EXHIBIT 4.6

                              ______________, 1997
ConSyGen, Inc.
c/o John G. Nossiff, Jr., Esq.
Brown, Rudnick, Freed & Gesmer
One Financial Center
Boston, MA  02111

ATTN:  Ronald I. Bishop, President and Chief Executive Officer

         Re:      ConSyGen, Inc.
                  ------------------

Ladies and Gentlemen:

         The  undersigned  hereby  subscribes  to the immediate  acquisition  of
_______ shares of Common Stock, $.003 par value (the "Securities"), of ConSyGen,
Inc., a Texas corporation (the "Company"),  at a per share price of U.S. $______
for aggregate  consideration of U.S.  $___________ The undersigned is delivering
herewith  to the  Escrow  Agent  (defined  below)  at  the  above  address  U.S.
$__________  by certified  check or federal funds wire transfer to the following
account:

         BANK:             FLEET PRIVATE BANKING
         ABA:              011000138
         SWIFT CODE:       FLTBUS3B  (For international wires only)
         CITY:             BOSTON
         STATE:            MASSACHUSETTS
         ACCOUNT #:        93568 68063
         ACCOUNT NAME:     BROWN, RUDNICK, FREED & GESMER, CLIENT
                           TRUST FUND
                           ATTN:  JOHN G. NOSSIFF, JR.

         ORIGINATION OF FUNDS:

         BANK:_______________________________________________

         CITY:_______________________________________________

         STATE:______________________________________________

         AMOUNT OF FUNDS WIRED:______________________________

GIVE FOLLOWING INSTRUCTIONS TO ORIGINATING BANK:
- ------------------------------------------------

         Originating  Bank should instruct Fleet Private Banking to notify BRF&G
Accounting Department upon receipt of the funds - Use Code CSGI.










         There  is no  minimum  offering  amount.  Pending  acceptance  of  this
subscription,  the  funds  delivered  herewith  will be held in escrow by Brown,
Rudnick,  Freed & Gesmer,  counsel to the Company  (the "Escrow  Agent"),  in an
interest-bearing account. In the event the funds are not received by the Closing
Date (August 29, 1997,  unless  extended by the Company) or the Company  rejects
this  subscription  (which  the  Company  reserves  the  right to do in its sole
discretion), the Company shall cause the Escrow Agent to return the funds to the
subscriber with interest earned thereon.  Upon the Company's  acceptance of this
subscription, the Company shall deliver the Securities to the undersigned at the
address  indicated  below and the Escrow  Agent  shall  deliver the funds to the
Company.  The  Escrow  Agent  shall  have no  liability  to the  undersigned  in
connection with acting as Escrow Agent,  except for acts  constituting  fraud or
willful misconduct.

         In  connection  with the purchase of the  Securities,  the  undersigned
acknowledges, warrants and represents to the Company as follows:

         1. The  undersigned  is acquiring the Securities for investment for its
own account and without the intention of participating,  directly or indirectly,
in a  distribution  of the  Securities,  and not  with a view to  resale  or any
distribution of the Securities, or any portion thereof.

         2. The  undersigned  has  knowledge  and  experience  in financial  and
business matters and has consulted with its own professional  representatives as
it has  considered  appropriate  to assist in evaluating the merits and risks of
this  investment.  The  undersigned  has been  provided  with and has  carefully
reviewed the ConSyGen,  Inc.  Disclosure  Memorandum  dated August 26, 1997 (the
"Company Information").  The undersigned has had access to and an opportunity to
question the officers of the Company,  or persons  acting on their behalf,  with
respect to material  information  about the Company and, in connection  with its
evaluation of this investment,  has, to the best of its knowledge,  received all
information  and data with  respect  to the  Company  that the  undersigned  has
requested. The undersigned is acquiring the Securities based solely upon (1) the
Company Information;  and (2) its independent examination and judgment as to the
prospects of the Company.

         3. The  Securities  were not  offered  to the  undersigned  by means of
publicly disseminated advertisements or sales literature.

         4. The undersigned acknowledges that an investment in the Securities is
speculative  and the  undersigned may have to continue to bear the economic risk
of the investment in the Securities for an indefinite  period.  The  undersigned
acknowledges  that the  Securities  are being  sold to the  undersigned  without
registration  under any state or  federal  law  requiring  the  registration  of
securities for sale, and accordingly will constitute "restricted  securities" as
defined  in  Rule  144  of  the   Securities   and  Exchange   Commission.   The
transferability  of the Securities is therefor  restricted by applicable  United
States Federal and state securities laws and may be restricted under the laws of
other jurisdictions.

         5. The undersigned is an "accredited  investor" as such term is defined
in Appendix A.

         6.  In  consideration  of the  acceptance  of  this  subscription,  the
undersigned  agrees that the  Securities  will not be offered for sale,  sold or
transferred  by  the  undersigned  other  than






pursuant to (i) an effective  registration  under the Securities Act of 1933, as
amended ("the Act"), an exemption  available under the Act or a transaction that
is otherwise  in  compliance  with the Act;  and (ii) an effective  registration
under the  securities law of any state or other  jurisdiction  applicable to the
transaction,  an exemption  available under such laws, or a transaction  that is
otherwise in compliance with such laws.

         7. The undersigned understands that no U.S. federal or state agency has
passed  upon  the  offering  of  the  Securities  or has  made  any  finding  or
determination as to the fairness of any investment in the Securities.

         The  undersigned  agrees to indemnify and hold harmless the Company and
its  officers,  directors,  employees  and agents  from and  against any and all
costs,  liabilities and expenses  (including  attorneys' fees) arising out of or
related in any way to any breach of any  representation  or  warranty  contained
herein.

         The Company agrees to file,  within 45 days of Closing,  a Registration
Statement on Form S-1 registering the shares for resale by the  undersigned.  At
the end of each 30 day  period,  after  the  expiration  of such 45 day  period,
during which the Registration Statement is not filed, a fee shall be paid to the
undersigned  equal to two (2%)  percent of the amount  invested,  but in no case
shall such fee exceed ten (10%) percent of the amount invested. Any fee shall be
payable in shares of common stock of the Company.  The number of shares shall be
determined  by dividing the dollar  amount of the fee,  determined in accordance
herewith, by $_______ (the per share purchase price hereunder). Any fee shall be
paid with shares within ten (10) days of the due date thereof.

ACCEPTANCE OF SUBSCRIPTION                      SUBSCRIBER

ConSyGen, Inc.                                  ________________________________
                                                Name:  _________________________
                                                Address:  ______________________

By:  /s/Ronald I. Bishop                                  ______________________
     ---------------------                                ______________________
     Ronald I. Bishop, President

Dated:
         -----------------









                                   APPENDIX A

An "Accredited Investor" within the meaning of Regulation D under the Securities
Act of 1933 includes the following:

Organizations
- -------------

        (1) A bank as defined in section  3(a)(2) of the Act, or any savings and
loan  association or other  institution as defined in section  3(a)(5)(A) of the
Act, whether acting in its individual or fiduciary capacity;  a broker or dealer
registered  pursuant  to  section  15 of the  Securities  Exchange  Act of 1934;
insurance company as defined in section 2(13) of the Act; an investment  company
registered  under the Investment  Company Act of 1940 or a business  development
company as defined in section 2(a)(48) of that act; a Small Business  Investment
Company licensed by the U.S. Small Business  Administration under section 301(c)
or (d) of the Small Business  Investment  Act of 1958; an employee  benefit plan
within the meaning of Title I of the Employee  Retirement Income Security Act of
1974,  if the  investment  decision is made by a plan  fiduciary,  as defined in
section 3(21) of such act, which is either a bank, savings and loan association,
insurance company, or registered  investment adviser, or if the employee benefit
plan has total assets in excess of $5,000,000 or, if a self-directed  plan, with
investment decisions made solely by persons that are accredited investors.

        (2) A  private  business  development  company  as  defined  in  Section
202(a)(22) of the Investment Advisers Act of 1940.

        (3) A trust (i) with  total  assets in  excess of  $5,000,000,  (ii) not
formed for the  specific  purpose  of  acquiring  the  Securities,  (iii)  whose
purchase  is  directed  by a person  who,  either  alone  or with his  purchaser
representative,  has such  knowledge  and  experience  in financial and business
matters  that he is capable of  evaluating  the merits and risks of the proposed
investment.

        (4) A  corporation,  business  trust,  partnership,  or an  organization
described  in section  501(c)(3)  of the Internal  Revenue  Code,  which was not
formed for the specific purpose of acquiring the Securities, and which has total
assets in excess of $5,000,000.

Individuals
- -----------

        (5)  Individuals  with  income from all sources for each of the last two
full  calendar  years whose  reasonably  expected  income for this calendar year
exceeds either of:

               (i)      $200,000 individual income; or
               (ii)     $300,000 joint income with spouse.

NOTE:  Your  "income" for a particular  year may be calculated by adding to your
adjusted  gross  income as  calculated  for  Federal  income  tax  purposes  any
deduction for long term capital  gains,  any deduction for depletion  allowance,
any exclusion for tax exempt interest and any losses of a partnership  allocated
to you as a partner.

        (6) Individuals  with net worth as of the date hereof  (individually  or
jointly  with  your  spouse),  including  the  value of home,  furnishings,  and
automobiles, in excess of $1,000,000.

        (7) Directors, executive officers or general partners of the Issuer.





                             SCHEDULE TO EXHIBIT 4.6


                                                                  TOTAL
NO. OF SHARES       PRICE PER                                     SUBSCRIPTION
SUBSCRIBED          SHARE             DATE ACCEPTED               PRICE


15,000              $6.75             9/19/97                     $101,250


20,000              $5.50             9/19/97                     $110,000

 2,000              $5.00             9/19/97                     $ 10,000



15,000              $6.75             9/19/97                     $101,250

50,000              $5.60             8/27/97                     $280,000

50,000              $5.60             8/27/97                     $280,000