UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934. Commission File Number 0-27406 CONNETICS CORPORATION (Exact name of registrant as specified in its charter) - -------------------------------------------------------------------------------- Connetics Corporation 3160 Porter Drive Palo Alto, CA 94304 (650) 843-2800 (Address, including zip code, and telephone number, including area code, of registrant's principal executive offices) - -------------------------------------------------------------------------------- All securities listed on Exhibit A hereto. (Title of each class of securities covered by this Form) - -------------------------------------------------------------------------------- None. (Title of all other classes of securities for which a duty to file reports under Section 13(a) or 15(d) remains) - -------------------------------------------------------------------------------- Please place an X in the box(es) to designate the appropriate rule provision(s) relied upon to terminate or suspend the duty to file reports: Rule 12g-4(a)(1)(i) [X] Rule 12h-3(b)(1)(ii) [ ] Rule 12g-4(a)(1)(ii) [ ] Rule 12h-3(b)(2)(i) [ ] Rule 12g-4(a)(2)(i) [ ] Rule 12h-3(b)(2)(ii) [ ] Rule 12g-4(a)(2)(ii) [ ] Rule 15d-6 [ ] Rule 12h-3(b)(1)(i) [X] Approximate number of holders of record as of the certification or notice date: See Exhibit A hereto. Pursuant to the requirements of the Securities Exchange Act of 1934, Connetics Corporation has caused this certification and notice to be signed on its behalf by the undersigned duly authorized person. Date: February 12, 2007 By: /s/ Michael Cornelius ----------------------- -------------------------------------------- Name: Michael Cornelius Title: Executive Vice President & Treasurer Exhibit A - -------------------------------------------------- ----------------------------- Security Record Holders - -------------------------------------------------- ----------------------------- Common Stock, par value $0.001 1 - -------------------------------------------------- ----------------------------- Preferred Stock Purchase Rights 0 - -------------------------------------------------- ----------------------------- 2.00% Convertible Senior Notes due March 30, 2015 0 - -------------------------------------------------- ----------------------------- 2.25% Convertible Senior Notes due May 30, 2008 0 - -------------------------------------------------- -----------------------------