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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

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                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the

                         Securities Exchange Act of 1934

       Date of report (Date of earliest event reported): December 30, 2005
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                        Commission File Number 000-15862

                                GVC VENTURE CORP.
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             (Exact name of registrant as specified in its charter)

                                    Delaware
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                 (State or other jurisdiction of incorporation)

                                   13-3018466
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                        (IRS Employer Identification No.)

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   The Chrysler Building, 405 Lexington Avenue, Suite 2600, New York, NY 10174
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                    (Address of principal executive offices)

        Registrant's telephone number including area code: (212) 907-6610

                                 Not applicable
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          (Former name or former address, if changed since last report)

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Item 1.01 Entry into a Material Definitive Agreement.

         On June 27, 2005,  the Company  entered  into an Agreement  and Plan of
Merger (the "Merger Agreement") by and among the Company, GVC Acquisition Corp.,
a Delaware corporation and wholly owned subsidiary of the Company  ("MergerCo"),
and Cougar Biotechnology,  Inc., a Delaware corporation ("Cougar"),  pursuant to
which  MergerCo is to merge with and into Cougar,  with Cougar  remaining as the
surviving corporation and becoming a wholly owned subsidiary of the Company (the
"Merger").  The Merger and  Merger  Agreement  are  discussed  in the  Company's
Current Report on Form 8-K dated (date of earliest event reported) June 27, 2005
filed by the Company with the  Securities  and Exchange  Commission  on June 28,
2005, and the Merger Agreement was filed as Exhibit 2.1 to that Report.

         On October 7, 2005,  the Company,  MergerCo  and Cougar  entered into a
First  Amendment  (the "First  Amendment") to the Merger  Agreement  pursuant to
which, among other things, Cougar agreed to increase the cash payment payable to
the Company  under  Section  8.1(g) of the Merger  Agreement to $10,000 for each
month beyond  September  30, 2005 that Cougar  elects to extend the  termination
date of the Merger  Agreement.  Notwithstanding  the foregoing,  Cougar was not,
without the consent of the Company,  entitled to extend the termination  date of
the Merger  Agreement beyond December 31, 2005. The First Amendment is discussed
in the  Company's  Current  Report on Form 8-K  dated  (date of  earliest  event
reported)  October  7,  2005,  and a copy of the  First  Amendment  was filed as
Exhibit 2.1(b) to that Report.

         On December 30, 2005,  the Company,  MergerCo and Cougar entered into a
Second  Amendment to the Merger Agreement (the "Second  Amendment")  pursuant to
which (a) the  parties  agreed to extend the date after  which the  Company  may
terminate the Merger  Agreement  under  Section 8(g) of the Merger  Agreement to
January 31, 2006,  (b) Cougar is to pay the Company  $20,000,  of which  $10,000
represents the fee payable for extending the Merger  Agreement  through  January
31, 2006 and $10,000 represents an advance by Cougar of the fee payable by it in
the event the Company terminates the Merger Agreement in accordance with Section
8.1(g) thereof provided that such termination fee is to be returned to Cougar if
the Closing  under the Merger  Agreement  occurs on or prior to January 31, 2006
and (c) the parties  agreed to free each other from the covenant in Section 6.10
of the Merger  Agreement  to enable them to solicit or initiate  discussions  or
negotiations with others  concerning any merger,  sale of capital stock, sale of
substantial assets or other business  combination  provided that the Company may
not  execute a  definitive  agreement  or complete a business  combination  with
another person until the Merger Agreement has been terminated in accordance with
Section 8.1 of the Merger Agreement.  A copy of the Second Amendment is attached
to this Report as Exhibit 2.1(c),  is  incorporated  herein by reference and the
foregoing is qualified in its entirety by reference to the full text thereof.


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Item 9.01   Financial Statements and Exhibits.

       (a)  Financial statements of business acquired:

            None.

       (b)  Pro forma financial information:

            None.

       (c)  Exhibits:

            2.1(a)      Agreement  and Plan of Merger (the "Merger  Agreement"),
                        dated as of June 27, 2005, by and among the Company, GVC
                        Acquisition  Corp.,  a Delaware  corporation  and wholly
                        owned subsidiary of the Company ("MergerCo"), and Cougar
                        Biotechnology,  Inc., a Delaware corporation ("Cougar").
                        Incorporated   by   reference  to  Exhibit  2.1  to  the
                        Company's  Current  Report  on Form 8-K  dated  (date of
                        earliest  event   reported)  June  27,  2005,  File  No.
                        000-15862.

            2.1(b)      First  Amendment,  dated  October 7, 2005, to the Merger
                        Agreement by and among the Company, MergerCo and Cougar.
                        Incorporated  by  reference  to  Exhibit  2.1(b)  to the
                        Company's  Current  Report  on Form 8-K  dated  (date of
                        earliest  event  reported)  October  7,  2005,  File No.
                        000-15862.

            *2.1(c)     Second Amendment, dated December 30, 2005, to the Merger
                        Agreement  by  and  among  the  Company,  MergerCo.  and
                        Cougar.

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            * Filed herewith.

                                   SIGNATURES

         Pursuant to the  requirements  of Securities  Exchange Act of 1934, the
registrant  had duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.

Dated:  January 5, 2006

                             GVC VENTURE CORP.


                             By:  /s/ Bernard Zimmerman
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                                  Bernard Zimmerman
                                  Chairman of the Board of Directors, President,
                                  Chief Executive Officer and Treasurer

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                                  EXHIBIT INDEX

Exhibit Number    Description

2.1(a)      Agreement and Plan of Merger (the "Merger  Agreement"),  dated as of
            June 27, 2005, by and among the Company,  GVC  Acquisition  Corp., a
            Delaware  corporation  and wholly  owned  subsidiary  of the Company
            ("MergerCo"), and Cougar Biotechnology, Inc., a Delaware corporation
            ("Cougar").   Incorporated  by  reference  to  Exhibit  2.1  to  the
            Company's  Current  Report on Form 8-K dated (date of earliest event
            reported) June 27, 2005, File No. 000-15862.

2.1(b)      First  Amendment,  dated October 7, 2005, to the Merger Agreement by
            and  among  the  Company,  MergerCo  and  Cougar.   Incorporated  by
            reference to Exhibit 2.1(b) to the Company's  Current Report on Form
            8-K dated (date of earliest event  reported)  October 7, 2005,  File
            No. 000-15862.

*2.1(c)     Second  Amendment,  dated December 30, 2005, to the Merger Agreement
            by and among the Company, MergerCo. and Cougar.


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*Filed herewith.


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