UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                    FORM 8-K
                                 Current Report


                       Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934



                Date of Report (date of earliest event reported):

                                October 31, 2005



                     MEDICAL STAFFING NETWORK HOLDINGS, INC.
             (Exact name of registrant as specified in its charter)



    Delaware                             1-31299              65-0865171
- ----------------                 -----------------------    -------------
(State or other jurisdiction     (Commission File Number)    (IRS Employer
 of incorporation)                                           Identification
                                                               Number)

                901 Yamato Road, Suite 110, Boca Raton, FL 33431
                ------------------------------------------------
                    (Address of principal executive offices)

             Registrant's telephone number, including area code:  561-322-1300
                                                                  ------------

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

     [ ] Written communications pursuant to Rule 425 under the Securities Act
(17 CFR 230.425)

     [ ] Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17
CFR 240.14a-12)

     [ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the
Exchange Act (17 CFR 240.14d-2(b))

     [ ] Pre-commencement communications pursuant to Rule 13e-4(c) under the
Exchange Act (17 CFR 240.13e-4(c))




Item 7.01  Regulation FD Disclosure.

     The registrant is attaching a copy of a press release dated October 31,
2005, as Exhibit 99.1.

Item 9.01  Financial Statements and Exhibits.

           (a) Not Applicable.

           (b) Not Applicable.

           (c) Exhibits:

                   99.1 Press Release dated October 31, 2005.

Limitation on Incorporation by Reference

In accordance with General Instruction B.2 of Form 8-K, the information in this
report (including the exhibit) is furnished pursuant to Item 7.01 and shall not
be deemed to be "filed" for the purposes of Section 18 of the Securities
Exchange Act of 1934, as amended, or otherwise subject to liabilities of that
Section, unless we specifically incorporate it by reference in a document filed
under the Securities Act of 1933 or the Securities Exchange Act of 1934. The
filing of this Current Report on Form 8-K is not an admission as to the
materiality of any information in this report that is required to be disclosed
solely by Regulation FD.

                                       - 2 -



                                    SIGNATURE
                                    ---------

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.



Date:  October 31, 2005                 MEDICAL STAFFING NETWORK HOLDINGS, INC.



                                        By:  /s/ N. Larry McPherson
                                             ----------------------
                                             N. Larry McPherson
                                             Chief Financial Officer





                                  EXHIBIT INDEX

Exhibit No.       Description

99.1              Press Release dated October 31, 2005.