EXHIBIT 10.16
                             BOSTON BIOMEDICA, INC.

                           EMPLOYEE STOCK OPTION PLAN


        1. Purpose.  The purpose of this Boston  Biomedica,  Inc. Employee Stock
Option Plan (the  "Plan") is to provide  increased  incentives  to  employees of
Boston  Biomedica,  Inc. and its Parent and  Subsidiaries,  if any (referred to,
unless  the  context  otherwise  requires,   as  the  "Corporation")  to  remain
affiliated  with the  Corporation,  to promote the success of the  Corporation's
business,  to encourage new employees to become  affiliated with the Corporation
and to associate  more  closely the  interests of such persons with those of the
Corporation  through the granting of options to acquire the capital stock of the
Corporation.

        2.  Definitions.  As used  herein,  the  following  terms  will have the
indicated meaning:

        "Board" means the "Board of Directors" of the Corporation.

        "Code"  means the Internal  Revenue  Code of 1986,  as it may be amended
from time to time.

        "Committee" means the Committee of the Board as described in Section 4.

        "Corporation" means Boston Biomedica, Inc.

        "Fair Market Value"  means,  on the date for which the Fair Market Value
is to be  determined,  the closing price of the  Corporation's  Stock on the New
York Stock Exchange,  American Stock Exchange or such other national  securities
exchange or the National  Association of Securities Dealers Automated  Quotation
System on which the Stock is then traded, or if no such price is available or if
the Stock is not then so traded, the fair market value reasonably  determined by
the Committee in good faith.

        "Incentive  Stock  Option" means any Option  issued  hereunder  which is
treated as an Incentive Stock Option under Section 422 of the Code.

        "Option" means the  contractual  right to purchase  shares of Stock upon
specified terms pursuant to this Plan.

        "Parent" has the meaning  specified for "Parent  Corporation" in Section
424(e) of the Code.

        "Permanent and Total Disability" has the meaning specified for permanent
and total disability in Section 22(e)(3) of the Code.

        "Plan" means this Boston Biomedica, Inc. Employee Stock Option Plan.






        "Employees"  means all those persons who are employed by the Corporation
for a minimum of 20 hours per week.

        "Stock" means the Common Stock, $.01 par value, of the Corporation.

        "Subsidiary" has the meaning  specified for "Subsidiary  Corporation" in
Section 424(f) of the Code.

        "Ten Percent Stockholder" means an individual who directly or indirectly
owns capital stock  possessing  more than 10% of the total combined voting power
of all classes of capital stock of the  Corporation  or any Parent or Subsidiary
at the time an Incentive Stock Option is granted under this Plan.

        3. Stock  Subject  to the Plan.  The  aggregate  number of shares of the
Corporation's  Stock  that may be  issued  and  sold  under  the  Plan  shall be
1,500,000  shares.  The shares of Stock to be issued  upon  exercise  of Options
granted under this Plan shall be made available,  at the discretion of the Board
of Directors,  from (i) authorized but unissued shares,  (ii) shares  previously
reserved  for  issuance  upon  exercise  of Options  which have  expired or been
terminated,  or (iii) treasury  shares and shares  reacquired by the Corporation
for this purpose,  including shares purchased in the open market.  If any Option
granted under this Plan shall expire or terminate for any reason  without having
been exercised in full,  the  unpurchased  shares  covered  thereby shall become
available for grant under additional  Options under the Plan so long as it shall
remain in effect.

        4.      Administration of the Plan.

        (a) The Plan shall be administered by the Committee. The Committee shall
consist of at least one member  appointed  by the Board,  and such member  shall
serve at the  pleasure  of the  Board.  The Board may from time to time  appoint
additional members of the Committee or remove members and appoint new members in
substitution for those previously appointed and fill vacancies however caused. A
majority of the Committee  shall  constitute a quorum and the acts of a majority
of the  members  present at any  meeting  at which a quorum is present  shall be
deemed the action of the Committee. At such time as any class of equity security
of the  Corporation  is  registered  pursuant  to Section  12 of the  Securities
Exchange Act of 1934, as amended (the "Act"), (i) the Committee shall consist of
at least two  members of the Board and (ii) no member of the  Committee  while a
member  thereof shall be eligible to participate in the Plan, nor may any person
be appointed to the Committee  unless he or she was not eligible to  participate
in the Plan or any other plan of the Corporation at any time within the one-year
period  immediately  prior  to  such  appointment  as  provided  in  Rule  16b-3
promulgated under the Act.

        (b) Subject to the express provisions of this Plan and provided that all
actions taken shall be consistent  with the purposes of the Plan,  the Committee
shall have full and complete authority and the sole discretion to: (i) determine
those  Employees of the  Corporation  to whom Options shall be granted under the
Plan;  (ii)  determine  the number of shares of Stock subject to and the form of
Options  to be  granted  to such  Employees;  (iii)  amend the  number of shares



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covered by and the form of the Options to be granted; (iv) determine the time or
times when Options shall be granted; (v) establish the terms and conditions upon
which Options may be exercised and/or transferred;  (vi) establish the terms and
conditions,  if any,  upon which the shares of Stock  issuable  upon exercise of
Options  may be  transferred,  including,  but not limited to the return of such
shares to the Corporation upon the occurrence of certain events; (vii) alter any
restrictions or conditions upon Options and/or the shares of Stock issuable upon
exercise of Options; and (viii) adopt rules and regulations,  establish,  define
and/or   interpret  any  other  terms  and   conditions,   and  make  all  other
determinations  (which  may be on a  case-by-case  basis)  deemed  necessary  or
desirable for the administration of the Plan.

        (c) In making its  determinations  hereunder,  the Committee  shall take
into  account  the nature of the  services  rendered  or to be  rendered  by the
Employees,  their  present  and  potential  contributions  to the success of the
Corporation,  and such other factors as the Committee, in its discretion,  shall
deem relevant in order to accomplish the purposes of the Plan.

        5. Eligibility. Options may be granted only to persons who are Employees
as defined in Section 2 of this Plan.

        6.      Terms of Options and Limitations Thereon.

        (a) General.  Any Option granted under this Plan shall be evidenced by a
written  agreement  between the  Corporation  and the Option holder and shall be
upon such terms and conditions not inconsistent  with this Plan as the Committee
may determine.  The Committee shall designate, at the time of the grant, whether
the Option is an Incentive Stock Option.  If the Option is not intended to be an
Incentive  Stock Option,  but otherwise  qualifies as an Incentive  Stock Option
under the  Code,  such  agreement  shall  include  the  following,  or a similar
statement:  "This Stock Option is not intended to be an Incentive  Stock Option,
as that term is described  in Section 422 of the Internal  Revenue Code of 1986,
as amended."

        (b)  Price.  The  price at which any  shares  of Stock may be  purchased
pursuant  to the  exercise  of an Option  shall be for any lawful  consideration
determined by the  Committee,  but not less than par value,  and, in the case of
any Incentive Stock Option,  such purchase price shall not be less than the Fair
Market  Value of the Stock on the date of the grant of the  Option  (or,  in the
case of Ten Percent  Stockholders,  110% of the Fair Market Value on such date),
without regard to any restrictions  other than those restrictions which by their
terms will never lapse.

        (c) Period of Option. Each Option granted under this Plan shall continue
in effect for such period as the  Committee  shall  determine,  provided that no
Incentive Stock Option, or installment thereof, may be exercisable subsequent to
ten years from the date of grant  (five years from the date of grant in the case
of Incentive  Stock Options  issued to Ten Percent  Stockholders).  No Incentive
Stock Option shall be exercisable  beyond three months after the date upon which
the Incentive  Stock Option holder ceases to be an employee of the  Corporation,
except that the Committee may provide in the Incentive  Stock Option that in the
event of  termination  of  employment  by reason of death or Permanent and Total
Disability  of the holder,  the  Incentive  Stock Option may be exercised by the
holder or his or her estate for a period of up


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to one year after  termination of employment.  The Committee may provide for the
termination of any Option upon  termination of the Option  holder's  affiliation
with the Corporation.

        (d) Non-Assignability. No Option or right or interest in an Option shall
be  assignable  or  transferable  by the  holder  except  by will or the laws of
descent and distribution.  During the lifetime of the holder, an Option shall be
exercisable only by him or her.

        (e) Other Restrictions.  At the discretion of the Committee, any Options
granted and the shares of Stock issuable upon exercise of Options may be subject
to restrictions on vesting or  transferability or to risk of forfeiture upon the
happening of such events as the  Committee  may  determine,  any of which may be
accelerated or waived in the Committee's sole discretion.

        7. One  Hundred  Thousand  Dollar  Limitation.  To the  extent  that the
aggregate  Fair Market Value of Stock with respect to which any incentive  stock
options  of the  Corporation  issued  under  this Plan or any other  plan of the
Corporation  (determined without regard to this Section) are exercisable for the
first time by any  holder  during  any  calendar  year  exceeds  $100,000,  such
Incentive  Stock  Options  shall be treated as Options  which are not  Incentive
Stock Options.  For the purpose of this limitation,  Options shall be taken into
account in the order  granted,  and the Committee may designate  that portion of
any  Incentive  Stock  Option  that shall be treated as not an  Incentive  Stock
Option in the event that the  provisions  of this Section  apply to a portion of
any Option, unless otherwise required by the Code or regulations of the Internal
Revenue Service. The designation described in the preceding sentence may be made
at  such  time as the  Committee  considers  appropriate,  including  after  the
issuance of the Option or at the time of its  exercise.  For the purpose of this
Section,  Fair Market Value shall be  determined  as of the time the Option with
respect to which such Stock is granted.

        8.      Exercise of Options; Payment.

        (a)  Options  may be  exercised  in whole or in part at such time and in
such manner as the  Committee  may  determine  and as shall be prescribed in the
written agreement with each holder.

        (b) The  purchase  price of shares of Stock upon  exercise  of an Option
shall be paid by the Option  holder in full upon exercise and may be paid (i) in
cash,  (ii) by delivery of shares of Stock  (valued at Fair Market  Value at the
date of purchase  of the shares of Stock  subject to the  Option),  or (iii) any
combination of cash and Stock,  as the Committee may permit.  The Committee also
may allow the cashless exercise of Options, subject to applicable law.

        9.      Stock Adjustments.

        (a) If the  Corporation is a party to any merger or  consolidation,  any
purchase or acquisition of property or stock, or any separation,  reorganization
or  liquidation,  the  Board  of  Directors  (or if the  Corporation  is not the
surviving  corporation,  the board of  directors of the  surviving  corporation)
shall  have the power to make  arrangements,  which  shall be  binding  upon


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the holders of unexpired  Options,  for the  substitution of new Options for, or
the assumption by another corporation of, any unexpired Options then outstanding
hereunder.

        (b) If by reason of recapitalization,  reclassification, stock split-up,
combination  of shares,  separation  (including  a spin-off)  or dividend on the
Stock payable in Stock,  the outstanding  shares of Stock of the Corporation are
increased or decreased  or changed into or exchanged  for a different  number or
kind of shares or other  securities of the  Corporation,  the Board of Directors
shall conclusively  determine the appropriate  adjustment in the exercise prices
of  outstanding  Options  and in the  number  and  kind of  shares  as to  which
outstanding Options shall be exercisable.

        (c) In the event of a  transaction  of the type  described in paragraphs
(a) and (b) above,  the total number of shares of Stock on which  Options may be
granted  under  this  Plan  shall  be  appropriately  adjusted  by the  Board of
Directors.

        10. No Rights  Other Than Those  Expressly  Created.  No Employee of the
Corporation  or other  person  shall  have any claim or right to be  granted  an
Option  hereunder.  Neither  this Plan nor any action taken  hereunder  shall be
construed as (i) giving any Option holder any right to be retained in the employ
of the  Corporation,  (ii) giving any Option holder an equity or interest of any
kind in any assets of the Corporation,  or (iii) creating a trust of any kind or
a  fiduciary  relationship  of any kind  between  the  Corporation  and any such
person.  As to any claim for any unpaid  amounts  under  this  Plan,  any person
having a claim for payments  shall be an unsecured  creditor.  No Option  holder
shall have any of the rights of a  stockholder  with  respect to shares of Stock
covered by an Option until such time as the Option has been exercised and shares
of Stock have been issued to such person.

        11.     Miscellaneous.

        (a) Withholding of Taxes.  Pursuant to applicable Federal,  state, local
or foreign  laws,  the  Corporation  may be required to collect  income or other
taxes upon the grant of an Option to, or exercise of an Option by, a holder. The
Corporation may require,  as a condition to the exercise of an Option,  that the
recipient pay the Corporation,  at such time as the Committee or the Corporation
determines,  the amount of any taxes which the Committee or the  Corporation may
determine  is  required  to be withheld or  collected.  In its  discretion,  the
Corporation  may  withhold  shares of Stock to be received  upon  exercise of an
Option if it deems this an  appropriate  method for  withholding  or  collecting
taxes.

        (b) Legal and Other Requirements. Upon exercise of an Option, the holder
shall be required to make such  representations  and furnish such information as
may, in the opinion of counsel for the Corporation, be appropriate to permit the
Corporation  to issue or  transfer  the shares of Stock in  compliance  with the
provisions of applicable  Federal or state securities laws. The Corporation,  in
its  discretion,  may postpone the issuance and delivery of shares of Stock upon
any  exercise  of an  Option  until  completion  of such  registration  or other
qualification  of such shares under any Federal or state laws, or stock exchange
listing, as the Corporation may consider appropriate.  The Committee may require
that prior to the issuance or transfer of Stock


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upon  exercise of an Option,  the  recipient  enter into a written  agreement to
comply with any restrictions on subsequent disposition that the Committee or the
Corporation deems necessary or advisable under any applicable law, regulation or
official  interpretation  thereof.  No  shares  of Stock  shall be  issued  upon
exercise of Options unless and until the  Corporation is satisfied,  in its sole
discretion,   that  there  has  been  compliance  with  all  legal  requirements
applicable  to the  issuance  of  such  shares.  Certificates  of  Stock  issued
hereunder may be legended to reflect such restrictions.

        (c) Indemnity. Neither the Board of Directors nor the Committee, nor any
members of either, nor any employees of the Corporation, shall be liable for any
act, omission, interpretation,  construction or determination made in good faith
in  connection  with their  responsibilities  with respect to the Plan,  and the
Corporation  hereby  agrees to indemnify  the members of the Board of Directors,
the members of the Committee, and the employees of the Corporation in respect of
any claim,  loss,  damage, or expense  (including counsel fees) arising from any
such act,  omission,  interpretation,  construction or determination to the full
extent permitted by law.

        12.     Effective Date; Amendment; Termination.

        (a) The effective date of this Plan shall be the date of adoption by the
Board of Directors;  provided, however, that the Plan is subject to the approval
of the  stockholders  at the next meeting of stockholders of the Corporation and
within twelve months from the effective date of this Plan.

        (b) The date of grant of any Option granted  hereunder shall be the date
upon  which  such  Option  shall  be  voted by the  Committee,  unless  the vote
expressly otherwise provides.

        (c) The Board of Directors of the  Corporation may at any time, and from
time to  time,  amend,  suspend  or  terminate  this  Plan in  whole or in part;
provided,  however,  that the Board of Directors may not materially increase the
benefits accruing to participants in the Plan, materially increase the number of
shares of Stock  reserved  for  purposes of this Plan other than  pursuant to an
adjustment  under  Section  9,  or  materially  modify  the  requirements  as to
eligibility for participation in this Plan without stockholder approval.

        (d) Without  amending  this Plan,  except to the extent  required by the
Code in the case of Incentive  Stock  Options,  the  Committee may modify grants
made to participants who are foreign nationals or otherwise employed outside the
United States so as to recognize differences in local law, tax policy or custom.

        (e) Except as provided herein,  no amendment,  suspension or termination
of this Plan may  affect  the  rights of any  person to whom an Option  has been
granted without such person's consent.

        (f)  Stockholder  approval  of  this  Plan  or any  amendment  requiring
stockholder  approval under paragraph (c) shall mean the affirmative  vote of at
least a majority of the shares of capital  stock present and entitled to vote at
a duly held meeting of  stockholders  unless a


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greater  vote is required by state or federal law.  Stockholder  approval may be
obtained by written consent or other means permitted by applicable state law.

        (g) This Plan shall  terminate  ten (10)  years from the  earlier of the
date of  stockholder  approval of the Plan or its effective  date, and no Option
shall be granted  under this Plan  thereafter,  but such  termination  shall not
affect the validity of Options granted prior to the date of termination.

        (h) This Plan and all Options granted hereunder shall be governed by the
law of the state in which the Corporation is incorporated.

Date of Board of Director Adoption:  March 29, 1994

Date of Stockholder Approval:  June 29, 1994

                                  A true copy.

                                  ATTEST:


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                                  Clerk