Exhibit 32.1

                          CERTIFICATION PURSUANT TO
                           18 U.S.C. SECTION 1350,
                              AS ENACTED UNDER
                SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
                ---------------------------------------------

In connection with the Annual Report of IGI, Inc. (the "Company") on Form
10-K for the year ended December 31, 2004, as filed with the Securities and
Exchange Commission on the date hereof (the "Report"), I, Frank Gerardi,
Chairman and Chief Executive Officer of the Company, state and certify,
pursuant to 18 U.S.C. Section  1350, as enacted under Section  906 of the
Sarbanes-Oxley Act of 2002, that:

      (1) The Report fully complies with the requirements of Section 13(a)
or 15(d) of the Securities Exchange Act of 1934; and

      (2) The information contained in the Report fairly presents, in all
material respects, the financial condition and result of operations of the
Company as of December 31, 2004.

Date:  April 12, 2005

                                       /s/ Frank Gerardi
                                       -----------------
                                       Frank Gerardi
                                       Chairman and Chief Executive Officer