Exhibit 99.1

                CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350,

                             AS ADOPTED PURSUANT TO

                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002



     In  connection  with  the  Quarterly  Report  on Form  10-Q  of  CollaGenex
Pharmaceuticals, Inc. (the "Company") for the period ended September 30, 2002 as
filed with the  Securities  and  Exchange  Commission  on the date  hereof  (the
"Report"), the undersigned,  Brian M. Gallagher,  Ph.D., Chief Executive Officer
of the Company, and Nancy C. Broadbent,  Chief Financial Officer of the Company,
each hereby certifies, pursuant to 18 U.S.C. Section 1350, that:

     (1) The Report fully  complies  with the  requirements  of Section 13(a) or
15(d) of the Securities Exchange Act of 1934; and

     (2)  The  information  contained  in the  Report  fairly  presents,  in all
material  respects,  the  financial  condition  and results of operations of the
Company.



                                    /s/ Brian M. Gallagher  , Ph.D.
                                    -------------------------------
Dated: November 14, 2002            Brian M. Gallagher, Ph.D.
                                    Chief Executive Officer



                                    /s/ Nancy C. Broadbent
                                    -------------------------------
Dated: November 14, 2002            Nancy C. Broadbent
                                    Chief Financial Officer