EXHIBIT 10.10



                         EXECUTIVE EMPLOYMENT AGREEMENT


         This Executive  Employment  Agreement is signed as of November 20, 1994
("Execution  Date"), but made effective as of May 5, 1993 ("Effective Date"), by
and between Jenner  Technologies,  a California  corporation (the "Company") and
Anthony E. Maida III (the "Executive").

         1. Position and Duties.  The Company hereby hires the Executive and the
Executive hereby accepts  employment as Chief Executive  Officer of the Company.
The Executive will, to the best of his ability during his employment, devote his
full time and best efforts to the performance of the duties and functions of the
position of Chief  Executive  Officer of the Company,  and in the performance of
those duties,  will comply with the policies of the Company and the direction of
the  board of  directors.  If  requested,  the  Executive  agrees  to serve as a
director of the Company without any additional compensation.

         2. Compensation.

                  (a) Salary.  The Company  agrees to pay the  Executive and the
Executive  agrees to accept as  compensation  for his  services,  a monthly base
salary of $8,333.33  payable in accordance with the Company's  standard  payroll
policy.  The first and last  payment by the  Company to the  Executive  shall be
prorated, if necessary, to reflect a commencement or termination date other than
the first or last working day of a pay period.  From time to time,  the board of
directors will consider  increases in Executive's annual rate of salary in light
of the Executive's individual performance and other relevant factors.

                  (b)  Benefits.  The  Executive  will be  entitled  to standard
vacation,   fringe  benefits  and  reimbursement  for  reasonable  out-of-pocket
expenses  in  accordance  with  the  Company's   practices   covering  executive
personnel, as such may be in effect from time to time.

         3. Proprietary  Information Agreement. In connection with the execution
of this Agreement,  the Executive  reaffirms and agrees to abide by the terms of
his Employee Proprietary  Information  Agreement with the Company (except to the
extent that such agreement references at- will employment).

         4. Terms and Termination.

                  (a) Term. Except as otherwise set forth herein, this Agreement
will terminate on November 20, 1997;  provided however that, on each anniversary
of the Execution  Date, the term of this  Agreement  shall be extended to a date
three (3) years from the date of the  respective  anniversary  date,  unless the
Company  shall  have  given  Executive  sixty  (60)  days  notice  prior to such
anniversary  date of its  intent not to renew the  Agreement.  The final date of
termination of this Agreement is referred to herein as the "Termination Date."

                  (b) Termination For Cause. This Agreement may be terminated by
the  Company at any time for cause (as  defined  below)  without  any  severance
obligation  on the part of the  Company.  For purposes of this  Agreement,  "for
cause" shall include (i) acts of moral turpitude by the


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Executive,  (ii) willful or habitual  neglect of Executive's  obligations  under
this Agreement,  (iii) an act of theft or dishonesty involving the Company, (iv)
the wrongful  disclosure of trade secrets,  (v) any other intentional  action by
Executive  that  causes  material  damage to the Company or its  relations  with
customers,  suppliers,  employees  or  consultants,  or (vi)  conviction  of the
Executive of a felony.

                  (c)   Termination   Without  Cause.   This  Agreement  may  be
terminated by the Company at any time without  cause;  provided that the Company
shall pay to Executive as a severance payment (i) an amount equal to Executive's
remaining  salary  payable  under  this  Agreement  through  and  including  the
Termination  Date computed at Executive's  then applicable  monthly base salary,
(ii) any bonus which has not been paid at the time of termination, and (iii) any
vacation,  sick leave or other accrued  benefits  payable in accordance with the
Company's policies then in effect. The payment to the Executive of the severance
payment  described in this  Section  4(c) and the vesting of stock  described in
Section  4(e) below  will  discharge  all of the  Company's  obligations  to the
Executive.

                  (d) Termination in the Event of Bankruptcy.  In the event that
the Company is the subject of, (i) any bankruptcy  proceeding,  (ii)  assignment
for the benefit of creditors,  (iii) a general cessation of operations,  or (iv)
any other determination that the Company is insolvent and unable to continue its
normal  business  functions and  activities  (individually  and/or  collectively
"Bankruptcy");  and  such  Bankruptcy  is the  cause  for  termination  of  this
Agreement,  then the  Company  shall pay to  Executive  $50,000  as a  severance
payment, to the greatest extent such payment is allowed by applicable law and/or
any court of competent jurisdiction.

                  (e)  Termination  by Executive;  Death.  This Agreement may be
terminated  by the Executive at any time upon 30 days written  notice,  in which
case the  Company  shall  have no  severance  obligation  to the  Executive.  If
Executive dies before the end of the term of this Agreement,  Executive's estate
shall be entitled to receive (i) an amount equal to Executive's remaining salary
payable under this Agreement through and including the Termination Date computed
at Executive's then applicable monthly base salary, (ii) any bonus which has not
been paid at the time of death,  and (iii) any  vacation,  sick  leave and other
accrued  benefits  payable in  accordance  with the  Company's  policies then in
effect.

                  (f)  Status as an  Employee;  Vesting  of  Stock.  Executive's
status as an employee of the Company  will be deemed to cease on the date of any
termination of employment as provided above. In the event that this Agreement is
terminated by the Company without cause (as provided in Section 4(c) above),  or
the  Executive  dies or  becomes  disabled  (as such terms is defined in Section
22(e)(3) of the Internal Revenue Code of 1986, as amended) before the end of the
term of this  Agreement  (as  provided in the second  sentence  of Section  4(e)
above), then 100% of the shares subject to the Stock Purchase Agreement dated as
of December 10, 1992 between the Company and the Executive (the "Stock  Purchase
Agreement")  shall be released from the Repurchase Option set forth in Section 4
of such Stock Purchase Agreement.



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         5. Conflicting  Agreements.  The Executive represents and warrants that
he is free to enter  into  this  Agreement  and  that  there  are no  employment
contracts or restrictive  covenants  preventing  full  performance of his duties
hereunder.

         6.  Withholding.  All amounts payable to Executive under this Agreement
shall be subject to applicable  withholding  by the Company for taxes payable by
the Executive.

         7. Miscellaneous.

                  (a)  Assignment.  This Agreement is predicated upon the unique
abilities and personal  relationship of Executive and the Company.  Accordingly,
Executive may not assign this Agreement or any of his rights  hereunder  without
the express  written  consent of the Company.  This  Agreement will inure to the
benefit of and will be binding upon the successors and assigns of the Company.

                  (b) Entire Agreement;  Amendment.  This Agreement contains the
entire  agreement of the parties,  and may not be changed orally,  but only by a
subsequent  writing signed by the party against whom  enforcement of such change
is sought.

                  (c) Prior Agreements;  Waiver.  This Agreement  supersedes any
prior agreement  between the parties related to the subject matter hereof. It is
agreed  that a waiver  by  either  party of a breach  of any  provision  of this
Agreement shall not operate or be construed as a waiver of any subsequent breach
by the same party.

                  (d)  Severability.  In  case  one or  more  of the  provisions
contained in this Agreement shall for any reason be held to be invalid,  illegal
or unenforceable in any respect, such invalidity, illegality or unenforceability
shall not affect any other  provisions  of this  Agreement  but such  provisions
shall be deemed  deleted and such deletion  shall not affect the validity of any
other provision of this Agreement.

                  (e)  Governing  Law. This  Agreement  shall be governed by and
construed according to the internal laws of the State of California. The federal
and state courts of the state of California shall have exclusive jurisdiction to
adjudicate any dispute rising out of this Agreement.

         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
executed as of the day and year first above written.

JENNER TECHNOLOGIES                           ANTHONY E. MAIDA III


By:/s/ LYNN SPITLER                           /s/ ANTHONY E. MAIDA
   --------------------------                 --------------------------
Title:Chairman
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