As filed with the Securities and Exchange Commission on May 8, 1996 Registration No. 333-01927-01 ______________________________________________________________________________ SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 _______________ POST-EFFECTIVE AMENDMENT NO. 1 ON FORM S-8 TO FORM S-4 REGISTRATION STATEMENT Under The Securities Act of 1933* _______________ Cardinal Health, Inc. (Exact name of registrant as specified in its charter) Ohio 31-0958666 (State or other jurisdiction (I.R.S. Employer Identification No.) of incorporation or organization) 5555 Glendon Court, Dublin, Ohio 43016 (Address of Principal Executive Offices) (Zip Code) _______________ AMENDED AND RESTATED 1991 STOCK PLAN OF PYXIS CORPORATION (Full title of the plan) _______________ George H. Bennett, Jr., Executive Vice President, Secretary and General Counsel Cardinal Health, Inc. 5555 Glendon Court Dublin, Ohio 43016 (Name and address of agent for service) (614) 717-5000 (Telephone number, including area code, of agent for service) _______________ CALCULATION OF REGISTRATION FEE ______________________________________________________________________________ Title of Amount Proposed Proposed Amount of securities to to be maximum offering maximum aggregate registration be registered registered(1) price per share(1) offering price fee ______________________________________________________________________________ Common Shares, without par value 1,565,000 (2) (2) (2) ______________________________________________________________________________ (1) Also includes an indeterminable number of additional shares that may become issuable pursuant to the anti-dilution provisions of the Plan. (2) Not applicable. All filing fees payable in connection with the registration of the issuance of these securities were paid in connection with the filing of (a) preliminary proxy materials on Schedule 14A of Pyxis Corporation on March 8, 1996, and (b) the Registrant's Form S-4 Registration Statement (333-01927) on March 25, 1996. * Filed as a Post-Effective Amendment on Form S-8 to such Form S-4 Registration Statement pursuant to the procedure described in Part II under "Introductory Statement." PART II INFORMATION REQUIRED IN THE REGISTRATION STATEMENT INTRODUCTORY STATEMENT Cardinal Health, Inc. (the "Company" or the "Regis- trant") hereby amends its Registration Statement on Form S-4 (No. 333-01927) (the "Form S-4") by filing this Post-Effective Amendment No. 1 on Form S-8 ("Amendment No. 1") with respect to up to 1,565,000 of the Registrant's Common Shares, without par value ("Common Shares"), issuable in connection with the Amended and Restated 1991 Stock Plan (the "Plan") of Pyxis Corporation ("Pyxis"). All such Common Shares were previously included in the Form S-4. On May 7, 1996, Aztec Merger Corp., a Delaware corpo- ration and a wholly owned subsidiary of the Registrant ("AMC"), was merged with and into Pyxis (the "Merger") pursuant to an Agreement and Plan of Merger dated February 7, 1996, among the Registrant, AMC and Pyxis (the "Merger Agreement"). As a result of the Merger, each outstanding share of Pyxis Common Stock (with certain specified exceptions) was converted into Common Shares of the Registrant pursuant to the exchange ratio (the "Exchange Ratio") set forth in the Merger Agreement. Also as a result of the Merger, shares of Pyxis Common Stock are no longer issuable upon the exercise of options to purchase Pyxis Common Stock ("Pyxis Options") pursuant to the Plan. Instead, participants in the Plan will receive in lieu of Pyxis Common Stock that number of Common Shares of the Registrant equal to the number of shares of Pyxis Common Stock issuable immediately prior to the effective time of the Merger upon exercise of a Pyxis Option multiplied by the Exchange Ratio, with an exercise price for such option equal to the exercise price which existed under the corresponding Pyxis Option divided by the Exchange Ratio. The designation of Amendment No. 1 as Registration No. 333-01927-01 denotes that Amendment No. 1 relates only to the Common Shares issuable pursuant to the Plan and that this is the first Post-Effective Amendment to the S-4 filed with respect to such shares. ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE. The documents listed below are incorporated by refer- ence in the registration statement. All documents filed by the Company pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), subsequent to the date of the filing of this registra- tion statement and prior to the filing of a post-effective amendment that indicates that all securities registered hereun- der have been sold, or that de-registers all securities then remaining unsold, shall be deemed to be incorporated by refer- ence in the registration statement and to be a part hereof from the date of the filing of such documents. (a) The Annual Report on Form 10-K of the Company for the fiscal year ended June 30, 1995 filed with the Commission on September 21, 1995; (b) The Company's Current Report on Form 8-K dated August 26, 1995; (c) The Company's Current Report on Form 8-K dated October 23, 1995; (d) The Company's Quarterly Report on Form 10-Q for the quarter ended September 30, 1995 filed with the Commission on November 6, 1995; (e) The Company's Current Report on Form 8-K dated Novem- ber 13, 1995, as amended by the Company's Current Report on Form 8-K/A filed January 18, 1996; (f) The Company's Current Report on Form 8-K dated Janu- ary 10, 1996; (g) The Company's Quarterly Report on Form 10-Q for the quarter ended December 31, 1995 filed with the Commission on February 12, 1996; (h) The Company's Current Report on Form 8-K dated April 22, 1996; (i) The Company's Quarterly Report on Form 10-Q for the quarter ended March 31, 1996 filed with the Commission on May 3, 1996; (j) The Company's Current Report on Form 8-K dated May 7, 1996; and (k) The description of the Company's Common Shares con- tained in the Company's Registration Statement on Form 8-A dated August 19, 1994, pursuant to Section 12 of the Exchange Act. -2- ITEM 5. INTEREST OF NAMED EXPERTS AND COUNSEL. The legality of the Common Shares offered hereby has been passed upon for the Company by Paul S. Williams, Assistant General Counsel of the Company. Mr. Williams holds unvested options to purchase Common Shares of the Company. ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS. Section 1701.13(E) of the Ohio Revised Code sets forth conditions and limitations governing the indemnification of officers, directors, and other persons. Article 6 of the Company's Restated Code of Regula- tions ("Code of Regulations"), as amended, contains certain indemnification provisions adopted pursuant to authority con- tained in Section 1701.13(E) of the Ohio Revised Code. The Company's Code of Regulations provides for the indemnification of its officers, directors, employees, and agents against all expenses with respect to any judgments, fines, and amounts paid in settlement, or with respect to any threatened, pending, or completed action, suit, or proceeding to which they were or are parties or are threatened to be made parties by reason of act- ing in such capacities, provided that it is determined, either by a majority vote of a quorum of disinterested directors of the Company or the shareholders of the Company or otherwise as provided in Section 1701.13(E) of the Ohio Revised Code, that (a) they acted in good faith and in a manner they reasonably believed to be in or not opposed to the best interest of the Company; (b) in any action, suit, or proceeding by or in the right of the Company, they were not, and have not been adjudi- cated to have been, negligent or guilty of misconduct in the performance of their duties to the Company; and (c) with respect to any criminal action or proceeding, that they had no reasonable cause to believe that their conduct was unlawful. Section 1701.13(E) provides that to the extent a director, officer, employee, or agent has been successful on the merits or otherwise in defense of any such action, suit, or proceed- ing, he shall be indemnified against expenses reasonably incurred in connection therewith. At present there are no material claims, actions, suits, or proceedings pending where indemnification would be required under these provisions, and the Company does not know of any such threatened claims, actions, suits, or proceedings which may result in a request for such indemnification. The Company has entered into indemnification con- tracts with each of its directors and executive officers. These contracts generally: (i) confirm the existing indemnity provided to them under the Company's Code of Regulations and -3- assure that this indemnity will continue to be provided; (ii) provide that if the Company does not maintain directors' and officers' liability insurance, the Company will, in effect, become a self-insurer of the coverage; and (iii) provide that, in addition, the directors and officers shall be indemnified to the fullest extent permitted by law against all expenses (including legal fees), judgments, fines, and settlement amounts paid or incurred by them in any action or proceeding, including any action by or in the right of the Company, on account of their service as a director, officer, employee, or agent of the Company or at the request of the Company as a director, officer, employee, or agent of another corporation or enterprise. Coverage under the contracts is excluded: (A) on account of conduct which is finally adjudged to be knowingly fraudulent, deliberately dishonest, or willful misconduct; or (B) if a final court of adjudication shall determine that such indemnification is not lawful; or (C) in respect of any suit in which judgment is rendered for violations of Section 16(b) of the Exchange Act or similar provisions of any federal, state, or local statutory law; or (D) on account of any remuneration paid which is finally adjudged to have been in violation of law; or (E) as to officers who are not directors, with respect to any act or omission which is finally adjudged to have been a violation, other than in good faith, of the Company's Standards of Business Conduct of which the officer then most recently has received written notice. The indemnification agreements are applicable to claims asserted after their effective date, whether arising from acts or omissions occurring before or after their effective date, and associated legal expenses. ITEM 8. EXHIBITS. Exhibit Number Description of Exhibit _____________ ______________________ 5 Opinion of Paul S. Williams as to legality of the Common Shares being registered 23(a) Consent of Deloitte & Touche LLP 23(b) Consent of Arthur Andersen LLP -- Sacramento 23(c) Consent of Arthur Andersen LLP -- St. Louis 23(d) Consent of Ernst & Young LLP 23(e) Consent of Paul S. Williams (included in Opinion filed as Exhibit 5 hereto) 24 Power of attorney (included on the Signature Page of this Form S-8) 99 Amended and Restated 1991 Stock Plan of Pyxis Corporation -4- ITEM 9. UNDERTAKINGS. A. The undersigned Registrant hereby undertakes: (1) To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement: (i) to include any prospectus required by Section 10(a)(3) of the Securities Act of 1933, as amended (the "Securities Act"); (ii) to reflect in the prospectus any facts or events arising after the effective date of the regis- tration statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the regis- tration statement; and (iii) to include any material informa- tion with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration statement; provided, however, that clauses (i) and (ii) do not apply if the informa- tion required to be included in a post-effective amendment by those clauses is contained in periodic reports filed with or furnished to the Securities and Exchange Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the regis- tration statement; (2) That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof; and (3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering. B. The undersigned registrant hereby undertakes that, for purposes of determining any liability under the Secu- rities Act, each filing of the Registrant's annual report pur- suant to Section 13(a) or Section 15(d) of the Exchange Act that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such secu- rities at that time shall be deemed to be the initial bona fide offering thereof. C. Insofar as indemnification for liabilities aris- ing under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the provisions described under Item 6 above or otherwise, the -5- Registrant has been advised that in the opinion of the Securi- ties and Exchange Commission such indemnification is against public policy as expressed in the Securities Act and is, there- fore, unenforceable. In the event that a claim for indemnifi- cation against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by control- ling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against pub- lic policy as expressed in the Securities Act and will be governed by the final adjudication of such issue. -6- SIGNATURES Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly autho- rized, in the City of Dublin, State of Ohio, on the 8th day of May, 1996. CARDINAL HEALTH, INC. By: /s/ Robert D. Walter ______________________________ Robert D. Walter, Chairman and Chief Executive Officer KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Robert D. Walter, George H. Bennett, Jr., and Paul S. Williams, and each of them, severally, as his/her attorney-in-fact and agent, with full power of substitution and resubstitution, for him/her and in his/her name, place, and stead, in any and all capaci- ties, to sign any and all pre- or post-effective amendments to this Registration Statement, and to file the same with all exhibits hereto, and other documents with the Securities and Exchange Commission, granting unto said attorney-in-fact and agent, and each of them, full power and authority to do and perform each and every act and thing requisite or necessary to be done in and about the premises, as fully to all intents and purposes as he/she might or could do in person, hereby ratify- ing and confirming all that said attorneys-in-fact and agents, or any of them, or their or his substitutes, may lawfully do or cause to be done by virtue hereof. Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the fol- lowing persons in the capacities indicated on the 8th day of May, 1996. Signature Title /s/ Robert D. Walter Chairman and Chief Executive ___________________________ Officer (principal executive Robert D. Walter officer) -7- /s/ David Bearman Executive Vice President and ___________________________ Chief Financial Officer and David Bearman Chief Accounting Officer /s/ John F. Finn Director ___________________________ John F. Finn /s/ Robert L. Gerbig Director ___________________________ Robert L. Gerbig /s/ John F. Havens Director ___________________________ John F. Havens /s/ Regina E. Herzlinger Director ___________________________ Regina E. Herzlinger /s/ John C. Kane Director ___________________________ John C. Kane /s/ George R. Manser Director ___________________________ George R. Manser /s/ John B. McCoy Director ___________________________ John B. McCoy /s/ Jerry E. Robertson Director ___________________________ Jerry E. Robertson /s/ L. Jack Van Fossen Director ___________________________ L. Jack Van Fossen /s/ Melburn G. Whitmire Director ___________________________ Melburn G. Whitmire -8- EXHIBIT INDEX _____________ EXHIBIT NUMBER EXHIBIT DESCRIPTION ______________ ___________________ 5 Opinion of Paul S. Williams as to legality of the Common Shares being registered 23(a) Consent of Deloitte & Touche LLP 23(b) Consent of Arthur Andersen LLP -- Sacramento 23(c) Consent of Arthur Andersen LLP -- St. Louis 23(d) Consent of Ernst & Young LLP 23(e) Consent of Paul S. Williams (included in Opinion filed as Exhibit 5 hereto) 24 Power of Attorney (included on the Signature Page of this Form S-8) 99 Amended and Restated 1991 Stock Plan of Pyxis Corporation EXHIBIT 5 May 8, 1996 Cardinal Health, Inc. 5555 Glendon Court Dublin, OH 43016 Gentlemen: I have acted as counsel to Cardinal Health, Inc., an Ohio corporation (the "Company"), in connection with Post- Effective Amendment No. 1 on Form S-8 to the Company's Regis- tration Statement on Form S-4 (the "Registration Statement") filed under the Securities Act of 1933 (the "Act") relating to the issuance of up to 1,565,000 Common Shares, without par value (the "Common Shares"), of the Company pursuant to the Amended and Restated 1991 Stock Plan of Pyxis Corporation (the Plan). In connection with the foregoing, I have examined: (a) the Amended and Restated Articles of Incorporation, as amended, and Restated Code of Regulations, as amended, of the Company, (b) the Plan, and (c) such records of the corporate proceedings of the Company and such other documents as I deemed necessary to render this opinion. Based on such examination, I am of the opinion that the Common Shares available for issuance under the Plan, when issued, delivered and paid for in accordance with the terms and conditions of the Plan, will be legally issued, fully paid and nonassessable. I hereby consent to the filing of this Opinion as Exhibit 5 to the Registration Statement and the reference to me in Item 5 of Part II of the Registration Statement. Very truly yours, /s/ Paul S. Williams Paul S. Williams, Esq. EXHIBIT 23(A) INDEPENDENT AUDITORS' CONSENT We consent to the incorporation by reference in this Registra- tion Statement of Cardinal Health, Inc. on Form S-8 filed as Post Effective Amendment No. 1 to Form S-4 Registration State- ment No. 333-01927 of our report dated August 14, 1995, except for Note 16, as to which the date is August 26, 1995 (which report expresses an unqualified opinion and includes an explanatory paragraph relating to the change in method of accounting for income taxes), appearing in the Annual Report on Form 10-K of Cardinal Health, Inc. for the year ended June 30, 1995, and of our report dated January 5, 1996 (which report expresses an unqualified opinion and includes an explanatory paragraph relating to the change in method of accounting for income taxes), appearing in Form 8-K of Cardinal Health, Inc. dated January 10, 1996. /s/ Deloitte & Touche LLP DELOITTE & TOUCHE LLP Columbus, Ohio May 3, 1996 EXHIBIT 23(B) CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS As independent public accountants, we hereby consent to incor- poration by reference in this Registration Statement of Cardi- nal Health, Inc. on Form S-8 filed as Post Effective Amendment No. 1 to Form S-4 Registration Statement No. 333-01927 of our report on Whitmire Distribution Corporation for the year ended July 3, 1993, dated September 3, 1993, included in Cardinal Health, Inc.'s Form 10K for the year ended June 30, 1995, and in Cardinal Health, Inc.'s Form 8-K dated January 10, 1996, and to all references to our Firm included in this registration statement. /s/ Arthur Andersen LLP Arthur Andersen LLP Sacramento, California May 3, 1996 EXHIBIT 23(C) CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS As independent public accountants, we hereby consent to incor- poration by reference in this Registration Statement of Cardi- nal Health, Inc. on Form S-8 filed as Post Effective Amendment No. 1 to Form S-4 Registration Statement No. 333-01927 of our report on Medicine Shoppe International, Inc. dated November 4, 1994, included in Cardinal Health, Inc.'s Form 8-K dated Novem- ber 16, 1995, and to all references to our Firm included in this registration statement. /s/ Arthur Andersen LLP Arthur Andersen LLP St. Louis, Missouri May 3, 1996 EXHIBIT 23(D) CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS We consent to the incorporation by reference in the Registra- tion Statement (Post Effective Amendment No. 1 on Form S-8 to Form S-4 No. 333-01927-01) of Cardinal Health, Inc. pertaining to the Amended and Restated 1991 Stock Plan of Pyxis Corpora- tion of our report dated January 30, 1996, except for Note 6, Note 7 ("Stockholder Rights Plan"), and Note 13, for which the date is February 7, 1996, with respect to the consolidated financial statements of Pyxis Corporation included in the Cur- rent Report on Form 8-K of Cardinal Health, Inc., filed with the Securities and Exchange Commission. /s/ Ernst & Young LLP ERNST & YOUNG LLP San Diego, California May 3, 1996 EXHIBIT 99 AMENDED AND RESTATED 1991 STOCK PLAN OF PYXIS CORPORATION SECTION 1. Establishment and Purpose. The Plan was established on March 25, 1991, to offer directors and selected employees, advisors and consultants an opportunity to acquire a proprietary interest in the success of the Company, or to increase such interest, by purchasing Shares of the Company's Common Stock. The Plan was most recently amended and restated by the Board of Directors on January 30, 1995, to, among other things, increase the number of shares available for grants, which amendment and restatement was ap- proved by the Company's stockholders on May 25, 1995. The Plan provides both for the direct award or sale of Shares and for the grant of Options to purchase Shares. Options granted under the Plan may include Nonstatutory Options as well as ISO's in- tended to qualify under section 422 of the Code. The Plan is intended to comply in all respects with Rule 16b-3 (or its successor) under the Exchange Act and shall be construed accordingly. SECTION 2. Definitions. (a) "Board of Directors" shall mean the Board of Directors of the Company, as constituted from time to time. (b) "Change in Control" shall mean the occurrence of either of the following events: (i) A change in the composition of the Board of Directors, as a result of which fewer than one-half of the incumbent directors are directors who either: (A) Had been directors of the Company 24 months prior to such change; or (B) Were elected, or nominated for election, to the Board of Directors with the affirmative votes of at least a majority of the directors who had been directors of the Company 24 months prior to such change and who were still in office at the time of the election or nomination; or (ii) Any "person" (as such term is used in sec- tions 13(d) and 14(d) of the Exchange Act) by the acquisition or aggregation of securities is or be- comes the beneficial owner, directly or indirectly, of securities of the Company representing 50 percent or more of the combined voting power of the Company's then outstanding securities ordinarily (and apart from rights accruing under special circumstances) having the right to vote at elections of directors (the "Base Capital Stock"); except that any change in the relative beneficial ownership of the Company's securities by any person resulting solely from a re- duction in the aggregate number of outstanding shares of Base Capital Stock, and any decrease thereafter in such person's ownership of securities, shall be dis- regarded until such person increases in any manner, directly or indirectly, such person's beneficial own- ership of any securities of the Company. (c) "Code" shall mean the Internal Revenue Code of 1986, as amended. (d) "Committee" shall mean a committee of the Board of Directors, as described in Section 3(a). (e) "Company" shall mean Pyxis Corporation, a Delaware corporation. (f) "Employee" shall mean (i) any individual who is a common-law employee of the Company or of a Subsidiary, (ii) an Outside Director and (iii) an independent contractor who performs services for the Company or a Subsidiary and who is not a member of the Board of Directors. Service as an Outside Director or independent contractor shall be considered employ- ment for all purposes of the Plan, except as provided in Sub- sections (a) and (b) of Section 4. -2- (g) "Exchange Act" shall mean the Securities Exchange Act of 1934, as amended. (h) "Exercise Price" shall mean the amount for which one Share may be purchased upon exercise of an Option, as spec- ified by the Committee in the applicable Stock Option Agree- ment. (i) "Fair Market Value" shall mean the market price of Stock, determined by the Committee as follows: (i) If Stock was traded over-the-counter on the date in question but was not traded on the Nasdaq Stock Market or the Nasdaq National Market, then the Fair Market Value shall be equal to the mean between the last reported representative bid and asked prices quoted for such date by the principal automated inter-dealer quotation system on which stock is quoted or, if the stock is not quoted on any such system, by the "Pink Sheets" published by the National Quotation Bureau, Inc.; (ii) If Stock was traded over-the-counter on the date in question and was traded on the Nasdaq Stock Market or the Nasdaq National Market, then the Fair Market Value shall be equal to the last-transaction price quoted for such date by the Nasdaq Stock Market or the Nasdaq National Market; (iii) If Stock was traded on a stock exchange on the date in question, then the Fair Market Value shall be equal to the closing price reported by the applicable composite-transactions report for such date; and (iv) If none of the foregoing provisions is ap- plicable, then the Fair Market Value shall be deter- mined by the Committee in good faith on such basis as it deems appropriate. In all cases, the determination of Fair Market Value by the Committee shall be conclusive and binding on all persons. -3- (j) "ISO" shall mean an employee incentive stock option described in section 422(b) of the Code. (k) "Nonstatutory Option" shall mean a stock option not described in sections 422(b) or 423(b) of the Code. (l) "Offeree" shall mean an individual to whom the Committee has offered the right to acquire Shares under the Plan (other than upon exercise of an Option). (m) "Option" shall mean an ISO or Nonstatutory Option granted under the Plan and entitling the holder to pur- chase Shares. (n) "Optionee" shall mean an individual who holds an Option. (o) "Outside Director" shall mean a member of the Board of Directors who is not a common-law employee of the Company or of a Subsidiary. (p) "Plan" shall mean this 1991 Stock Plan of Pyxis Corporation. (q) "Purchase Price" shall mean the consideration for which one Share may be acquired under the Plan (other than upon exercise of an Option), as specified by the Committee. (r) "Service" shall mean service as an Employee. (s) "Share" shall mean one share of Stock, as ad- justed in accordance with Section 9 (if applicable). (t) "Stock" shall mean the Common Stock of the Company. (u) "Stock Option Agreement" shall mean the agree- ment between the Company and an Optionee which contains the terms, conditions and restrictions pertaining to his or her Option. -4- (v) "Stock Purchase Agreement" shall mean the agree- ment between the Company and an Offeree who acquires Shares under the Plan which contains the terms, conditions and re- strictions pertaining to the acquisition of such Shares. (w) "Subsidiary" shall mean any corporation, if the Company and/or one or more other Subsidiaries own not less than 50 percent of the total combined voting power of all classes of outstanding stock of such corporation. A corporation that at- tains the status of a Subsidiary on a date after the adoption of the Plan shall be considered a Subsidiary commencing as of such date. (x) "Total and Permanent Disability" shall mean that the Optionee is unable to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted, or can be expected to last, for a continuous period of not less than one year. SECTION 3. Administration. (a) Committee Membership. The Plan shall be admin- istered by the Committee. The Committee shall consist of two or more disinterested directors of the Company and shall meet such other requirements as may be established from time to time by the Securities and Exchange Commission for plans intended to qualify for exemption under Rule 16b-3 (or its successor) under the Exchange Act. The Board of Directors may appoint a separ- ate committee of the Board of Directors, composed of one or more directors of the Company who need not be disinterested directors, who may administer the Plan with respect to Employees who are not officers or directors of the Company, may grant Shares and Options under the Plan to such Employees and may determine the timing, number of Shares and other terms of such grants. (b) Disinterested Directors. A member of the Board of Directors shall be deemed "disinterested" only if he or she satisfies (i) such requirements as the Securities and Exchange Commission may establish for disinterested administrators of plans designed to qualify for exemption under Rule 16b-3 (or its successor) under the Exchange Act and (ii) such require- ments as the Internal Revenue Service may establish for outside directors acting under plans intended to qualify for exemption -5- under section 162(m)(4)(C) of the Code. An Outside Director shall not fail to be "disinterested" solely because he or she receives the Nonstatutory Options described in Section 4(b). (c) Committee Procedures. The Committee shall designate one of its members as chairman. The Committee may hold meetings at such times and places as it shall determine. The acts of a majority of the Committee members present at meetings at which a quorum exists, or acts reduced to or approved in writing by all Committee members, shall be valid acts of the Committee. (d) Committee Responsibilities. Subject to the pro- visions of the Plan, the Committee shall have full authority and discretion to take the following actions: (i) To interpret the Plan and to apply its pro- visions; (ii) To adopt, amend or rescind rules, proce- dures and forms relating to the Plan; (iii) To authorize any person to execute, on be- half of the Company, any instrument required to carry out the purposes of the Plan; (iv) To determine when Shares are to be awarded or offered for sale and when Options are to be granted under the Plan; (v) To select the Offerees and Optionees; (vi) To determine the number of Shares to be offered to each Offeree or to be made subject to each Option; (vii) To prescribe the terms and conditions of each award or sale of Shares, including (without lim- itation) the Purchase Price, and to specify the pro- visions of the Stock Purchase Agreement relating to such award or sale; -6- (viii) To prescribe the terms and conditions of each Option, including (without limitation) the Exer- cise Price, to determine whether such Option is to be classified as an ISO or as a Nonstatutory Option, and to specify the provisions of the Stock Option Agree- ment relating to such Option; (ix) To amend any outstanding Stock Purchase Agreement or Stock Option Agreement, subject to applicable legal restrictions and to the consent of the Offeree or Optionee who entered into such agreement; (x) To prescribe the consideration for the grant of each Option or other right under the Plan and to determine the sufficiency of such consider- ation; and (xi) To take any other actions deemed necessary or advisable for the administration of the Plan. All decisions, interpretations and other actions of the Commit- tee shall be final and binding on all Offerees, all Optionees, and all persons deriving their rights from an Offeree or Optionee. No member of the Committee shall be liable for any action that he or she has taken or has failed to take in good faith with respect to the Plan, any Option, or any right to acquire Shares under the Plan. SECTION 4. Eligibility. (a) General Rules. Only Employees (including, with- out limitation, independent contractors who are not members of the Board of Directors) shall be eligible for designation as Optionees or Offerees by the Committee. In addition, only Em- ployees who are common-law employees of the Company or a Sub- sidiary shall be eligible for the grant of ISO's. Employees who are Outside Directors shall only be eligible for the grant of the Nonstatutory Options described in Subsection (b) below. (b) Outside Directors. Any other provision of the Plan notwithstanding, the participation of Outside Directors in the Plan shall be subject to the following restrictions: -7- (i) Outside Directors shall receive no grants other than the Nonstatutory Options described in this Subsection (b). (ii) Each Outside Director who first becomes a member of the Board of Directors after the effective date of the Company's registration statement on Form 8-A under the Exchange Act shall receive a one-time grant of a Nonstatutory Option covering 10,000 Shares (subject to adjustment under Article 9). Such Non- statutory Option shall be granted on the date when such Outside Director first joins the Board of Direc- tors and shall become exercisable ratably over a two- year period. (iii) Upon the conclusion of each regular annual meeting of the Company's stockholders, each Outside Director who will continue serving as a member of the Board of Directors thereafter shall receive a Non- statutory Option covering 2,000 Shares (subject to adjustment under Article 9), except that such Non- statutory Option shall not be granted in the calendar year in which the same Outside Director received the Nonstatutory Option described in Paragraph (ii) above. Nonstatutory Options granted under this Para- graph (iii) shall become exercisable ratably over a two-year period. (iv) All Nonstatutory Options granted to an Outside Director under this Subsection (b) shall also become exercisable in full in the event of (A) the termination of such Outside Director's service be- cause of death, Total and Permanent Disability or voluntary retirement at or after age 65 or (B) a Change in Control with respect to the Company. (v) The Exercise Price under all Nonstatutory Options granted to an Outside Director under this Subsection (b) shall be equal to 100 percent of the Fair Market Value of a Share on the date of grant, payable in one of the forms described in Subsection (a), (b), (c) or (d) of Section 8. -8- (vi) All Nonstatutory Options granted to an Out- side Director under this Subsection (b) shall termi- nate on the earliest of (A) the 10th anniversary of the date of grant, (B) the date three months after the termination of such Outside Director's service for any reason other than death or Total and Perma- nent Disability or (C) the date 12 months after the termination of such Outside Director's service be- cause of death or Total and Permanent Disability. The Committee may provide that the Nonstatutory Options that otherwise would be granted to an Outside Director under this Subsection (b) shall instead be granted to an affiliate of such Outside Director. Such affiliate shall then be deemed to be an Outside Director for purposes of the Plan, provided that the service-related vesting and termination provisions pertaining to the Nonstatutory Options shall be applied with regard to the service of the Outside Director. (c) Ten-Percent Stockholders. An Employee who owns more than 10 percent of the total combined voting power of all classes of outstanding stock of the Company or any of its Sub- sidiaries shall not be eligible for the grant of an ISO unless (i) the Exercise Price is at least 110 percent of the Fair Market Value of a Share on the date of grant and (ii) such ISO by its terms is not exercisable after the expiration of five years from the date of grant. (d) Attribution Rules. For purposes of Subsection (c) above, in determining stock ownership, an Employee shall be deemed to own the stock owned, directly or indirectly, by or for such Employee's brothers, sisters, spouse, ancestors and lineal descendants. Stock owned, directly or indirectly, by or for a corporation, partnership, estate or trust shall be deemed to be owned proportionately by or for its stockholders, part- ners or beneficiaries. Stock with respect to which such Em- ployee holds an option shall not be counted. (e) Outstanding Stock. For purposes of Subsection (c) above, "outstanding stock" shall include all stock actually issued and outstanding immediately after the grant. "Outstand- ing stock" shall not include shares authorized for issuance under outstanding options held by the Employee or by any other person. -9- SECTION 5. Stock Subject to Plan. (a) Basic Limitation. Shares offered under the Plan shall be authorized but unissued Shares or treasury Shares. The aggregate number of Shares which may be issued under the Plan (upon exercise of Options or other rights to acquire Shares) shall not exceed 7,100,000 Shares, subject to adjust- ment pursuant to Section 9. The number of Shares which are subject to Options or other rights outstanding at any time un- der the Plan shall not exceed the number of Shares which then remain available for issuance under the Plan. The Company, during the term of the Plan, shall at all times reserve and keep available sufficient Shares to satisfy the requirements of the Plan. (b) Additional Shares. In the event that any outstanding Option or other right for any reason expires or is canceled or otherwise terminated, the Shares allocable to the unexercised portion of such Option or other right shall again be available for the purposes of the Plan. In the event that Shares issued under the Plan are reacquired by the Company pur- suant to a forfeiture provision, a right of repurchase or a right of first refusal, such Shares shall again be available for the purposes of the Plan. SECTION 6. Terms and Conditions of Awards or Sales. (a) Stock Purchase Agreement. Each award or sale of Shares under the Plan (other than upon exercise of an Option) shall be evidenced by a Stock Purchase Agreement between the Offeree and the Company. Such award or sale shall be subject to all applicable terms and conditions of the Plan and may be subject to any other terms and conditions which are not incon- sistent with the Plan and which the Committee deems appropriate for inclusion in a Stock Purchase Agreement. The provisions of the various Stock Purchase Agreements entered into under the Plan need not be identical. (b) Duration of Offers and Nontransferability of Rights. Any right to acquire Shares under the Plan (other than an Option) shall automatically expire if not exercised by the Offeree within 30 days after the grant of such right was com- municated to the Offeree by the Committee. Such right shall not be transferable and shall be exercisable only by the Of- feree to whom such right was granted. -10- (c) Purchase Price. The Purchase Price of Shares to be offered under the Plan shall not be less than the par value of such Shares. Subject to the preceding sentence, the Pur- chase Price shall be determined by the Committee at its sole discretion. The Purchase Price shall be payable in a form des- cribed in Section 8. (d) Withholding Taxes. As a condition to the award, sale or vesting of Shares, the Offeree shall make such arrange- ments as the Committee may require for the satisfaction of any federal, state, local or foreign withholding tax obligations that arise in connection with such Shares. The Committee may permit the Offeree to satisfy all or part of his or her tax obligations related to such Shares by having the Company with- hold a portion of any Shares that otherwise would be issued to him or her or by surrendering any Shares that previously were acquired by him or her. The Shares withheld or surrendered shall be valued at their Fair Market Value on the date when taxes otherwise would be withheld in cash. The payment of taxes by assigning Shares to the Company, if permitted by the Committee, shall be subject to such restrictions as the Commi- ttee may impose, including any restrictions required by rules of the Securities and Exchange Commission. (e) Restrictions on Transfer of Shares. Any Shares awarded or sold under the Plan shall be subject to such special forfeiture conditions, rights of repurchase, rights of first refusal and other transfer restrictions as the Committee may determine. Such restrictions shall be set forth in the appli- cable Stock Purchase Agreement and shall apply in addition to any general restrictions that may apply to all holders of Shares. SECTION 7. Terms and Conditions of Options. (a) Stock Option Agreement. Each grant of an Option under the Plan shall be evidenced by a Stock Option Agreement between the Optionee and the Company. Such Option shall be subject to all applicable terms and conditions of the Plan and may be subject to any other terms and conditions which are not inconsistent with the Plan and which the Committee deems appro- priate for inclusion in a Stock Option Agreement. The pro- visions of the various Stock Option Agreements entered into under the Plan need not be identical. -11- (b) Number of Shares. Each Stock Option Agreement shall specify the number of Shares that are subject to the Option and shall provide for the adjustment of such number in accordance with Section 9. Options granted to any Optionee in a single calendar year shall in no event cover more than 300,000 Shares, subject to adjustment in accordance with Section 9. The Stock Option Agreement shall also specify whether the Option is an ISO or a Nonstatutory Option. (c) Exercise Price. Each Stock Option Agreement shall specify the Exercise Price. The Exercise Price of an ISO shall not be less than 100 percent of the Fair Market Value of a Share on the date of grant, except as otherwise provided in Section 4(c). The Exercise Price of a Nonstatutory Option shall not be less than the par value of a Share. Subject to the preceding two sentences, the Exercise Price under any Option shall be determined by the Committee at its sole discre- tion. The Exercise Price shall be payable in a form described in Section 8. (d) Withholding Taxes. As a condition to the exer- cise of an Option, the Optionee shall make such arrangements as the Committee may require for the satisfaction of any federal, state, local or foreign withholding tax obligations that arise in connection with such exercise. The Optionee shall also make such arrangements as the Committee may require for the satis- faction of any federal, state, local or foreign withholding tax obligations that may arise in connection with the disposition of Shares acquired by exercising an Option. The Committee may permit the Optionee to satisfy all or part of his or her tax obligations related to the Option by having the Company with- hold a portion of any Shares that otherwise would be issued to him or her or by surrendering any Shares that previously were acquired by him or her. Such Shares shall be valued at their Fair Market Value on the date when taxes otherwise would be withheld in cash. The payment of taxes by assigning Shares to the Company, if permitted by the Committee, shall be subject to such restrictions as the Committee may impose, including any restrictions required by rules of the Securities and Exchange Commission. (e) Exercisability. Each Stock Option Agreement shall specify the date when all or any installment of the Option is to become exercisable. The vesting of any Option shall be determined by the Committee at its sole discretion, except that each Option shall become exercisable in full in the event of the Optionee's death. A Stock Option Agreement may -12- also provide for accelerated exercisability in the event of the Optionee's Total and Permanent Disability or retirement, or other events. (f) Effect of Change in Control. The Committee may determine, at the time of granting an Option or thereafter, that such Option shall become exercisable on an accelerated basis in the event that a Change in Control occurs with respect to the Company. If the Committee finds that there is a reason- able possibility that, within the succeeding six months, a Change in Control will occur with respect to the Company, then the Committee may determine that all outstanding Options shall be exercisable on an accelerated basis. (g) Term. Each Stock Option Agreement shall specify the term of the Option. The term shall not exceed 10 years from the date of grant, except as otherwise provided in Section 4(c). Subject to the preceding sentence, the Committee at its sole discretion shall determine when an Option is to expire. (h) Nontransferability. During an Optionee's life- time, such Optionee's Options shall be exercisable only by him or her and shall not be transferable. In the event of an Optionee's death, such Optionee's Option(s) shall not be trans- ferable other than by will, by a beneficiary designation execu- ted by the Optionee and delivered to the Company or by the laws of descent and distribution. (i) No Rights as a Stockholder. An Optionee, or a transferee of an Optionee, shall have no rights as a stock- holder with respect to any Shares covered by his or her Option until the date of the issuance of a stock certificate for such Shares. No adjustments shall be made, except as provided in Section 9. (j) Modification, Extension and Renewal of Options. Within the limitations of the Plan, the Committee may modify, extend or renew outstanding Options or may accept the cancella- tion of outstanding Options (to the extent not previously exer- cised) in return for the grant of new Options at the same or a different price. The foregoing notwithstanding, no modifica- tion of an Option shall, without the consent of the Optionee, impair such Optionee's rights or increase his or her obliga- tions under such Option. -13- (k) Restrictions on Transfer of Shares. Any Shares issued upon exercise of an Option may be subject to such special forfeiture conditions, rights of repurchase, rights of first refusal and other transfer restrictions as the Committee may determine. Such restrictions shall be set forth in the applicable Stock Option Agreement and shall apply in addition to any general restrictions that may apply to all holders of Shares. SECTION 8. Payment for Shares. (a) General Rule. The entire Purchase Price or Exercise Price of Shares issued under the Plan shall be payable in lawful money of the United States of America at the time when such Shares are purchased, except as follows: (i) In the case of Shares sold under the terms of a Stock Purchase Agreement subject to the Plan, payment shall be made only pursuant to the express provisions of such Stock Purchase Agreement. How- ever, the Committee (at its sole discretion) may specify in the Stock Purchase Agreement that payment may be made in one or both of the forms described in Subsections (e) and (f) below. (ii) In the case of an ISO granted under the Plan, payment shall be made only pursuant to the ex- press provisions of the applicable Stock Option Agreement. However, the Committee (at its sole dis- cretion) may specify in the Stock Option Agreement that payment may be made pursuant to Subsections (b), (c), (d) or (f) below. (iii) In the case of a Nonstatutory Option granted under the Plan, the Committee (at its sole discretion) may accept payment pursuant to Subsections (b), (c), (d) or (f) below. (b) Surrender of Stock. To the extent that this Subsection (b) is applicable, payment may be made all or in part with Shares which have already been owned by the Optionee or his or her representative for more than 12 months and which are surrendered to the Company in good form for transfer. Such -14- Shares shall be valued at their Fair Market Value on the date when the new Shares are purchased under the Plan. (c) Exercise/Sale. To the extent that this Subsec- tion (c) is applicable, payment may be made by the delivery (on a form prescribed by the Company) of an irrevocable direction to a securities broker approved by the Company to sell Shares and to deliver all or part of the sales proceeds to the Company in payment of all or part of the Exercise Price and any with- holding taxes. (d) Exercise/Pledge. To the extent that this Sub- section (d) is applicable, payment may be made by the delivery (on a form prescribed by the Company) of an irrevocable direc- tion to pledge Shares to a securities broker or lender approved by the Company, as security for a loan, and to deliver all or part of the loan proceeds to the Company in payment of all or part of the Exercise Price and any withholding taxes. (e) Services Rendered. To the extent that this Sub- section (e) is applicable, Shares may be awarded under the Plan in consideration of services rendered to the Company or a Sub- sidiary prior to the award. If Shares are awarded without the payment of a Purchase Price in cash, the Committee shall make a determination (at the time of the award) of the value of the services rendered by the Offeree and the sufficiency of the consideration to meet the requirements of Section 6(c). (f) Promissory Note. To the extent that this Sub- section (f) is applicable, a portion of the Purchase Price or Exercise Price, as the case may be, of Shares issued under the Plan may be payable by a full-recourse promissory note, pro- vided that (i) the par value of such Shares must be paid in lawful money of the United States of America at the time when such Shares are purchased, (ii) the Shares are security for payment of the principal amount of the promissory note and in- terest thereon and (iii) the interest rate payable under the terms of the promissory note shall be no less than the minimum rate (if any) required to avoid the imputation of additional interest under the Code. Subject to the foregoing, the Commit- tee (at its sole discretion) shall specify the term, interest rate, amortization requirements (if any) and other provisions of such note. -15- SECTION 9. Adjustment of Shares. (a) General. In the event of a subdivision of the outstanding Stock, a declaration of a dividend payable in Shares, a declaration of a dividend payable in a form other than Shares in an amount that has a material effect on the value of Shares, a combination or consolidation of the out- standing Stock (by reclassification or otherwise) into a lesser number of Shares, a recapitalization, a spinoff or a similar occurrence, the Committee shall make appropriate adjustments in one or more of (i) the number of Shares available for future grants under Section 5, (ii) the number of Nonstatutory Options to be granted to Outside Directors under Section 4(b), (iii) the limit set forth in Section 7(b), (iv) the number of Shares covered by each outstanding Option or (v) the Exercise Price under each outstanding Option. (b) Reorganizations. In the event that the Company is a party to a merger or other reorganization, outstanding Options shall be subject to the agreement of merger or reorga- nization. Such agreement shall provide for the assumption of outstanding Options by the surviving corporation or its parent, for their continuation by the Company (if the Company is a sur- viving corporation), for payment of a cash settlement equal to the difference between the amount to be paid for one Share un- der such agreement and the Exercise Price, or for the accel- eration of their exercisability followed by the cancellation of Options not exercised, in all cases without the Optionees' con- sent. Any cancellation shall not occur until after such accel- eration is effective and Optionees have been notified of such acceleration. In the case of Options that have been outstan- ding for less than 12 months, a cancellation need not be pre- ceded by an acceleration. (c) Reservation of Rights. Except as provided in this Section 9, an Optionee or Offeree shall have no rights by reason of any subdivision or consolidation of shares of stock of any class, the payment of any dividend or any other increase or decrease in the number of shares of stock of any class. Any issue by the Company of shares of stock of any class, or secu- rities convertible into shares of stock of any class, shall not affect, and no adjustment by reason thereof shall be made with respect to, the number or Exercise Price of Shares subject to an Option. The grant of an Option pursuant to the Plan shall not affect in any way the right or power of the Company to make adjustments, reclassifications, reorganizations or changes of its capital or business structure, to merge or consolidate or -16- to dissolve, liquidate, sell or transfer all or any part of its business or assets. SECTION 10. Securities Laws. Shares shall not be issued under the Plan unless the issuance and delivery of such Shares complies with (or is ex- empt from) all applicable requirements of law, including (with- out limitation) the Securities Act of 1933, as amended, the rules and regulations promulgated thereunder, state securities laws and regulations, and the regulations of any stock exchange on which the Company's securities may then be listed. SECTION 11. No Retention Rights. Neither the Plan nor any Option shall be deemed to give any individual a right to remain an employee, consultant or director of the Company or a Subsidiary. The Company and its Subsidiaries reserve the right to terminate the service of any employee, consultant or director at any time, with or with- out cause, subject to applicable laws, the Company's certifi- cate of incorporation and bylaws and a written employment agreement (if any). SECTION 12. Duration and Amendments. (a) Term of the Plan. The Plan, as set forth here- in, shall become effective on January 30, 1995, the date the Board of Directors amended and restated the Plan, subject to the approval of the Company's stockholders. In the event the stockholders fail to approve the amendment to the Plan at the 1995 annual meeting of stockholders, any Option grants or Stock awards made in excess of an aggregate of 6,100,000 Shares shall be null and void. The Plan shall terminate automatically on January 29, 2005, and may be terminated on any earlier date pursuant to Subsection (b) below. (b) Right to Amend or Terminate the Plan. The Board of Directors may amend, suspend or terminate the Plan at any time and for any reason, except that the provisions of Section 4(b) relating to the amount, price and timing of grants to Outside Directors shall not be amended more than once in any -17- six-month period. An amendment of the Plan shall be subject to the approval of the Company's stockholders if it: (i) Increases the number of Shares available for issuance under the Plan (except as provided in Section 9); (ii) Changes the class of persons who are eli- gible for the grant of ISO's; or (iii) To the extent required by Rule 16b-3 (or any successor) under the Exchange Act, materially increases the benefits accruing to participants under the Plan or materially modifies the requirements as to eligibility for participation in the Plan. Stockholder approval shall not be required for any other amend- ment of the Plan. (c) Effect of Amendment or Termination. No Shares shall be issued or sold under the Plan after the termination thereof, except upon exercise of an Option granted prior to such termination. The termination of the Plan, or any amend- ment thereof, shall not affect any Share previously issued or any Option previously granted under the Plan. SECTION 13. Execution. To record the amendment and restatement of the Plan by the Board of Directors on January 30, 1995, the Company has caused its authorized officer to execute the same. PYXIS CORPORATION By:/s/ Ronald R. Taylor ____________________________ Chief Executive Officer -18-