Exhibit 10.19


                                    Addendum


This Addendum is made the 23rd day of April 2002 by and between:

     (1)  B  Omentum  Consulting  AB, a company  incorporated  under the laws of
          Sweden  with  corp.  reg.  no.  556245-3778,  Klovervagen  6,  133  36
          Saltsjobaden,  Sweden  (hereinafter  referred to as "the Consultant");
          and

     (2)  OXiGENE  EUROPE  AB, a company  incorporated  under the laws of Sweden
          with corp. reg. no. 556503-6638.  Box 55610, 102 14 Stockholm,  Sweden
          (hereinafter referred to as "the Company").

     (1)  and (2) hereinafter collectively referred to as "the Parties".

                                   WITNESSETH

     WHEREAS the Parties entered into a Consultant Agreement on 9 October 1995,
as amended by addendums on 1 March 1996, 1 March 1997, 1 July 1999 and May 2001
(hereinafter "the Agreement");

     WHEREAS the Company is a wholly owned subsidiary of Oxigene Inc. and, thus,
all the Company's activities are to the benefit of Oxigene Inc.

     WHEREAS the management of Oxigene Inc. is currently reviewing the
possibility of downsizing the administrative structures of the Oxigene group of
companies and in this connection is considering whether it be possible to bring
to an end the activities of the Company;

     WHEREAS  the  Parties  wish for the  Agreement  to be  amended  in  certain
respects;

     NOW THEREFORE, the Parties to this Addendum (hereinafter "the Addendum")
hereby agree as follows:

1. Definitions and Interpretation

     1.1 Terms defined in the Agreement shall have the same respective meanings
in this Addendum unless the context otherwise requires.

     1.2 Subject to the provisions of this Addendum:

     -    the Agreement shall remain in full force and effect and shall be read
          and construed as one document with this Addendum;

     -    nothing in this Addendum shall constitute a waiver or release of any
          rights under the Agreement, or otherwise prejudice any tight or remedy
          either of the Parties have under the Agreement.

2. Addendum to the Agreement

     This Addendum shall take effect from 1 July, 2002 (hereinafter "the
Effective Date").

3. Amendments to the Agreement

     3.1 As from the Effective Date, it is understood and agreed that the
Agreement shall be amended as follows:

     3.1.1 The Consulting Term shall run through 30 June 2004.

     3.1.2 The Company may not terminate the Consulting Term prior to 1 July
2003. Following this date, the Consulting Term may be terminated by the Company
subject to a six month notice period. Notice shall be given in writing and
Compensation shall be paid during such period in the amounts specified in the
Agreement and this Addendum.

     3.1.3 The Annual Compensation is amended to US$ 150,000 per annum. The
Compensation shall be paid monthly in advance (US$ 12,500 per month).

4 Discontinuance of the Operations of the Company

     It is hereby understood and agreed that in the event that Oxigene Inc.
should decide to discontinue the activities of the Company, Oxigene Inc. shall
irrevocably and unconditionally assume in full all past and fu'1ute obligations
of the Company hereunder and the Consultant shall accordingly in such case
perform its services to Oxigene Inc.

     This Addendum has been executed on the date first written above in two
counterparts of which the Parties have taken one each.

The Company                                            The Consultant

OXiGENE Europe AB                                      B Omentum Consulting AB

Accepted and approved:

OXiGENE Inc.





                                 ADDENDUM TO THE
                              CONSULTING AGREEMENT
                               OF OCTOBER 9, 1995
- --------------------------------------------------------------------------------

This Addendum to the Consulting Agreement of October 9, 1995, is made on May __,
2001 by and between OXiGENE, Europe AB, Reg. No. 556503-6638 (the "Company") and
B. Omentum Consulting AB, Reg. No. 556245-3778 (the  "Consultant").  The parties
in this Agreement are jointly referred to as the "Parties".

Whereas, the Parties have entered into a Consulting Agreement,  dated October 9,
1995 and amendments  hereto dated July 1, 1999, March 1, 1996 and March 1, 1997;
and

Whereas,  the  Parties  have  agreed  upon a  reduction  of the  present  Annual
Compensation of $75,000 per annum to $50,000 per annum due to the decreased need
of the Consultants services.

Now therefore the Parties agree as follows:

1.   The annual Compensation  according to Section 2 ("Annual  Compensation") in
     the Consulting Agreement is amended to $50,000.00 per annum

2.   This addendum shall enter into effect from July 1, 2001

3.   Subject to the addendum herein the Consulting  Agreement and the amendments
     hereto shall in all other  respects be  unchanged  and remain in full force
     and effect

This  Addendum has been executed in two (2)  originals,  of which each Party has
retained one.

The Company                                 The Consultant

OXiGENE, EUROPE AB                          B. OMENTUM CONSULTING AB



/s/ Frederick Driscoll                      /s/ Bjorn Nordenvall
- ------------------------------------        ------------------------------------
                                            Bjorn Nordenvall





                        AMENDMENT TO CONSULTING AGREEMENT

This amendment is dated a of this 1st day of July, 1999, and is made and entered
into by and between  OXiGENE Europe AB,  Company  registration  No.  556503-6638
("the  Company"),  and B. Omentum  Consulting  AB,  Company  registration  No. 5
56245-3778 ("the Consultant).

WHEREAS,  the parties  have entered  into a  Consulting  Agreement  dated 9th of
October 1995 ("the  Consulting  Agreement")  and  Amendments  to the  Consulting
Agreement dated 1st March 1996 and 1st of October 1997 ("the Amendments") and

WHEREAS,  the Company  during the spring 1999 has wound up its  business in Lund
regarding testing of pharmaceutical  products and has downsized said area of its
business in general, leading to a substantially decreased need for utilizing the
Consultants services regarding testing of pharmaceutical products.

NOW, THEREFORE the parties agree as follows:

- -    Section 2 ("Annual Compensation") of the Consulting Agreement is amended by
     replacing "$ 250,000 per annum" with "$ 75,000 per annum").

In all other aspects,  the Consulting  Agreement as previously  amended shall be
unchanged and remain in full force and effect.

This  Amendment has been drawn in to originals,  of which the parties have taken
one each.

OXiGENE EUROPE AB                           B. OMENTUM CONSULTING AB



/s/ Bo Haglund                              /s/ Bjorn Nordenvall
- ------------------------------------        ------------------------------------
    Bo Haglund                                  Bjorn Nordenvall




                       AMENDMENT TO CONSULTING AGREEMENT

This  amendment  is  dated as of this 1st day of  March,  1997,  and is made and
entered into by and between  OXiGENE  Europe AB, a corporation  with  registered
office at  Scheelevagen  17, SE-223 70 Lund,  Sweden  ("Company") and B. Omentum
Consulting AB, company registration No. 556245-3778 ("Consultant").

WHEREAS,  the parties  entered into a Consulting  Agreement dated 9th of October
1995  ("Consulting  Agreement") and Amendment to Consulting  Agreement dated 1st
day of March  1996  ("Amendment");  since  then the  Company's  activities  have
expanded  substantially and therefore the Company wishes to hire Consultant to a
greater extent than was foreseen at that time.

NOW, THEREFORE the parties agree as follows:

- -    Section 2 ("Annual Compensation") of the Consulting Agreement is amended by
     replacing "$ 200,000 per annum" with "$250,000 per annum".

In all other respects, the Consulting Agreement shall be unchanged and remain in
full force and effect.

This  amendment  has been executed in two  counterparts  of which each party has
taken one.


B. OMENTUM CONSULTING AB                                OXiGENE EUROPE AB


/s/ Bjorn Nordenvall                                    /s/ Bo Haglund
- --------------------                                    --------------
    Bjorn Nordenvall                                        Bo Haglund




                       AMENDMENT TO CONSULTING AGREEMENT
- --------------------------------------------------------------------------------

This  amendment  is  dated as of this  1st day of  March  1996,  and is made and
entered into by and between  Oxygen Europe AB, a  corporation  with a registered
office at  Scheelevagen  17, S-223 70 Lund,  Sweden  ("Company")  and B. Omentum
Consulting AB, company registration No. 556245-3778 ("Consultant").

WHEREAS,  the parties  entered into a Consulting  Agreement dated 9th of October
1995 ("Consulting Agreement"); since then the Company's activities have expanded
substantially  and  therefore  the Company  wishes to hire the  Consultant  to a
greater extent than was foreseen at that time.

NOW, THEREFORE the parties agree as follows:

1.   Section 1 ("Term") of the Consulting Agreement is amended by deleting "June
     2, 1995" and all words thereafter following and replacing it with "March 1,
     1996".

2.   Section 2 ("Annual Compensation") of the Consulting Agreement is amended by
     replacing "$ 50,000 per annum" with "$ 200,000 per annum".

3.   Section  4  ("Termination")  of the  Consulting  Agreement  is  amended  by
     deleting  the words "Prior to the  expiration  of the  currently  scheduled
     Consulting Term" and replacing "90 days" with "30 days".

     Said Section 4 is further amended by adding the words "However, such notice
     may not be given before July 1, 1996".

4.   In all other  respects,  the  Consulting  Agreement  shall be unchanged and
     remain in full force and effect.

This  Amendment  has been executed in two  counterparts  of which each party has
taken one.


B. OMENTUM CONSULTING AB                                OXiGENE EUROPE AB

/s/ Bjorn Nordenvall                                    /s/ Claus Moller
- --------------------                                    ----------------
    Bjorn Nordenvall                                        Claus Moller


                                                        /s/ Ronald W. Pero
                                                        ------------------
                                                            Ronald W. Pero


                                                        /s/ Bjorn Nordenvall
                                                        --------------------
                                                            Bjorn Nordenvall