parties agree to negotiate in good faith the appropriate pricing for
     units ordered in excess of the cumulative sum of units for which pricing is
     not specified in Exhibit 3.

     (b)  Y-CLAVE and Straight CLAVE.  The costs of the Y-CLAVE and the Straight
          CLAVE Products shall be as specified in Exhibit 3.

5.   Other Terms.
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     (a)  Both parties agree to negotiate in good faith appropriate pricing, and
          volume, as applicable, for other packaged sterile products and a
          special version of the CLAVE integral to a pump set.

     (b)  During the first five (5) years of the Term of this Agreement, as
          defined in paragraph 1 herein, ICU will be the Preferred Supplier of
          needlefree technology to Abbott's Hospital Products Division in the
          United States. As Preferred Supplier, if Abbott's Hospital Products
          Division in the United States elects to seek a third party to develop
          or manufacture needlefree connectors or connector technology, ICU will
          be the supplier of first choice by Abbott for all such connectors and
          connector technology. In all cases, ICU's status as Preferred Supplier
          shall be subject to general market conditions including, but not
          limited to, new technology, timelines, quantities, product features
          and pricing. For as long as ICU continues as Preferred Supplier, ICU
          agrees to timely notify Abbott of improvements to the CLAVE and any
          new needle safe I.V. administration set connector, and give Abbott the
          ability to purchase such products upon initial introduction by ICU
          into the market if the parties agree on contractual terms. After the
          initial five (5) years of the Term of this Agreement, ICU's status as
          Preferred Supplier will be extended automatically for one (1) year
          periods unless such status is terminated by either party by written
          notice at least six months before the renewal date.

     (c)  ICU and Abbott agree to revisit the terms and conditions of the
          Agreement should there be a shift in the market conditions such as
          pricing pressures which would warrant a further reduction in price of
          Product sold to Abbott. If ICU refuses, or is not in a position, to
          offer to Abbott such a further reduction in price of Product sold to
          Abbott, ICU's Preferred Supplier status as set forth in this Amendment
          shall terminate.

     (d)  Both parties agree to restate the Agreement as amended and to
          incorporate standard Abbott supply terms in the Agreement, unless the
          parties agree to other terms, including the maintenance of a term
          similar to Paragraph 9 of the Agreement dealing with tooling
          amortization. The parties agree to begin such discussion by January
          31, 1999.

 
6.   Remaining Terms and Conditions.  All other remaining terms and conditions
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     of the Agreement, as amended, shall remain in full force and effect.

IN WITNESS WHEREOF, the parties, intending to be bound by the terms and
conditions hereof, have caused this Amendment 5 to be signed by their duly
authorized representatives on the dates set forth below.


ABBOTT LABORATORIES                         ICU MEDICAL, INC.

By:  /s/ Richard A. Gonzalez                By:  /s/ Francis J. O'Brien
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     Richard A. Gonzalez                          Francis J. O'Brien
          President                             Chief Financial Officer
        Hospital Products Division

Date:    January 14, 1999                   Date:    January 7, 1999
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ABBOTT LABORATORIES

By:  /s/ Sarah Catterson
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          Sarah Catterson
      Division Vice President
       Corporate Purchasing

Date:    January 14, 1999
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