ARONEX PHARMACEUTICALS, INC.
                                                              Exhibit 11.1

             Statement Regarding Computation of Per Share Earnings

The following  reflects the information used in calculating the number of shares
in the  computation  of net loss per share for each of the  periods set forth in
the Statements of Operations.



                                                                                         Average                      Loss
                                                       Days          Shares              Shares                        Per
                                      Shares        Outstanding      X Days            Outstanding      Loss          Share
                                                                                                   

Quarter Ended June 30, 1995:          5,232,463         53          277,320,513
                                      5,233,599         38          198,876,743
                                                        91          476,197,256   /91   5,291,081      (1,943,000)    (0.37)

Six Months Ended June 30, 1995:       5,202,476          2           10,404,951
                                      5,214,976          2           10,429,951
                                      5,221,604         82          428,171,528
                                      5,232,463          4           20,929,850
                                      5,232,463         53          277,320,513
                                      5,233,599         38          198,876,743
                                                       181          946,133,536  /181   5,227,257      (3,952,000)    (0.76)

Quarter Ended June 30, 1996:         10,847,725          5           54,238,623
                                     10,848,023          7           75,936,158
                                     10,849,767          3           32,549,301
                                     10,851,626          1           10,851,626
                                     10,858,605          2           21,717,209
                                     10,862,095          1           10,862,095
                                     10,962,004          4           43,848,014
                                     10,962,593          2           21,925,185
                                     10,965,241          1           10,965,241
                                     10,965,939          6           65,795,631
                                     10,967,993          5           54,839,963
                                     10,972,354          2           21,944,708
                                     10,977,354          7           76,841,478
                                     10,978,310          4           43,913,240
                                     10,983,980          1           10,983,980
                                     10,989,215          1           10,989,215
                                     13,992,587          1           13,992,587
                                     13,996,077          6           83,976,459
                                     13,996,949          1           13,996,949
                                     14,446,949          5           72,234,745
                                     14,453,492          5           72,267,460
                                     14,456,109          1           14,456,109
                                     14,465,806          2           28,931,612
                                     14,472,786          1           14,472,786
                                     14,473,658          3           43,420,974
                                     14,478,658          1           14,478,658
                                     14,481,500          3           43,444,499
                                     14,483,680          1           14,483,680
                                     14,484,059          2           28,968,118
                                     14,485,899          3           43,457,696
                                     14,488,079          3           43,464,237
                                     14,526,802          1           14,526,802
                                                        91        1,128,775,033   /91  12,404,121      (2,327,000)    (0.19)


                                                                    Continued

WOD01:1996.1





                          ARONEX PHARMACEUTICALS, INC.
                                                               Exhibit 11.1
                                                                  Contnued



                                                                                         Average                      Loss
                                                       Days          Shares              Shares                        Per
                                      Shares        Outstanding      X Days            Outstanding      Loss          Share
                                                                                                   

Six Months Ended June 30, 1996:      10,847,725          1           10,847,725
                                     10,848,023          5           54,240,113
                                     10,849,767          7           75,948,369
                                     10,851,626          3           32,554,877
                                     10,858,605          1           10,858,605
                                     10,862,095          2           21,724,189
                                     10,962,004          1           10,962,004
                                     10,962,593          4           43,850,370
                                     10,965,241          2           21,930,482
                                     10,965,939          1           10,965,939
                                     10,967,993          6           65,807,955
                                     10,927,354          5           54,861,770
                                     10,977,354          2           21,954,708
                                     10,978,310          7           76,848,170
                                     10,983,980          4           43,935,920
                                     10,989,215          1           10,989,215
                                     13,992,587          1           13,992,587
                                     13,996,077          1           13,996,077
                                     13,996,949          6           83,981,694
                                     14,446,949          1           14,446,949
                                     14,453,492          5           72,267,460
                                     14,456,109          5           72,280,545
                                     14,465,806          1           14,465,806
                                     14,472,786          2           28,945,571
                                     14,473,658          1           14,473,658
                                     14,478,658          3           43,435,974
                                     14,481,500          1           14,481,500
                                     14,483,680          3           43,451,040
                                     14,484,059          1           14,484,059
                                     14,485,899          2           28,971,797
                                     14,488,079          3           43,464,237
                                     14,526,802          3           43,580,405
                                     10,380,056          1           10,380,056
                                     10,390,003         10          103,900,030
                                     10,409,608          4           41,638,432
                                     10,418,676          2           20,837,351
                                     10,478,786          1           10,478,786
                                     10,046,458          3           30,139,374
                                     10,598,792          1           10,598,792
                                     10,678,561          2           21,357,121
                                     10,680,653          1           10,680,653
                                     10,680,903          3           32,042,709
                                     10,710,132          4           42,840,526
                                     10,718,504          6           64,311,024
                                     10,727,170          4           42,908,678
                                     10,728,565          1           10,728,565
                                     10,729,263          1           10,729,263
                                     10,729,394          7           75,105,758
                                     10,731,487         19          203,898,253
                                     10,742,559          7           75,197,913
                                     10,771,115          2           21,542,230
                                     10,775,477          2           21,550,954
                                     10,776,991          4           43,107,962
                                     10,784,842          1           10,784,842
                                     10,812,921          1           10,812,921
                                     10,832,546          2           21,665,092
                                     10,847,725          2           21,695,449
                                                       182        2,097,932,497  /182   11,527,102     (4,400,000)(0.38)