Securities and Exchange Commission

                             Washington, D.C. 20549


                                    Form 10-Q


              [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                  For the quarterly period ended March 31, 1999

             [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

         For the transition period from _____________ to _______________

                         Commission File Number 0-21021


                            Enterprise Bancorp, Inc.
             (Exact name of registrant as specified in its charter)


               Massachusetts                              04-3308902
       (State or other jurisdiction                      (IRS Employer
    of incorporation or organization)                 Identification No.)

               222 Merrimack Street, Lowell, Massachusetts,    01852

                (Address of principal executive offices)    (Zip code)

                                 (978) 459-9000
                         (Registrant's telephone number)

Indicate by check mark whether the registrant (1) has filed all reports required
to be  filed by  Section  13 or 15(d) of the  Exchange  Act of 1934  during  the
preceding 12 months (or for such shorter period that the registrant was required
to file such reports),  and (2) has been subject to such filing requirements for
the past 90 days. Yes ..X.... No......

Indicate the number of shares  outstanding  of each of the  issuer's  classes of
common stock, as of the latest practicable date:

April 30, 1999 Common Stock - Par Value $0.01, 3,169,634 shares outstanding




                                     ENTERPRISE BANCORP, INC.
                                              INDEX
                                                                                       Page Number
                                                                                     
           Cover Page                                                                        1

           Index                                                                             2

                                  PART I - FINANCIAL INFORMATION
Item 1     Financial Statements of Enterprise Bancorp, Inc.

                  Consolidated Balance Sheets - March 31, 1999 and December 31, 1998         3

                  Consolidated Statements of Income -
                  Three months ended March 31, 1999 and 1998                                 4

                  Consolidated Statements of Changes in Stockholders' Equity -               5
                  Three months ended March 31, 1999

                  Consolidated Statements of Cash Flows -
                  Three months ended March 31, 1999 and 1998                                 6

                  Notes to Financial Statements                                              7

Item 2     Management's Discussion and
           Analysis of Financial Condition and Results of Operations                         8

Item 3     Quantitative and Qualitative Disclosures About Market Risk                       16

                                   PART II - OTHER INFORMATION
Item 1     Legal Proceedings                                                                17 

Item 2     Changes in Securities and Use of Proceeds                                        17

Item 3     Defaults upon Senior Securities                                                  17

Item 4     Submission of Matters to a Vote of Security Holders                              17

Item 5     Other Information                                                                17 
                                                                                             
Item 6     Exhibits and Reports on Form 8-K                                                 17

           Signature Page                                                                   18

                SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS
This report contains certain  "forward-looking  statements" including statements
concerning plans,  objectives,  future events or performance and assumptions and
other statements which are other than statements of historical fact.  Enterprise
Bancorp,  Inc.  (the  "company")  wishes to caution  readers that the  following
important  factors,  among  others,  may have  affected  and could in the future
affect  the  company's  results  and  could  cause  the  company's  results  for
subsequent   periods  to  differ   materially   from  those   expressed  in  any
forward-looking  statement  made  herein:  (i) the effect of changes in laws and
regulations,  including  federal and state  banking laws and  regulations,  with
which the company or its subsidiaries  must comply,  and the associated costs of
compliance with such laws and regulations  either  currently or in the future as
applicable;  (ii) the effect of changes in accounting policies and practices, as
may be adopted by the regulatory agencies as well as by the Financial Accounting
Standards  Board, or of changes in the company's  organization,  compensation or
benefit plans; (iii) the effect on the company's competitive position within its
market area of the increasing  competition from larger regional and out-of-state
banking  organizations  as well  as  non-bank  providers  of  various  financial
services;  (iv) the  effect of  changes  in  interest  rates;  (v) the effect of
changes in the business  cycle and downturns in the local,  regional or national
economies;  and (vi) the potential  for the company to materially  underestimate
the cost to be incurred  and/or the time  required in  connection  with  systems
preparation for Year 2000 compliance.

                                       2



                                      ENTERPRISE BANCORP, INC.

                                     Consolidated Balance Sheets


                                                                      March 31,        December 31,
                                                                        1999               1998
($ in thousands)                                                     (Unaudited)        (Audited)         
                                                                     -----------       ------------         
                                                                                  
        Assets

Cash and cash equivalents                                             $ 15,049            19,668  
Daily federal funds sold                                                10,100             6,255
Investment securities at fair value                                    114,733           114,659
Loans, less allowance for loan losses of $5,416                                         
   at March 31, 1999 and  $5,234 December 31, 1998                     216,397           209,978
Premises and equipment                                                   4,752             4,272
Accrued interest receivable                                              2,552             2,424
Prepaid expenses and other assets                                          990               863
Income taxes receivable                                                   --                 271
Real estate acquired by foreclosure                                        304               304
Deferred income taxes, net                                               2,161             1,787
                                                                      --------          --------
                                                                                        
               Total assets                                           $367,038           360,481
                                                                      ========          ========
                                                                                        
        Liabilities and Stockholders' Equity                                            
                                                                                        
Deposits                                                              $320,689           317,666
Short-term borrowings                                                   15,871            12,085
Escrow deposits of borrowers                                               831               687
Income taxes payable                                                        88              --
Accrued expenses and other liabilities                                   1,353             2,222
Accrued interest payable                                                   629               623
                                                                      --------          --------
                                                                                        
               Total liabilities                                       339,461           333,283
                                                                      --------          --------
                                                                                        
Stockholders' equity:                                                                   
Preferred stock, $.01 par value; 1,000,000 shares                                       
        authorized, no shares issued at March 31, 1999                    --                --
Common stock $.01 par value; 5,000,000  shares authorized,                              
        3,169,634 and 3,167,684  shares issued and                                      
        outstanding at March 31, 1999 and December 31, 1998,                            
        respectively                                                        32                32
Additional paid-in capital                                              15,571            15,560
Retained earnings                                                       11,571            10,610
Accumulated other comprehensive income                                     403               996
                                                                      --------          --------
                                                                                        
               Total stockholders' equity                               27,577            27,198
                                                                      --------          --------
                                                                                        
               Total liabilities and stockholders' equity             $367,038           360,481
                                                                      ========          ========

                                                                       

                                                 3



                                         ENTERPRISE BANCORP, INC.

                                     Consolidated Statements of Income

                                Three months ended March 31, 1999 and 1998

                                                                             March 31,         March 31,
                                                                               1999              1998
($ in thousands, except per share data)                                    (Unaudited)        (Unaudited)       
                                                                           -----------       ------------
                                                                                       
Interest and dividend income:
     Loans                                                                 $    4,774              4,331
     Investment securities                                                      1,712              1,713
     Federal funds sold                                                            44                 24
                                                                           ----------         ----------
               Total interest income                                            6,530              6,068
                                                                           ----------         ----------            
Interest expense:                                                                            
     Deposits                                                                   2,398              2,259
     Borrowed funds                                                               152                169
                                                                           ----------         ----------
               Total interest expense                                           2,550              2,428
                                                                           ----------         ----------
                                                                                             
               Net interest income                                              3,980              3,640
                                                                                             
Provision for loan losses                                                         135                 90
                                                                           ----------         ----------
               Net interest income after provision for loan losses              3,845              3,550
                                                                           ----------         ----------
Non-interest income:                                                                         
     Deposit service fees                                                         205                219
     Trust fees                                                                   285                237
     Net gain on sales of loans                                                    54                 19
     Net gain on sales of investments                                            --                   71
     Other income                                                                  78                 84
                                                                           ----------         ----------
                                                                                             
               Total non-interest income                                          622                630
                                                                           ----------         ----------
Non-interest expense:                                                                        
     Salaries and employee benefits                                             1,873              1,678
     Occupancy expenses                                                           577                555
     Advertising and public relations                                             124                106
     Audit, legal and other professional fees                                     120                126
     Trust professional and custodial expenses                                     67                 74
     Office and data processing supplies                                           61                 93
     Other operating expenses                                                     286                300
                                                                           ----------         ----------
               Total non-interest expense                                       3,108              2,932
                                                                           ----------         ----------
                                                                                             
Income before income taxes                                                      1,359              1,248
Income tax expense                                                                398                445
                                                                           ----------         ----------
               Net income                                                  $      961                803
                                                                           ==========         ==========
                                                                                             
Basic earnings per average common share outstanding                        $     0.30               0.25
                                                                           ==========         ==========
                                                                                             
Diluted earnings per average common share outstanding                      $     0.29               0.24
                                                                           ==========         ==========
                                                                                             
Basic weighted average common shares outstanding                            3,168,761          3,160,434
                                                                           ==========         ==========
                                                                                             
Diluted weighted average common shares outstanding                          3,331,050          3,288,208
                                                                           ==========         ==========


                                                     4



                                                      ENTERPRISE BANCORP, INC.

                                     Consolidated Statements of Changes in Stockholders' Equity

                                                  Three months ended March 31, 1999


                                                                                                                       
                                                      Common Stock        Additional              Comprehensive Income      Total   
                                                 ---------------------     Paid-in     Retained   -------------------- Stockholders'
($ in thousands)                                    Shares      Amount     Capital     Earnings   Period   Accumulated     Equity  
                                                 -----------   -------    --------     --------   -------  ----------- -------------
                                                                                                          


Balance at December 31, 1998                       3,167,684    $   32    $ 15,560     $ 10,610                $  996      $ 27,198

Comprehensive income
    Net income                                                                              961    $  961                       961
    Unrealized losses on securities, 
      net of reclassification                                                                        (593)       (593)         (593)
                                                                                                   ------
Total comprehensive income, net of tax                                                             $  368
                                                                                                   ======

Stock options exercised                                1,950        --          11                                               11
                                                   ---------     -----    --------     --------                ------      --------

Balance at March 31, 1999                          3,169,634     $  32    $ 15,571     $ 11,571                $  403      $ 27,577
                                                   =========     =====    ========     ========                ======      ========


Disclosure of reclassification amount:
Gross unrealized holding losses arising during the period                                          $ (955)
Less: tax effect                                                                                      362  
                                                                                                   ------
Unrealized holding losses, net of tax                                                                (593)
                                                                                                   ------
Less: reclassification adjustment for gains/(losses) included
    in net income (net of $  0 tax)                                                                    -- 
                                                                                                   ------
Net unrealized losses on securities                                                                $ (593)
                                                                                                   ======



                                                                 5





                                             ENTERPRISE BANCORP, INC.

                                      Consolidated Statements of Cash Flows

                                    Three months ended March 31, 1999 and 1998

                                                                               March 31,              March 31,
                                                                                 1999                   1998
($ in thousands)                                                             (Unaudited)             (Unaudited)       
                                                                             -----------             -----------       
                                                                                                 
Cash flows from operating activities:
     Net income                                                               $    961                   803 
     Adjustments to reconcile net income to net                                                    
        cash provided by operating activities:                                                     
               Provision for loan losses                                           135                    90
               Depreciation and amortization                                       318                   274
               Gains on sales of loans                                             (54)                  (19)
               Gains on sales of securities                                       --                     (71)
               (Increase) decrease in loans held for sale                            9                  (507)
               (Increase) decrease in accrued interest receivable                 (128)                  335
               Increase in prepaid expenses and other assets                      (127)                 (258)
               Increase in deferred income taxes                                   (12)                  (17)
               Decrease in accrued expenses and other liabilities                 (869)                 (561)
               Increase in accrued interest payable                                  6                    12
               Net change in income taxes payable/receivable                       359                   277
                                                                              --------              --------
                  Net cash provided by operating activities                        598                   358
                                                                              --------              --------
                                                                                                   
Cash flows from investing activities:                                                              
     Proceeds from maturities, calls and paydowns                                                  
        of investment securities                                                11,844                 9,842
     Purchase of investment securities                                         (12,911)               (9,080)
     Net increase in loans                                                      (6,509)              (12,250)
     Additions to premises and equipment, net                                     (760)                 (129)
                                                                              --------              --------
                  Net cash used in investing activities                         (8,336)              (11,617)
                                                                              --------              --------
                                                                                                   
Cash flows from financing activities:                                                              
     Net increase in deposits, including escrow deposits                         3,167                 9,564
     Net increase in short-term borrowings                                       3,786                 3,312
     Stock options exercised                                                        11                  --
                                                                              --------              --------
                  Net cash provided by financing activities                      6,964                12,876
                                                                              --------              --------
                                                                                                   
Net (decrease) increase in cash and cash equivalents                              (774)                1,617
                                                                                                   
Cash and cash equivalents at beginning of period                                25,923                23,554
                                                                              --------              --------
                                                                                                   
Cash and cash equivalents at end of period                                    $ 25,149                25,171
                                                                              ========              ========
                                                                                                   
                                                                                                   
Supplemental financial data:                                                                       
     Cash paid for:                                                                                
        Interest on deposits and short-term borrowings                        $  2,544                 2,416
        Income taxes                                                                51                   184
                                                                                                   
     Transfers from loans to real estate acquired by foreclosure                  --                      76
                                                        

                                
                                                        6


                            ENTERPRISE BANCORP, INC.
                          Notes to Financial Statements

(1)      Organization of Holding Company

Enterprise Bancorp, Inc. (the "company") is a Massachusetts  corporation,  which
was  organized on February 29, 1996,  at the  direction of  Enterprise  Bank and
Trust Company,  a Massachusetts  trust company (the "bank"),  for the purpose of
becoming the holding company for the bank. The company had no material assets or
operations prior to completion of the holding company reorganization on July 26,
1996.

(2)      Basis of Presentation

The accompanying  unaudited  financial  statements should be read in conjunction
with the company's  December 31, 1998,  audited  financial  statements and notes
thereto.  Interim  results  are not  necessarily  indicative  of  results  to be
expected for the entire year.

In preparing the financial statements,  management is required to make estimates
and assumptions that affect the reported amounts of assets and liabilities as of
the date of the balance  sheet and revenues and expenses for the period.  Actual
results  could  differ  from  those  estimates.   Material  estimates  that  are
particularly  susceptible to change relate to the determination of the allowance
for loan losses and valuation of other real estate owned.

In the opinion of management,  the accompanying financial statements reflect all
necessary  adjustments  consisting  of  normal  recurring  accruals  for a  fair
presentation.

(3)      Earnings Per Share

Basic  earnings per share are  calculated  by dividing net income by the year to
date  weighted  average  number of common shares that were  outstanding  for the
period. Diluted earnings per share reflect the effect on weighted average shares
outstanding  of the number of additional  shares  outstanding  if dilutive stock
options were converted  into common stock using the treasury  stock method.  The
increase in average shares outstanding, using the treasury stock method, for the
diluted earnings per share calculation were 162,289 and 127,774 for the quarters
ended March 31, 1999 and March 31, 1998, respectively.

                                       7



ITEM 2 - Management's  Discussion  and Analysis of Financial  Condition and
         Results of Operations

Capital Resources

The company's  actual capital amounts and capital  adequacy ratios are presented
in the table  below.  The  bank's  capital  amounts  and  ratios  do not  differ
materially from the amounts and ratios presented.


                                                                  Minimum Capital               Minimum Capital
                                                                    for Capital                     to be
                                             Actual              Adequacy Purposes             Well Capitalized
                                 -------------------------   ------------------------    ---------------------------   
($ in thousands)                     Amount        Ratio        Amount         Ratio        Amount          Ratio   
                                 --------------  ---------   -------------  ---------    ------------   ------------
                                                                                       
As of March 31, 1999:

Total Capital
   (to risk weighted assets)     $   30,052         12.56%   $   19,137         8.00%    $   23,921        10.00%
                                                                                                         
Tier 1 Capital                                                                                           
   (to risk weighted assets)         27,030         11.30%        9,568         4.00%        14,353         6.00%
                                                                                                         
Tier 1 Capital*                                                                                          
   (to average assets)               27,030          7.58%       14,265         4.00%        17,831         5.00%
               
<FN>                                                                            
     *    For the bank to qualify as "well capitalized",  it must maintain a leverage capital ratio (Tier 1 capital
          to average assets) of at least 5%. This requirement does not apply to the company and is reflected merely
          for informational purposes with respect to the bank.
</FN>


On April 20, 1999,  the board of directors  declared a dividend in the amount of
$0.21 per share to be paid on or about July 1, 1999 to shareholders of record as
of the close of business on June 11,  1999.  The board of  directors  intends to
consider the payment of future dividends on an annual basis.

Balance Sheet

Total Assets

Total assets  increased  $6.6 million,  or 1.8 %, since  December 31, 1998.  The
increase  is  primarily  attributable  to an  increase  in  gross  loans of $6.6
million.  The  increase in assets was funded  primarily by increases in deposits
and short-term borrowings of $3.0 million and $3.8 million, respectively.

Investments

At March 31, 1999 all of the bank's  investment  securities  were  classified as
available-for-sale  and carried at fair value.  The net unrealized gain at March
31,  1999,  net of tax  effects,  is shown as  accumulated  other  comprehensive
income, a separate component of stockholders' equity, in the amount of $403,000.
The net unrealized  gain/loss in the investment portfolio fluctuates as interest
rates rise and fall due to the fixed rate nature of the portfolio.

Loans

Total loans, before the allowance for loan losses, were $221.8 million, or 60.4%
of total  assets,  at March 31, 1999,  compared to $215.2  million,  or 59.7% of
total  assets,  at December 31, 1998.  The increase in loans of $6.6 million was
primarily  attributed to loan  originations  in the  commercial  real estate and
commercial loan portfolios. The bank continues to pursue active customer calling
efforts as well as  increased  marketing  and  advertising  to identify  quality
lending opportunities.

                                       8


Deposits and Borrowings

Total deposits, including escrow deposits of borrowers,  increased $3.2 million,
or 1.0%,  during the first three months of 1999, from $318.3 million at December
31, 1998,  to $321.5  million at March 31, 1999.  Due to the cyclical  nature of
some of the bank's deposits,  first quarter deposit growth has historically been
lower than the average  quarterly growth in deposits achieved over the remainder
of the year.

Total  borrowings,  consisting of securities sold under agreements to repurchase
and FHLB (Federal Home Loan Bank) borrowings,  increased $3.8 million, or 31.3%,
from $12.1 million at December 31, 1998 to $15.9 million at March 31, 1999.  The
increase was  attributable to an increase in securities sold under agreements to
repurchase of $3.8  million.  Management  also actively uses FHLB  borrowings in
managing  the  bank's  asset/liability  position.  The bank had FHLB  borrowings
outstanding  of $0.5  million at March 31,  1999,  and had the ability to borrow
approximately  an  additional  $95.9  million.   Management  periodically  takes
advantage  of  opportunities  t fund  asset  growth  with  borrowings,  but on a
long-term basis the bank intends to replace any FHLB borrowings with deposits.


Loan Loss Experience/Non-performing Assets

The following table summarizes the activity in the allowance for loan losses for
the periods indicated:

                                                  Three months ended March 31,
                                                  ---------------------------- 
($ in thousands)                                     1999             1998     
                                                  -----------      -----------

Balance at beginning of year                       $ 5,234            4,290 
Loans charged-off                                                  
     Commercial                                          4               65
     Commercial real estate                           --               --
     Construction                                     --               --
     Residential real estate                          --               --
     Home equity                                      --               --
     Other                                               9             --
                                                   -------          -------
                                                        13               65
                                                                   
Recoveries on loans charged off                                    
     Commercial                                         30                1
     Commercial real estate                              2             --
     Construction                                     --               --
     Residential real estate                          --                  6
     Home equity                                         2                2
     Other                                              26               32
                                                   -------          -------
                                                        60               41
                                                                   
Net loans (recovered)/charged off                      (47)              24
Provision charged to income                            135               90
                                                   -------          -------
Balance at March 31                                $ 5,416            4,356
                                                   =======          =======
                                                                   
Annualized net (recoveries)/charge-offs: Average                   
     loans outstanding                               (0.09%)           0.05%
                                                   =======          =======
Allowance for loan losses: Gross loans                2.44%            2.25%
                                                   =======          =======
Allowance for loan losses: Non-performing loans     664.54%          429.16%
                                                   =======          =======
                                                              
                                       9


The following table sets forth non-performing assets at the dates indicated:


($ in thousands)                                                 March 31,       December 31,       March 31,
                                                                   1999             1998              1998 
                                                                 ---------       ------------      ----------
                                                                                          
Loans on non-accrual:
  Commercial                                                      $  459              754              489  
  Residential real estate                                            112              113               76
  Commercial real estate                                              18               63               85
  Construction                                                      --                174             --
  Consumer, including home equity                                    138              159              300
                                                                  ------           ------           ------
     Total loans on non-accrual                                      727            1,263              950
                                                                                                   
Loans past due >90 days, still accruing                               88               97               65
                                                                  ------           ------           ------
                                                                                                   
Total non-performing loans                                           815            1,360            1,015
                                                                                                   
Other real estate owned                                              304              304              469
                                                                  ------           ------           ------
     Total non-performing loans and real estate owned             $1,119            1,664            1,484
                                                                  ======           ======           ======
                                                                                                   
Non-performing loans: Gross loans                                   0.37%            0.63%            0.53%
                                                                  ======           ======           ======
Non-performing loans and real estate owned: Total assets            0.30%            0.46%            0.44%
                                                                  ======           ======           ======
Delinquent loans 30-89 days past due: Gross loans                   0.72%            0.68%            0.74%
                                                                  ======           ======           ======

                                                                            

Total  non-performing  loans decreased $0.2 million from March 31, 1998 to March
31, 1999. The ratio of non-performing  loans to gross loans decreased from 0.53%
to 0.37% from March 31, 1998 to March 31, 1999.

Total  non-performing  loans  decreased  $0.5 million from  December 31, 1998 to
March 31,  1999.  The primary  cause for the declines was the removal of several
commercial  and  construction  loans  from  non-accrual  status.  The  ratio  of
non-performing loans to gross loans decreased from 0.63% as of December 31, 1998
to 0.37% as of March 31, 1999. The level of  non-performing  assets is largely a
function of economic conditions and the overall banking environment,  as well as
the  strength of the bank's loan  underwriting.  Non-performing  loans remain at
historically  low  levels  for the  periods  shown.  Adverse  changes  in local,
regional or national  economic  conditions could negatively  impact the level of
non-performing assets in the future, despite prudent underwriting.

Year 2000 Compliance

The statements in the following section include "Year 2000 Readiness Disclosure"
within the meaning of the Year 2000  Information  and Readiness  Disclosure Act.
This section contains certain  forward-looking  statements within the meaning of
Section 27A of the Securities Act of 1993, as amended.  The company's  readiness
for the Year 2000, and the eventual  effects of the Year 2000 on the company may
be materially different than projected.

The company is currently in the process of determining,  testing and remediating
the  impact of the  so-called  "millenium"  or "Y2K"  problem  (i.e.,  that many
existing computer chips and programs use only two digits to identify the year in
a date field and if such programs are not corrected  many computer  applications
or computer chip dependent  operations could fail or create erroneous results by
or beginning in the year 2000). While most view the project as a data processing
or computer  concern,  every  department and function of the company is affected
and  is  included  in  the  company's  analysis  and  compliance  process.   The
remediation  efforts  discussed  below  relate  to both  information  technology
systems (i.e.  computer systems,  phone systems,  telecommunications,  etc.) and
non-information  technology  systems  (i.e.  alarm  systems,  security  systems,
elevators, electrical systems, etc.).

                                       10


The company primarily  utilizes internal resources to manage the Y2K remediation
process and test, update,  and/or replace all software  information  systems for
Y2K  modifications.  The  company  has formed a "Year 2000  Steering  Committee"
consisting of various members of senior management and all department  managers.
The Year 2000  Steering  Committee's  purpose is to  evaluate  risks,  formulate
timetables and allocate  resources to ensure timely and effective  completion of
Y2K  testing  and  remediation.  The company  also has a  technology  committee,
consisting of certain  members of the Board of Directors and  management,  which
oversees the Year 2000 Steering Committee and is responsible for ensuring proper
reporting of results to the full Board of Directors.  One full time  information
system specialist is solely devoted to Y2K issues. Many other employees are also
actively involved including each department manager,  members of their staff and
the entire information  systems  department.  The company also utilizes external
resources  (information systems consultants,  auditors,  speakers,  accountants,
etc.) as deemed necessary by the various committees and management.

Management has completed its assessment of Y2K issues,  developed a plan,  begun
testing its various software  information  systems and arranged for the required
resources,  based on anticipated  needs, to complete the necessary  remediation.
Management has completed the changes to and testing of internal mission critical
information  systems for the Y2K project and expects to complete the changes and
testing required for mission critical systems  associated with service providers
by June 30, 1999,  which is the timeframe  established by the Federal  Financial
Institutions  Examination Council ("FFIEC").  Mission critical systems are those
critical  to daily  operations  and  failure of which  would  result in definite
disruption  to  business.   Testing  of  the  company's   non-mission   critical
applications  will  continue  through  1999 and will be  completed  prior to any
anticipated  impact on its operating  systems.  Contingency plans are also being
developed for each  function so that the company is  adequately  prepared in the
event of a system failure,  despite remediation  efforts. A sub-committee of the
Y2K Steering Committee has been formed to facilitate  preparation of contingency
plans.  These  contingency  plans will be completed  prior to June 30, 1999,  in
accordance with FFIEC guidelines.  Additionally, the bank has formed a coalition
with  surrounding  financial  institutions  to  periodically  meet  and  discuss
contingency plans and pool resources to deal with potential  disruptions.  (i.e.
failure of security systems, failure of electrical grids, cash needs, etc.).

Included in other non-interest  expenses are charges incurred in connection with
the preparation,  testing,  modification or replacement of software and hardware
in connection with the process of rendering the company's  computer  systems Y2K
compliant. Excluding internal salary and benefit costs, approximately $10,000 in
costs associated with Y2K remediation efforts were expended through December 31,
1998 and $10,000 in the first quarter of 1999. Management expects that the costs
incurred  to  replace  or  upgrade  existing   hardware  and  software  will  be
capitalized and amortized in accordance with the company's  existing  accounting
policies, while miscellaneous consulting,  salary,  maintenance and modification
costs will be expensed as incurred. Anticipated future costs, excluding internal
salary and benefit  costs,  associated  with Y2K  compliance  are  estimated  at
$150,000,  which includes  upgrades of security  systems,  modifications  to the
automated   teller    machines,    consulting   costs   and   changes   to   the
telecommunications  network.  The estimated  expenses in 1999 include consulting
fees for Year 2000 project  management of $75,000.  Due to short term  personnel
constraints  it was necessary to engage  consultants  to assist in the Year 2000
management process.  Other than the one dedicated  information system specialist
the  company  does not  separately  track the  portion of its salary and benefit
costs  allocable  to the  Y2K  project.  It is  not  anticipated  that  material
incremental costs will be incurred in any single period.

The cost of the project and the date on which the company  plans to complete the
Y2K modifications  are based on management's best estimates,  which were derived
utilizing  numerous   assumptions  of  future  events  including  the  continued
availability of certain  resources,  third party availability and other factors.
However,  there can be no guarantee  that these  estimates  will be achieved and
actual results could differ  materially from those plans.  Specific factors that
might  cause such  material  differences  include,  but are not  limited to, the
availability  and cost of  personnel  trained in this area,  employee  turnover,
non-compliance  of the  company's  vendors  or  service  providers  and  similar
uncertainties.  The  company  is working  closely  with all of its  vendors  and
service  providers to determine the extent to which the company is vulnerable to
those third parties' failure to remediate their own Y2K issues.

                                       11



Management  recognizes  the potential risk of Y2K on the bank's  customers.  The
bank has approached  the credit risk  component of Y2K through  education of all
lending officers, education of customers, analysis of the bank's loan portfolio,
and consideration of Y2K in the underwriting of loans. All lending officers were
required to undergo  internal  training to learn the potential risks of Y2K. The
bank has sponsored and intends to continue sponsoring numerous seminars for bank
customers,  in addition  to  distribution  of  literature  regarding  Y2K to all
customers.  In 1998,  an analysis of the bank's  commercial  loan  portfolio was
performed  to  determine  potential  exposure  to Y2K  risks.  Increases  in the
allowance for loan losses, solely as a result of Y2K, were not deemed necessary.
Any new commercial  loans require an assessment of the customer's Y2K compliance
as part of preliminary  underwriting.  The need for additional provisions to the
bank's  allowance  for loan losses  resulting  from  borrowers'  Y2K  compliance
problems  will  be  considered,  on an  ongoing  basis,  based  on  management's
assessment of the potential exposure of its customer base to such problems.

The internal and external risks associated with Y2K are numerous. The company is
addressing the Y2K issue in accordance with regulatory guidelines promulgated by
the FFIEC.  However,  there can be no guarantee that the systems of the company,
bank customers or other associated  companies (i.e. electric company,  telephone
company,  printing  companies,  office  supply  companies,  etc.) will be timely
remediated. There can be no guarantee that the systems of third party vendors on
which the company's systems rely will be timely  remediated.  The failure of the
company or a critical  third party vendor to timely  remediate  Y2K issues might
cause,  among  other  things,  systems  malfunctions,  incorrect  or  incomplete
transaction  processing  or the  inability  to  reconcile  accounting  books and
records.

The company's operations and/or financial condition could possibly be negatively
impacted to the extent the company,  customers or entities  doing  business with
the company are unsuccessful in timely and properly  addressing their respective
Y2K compliance responsibilities.


                                       12



                              Results of Operations
     Three Months Ended March 31, 1999 vs. Three Months Ended March 31, 1998

The company reported net income of $961,000 for the three months ended March 31,
1999,  versus $803,000 for the three months ended March 31, 1998, or an increase
of 19.7%. The company had basic earnings per common share of $0.30 and $0.25 for
the three months ended March 31, 1999 and March 31, 1998, respectively.  Diluted
earnings  per share were $0.29 and $0.24 for the three  months  ending March 31,
1999 and March 31,1998, respectively.

The following table highlights  changes,  which affected the company's  earnings
for the periods indicated:


                                                                         Three months ended March 31,      
                                                                         ----------------------------      
($ in thousands)                                                        1999                     1998     
                                                                     ----------                ---------

                                                                                              
Average assets                                                       $ 355,779                   322,992
Average deposits and short-term borrowings                             325,519                   297,182
Average investment securities (1)                                      115,022                   112,601
Average loans, net of deferred loan fees                               217,157                   185,902
Net interest income                                                      3,980                     3,640
Provision for loan losses                                                  135                        90
Tax expense                                                                398                       445
Average loans : Average deposits and borrowings                          66.71%                    62.55%
Non interest expense : Average assets (2)                                 3.54%                     3.68%
Non interest income, exclusive of securities
  gains : Average assets (2)                                               .71%                      .70%
Average tax equivalent rate earned on interest earning assets             8.12%                     8.32%
Average rate paid on interest bearing deposits and
   short-term borrowings                                                  3.85%                     4.00%
Net yield on average earning assets                                       5.04%                     5.04%
<FN>
(1) Average investment securities are shown at average amortized cost 
(2) Ratios have been annualized based on number of days for the period
</FN>


Net Interest Income

The  company's  net interest  income was  $3,980,000  for the three months ended
March 31, 1999,  an increase of $340,000 or 9.3% from  $3,640,000  for the three
months ended March 31, 1998.  Interest income  increased  $462,000,  primarily a
result of an increase of average loan balances of $31.3  million,  or 16.8% from
the  quarter  ended March 31, 1998 to the  quarter  ended  March 31,  1999.  The
increase  in  interest  income was  partially  offset by an increase in interest
expense of  $122,000,  primarily  due to an  increase  in average  deposits  and
short-term borrowings of $22.5 million over the same period.

The average  tax-equivalent  yield on earning  assets in the three  months ended
March 31, 1999,  was 8.12%,  down 20 basis points from 8.32% in the three months
ended March 31,  1998.  The average rate paid on interest  bearing  deposits and
short-term  borrowings  in the three months ended March 31, 1999,  was 3.85%,  a
decrease of 15 basis points from 4.00% in the three months ended March 31, 1998.
The  resulting  interest  rate spread  decreased 5 basis  points to 4.27% in the
three months  ended March 31,  1999,  from 4.32% in the three months ended March
31, 1998. The decline in the average loan yield from 9.45% to 8.92%,  from March
31, 1998 to March 31, 1999,  was primarily a result of the prime rate  declining
by 75 basis  points in the fourth  quarter of 1998.  Similarly,  the  decline in
average deposit rates paid was a result of declining market rates offered during
the same period.

The following table sets forth,  among other things, the extent to which changes
in interest rates and changes in the average balances of interest-earning assets
and  interest-bearing  liabilities  have  affected  interest  income and expense
during the three  months ended March 31, 1999,  and 1998.  For each  category of
interest-earning  assets  and  interest-bearing   liabilities,   information  is
provided on changes  attributable  to: (1) volume  (change in average  portfolio
balance  multiplied  by prior year average  rate);  (2) interest rate (change in
average  interest rate multiplied by prior year average  balance);  and (3) rate
and volume (the remaining difference).

                                       13




                                   AVERAGE BALANCES, INTEREST AND AVERAGE INTEREST RATES

                                              Three Months Ended March 31, 1999  Three Months Ended March 31, 1998   
                                              ---------------------------------  ---------------------------------   
                                                 Average             Interest    Average                Interest     
($ in thousands)                                 Balance   Interest  Rates (3)   Balance    Interest    Rates (3)    
                                                 --------  --------  ---------   -------    --------    ---------    
                                                                                        
Assets:
    Loans  (1) (2)                               $217,157   $4,774    8.92%     $185,902     $ 4,331       9.45%    
    Investment securities (3)                     115,022    1,712    6.74       112,601       1,713       6.50     
    Federal funds sold                              3,842       44    4.64         1,691          24       5.76     
                                                 --------   ------              --------     -------          
      Total interest earnings assets              336,021    6,530    8.12%      300,194       6,068       8.32%    
                                                            ------                           -------
    Other assets (4)                               19,758                         22,798
                                                 --------                       --------
      Total assets                               $355,779                       $322,992
                                                 ========                       ========
Liabilities and stockholders' equity:
    Savings, NOW and money market                $109,779      553    2.04%     $106,538         588       2.24%    
    Time deposits                                 144,369    1,845    5.18       122,760       1,671       5.52     
    Short-term borrowings                          14,380      152    4.29        16,762         169       4.09     
                                                 --------   ------              --------     -------          
      Interest bearing deposits and borrowings    268,528    2,550    3.85%      246,060       2,428       4.00%    
                                                 --------   ------              --------     -------        
    Non-interest bearing deposits                  56,991                         51,122
    Other liabilities                               3,706                          2,187
                                                 --------                       --------
      Total liabilities                           329,283                        299,369

Stockholders' equity                               26,496                         23,623
                                                 --------                       --------
      Total liabilities and
      Stockholders' equity                       $355,779                       $322,992
                                                 ========                       ========
Net interest rate spread                                            4.27%                                  4.32%

Net interest income                                         $3,980                            $3,640                
                                                            ======                            ======                
Net yield on average earning assets                                 5.04%                                  5.04%

($ in thousands)                                                           Changes due to                           
                                                        ---------------------------------------------------    
                                                                                     Interest        Rate/       
                                                        Total         Volume           Rate          Volume        
                                                        -----         ------         --------        ------        
                                                                                        
Assets:                                         
    Loans  (1) (2)                                      $ 443          $ 728          $ (243)        $ (42)         
    Investment securities (3)                              (1)            39              67          (107)         
    Federal funds sold                                     20             31              (5)           (6) 
                                                        -----          -----          ------         -----          
      Total interest earnings assets                      462            798            (181)         (155) 
                                                        -----          -----          ------         ----- 
    Other assets (4)                                                                                                

      Total assets                                                                                                  
                                                                                                                    
Liabilities and stockholders' equity:                                                                               
    Savings, NOW and money market                         (35)            18             (53)           --          
    Time deposits                                         174            294            (103)          (17)         
    Short-term borrowings                                 (17)           (24)              8            (1) 
                                                        -----          -----          ------         -----                         
      Interest bearing deposits and borrowings            122            288            (148)          (18)  
                                                        -----          -----          ------         -----          
    Non-interest bearing deposits                                                                      
    Other liabilities                                                                                               
                                                                                                                    
      Total liabilities                                                                                             
                                                                                                                    
Stockholders' equity                                                                                                
                                                                                                                    
      Total liabilities and                                                                                         
      Stockholders' equity                                                                                          
                                                                                                                    
Net interest rate spread                                                                                            
                                                                                                                    
Net interest income                                     $ 340          $ 510          $  (33)        $(137)         
                                                        =====          =====          ======         =====                          
Net yield on average earning assets                                                                                 
<FN>                            
(1)  Average loans include non-accrual loans.

(2)  Average loans are net of average deferred loan fees.

(3)  Average balances are presented at average amortized cost and average interest rates are presented on a tax-equivalent basis.

(4)  Other assets include cash and due from banks, accrued interest  receivable,  allowance for loan losses, real estate acquired by
     foreclosure, deferred income taxes and other miscellaneous assets.
</FN>


The bank manages its earning assets by fully using available  capital  resources
within what  management  believes are prudent  credit and  leverage  parameters.
Loans, investment securities, and federal funds sold comprise the bank's earning
assets.

                                                                 14

The  provision  for loan losses  amounted to $135,000  and $90,000 for the three
months ended March 31, 1999 and March 31, 1998, respectively. With the growth in
the  company's  loan  portfolio  during  1997 and early  1998,  the ratio of the
allowance for loan losses to gross loans had declined.  In the second quarter of
1998,  management  determined  that further erosion of the ratio was not prudent
and  increased  the  provision  to keep  pace  with  further  growth in the loan
portfolio.  Loans,  before the allowance for loan losses,  have  increased  from
$193.3 million,  at March 31, 1998, to $221.8 million,  at March 31, 1999, or an
increase of 14.8%.  Although  there has not been an increase in problem  assets,
management recognizes the increased risk and the need for additional reserves as
the loan  balances  increase.  The  provision  reflects  real estate  values and
economic  conditions in New England and in Greater  Lowell,  in particular,  the
level of non-accrual  loans,  levels of charge-offs  and  recoveries,  levels of
outstanding  loans, known and inherent risks in the nature of the loan portfolio
and management's  assessment of current risk. The provision for loan losses is a
significant factor in the bank's operating results.

Non-Interest Income

Non-interest  income,  exclusive  of  security  gains,  increased  by $63,000 to
$622,000 for the three months ended March 31, 1999, compared to $559,000 for the
three months  ended March 31, 1998.  This  increase was  primarily  caused by an
increase in trust fees of $48,000.

Trust fees increased by $48,000,  or 20.3%, for the three months ended March 31,
1999  compared to the same  period in 1998 due to an  increase in trust  assets.
Trust assets  increased  from $180.3 million at March 31, 1998 to $200.7 million
at March 31, 1999.

Deposit fees decreased by $14,000, or 6.4%, for the three months ended March 31,
1999,  compared to the three  months ended March 31,  1998,  due  primarily to a
decrease in overdrafts.

Other income for the three months ended March 31, 1999, was $78,000,  a decrease
of 7.1%,  from $84,000 for the three months ended March 31, 1998,  due primarily
to a decrease in letter of credit fees.

Non-Interest Expenses

Salaries  and benefits  expense  totaled  $1,873,000  for the three months ended
March 31, 1999,  compared with  $1,678,000  for the three months ended March 31,
1998,  an increase of $195,000 or 11.6%.  This increase was primarily the result
of new hires to  support  the  overall  growth of the bank,  and  annual  salary
increases.

Occupancy  expense was  $577,000  for the three  months  ended  March 31,  1999,
compared with $555,000 for the three months ended March 31, 1998, an increase of
$22,000 or 4.0%.  The increase was primarily due to the addition and  renovation
of new facilities for the bank's  accounting and loan servicing  departments and
the customer service center.

Advertising and public relations  expenses  increased by $18,000,  or 17.0%, for
the three months ended March 31, 1999  compared to the same period in 1998.  The
increase was primarily attributed to expenses associated with the advertisements
for new employees and timing of other advertising programs.

Audit,  legal and other  professional  expenses decreased by $6,000, or 4.8% for
the three  months  ended  March 31,  1999  compared  to the prior  year  period,
primarily due to professional  services  engaged by the bank in 1998, but not in
the three months ended March 31, 1999.

Trust, professional and custodial expenses decreased by $7,000, or 9.5%, for the
three  months  ended March 31, 1999 as compared to the same period in 1998.  The
decrease was primarily due to the timing of certain professional management fees
in 1998.

Office and data processing  supplies expense decreased by $32,000, or 34.4%, for
the three months  ended March 31, 1999  compared to the same period in the prior
year. The decrease was primarily due to various cost saving initiatives.

                                       15


ITEM 3 - Quantitative and Qualitative Disclosures About Market Risk

The company's primary market risk is interest rate risk,  specifically,  changes
in the interest rate environment. The bank's investment committee is responsible
for establishing  policy guidelines on acceptable exposure to interest rate risk
and liquidity.  The investment  committee is comprised of certain members of the
Board of  Directors  and  certain  members  of senior  management.  The  primary
objectives of the company's  asset/liability policy is to monitor,  evaluate and
control the bank's  interest rate risk,  as a whole,  within  certain  tolerance
levels while ensuring adequate  liquidity and adequate  capital.  The investment
committee  establishes  and  monitors  guidelines  for the net  interest  margin
sensitivity,  equity  to  capital  ratios,  liquidity,  Federal  Home  Loan Bank
borrowing capacity and loan to deposit ratio. The asset/liability strategies are
reviewed regularly by management and presented and discussed with the investment
committee on at least a quarterly  basis.  The  asset/liability  strategies  are
revised based on changes in interest rate levels,  general economic  conditions,
competition in the marketplace,  the current  position of the bank,  anticipated
growth of the bank and other factors.

One of the  principal  factors in  maintaining  planned  levels of net  interest
income is the  ability to design  effective  strategies  to manage the impact of
changes in  interest  rates on future net  interest  income.  The  balancing  of
changes in interest income from interest  earning assets and interest expense of
interest  bearing  liabilities  is  accomplished   through  the  asset/liability
management  program.  The bank's simulation model analyzes various interest rate
scenarios.  Variations in the interest rate environment affect numerous factors,
including prepayment speeds,  reinvestment rates, maturities of investments (due
to call provisions), and interest rates on various asset and liability accounts.
The  investment  committee   periodically  reviews  guidelines  or  restrictions
contained in the asset/liability policy and adjusts them accordingly. The bank's
current  asset/liability  policy is designed to limit the impact on net interest
income to 10% in the 24 month period  following the date of the  analysis,  in a
rising and falling rate shock analysis of 100 and 200 basis points.

Management  believes  there have been no material  changes in the interest  rate
risk reported in the  company's  Annual Report on Form 10-KSB for the year ended
December 31, 1998.

                                       16



                           PART II - OTHER INFORMATION


Item 1            Legal Proceedings
                  Not Applicable

Item 2            Changes in Securities and Use of Proceeds
                  Not Applicable

Item 3            Defaults upon Senior Securities
                  Not Applicable

Item 4            Submission of Matters to a Vote of Security Holders
                  Not Applicable

Item 5            Other Information
                  None

Item 6            Exhibits and Reports on Form 8-K
                  The following exhibits are included with this report:
                  3.1     Restated Articles of Organization of the Company, as 
                          amended through May 10,1999.
                  10.17   Split Dollar Agreement for Richard W. Main
                  10.18   Split Dollar Agreement for Robert R. Gilman
                  27.1    Financial Data Schedule (included with electronic 
                          copy only)

                                       17





                                   SIGNATURES


Pursuant to the  requirements  of the  Securities  and Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.


                                 ENTERPRISE BANCORP, INC.

DATE:  May  14, 1999             /s/ John P. Clancy, Jr.
                                 John P. Clancy, Jr.
                                 Senior Vice President, Chief Financial Officer,
                                 Chief Investment Officer and Treasurer


                                       18