EXHIBIT 10.79

                           TERMINATION AND RELEASE
                        OF PATENT SECURITY AGREEMENT
                           (United States Patents)

      TERMINATION AND RELEASE OF PATENT SECURITY AGREEMENT, dated as of May
30, 2002, by and between AMERICAN CAPITAL STRATEGIES, LTD., a Delaware
corporation, with offices at Two Bethesda Center-14th Floor, Bethesda,
Maryland 20814, (the "Lender") and IGI, INC., a Delaware corporation,
having its principal place of business at 105 Lincoln Avenue, Buena, New
Jersey 08310 (the "Company").

      WHEREAS, pursuant to the terms of (i) the Note and Equity Purchase
Agreement, dated October 29, 1999, between the Company, IGEN, Inc., Blood
Cells, Inc. and Immunogenetics, Inc. (collectively the "Borrowers") and the
Lender, as amended and in effect from time to time (the "Purchase
Agreement"), and (ii) the Patent Security Agreement dated October 29, 1999,
between the Company and the Lender, as amended and in effect from time to
time (the "Patent Agreement"), each for the purpose of securing certain
obligations of the Company to the Lender;

      WHEREAS, pursuant to the Purchase Agreement and the Patent Agreement,
the Company granted to the Lender, a security interest in and lien on, and
collaterally assigned to the Lender, all of its patents and patent
applications, as well as all its rights under all License Agreements to all
patents licensed to the Company thereunder, including without limitation,
the patents, patent applications and license rights identified on Exhibits
A, B and C attached hereto, (hereinafter collectively referred to as the
"Named Patents"); and

      WHEREAS, the Lender has agreed to terminate and release its security
interest and all of its right, title and interest in each of the Named
Patents as herein provided;

      NOW, THEREFORE, for good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the Lender and the Company
hereby agree as follows:

      1.    Release and Assignment.  The Lender hereby terminates and
releases its security interest in and lien on all of the Company's Named
Patents and the Lender hereby assigns and transfers to the Company, without
recourse, all of the Lender's right, title and interest in and to each of
the Named Patents effective as of the date set forth above.

      2.    Acknowledgment and Acceptance.  The Company hereby acknowledges
and accepts the foregoing release and assignment by the Lender.

      3.    Counterparts.  This Release may be executed in any number of
counterparts which shall together constitute one and the same agreement.


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      IN WITNESS WHEREOF, the Lender and the Company have executed this
Release, to take effect as of the date first set forth above.

                                       AMERICAN CAPITAL STRATEGIES, LTD.

                                       By:  /s/ Ira J. Wagner
                                            -------------------------------
                                            Name:  Ira Wagner
                                            Title: EVP & COO

Accepted:

IGI, INC.

By:
     -------------------------------
     Name:  Domenic Golato
     Title: Sr. Vice President & CFO

                        CERTIFICATE OF ACKNOWLEDGMENT

STATE OF MARYLAND        )
                         )ss.
COUNTY OF PRINCE GEORGES )

      Before me, the undersigned, a Notary Public in and for the county
aforesaid, on this 31 day of May, 2002, personally appeared Ira Wagner to
me known personally, and who, being by me duly sworn, deposes and says that
he is THE COO of AMERICAN CAPITAL STRATEGIES, LTD., and that said
instrument was signed and sealed on behalf of said corporation by authority
of its Board of Directors, and said officer acknowledged said instrument to
be the free act and deed of said corporation.

                                       /s/  Samantha Blizzard
                                       ------------------------------------
                                       Notary Public
                                       My Commission Expires:

                                       Samantha L. Blizzard
                                       My Commission Expires On
                                       December 1, 2002


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      IN WITNESS WHEREOF, the Lender and the Company have executed this
Release, to take effect as of the date first set forth above.

                                       AMERICAN CAPITAL STRATEGIES, LTD.

                                       By:
                                            -------------------------------
                                            Name:
                                            Title:

Accepted:

IGI, INC.

By:  /s/  Domenic Golato
     -------------------------------
     Name:  Domenic Golato
     Title: Sr. Vice President & CFO

                        CERTIFICATE OF ACKNOWLEDGMENT

STATE OF MARYLAND        )
                         )ss.
COUNTY OF ______________ )

      Before me, the undersigned, a Notary Public in and for the county
aforesaid, on this ___ day of May, 2002, personally appeared _________ to
me known personally, and who, being by me duly sworn, deposes and says that
he is a ________ of AMERICAN CAPITAL STRATEGIES, LTD., and that said
instrument was signed and sealed on behalf of said corporation by authority
of its Board of Directors, and said officer acknowledged said instrument to
be the free act and deed of said corporation.


                                       ------------------------------------
                                       Notary Public
                                       My Commission Expires:


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                   SCHEDULES TO PATENT SECURITY AGREEMENT
                   BETWEEN IGI, INC. AND AMERICAN CAPITAL


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                                 SCHEDULE A
                                 ----------

                              IGI, INC. PATENTS
                              -----------------

None


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                                 SCHEDULE B
                                 ----------

         PATENTS LICENSED TO IGI, INC. BY TRISTRATA TECHNOLOGY, INC.
         -----------------------------------------------------------


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                               Schedule 7.1.16
                     Intellectual Property Licensed from
                         Tristrata Technology, Inc.

                             ISSUED U.S. PATENTS

1.    U.S. Patent Reexamination Certificate Bl 5,091,171

2.    U.S. Patent No. 5,385,938

3.    U.S. Patent No. 5,389,677

                          U.S. PATENT APPLICATIONS

1.    U.S. Patent Application No. 06/945,680

2.    U.S. Patent Application No. 07/469,738

3.    U.S. Patent Application No. 07/812,858

4.    U.S. Patent Application No. 08/008,223

5.    U.S. Patent Application No. 07/393,749

6.    U.S. Patent Application No. 08/359,939

7.    U.S. Patent Application No. 07/840,149

8.    U.S. Patent Application No. 07/683,437

9.    U.S. Patent Application No. 07/936,863

10.   U.S. Patent Application No. 08/117,559

11.   Those portions of any other U.S. Patents or U.S. Patent Applications
      owned or controlled by LICENSOR at any time during the term of this
      Agreement relating to glycolic acid and/or its salts, to the extent
      the portions of such other U.S. Patents or U.S. Patent Applications
      encompass a method for using only glycolic acid and/or its salts for
      the treatment of human skin wrinkles, fine lines on the human skin
      and/or aging related human skin changes.


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                                 SCHEDULE C
                                 ----------

1.    License Agreement dated January 1, 1996, by and between Tristrata
Technology, Inc. and IGI, Inc.


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