UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form 13F-HR
Form 13F COVER PAGE
Report for the Calendar Year of Quarter Ended: March 31, 2013
Check here if Amendment [ ]; Amendment Number:
This Amendment (Check only one.): [ ] is a restatement.
[ ] adds new holdings entries.
Institutional Investment Manager Filing this Report:
Name: Perceptive Advisors LLC
Address: 499 Park Ave, 25th Floor
New York, NY 10022
Form 13F File Number: 28-10438
The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form.
Person Signing this Report on Behalf of Reporting Manager:
Name: Joseph Edelman
Title: Managing Member
Phone: (646) 205-5342
Signature, Place, and Date of Signing:
/s/ Joseph Edelman New York, NY May 15, 2013
[Signature] [City, State] [Date]
Report Type (Check only one.):
[ X ] 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager
are reported in this report.)
[ ] 13F NOTICE. (Check here if no holdings reported are in this report, and all
holdings are reported by other reporting manager(s).)
[ ] 13F COMBINATION REPORT. (Check here if a portion of the holdings for this
reporting manager are reported in this report and a portion are reported by
other reporting manager(s).)
Form 13F SUMMARY PAGE
Report Summary:
Number of Other Included Managers: 0
Form 13F Information Table Entry Total: 78
Form 13F Information Table Value Total: $832,171
(thousands)
List of Other Included Managers:
{None}
Title
of Value Shs or Sh/ Put/ Investment Other Voting Authority
Name of Issuer Class CUSIP (x1000) Prn Amt Prn Call Discretion Managers Sole Shared None
ALKERMES PLC SHS G01767105 1,185 50,000 SH Sole 50,000
COVIDIEN PLC SHS G2554F113 10,617 156,500 SH Sole 156,500
ACELRX PHARMACEUTICALS INC COM 00444T100 25,843 5,008,400 SH Sole 5,008,400
ACHILLION PHARMACEUTICALS IN COM 00448Q201 875 100,000 SH Sole 100,000
AEGERION PHARMACEUTICALS INC COM 00767E102 8,068 200,000 C Sole 200,000
AEGERION PHARMACEUTICALS INC COM 00767E102 136,084 3,373,426 SH Sole 3,373,426
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 3,826 157,000 SH Sole 157,000
ANTHERA PHARMACEUTICALS INC COM 03674U102 2,278 3,451,655 SH Sole 3,451,655
ASTEX PHARMACEUTICALS INC COM 04624B103 9,345 2,092,855 SH Sole 2,092,855
ATHERSYS INC COM 04744L106 7,487 4,456,797 SH Sole 4,456,797
BIOGEN IDEC INC COM 09062X103 7,223 37,500 SH Sole 37,500
BIOMED REALTY TRUST INC COM 09063H107 1,361 63,000 SH Sole 63,000
CAPITAL SR LIVING CORP COM 140475104 22,294 843,500 SH Sole 843,500
CELGENE CORP COM 151020104 5,796 50,000 P Sole 50,000
CELGENE CORP COM 151020104 12,171 105,000 SH Sole 105,000
CELLDEX THERAPEUTICS INC NEW COM 15117B103 579 50,000 SH Sole 50,000
CELSION CORPORATION COM NEW 15117N305 1,313 1,250,000 P Sole 1,250,000
CELSION CORPORATION COM NEW 15117N305 479 456,500 SH Sole 456,500
CEMPRA INC COM 15130J109 3,038 450,000 SH Sole 450,000
CHELSEA THERAPEUTICS INTL LT COM 163428105 11,485 5,630,000 SH Sole 5,630,000
CHAMPIONS ONCOLOGY INC RSTD COM 15870p109 1,084 1,808,244 SH Sole 1,808,244
COMBIMATRIX CORPORATION *W EXP 05/01/201 20009T121 2 5,000 SH Sole 5,000
CONCEPTUS INC COM 206016107 8,736 361,733 SH Sole 361,733
CUTERA INC COM 232109108 4,906 377,350 SH Sole 377,350
DYAX CORP COM 2.67E+107 3,276 751,457 SH Sole 751,457
EMERITUS CORP COM 291005106 278 10,000 SH Sole 10,000
EXACT SCIENCES CORP COM 30063P105 9,002 918,600 P Sole 918,600
EXACT SCIENCES CORP COM 30063P105 1,225 125,000 C Sole 125,000
EXACT SCIENCES CORP COM 30063P105 10,935 1,115,808 SH Sole 1,115,808
GILEAD SCIENCES INC COM 375558103 13,517 276,200 SH Sole 276,200
HCA HOLDINGS INC COM 40412C101 15,439 380,000 SH Sole 380,000
HEARTWARE INTL INC COM 422368100 884 10,000 SH Sole 10,000
IMMUNOMEDICS INC COM 452907108 1,781 739,144 SH Sole 739,144
INFINITY PHARMACEUTICALS INC COM 45665G303 24,235 500,000 P Sole 500,000
INFINITY PHARMACEUTICALS INC COM 45665G303 133,256 2,749,255 SH Sole 2,749,255
INTERMUNE INC COM 45884X103 2,715 300,000 SH Sole 300,000
ISIS PHARMACEUTICALS INC COM 464330109 3,388 200,000 C Sole 200,000
ISIS PHARMACEUTICALS INC COM 464330109 1,694 100,000 P Sole 100,000
LEXICON PHARMACEUTICALS INC COM 528872104 6,975 3,199,500 SH Sole 3,199,500
LIPOSCIENCE INC COM 53630M108 685 65,129 SH Sole 65,129
MGC DIAGNOSTICS CORP COM 552768103 973 139,264 SH Sole 139,264
MEDGENICS INC COM NEW 58436Q203 728 150,000 SH Sole 150,000
MEDIVATION INC COM 58501N101 818 17,500 SH Sole 17,500
MYRIAD GENETICS INC COM 62855J104 254 10,000 P Sole 10,000
NPS PHARMACEUTICALS INC COM 62936P103 3,086 302,400 SH Sole 302,400
NAVIDEA BIOPHARMACEUTICALS I COM 63937X103 54 20,000 P Sole 20,000
NEOSTEM INC COM NEW 640650305 2,255 3,315,938 SH Sole 3,315,938
NEPTUNE TECHNOLOGIES BIORESO COM 64077P108 8,878 3,522,920 SH Sole 3,522,920
NEUROCRINE BIOSCIENCES INC COM 64125C109 53,492 4,402,637 SH Sole 4,402,637
NEWLINK GENETICS CORP COM 651511107 3,681 300,000 SH Sole 300,000
NOVARTIS A G SPONSORED ADR 66987V109 7,430 104,300 SH Sole 104,300
PROLOR BIOTECH INC COM 74344F106 7,040 1,391,243 SH Sole 1,391,243
QUESTCOR PHARMACEUTICALS INC COM 74835Y101 3,254 100,000 C Sole 100,000
QUESTCOR PHARMACEUTICALS INC COM 74835Y101 14,512 446,000 SH Sole 446,000
RTI BIOLOGICS INC COM 74975N105 107 27,312 SH Sole 27,312
REGENERON PHARMACEUTICALS COM 75886F107 11,466 65,000 SH Sole 65,000
REPROS THERAPEUTICS INC COM NEW 76028H209 3,220 200,000 P Sole 200,000
REPROS THERAPEUTICS INC COM NEW 76028H209 10,506 652,650 SH Sole 652,650
RIGEL PHARMACEUTICALS INC COM NEW 766559603 680 100,000 P Sole 100,000
SAREPTA THERAPEUTICS INC COM 803607100 1,848 50,000 P Sole 50,000
SAREPTA THERAPEUTICS INC COM 803607100 9,237 250,000 C Sole 250,000
SAREPTA THERAPEUTICS INC COM 803607100 99,269 2,686,600 SH Sole 2,686,600
SHIRE PLC SPONSORED ADR 82481R106 19,259 210,800 SH Sole 210,800
STEMCELLS INC COM NEW 85857R204 401 231,600 SH Sole 231,600
SUNESIS PHARMACEUTICALS INC COM NEW 867328601 317 58,010 SH Sole 58,010
SUPERNUS PHARMACEUTICALS INC COM 868459108 3,275 582,829 SH Sole 582,829
SYNTA PHARMACEUTICALS CORP COM 87162T206 860 100,000 P Sole 100,000
SYNTA PHARMACEUTICALS CORP COM 87162T206 8,542 993,236 SH Sole 993,236
TRANSGENOMIC INC RSTD COM 89365K206 790 2,000,000 SH Sole 2,000,000
TEKMIRA PHARMACEUTICALS CORP COM NEW 87911B209 1,517 320,000 SH Sole 320,000
TESARO INC COM 881569107 4,346 197,900 SH Sole 197,900
UROPLASTY INC COM NEW 917277204 716 287,613 SH Sole 287,613
VENTRUS BIOSCIENCES INC COM 922822101 1,674 560,000 SH Sole 560,000
VERTEX PHARMACEUTICALS INC COM 92532F100 10,994 200,000 SH Sole 200,000
VIROPHARMA INC COM 928241108 19,029 756,300 SH Sole 756,300
VIVUS INC COM 928551100 1,100 100,000 P Sole 100,000
XOMA CORP DEL COM 98419J107 1,020 292,250 SH Sole 292,250
ZIOPHARM ONCOLOGY INC COM 98973P101 183 100,000 C Sole 100,000
832,171