SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                         -------------------------------

                                    FORM 8-K

                                 CURRENT REPORT

                     PURSUANT TO SECTION 13 OR 15(d) OF THE

                         SECURITIES EXCHANGE ACT OF 1934


         Date of report (Date of earliest event reported) July 16, 2003
                                                          -------------


                        CollaGenex Pharmaceuticals, Inc.
                        ---------------------------------
               (Exact Name of Registrant as Specified in Charter)


      Delaware                         0-28308               52-1758016
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(State or Other Jurisdiction   (Commission File Number)    (IRS Employer
      of Incorporation)                                  Identification No.)


41 University Drive, Newtown, Pennsylvania                           18940
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(Address of Principal Executive Offices)                           (Zip Code)


                                 (215) 579-7388
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                 (Registrant's telephone number, including area
                                      code)



        ----------------------------------------------------------------
          (Former Name or Former Address, if Changed Since Last Report)





ITEM 5.       OTHER EVENTS.

On July, 16, 2003, CollaGenex Pharmaceuticals, Inc., a Delaware corporation (the
"Company"),  issued  a press  release  announcing  it had  filed  and  served  a
preliminary  injunction  in the District  Court for the Eastern  District of New
York in  connection  with its  patent  infringement  litigation  against  United
Research  Laboratories/Mutual  Pharmaceutical  Company  ("Mutual").  The Company
previously announced that it had served a complaint in the same court seeking to
prevent Mutual from  introducing a 20mg tablet of  doxycycline  hyclate into the
market in the United States.

The foregoing  statements are qualified in their entirety by the Company's press
release,  a complete  copy of which is filed  herewith  as  Exhibit  99.1 and is
incorporated  herein  by  reference.  Item 7.  Financial  Statements,  Pro Forma
Financial Information and Exhibits.

     (c) Exhibits.

       Exhibit No.     Description
       -----------     ------------
          99.1         Press release of CollaGenex Pharmaceuticals, Inc., dated
                       July 16, 2003.

                                      -2-




                                   SIGNATURES
                                   -----------


     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned, hereunto duly authorized.

                        COLLAGENEX PHARMACEUTICALS, INC.



                           By:/s/ Nancy C. Broadbent
                              --------------------------------------------
                               Nancy C. Broadbent
                               Chief Financial Officer
                               (Principal Financial Officer)


Date:  July 16, 2003