UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549



                                    FORM 8-K

                                 CURRENT REPORT

                         Pursuant to Section 13 or 15(d)
                     of the Securities Exchange Act of 1934


Date of Report (Date of earliest event reported): October 31, 2001



                                  OXIGENE, INC.
                                  -------------
             (Exact name of registrant as specified in its charter)


   Delaware                       0-21990                      13-3679168
---------------                -------------              --------------------
(State or other                (Commission                (IRS Employer
jurisdiction of                 File Number)               Identification No.)
incorporation)



                               321 Arsenal Street
                               ------------------
                         Watertown, Massachusetts         02472
               ---------------------------------------------------
               (Address of principal executive offices) (Zip Code)


Registrant's telephone number, including area code: (617) 673-7800


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Item 5. Other Events and Regulation FD Disclosure.

On October 31, 2001, the Registrant  issued a press release,  a copy of which is
attached  hereto as Exhibit 99.1,  announcing  that it has completed the Phase I
U.S.  clinical  trial  of  its  novel  anti-tumor   vascular   targeting  agent,
Combretastatin A4 Prodrug (CA4P). The trial generated statistically  significant
findings  demonstrating  CA4P's ability to  successfully  reduce blood flow that
feeds malignant tumors.  CA4P is the first vascular  targeting drug to be tested
in a human trial in the United States.

Item 7. Financial Statements and Exhibits.

(c) The following exhibits are filed with this report:

Exhibit Number                        Description
--------------                        -----------

    99.1            Press release of Registrant dated October 31, 2001.

    99.2            Transcript of conference call conducted by Registrant on
                    November 1, 2001.


Item 9. Regulation FD Disclosure.

On November 1, 2001,  the  Registrant  held a conference  call (the  "Conference
Call") to discuss and  comment on the  completion  of the Phase I U.S.  clinical
trial of its  novel  anti-tumor  vascular  targeting  agent,  Combretastatin  A4
Prodrug  (CA4P).  A  transcript  of the  Conference  Call is attached  hereto as
Exhibit 99.2.



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                                   SIGNATURES
                                   ----------

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


                                  OXIGENE, INC.
                                  -------------
                                  (Registrant)



Date: November 5, 2001             By: /s/  Frederick Driscoll
                                       -----------------------
                                   Name:    Frederick Driscoll
                                   Title:   President of Operations and Finance




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                                  EXHIBIT INDEX
                                  -------------

Exhibit Number                           Description
--------------                           -----------

    99.1              Press release of Registrant dated October 31, 2001.

    99.2              Transcript of conference call conducted by Registrant on
                      November 1, 2001.



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