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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

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                                    FORM 8-K

                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

        Date of report (Date of earliest event reported): OCTOBER 7, 2005

                        COMMISSION FILE NUMBER 000-15862

                                GVC VENTURE CORP.
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             (Exact name of registrant as specified in its charter)

                                    DELAWARE
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                 (State or other jurisdiction of incorporation)

                                   13-3018466
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                        (IRS Employer Identification No.)



 The Chrysler Building, 405 Lexington Avenue, Suite 2600, New York, NY   10174
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                    (Address of principal executive offices)

        Registrant's telephone number including area code: (212) 907-6610

                                 NOT APPLICABLE
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          (Former name or former address, if changed since last report)

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ITEM 1.01  ENTRY INTO A MATERIAL DEFINITIVE AGREEMENT.

         On June 27, 2005,  the Company  entered  into an Agreement  and Plan of
Merger (the "Merger Agreement") by and among the Company, GVC Acquisition Corp.,
a Delaware corporation and wholly owned subsidiary of the Company  ("MergerCo"),
and Cougar Biotechnology,  Inc., a Delaware corporation ("Cougar"),  pursuant to
which  MergerCo is to merge with and into Cougar,  with Cougar  remaining as the
surviving corporation and becoming a wholly owned subsidiary of the Company (the
"Merger").  The Merger and  Merger  Agreement  are  discussed  in the  Company's
Current Report on Form 8-K dated (date of earliest event reported) June 27, 2005
filed by the Company with the  Securities  and Exchange  Commission  on June 28,
2005, and the Merger Agreement was filed as Exhibit 2.1 to that Report.

         On October 7, 2005,  the Company,  MergerCo  and Cougar  entered into a
First Amendment to the Merger Agreement  pursuant to which,  among other things,
Cougar agreed to increase the cash payment  payable to the Company under Section
8.1(g) of the Merger  Agreement to $10,000 for each month beyond  September  30,
2005 that Cougar elects to extend the termination date of the Merger  Agreement.
Notwithstanding  the  foregoing,  Cougar  may not,  without  the  consent of the
company, extend the termination date of the Merger Agreement beyond December 31,
2005. A copy of the First Amendment to the Merger  Agreement is attached to this
Report as Exhibit 2.1(b), is incorporated  herein by reference and the foregoing
is qualified in its entirety by reference to the full text thereof.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS.

         (a)      Financial statements of business acquired:

                  None.

         (b)      Pro forma financial information:

                  None.

         (c)      Exhibits:

                  2.1(a)   Agreement and Plan of Merger (the "Merger Agreement")
                           dated as of June 27,  2005 by and among the  Company,
                           GVC  Acquisition  Corp., a Delaware  corporation  and
                           wholly owned subsidiary of the Company  ("MergerCo"),
                           and   Cougar   Biotechnology,    Inc.,   a   Delaware
                           corporation ("Cougar").  Incorporated by reference to
                           Exhibit 2.1 to the Company's  current  Report on Form
                           8-K dated (date of earliest event  reported) June 27,
                           2005, file No. 000-15862.

                  *2.1(b)  First  Amendment,  dated  October 7, 2005,  to Merger
                           Agreement  by and among  the  Company,  MergerCo  and
                           Cougar.


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         * Filed herewith.


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                                   SIGNATURES

         Pursuant to the  requirements  of Securities  Exchange Act of 1934, the
registrant  had duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.

Dated:  October 11, 2005

                             GVC VENTURE CORP.


                             By:  /s/ Bernard Zimmerman
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                                  Bernard Zimmerman
                                  Chairman of the Board of Directors, President,
                                  Chief Executive Officer and Treasurer


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                                  EXHIBIT INDEX

Exhibit Number    Description

 2.1(a)           Agreement and Plan of Merger (the "Merger Agreement") dated as
                  of June 27,  2005 by and among the  Company,  GVC  Acquisition
                  Corp., a Delaware  corporation and wholly owned  subsidiary of
                  the Company ("MergerCo"),  and Cougar  Biotechnology,  Inc., a
                  Delaware corporation ("Cougar").  Incorporated by reference to
                  Exhibit 2.1 to the Company's  current Report on Form 8-K dated
                  (date of earliest  event  reported)  June 27,  2005,  file No.
                  000-15862.

 *2.1(b)          First Amendment, dated October 7, 2005, to Merger Agreement by
                  and among the Company, MergerCo and Cougar.



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         * Filed herewith.




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