UNITED STATES

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549



FORM N-PX



ANNUAL REPORT OF PROXY VOTING RECORD OF REGISTERED MANAGEMENT INVESTMENT COMPANY



Investment Company Act file number 811-09637



Name of Fund: BlackRock Large Cap Series Funds, Inc. BlackRock Large Cap Core

Fund

BlackRock Large Cap Core Retirement Portfolio BlackRock Large Cap Growth Fund

BlackRock Large Cap Growth Retirement Portfolio BlackRock Large Cap Value Fund

BlackRock Large Cap Value Retirement Portfolio



Fund Address: 100 Bellevue Parkway, Wilmington, DE 19809



Name and address of agent for service: Donald C. Burke, Chief Executive

Officer, BlackRock Large Cap Series Funds, Inc., 800 Scudders Mill Road,

Plainsboro, NJ, 08536. Mailing address: P.O. Box 9011, Princeton, NJ, 08543-9011



Registrant's telephone number, including area code: (800) 441-7762 Date of

fiscal year end: 10/31 Date of reporting period: 07/01/2007 -- 06/30/2008



Item 1 -- Proxy Voting Record -- There were no matters relating to a portfolio

security considered at any shareholder meeting held during the period ended

June 30, 2008 with respect to which the registrant was entitled to vote.



Pursuant to the requirements of the Investment Company Act of 1940, the

registrant has duly caused this report to be signed on its behalf by the

undersigned, thereunto duly authorized.



BlackRock Large Cap Series Funds, Inc.



By: /s/ Donald C. Burke

Donald C. Burke Chief Executive Officer of

BlackRock Large Cap Series Funds, Inc.



Date: August 15, 2008