EMPLOYMENT AGREEMENT

           THIS AGREEMENT is made as of this 14th day of October 2004,


BETWEEN:

                        VIVENTIA BIOTECH INC., a corporation continued under
                        the laws of Ontario

                        (the "CORPORATION")

                        - and -

                        Michael Byrne of the City of Mississauga, in the
                        Province of Ontario

                        (the "EXECUTIVE")


RECITALS:

A.   The Corporation and the Executive wish to enter into this Agreement to set
     forth the rights and obligations of each of them as regards the Executive's
     employment with the Corporation.

     NOW THEREFORE in consideration of the mutual covenants and agreements
contained in this Agreement and other good and valuable consideration (the
receipt and sufficiency of which are hereby acknowledged), the Corporation and
the Executive agree as follows:


1.   DEFINITIONS


1.1. In this Agreement,

     1.1.1. "AFFILIATE" has the meaning attributed to such term in the Business
     Corporations Act (Ontario) as the same may be amended from time to time and
     any successor legislation thereto;

     1.1.2. "AGREEMENT" means this agreement and all schedules attached to this
     agreement, in each case as they may be amended or supplemented from time to
     time, and the expressions "HEREOF", "HEREIN", "HERETO", "HEREUNDER",
     "HEREBY" and similar expressions refer to this agreement and unless
     otherwise indicated, references to sections are to sections in this
     agreement;

     1.1.3. "BASIC SALARY" has the meaning attributed to such term in section
     5.1;



                                      -2-

     1.1.4. "BENEFITS" has the meaning attributed to such term in section 5.3;

     1.1.5. "BIO-PHARMACEUTICAL BUSINESS" has the meaning attributed to that
     term in section 2;

     1.1.6. "BONUS" has the meaning attributed to such term in section 5.2;

     1.1.7. "BOARD" means the board of directors of the Corporation;

     1.1.8. "BUSINESS DAY" means any day, other than Saturday, Sunday or any
     statutory holiday in the Province of Ontario;

     1.1.9. "CONFIDENTIAL INFORMATION" means all confidential or proprietary
     information, intellectual property and confidential facts relating to and
     used or proposed to be used in the business of the Corporation and its
     Affiliates and includes all information which is confidential based upon
     its nature or the circumstances surrounding its disclosure, including such
     information acquired by the Executive during any period in which the
     Executive was affiliated with the Corporation in any capacity, including as
     an employee, director or shareholder, and includes, without limiting the
     generality of the foregoing, information:

       (a)  relating to the Corporation's or an Affiliate's biotechnology or
            bio- pharmaceutical products and services, products and services
            related to biotechnology or the Bio-Pharmaceutical Business, or to
            the Corporation's or an Affiliate's research and development
            projects or plans;

       (b)  relating to the Corporation's or an Affiliate's trade secrets,
            technology, patentable and unpatentable inventions, discoveries,
            texts, cell lines, nucleic acid, protein and peptide sequences,
            synthetic procedures, processes, test procedures and results,
            records, specifications, data, formulations, know-how, samples,
            specimens, manufacturing processes, toxicology, regulatory and
            clinical information;

       (c)  relating to the Corporation's or an Affiliates business policies,
            strategies, operations, finances, plans or opportunities including
            the identity of, or particulars about, the Corporation's clients or
            suppliers or other Person with whom the Corporation has a business
            relationship; and

       (d)  marked or otherwise identified as confidential, restricted, secret
            or proprietary including, without limiting the generality of the
            foregoing, information acquired by inspection or oral disclosure;

     provided that Confidential Information does not extend to the skill,
     expertise, know-how and experience of the Executive gained in the
     performance of his employment.

     1.1.10. "DISABILITY" means the mental or physical state of the Executive
     such that the Executive has been unable as a result of illness, disease,
     mental or physical disability or similar cause to fulfil his obligations
     under this Agreement either for any consecutive six




                                      -3-

     month period or for any period of aggregating twelve (12) months (whether
     or not consecutive) in any consecutive twenty-four (24) month period;

     1.1.11. "EMPLOYMENT PERIOD" has the meaning attributed to such term in
     section 4;

     1.1.12. "ESA" means the Employment Standards Act, 2000 (Ontario) as the
     same may be amended from time to time and any successor legislation
     thereto;

     1.1.13. "JUST CAUSE" includes the willful failure of the Executive to
     properly carry out his duties after notice by the Corporation of the
     failure to do so and an opportunity for the Executive to correct the same
     within a reasonable time from the date of receipt of such notice, or theft,
     fraud, dishonesty or misconduct by the Executive involving the property,
     business or affairs of the Corporation or the carrying out of the
     Executive's duties or any other conduct or omission which is to be treated
     as just cause by the courts of Ontario from time to time;

     1.1.14."PERSON" means any individual, partnership, limited partnership,
     joint venture, syndicate, sole proprietorship, company or corporation with
     or without share capital, unincorporated association, trust, trustee,
     executor, administrator or other legal personal representative, regulatory
     body or agency, government or governmental agency, authority or entity
     however designated or constituted;

     1.1.15. "RETIREMENT" means resignation of the Executive on or after the
     Executive attains the age of sixty-five (65);

     1.1.16. "SEVERANCE AMOUNT" has the meaning attributed to such term in
     section 9;

     1.1.17. "SUBSIDIARIES" has the meaning attributed to such term by the
     Business Corporations Act (Ontario) as the same may be amended from time to
     time and any successor legislation thereto;

     1.1.18. "TERMINATION WITHOUT CAUSE" means termination for any reason other
     than for Just Cause or for Disability or by reason of resignation or
     Retirement by the Executive;

     1.1.19."YEAR OF EMPLOYMENT" means any twelve (12) month period commencing
     on January 1, 2004 or on any anniversary of such date.


2.   EMPLOYMENT OF THE EXECUTIVE

     The Corporation shall employ the Executive and the Executive shall serve
the Corporation in the position of Chief Financial Officer. The Executive shall
report to the President and CEO. In the capacity as Chief Executive Officer, the
Executive will play an important strategic role in the conduct of the business
and will be privy to, and acquire detailed knowledge of, Confidential
Information and other business sensitive information about the Corporation and
its Affiliates and will assist in the business of:




                                      -4-


     2.1.1.1. research, development, clinical trials, regulatory compliance,
     marketing, sales, manufacturing, distribution, licensing or other
     exploitation of:

     2.1.1.2. monoclonal antibody products, including without limitation human
     monoclonal antibodies;

     2.1.1.3. the use of the human immune system to identify therapeutically or
     diagnostically relevant antibodies and their cognate antigens for cancer;

     2.1.1.4. and any exploitation thereof, related research, products and
     services to any of the above and products derived from any of the above

  (the "BIO-PHARMACEUTICAL BUSINESS").

Without limiting the generality of the foregoing, the Executive's duties shall
include:

2.2. management of activities that relate to the Bio-Pharmaceutical Business,
     including finance, payroll, human resources, investor relations, financial
     reporting, corporate communications and Corporate Secretary.


3.   PERFORMANCE OF DUTIES

     The Executive represents and warrants that neither his execution of the
Employment Agreement nor his performance of the duties and obligations set out
in the Employment Agreement does or will violate or breach any obligation he may
have to any third party or imposed by statute, contract or order of any judicial
or quasi-judicial authority. During the Employment Period, the Executive shall
faithfully, honestly and diligently serve the Corporation. The Executive shall
(except in the case of illness or accident) devote all of his working time and
attention to his employment and shall use his best efforts to promote the
interests of the Corporation.


4.   EMPLOYMENT PERIOD

     The term of employment of the Executive under this Agreement will commence
on January 1, 2004 and will continue until terminated in accordance with section
8 of this Agreement (the "EMPLOYMENT PERIOD").


5.   REMUNERATION

5.1. Basic Remuneration. The Corporation shall pay the Executive a gross annual
     salary of $175,000 (the "BASIC SALARY") payable in periodic equal
     instalments in accordance with the practices of the Corporation applicable
     to its other senior executives.

5.2. Bonus Remuneration. The Board may award the Executive, an annual bonus of
     cash, stock options, other share based compensation or any combination
     thereof. Such bonus shall be awarded in the sole discretion of the Board
     (the "BONUS") at the recommendation





                                       -5-


     of the Chief Executive Officer. Each year, at the time that the Board
     approves the Corporation's annual business plan and annual budget, the
     Executive and the Board (or a committee thereof) shall mutually agree on
     the objectives upon which any Bonus shall be based. Such objectives may
     include subjective and objective criteria.

5.3. Benefits. The Corporation shall provide to the Executive, in addition to
     Basic Salary and Bonus, if any, the benefits (the "BENEFITS") generally
     available to the executives of the Corporation, such benefits to be
     provided in accordance with, to the extent permitted by and subject to the
     terms and conditions of the applicable fund, plan or arrangement relating
     thereto in effect from time to time. The Corporation acknowledges that the
     Executive shall be subject to the provisions of the Corporation's liability
     insurance for directors and officers as same may be in effect from time to
     time.

5.4. Pro-Rata Entitlement in First Year of Employment, Notwithstanding sections
     5.1 and 5.2 hereof (i) the Basic Salary shall be prorated in respect of the
     First Year of Employment such that the Executive shall be entitled to
     receive and the Corporation shall be required to pay in respect of such
     year only that proportion of the Basic Salary that the number of days in
     the First Year of Employment is to 365; and (ii) any bonus payable in
     respect of the First Year of Employment shall be awarded in the sole
     discretion of the Board.

5.5. Pro-Rata Entitlement in the Event of Termination. If the Executive's
     employment is terminated pursuant to section 8.1.1, 8.1.2, or 8.1.3, bonus,
     if any, will be payable at the board's discretion.

     If the Executive dies or retires during the Employment Period, the
     Executive shall be entitled to receive in respect of his entitlement to
     bonus remuneration and the Corporation shall be required to pay in respect
     thereof, only that proportion of the bonus remuneration in respect of the
     year of employment at which the effective date of the termination of
     employment or the date of death occurs that the number of days elapsed from
     the commencement of such year of employment to the effective date of
     termination or the date of death is to 365, provided that said bonus shall
     be equal to or greater than 66% of the bonus remuneration the Executive
     earned in the year proceeding termination.


6.   EXPENSES & CAR ALLOWANCE

     The Corporation shall pay or reimburse the Executive for all travel and
out-of-pocket expenses reasonably incurred or paid by the Executive in the
performance of his duties and responsibilities upon presentation of expense
statements or receipts or such other supporting documentation as the Corporation
may reasonably require. All travel and other expenses incurred by the Executive
shall be in accordance with the Corporation's travel and expense policies.

In accordance with the Corporation's current policy governing the provision of
automobiles to executive personnel, the Corporation shall provide the Executive
with a monthly car allowance payable in periodic equal instalments in accordance
with the practices of the Corporation applicable to its other senior executives.




                                      -6-


7.   VACATION

The Executive shall be entitled while employed by the Corporation to four weeks
vacation with pay per year. Vacation shall be taken by the Executive at such
time as may be acceptable to the Corporation having regard to its operations and
no more than two (2) weeks of vacation shall be taken consecutively. If the
Executive has not taken the full vacation to which the Executive is entitled in
any calendar year, the Executive will be paid at the end of such calendar year
Basic Salary in respect of the accrued unused vacation. Except as required under
the ESA, the Executive shall not be entitled to carry over any unused portion of
vacation to the following calendar year and will lose the entitlement to such
unused portion. Notwithstanding the foregoing, in the event that the Executive's
employment is terminated pursuant to section 8, the Executive shall not be
entitled to receive any payment in lieu of any accrued unused vacation except to
the extent, if any, required by the ESA.

8.   TERMINATION

8.1. Notice. The Executive's employment shall terminate or be terminable:

     8.1.1. by the Executive on one (1) months prior written notice to the
     Corporation;

     8.1.2. by the Corporation at any time without prior notice and, subject to
     the provisions of the ESA and the Human Rights Code (Ontario), without
     further obligation to the Executive for reasons of Just Cause or because of
     the occurrence of Disability;

     8.1.3. by the Corporation, for any reason other than for Just Cause or
     Disability, at any time without prior notice and without further obligation
     to the Executive other than those obligations of the Corporation set out in
     section 9 of this Agreement;

     8.1.4. upon the death of the Executive; and

     8.1.5. upon the Retirement of the Executive.

8.2. Effective Date. The effective date on which the Executive's employment
     shall be terminated shall be:

     8.2.1. in the case of termination pursuant to section 8.1.1, the last day
     of the one (1) month period set out in the notice;

     8.2.2. in the case of termination pursuant to sections 8.1.2 and 8.1.3, the
     day the Executive is deemed, under section 12 to have received notice from
     the Corporation of such termination;

     8.2.3. in the event of the death of the Executive, on the date of his
     death; and

     8.2.4. in the event of the Retirement of the Executive, on the date of his
     Retirement.


                                      -7-


9.   PAYMENTS ON TERMINATION OF EMPLOYMENT

     (a)  If the Executive's employment is terminated as a result of Termination
          Without Cause, the Corporation shall (subject to the Executive's
          obligations contained herein):

          (i)   for a period of 12 months from the effective date of Termination
                Without Cause make the following payments (collectively referred
                to herein as the "SEVERANCE AMOUNT") to the Executive. In
                addition, the period of termination payments and benefits shall
                be extended by one month for each additional year of employment
                completed by the Executive commencing January 1,2004:

                  (I)   payments to the Executive in the same amount and on the
                        same basis as the Basic Salary being paid to the
                        Executive immediately prior to the effective date of
                        termination; and

                  (II)  continue to provide the Executive with Benefits, in
                        accordance with, and to the extent permitted by and
                        subject to the terms and conditions of the applicable
                        fund, plan or arrangement relating thereto;

                  (III) car allowance in accordance with Article 6;

                  (IV)  payment to the Executive up to a maximum of $10,000.00
                        to cover all costs associated with career relocation and
                        outplacement services obtained by the Executive, upon
                        presentation of receipts.

          (ii)  all payments made to the Executive shall be subject to
                applicable deductions and withholdings and shall be in full
                satisfaction of any and all entitlement that the Executive may
                have to notice of termination or payment in lieu thereof,
                severance pay and any other payments to which the Executive may
                otherwise be entitled to pursuant to ESA and any other
                applicable law. The Corporation shall cooperate with the
                Executive with respect to the payment of all payments due on
                termination such that the Executive shall be entitled to obtain
                the benefit of any tax shelters or strategies that may be
                available or may become available;

          (iii) notwithstanding any other provisions in this Agreement, the
                exercise of the Executive's options will be in accordance with
                the terms of the Viventia Biotech Inc. Share Option Plan;

          (iv)  if, following Termination Without Cause, the Executive breaches
                any of the provisions of the Confidential Information,
                Intellectual Property, Non-Competition and Non-Solicitation
                Agreement (attached as Appendix A), the Executive shall not be
                eligible, as of the date of such breaches for any Severance
                Amount and all obligations of the Corporation to pay the




                                      -8-


               Executive the Severance Amount shall (subject to applicable
               minimum amounts payable pursuant to the ESA) cease.


10.  REMEDIES

     The Executive acknowledges that a breach or threatened breach by the
Executive of the provisions of the Confidential Information, Intellectual
Property, Non-Competition and Non-Solicitation Agreement will result in the
Corporation and its shareholders suffering irreparable harm which is not capable
of being calculated and which cannot be fully or adequately compensated by the
recovery of damages alone. Accordingly, the Executive agrees that the
Corporation shall be entitled to interim and permanent injunctive relief,
specific performance and other equitable remedies, in addition to any other
relief to which the Corporation may become entitled.


11.  CO-OPERATION BY EXECUTIVE

     The Executive shall co-operate in all respects with the Corporation if the
question arises as to whether a Disability has occurred. Without limiting the
generality of the foregoing, the Executive shall authorize the Executive's
medical doctor or other health care specialist to discuss the condition of the
Executive with the Corporation and shall submit to examination by a medical
doctor or other health care specialist selected by the Corporation.


12.  NOTICES

     Any notice or other communication required or permitted to be given
hereunder shall be in writing and shall be given by prepaid first-class mail, by
facsimile or other means of electronic communication or by hand-delivery as
hereinafter provided. Any such notice or other communication, if mailed by
prepaid first-class mail at any time other than during a general discontinuance
of postal service due to strike, lockout or otherwise, shall be deemed to have
been received on the fourth Business Day after the post-marked date thereof, or
if mailed by registered mail, shall be deemed to have been received on the day
such mail is delivered by the post office, or if sent by facsimile or other
means of electronic communication, shall be deemed to have been received on the
Business Day following the sending, or if delivered by hand shall be deemed to
have been received at the time it is delivered to the applicable address noted
below either to the individual designated below or to an individual at such
address having apparent authority to accept deliveries on behalf of the
addressee. Notice of change of address shall also be governed by this section.
In the event of a general discontinuance of postal service due to strike,
lock-out or otherwise, notices or other communications shall be delivered by
hand or sent by facsimile or other means of electronic communication and shall
be deemed to have been received in accordance with this section. Notices and
other communications shall be addressed as follows:

if to the Executive:

         Mr. Michael A. Byrne
         2049 Burbank Drive




                                      -9-


         Mississauga, Ontario
         L5L 2T6


 if to the Corporation:

         Viventia Biotech Inc.
         10 Four Seasons Place
         Suite 501
         Toronto, Ontario
         M9B 6H7




                             
Attention:                      President and Chief Executive Officer
Telecopier number:              (416) 335-9306



13.  HEADINGS

     The inclusion of headings in this Agreement is for convenience of reference
only and shall not affect the construction or interpretation hereof.


14.  INVALIDITY OF PROVISIONS

     Each of the provisions contained in this Agreement is distinct and
severable and a declaration of invalidity or unenforceability of any such
provision by a court of competent jurisdiction shall not affect the validity or
enforceability of any other provision hereof.


15.  ENTIRE AGREEMENT

     This Agreement constitutes the entire agreement between the parties
pertaining to the subject matter of this Agreement. This Agreement supersedes
and replaces all prior agreements, if any, written or oral, with respect to the
Executive's employment by the Corporation and any rights which the Executive may
have by reason of any such prior agreement or by reason of the Executive's prior
employment, if any, by the Corporation. There are no warranties, representations
or agreements between the parties in connection with the subject matter of this
Agreement except as specifically set forth or referred to in this Agreement. No
reliance is placed on any representation, opinion, advice or assertion of fact
made by the Corporation or its directors, officers and agents to the Executive,
except to the extent that the same has been reduced to writing and included as a
term of this Agreement. Accordingly, there shall be no liability, either in tort
or in contract, assessed in relation to any such representation, opinion, advice
or assertion of fact, except to the extent aforesaid.





                                      -10-


16.  WAIVER, AMENDMENT

     Except as expressly provided in this Agreement, no amendment or waiver of
this Agreement shall be binding unless executed in writing by the party to be
bound thereby. No waiver of any provision of this Agreement shall constitute a
waiver of any other provision nor shall any waiver of any provision of this
Agreement constitute a continuing waiver unless otherwise expressly provided.


17.  GOVERNING LAW

     This Agreement shall be governed by and construed in accordance with the
laws of the Province of Ontario and the laws of Canada applicable therein.


18.  COUNTERPARTS

     This Agreement may be signed in counterparts and each of such counterparts
shall constitute an original document and such counterparts, taken together,
shall constitute one and the same instrument.





                                      -11-




19.  ACKNOWLEDGEMENT

          The Executive acknowledges that:

19.1. the Executive has had sufficient time to review and consider this
      Agreement thoroughly;

19.2. the Executive has read and understands the terms of this Agreement and the
      Executive's obligations hereunder;

19.3. the Executive has been given an opportunity to obtain independent legal
      advice, or such other advice as the Executive may desire, concerning the
      interpretation and effect of this Agreement; and

19.4. this Agreement is entered into voluntarily and without any pressure.


          IN WITNESS WHEREOF the parties have executed this Agreement.


                           )    VIVENTIA BIOTECH INC.
                           )
                           )
                           )
                           )
                           )
                           )    By:             /s/ Nick Glover
                                   ---------------------------------------------
                                Name:   Nick Glover
                                Title:  President and Chief
                                        Executive Officer

                                I/We have the authority to bind the corporation






SIGNED, SEALED AND DELIVERED
     in the presence of


/s/                                         /s/ Michael A. Byrne
- -------------------------------------       ------------------------------------
Witness                                     Michael A. Byrne





                              VIVENTIA BIOTECH INC.

                CONFIDENTIAL INFORMATION, INTELLECTUAL PROPERTY,
                 NON-COMPETITION AND NON-SOLICITATION AGREEMENT

     In consideration of my employment with Viventia Biotech Inc. ("VIVENTIA"),
I acknowledge, understand and agree with Viventia as follows:

1.   PROTECTION OF CONFIDENTIAL INFORMATION.

All Confidential Information (as defined in paragraph 2 below) whether it is
developed by me or by others employed or engaged by or associated with Viventia,
is the exclusive and confidential property of Viventia and will at all times be
regarded, treated and protected as such, as provided in this Agreement. Failure
to mark any written material as confidential will not affect the confidential
nature of such written material or the information contained therein.

2.   DEFINITION OF CONFIDENTIAL INFORMATION.

"CONFIDENTIAL INFORMATION" means all information, intellectual property
(including trade secrets) and facts, relating to and used or proposed to be used
in the business of Viventia and its affiliates, acquired by the Executive during
any period in which the Executive was affiliated with Viventia in the capacity
of an Executive, director or shareholder which is confidential based upon its
nature or the circumstances surrounding its disclosure, and includes, without
limiting the generality of the foregoing information:

     (i)   relating to Viventia's or an affiliate's products and services or to
           Viventia's or an affiliate's research and development projects or
           plans;

     (ii)  relating to Viventia's or an affiliate's trade secret, technology,
           patentable and unpatentable inventions, discoveries, processes, test
           procedures and results, records, specifications, data formulations,
           formulas, know-how, samples, specimens, manufacturing processes and
           regulatory information; or

     (iii) relating to Viventia's or an affiliate's business policies,
           strategies, operations, finances, plans or opportunities, including
           the identity of, or particulars about, Viventia's or an affiliate's
           clients or suppliers.

3.   EXCLUSIONS FROM CONFIDENTIAL INFORMATION.

"CONFIDENTIAL INFORMATION" will not include information publicly known that is
generally used by persons in my current position with Viventia, and the general
skills and experience gained during my employment with or engagement by Viventia
which I could reasonably have been expected to acquire in similar employment
with or engagement by other companies. The phrase "PUBLICLY KNOWN" shall mean
readily accessible to the public in written publications without breach of this
or similar agreements. The burden of proving that information or skills and
experience are Confidential Information shall be on the party asserting such
exclusion. "CONFIDENTIAL INFORMATION" shall also not include information the
disclosure of which is






                               Appendix A - Page 2


required to be made by any law, regulation, governmental authority or court,
provided that before disclosure is made, notice of the requirement is provided
to Viventia, and (to the extent possible in the circumstances) Viventia is
afforded an opportunity to dispute the requirement.

4.   COVENANTS RESPECTING CONFIDENTIAL INFORMATION.

As a consequence of my acquisition of Confidential Information, I will occupy a
position of trust and confidence with respect to Viventia's affairs and
business. In view of the foregoing and of the consideration to be provided to me
by Viventia, I agree that it is reasonable and necessary for me to make the
following covenants regarding my conduct during and subsequent to my employment
with or engagement by Viventia. I hereby agree as follows:

     (i)  Non-Disclosure. During and after my employment with or engagement by
          Viventia, I will not disclose Confidential Information to any person
          or entity other than as necessary in carrying out my duties on behalf
          of Viventia, without first obtaining Viventia 's consent, and I will
          take all reasonable precautions to prevent inadvertent disclosure of
          such Confidential Information. This prohibition against disclosure of
          Confidential Information includes, but is not limited to, disclosing
          the fact that any similarity exists between the Confidential
          Information and information independently developed by another person
          or entity, and I understand that such similarity does not excuse me
          from abiding by my covenants and other obligations under this
          Agreement.

     (ii) Using. Copying, etc. During and after my employment with or engagement
          by Viventia, I will not use, copy, transfer or destroy any
          Confidential Information other than as necessary in carrying out my
          duties on behalf of Viventia, without first obtaining Viventia 's
          consent, and I will take all reasonable precautions to prevent
          inadvertent use, copying, transfer or destruction of any Confidential
          Information. The prohibition against my use, copying, transfer or
          destruction of Confidential Information includes, but is not limited
          to, licensing or otherwise exploiting, directly or indirectly, any
          products or services (including software in any form) which embody or
          are derived from Confidential Information, or exercising judgment or
          performing analysis based upon knowledge of Confidential Information.

5.   INTELLECTUAL PROPERTY RIGHTS.

I agree to disclose to Viventia all information relating to Intellectual
Property (as defined below) prior to any public disclosure thereof, including
but not limited to the nature of the Intellectual Property, production data,
technical and engineering data, test data and test results, the status and
details of research and development of products and services, and information
regarding acquiring, protecting, enforcing and licensing proprietary rights
developed by me during my employment with Viventia, either individually or in
collaboration with others, which relates directly or indirectly to the business
of Viventia. I acknowledge and agree that all right, title and interest
whatsoever in and to the Intellectual Property, including the foregoing and any
copyright, is and will be the exclusive property of Viventia and it will have
absolute discretion to determine how such Intellectual Property is used. All
work done while I am employed by Viventia is a






                               Appendix A - Page 3


work for hire under which Viventia is the first owner for copyright purposes and
any and all copyright will vest in Viventia. I hereby waive all moral rights
that I may have in the Intellectual Property and agree that this waiver may be
invoked by Viventia, and by any of its authorized agents or assignees, to use
any of the Intellectual Property. I agree that, in performing my duties as an
Executive of Viventia, I will not use or disclose any information that is
confidential to any third party or that is subject to the copyright, patent,
trade secret, or topography, rights of any third party. I agree to execute all
such instruments and do all such things as may be reasonably necessary or
desirable to give full effect to the foregoing and will cooperate and assist
Viventia in enforcing its rights under this paragraph.

"INTELLECTUAL PROPERTY" means all legally recognized rights, including patents,
copyrights, trade marks, topographies, and trade secrets which result or derive
from my services provided to Viventia or with the knowledge or use of
Confidential Information, and includes, but is not limited to developments,
inventions, designs, works of authorship, improvements and ideas, whether or not
patentable or copyrightable, conceived or made by me (individually or in
collaboration with others) during my employment with Viventia or which result
from or derive from Viventia's resources or which are reasonably related to the
business of Viventia.

6.   NON-SOLICITATION.

(a)  No Solicitation of Customers, Clients and Suppliers.


     I acknowledge the importance to the business carried on by Viventia of the
     customer, client and supplier relationships developed by it and the unique
     opportunity that my employment and my access to the Confidential
     Information offers to interfere with these relationships. Accordingly, I
     will not while employed or engaged by Viventia and for 12 months
     thereafter, directly or indirectly, contact or solicit any person who I
     know to be a prospective, current or former customer, client or supplier of
     Viventia for the purpose of selling to the customer or client or buying
     from the supplier any products or services that are the same as or
     substantially similar to, or in any way competitive with, the products or
     services sold or purchased by Viventia during my employment or at the end
     thereof, as the case may be.

(b)  No Solicitation.

     I acknowledge the importance to the business carried on by Viventia of the
     human resources engaged and developed by it and the unique access my
     employment offers to interfere with these resources. Accordingly, I will
     not while employed or engaged by Viventia and for 12 months thereafter,
     hire, engage or retain or induce or solicit, attempt to induce or solicit
     or assist any third party in hiring, engaging or retaining or inducing or
     soliciting any employee or consultant of the Company, to leave the Company
     or to accept employment or engagement elsewhere.






                               Appendix A - Page 4


7.   NON-COMPETITION.

I will not, while employed or engaged by Viventia directly or indirectly, in any
manner whatsoever including either individually, or in partnership, jointly or
in conjunction with any other person, or as principal, agent, owner, consultant,
contractor, Executive, officer, director, advisor or shareholder:

     (i)   be engaged in any undertaking;

     (ii)  have any financial or other interest (including an interest by way of
           royalty or compensation arrangements) in or in respect of the
           business of any person which carries on a business; or

     (iii) advise, render or provide services to, lend money to or guarantee the
           debts or obligations of any person that carries on a business;

in any province of Canada or any state of the United States, if, at the relevant
time, Viventia is carrying on business in such province or state, which is a
Competitive Business (as defined below).

"COMPETITIVE BUSINESS" means any Bio-Pharmaceutical Business in Canada and the
United States.

8.   CERTAIN WARRANTIES, COVENANTS AND REMEDIES.

(a)  I agree that my obligations as set forth in this Agreement will commence as
     of the date on which I was first employed by Viventia.

(b)  I acknowledge that a breach by me of this Agreement will result in
     Viventia, its affiliates and shareholders suffering irreparable harm which
     is not capable of being calculated and which cannot be fully or adequately
     compensated by the recovery of damages alone. Accordingly, I agree that
     Viventia will be entitled to interim and permanent injunctive relief,
     specific performance and other equitable remedies, in addition to any other
     relief to which Viventia may become entitled if I breach or threaten to
     breach this Agreement.

(c)  My obligations under this Agreement are to remain in effect in accordance
     with each of their terms and will exist and continue in full force and
     effect notwithstanding any breach or repudiation, or alleged breach or
     repudiation, of this Agreement or my employment agreement by Viventia.

9.   BINDING EFFECT.

This Agreement shall be binding on me and my heirs, executors and legal
representatives.

10.  GOVERNING LAWS.

This Agreement shall be governed by the laws in force in the Province of
Ontario.





                               Appendix A - Page 5


11.  OTHER AGREEMENTS.

This Agreement is supplemental to and separate from the agreement under which I
am employed or engaged by Viventia. However, if there is any conflict or
inconsistency between the provisions of such other agreement and this Agreement,
the provisions of this Agreement will govern and prevail.


     IN WITNESS WHEREOF, I have signed and sealed this Agreement as of the date
set forth below.

SIGNED, SEALED AND DELIVERED
    in the presence of





  /s/                                       /s/ Michael A. Byrne
- -------------------------------------       ------------------------------------
Witness                                     Michael A. Byrne