Exhibit 99.1

                      OPHTHALMIC IMAGING SYSTEMS ANNOUNCES

               RECORD FOURTH QUARTER AND YEAR-END RESULTS FOR 2005

                                      - - -

  Company Reports 35% Increase in Operating Income and 21% Increase in Revenues
                                  for the Year

                                      - - -

                 5th Consecutive Year of Increased Profitability


      SACRAMENTO,  CALIF.,  MARCH 7, 2006 - Ophthalmic  Imaging  Systems (OTCBB:
      OISI) (OIS) today  reported  financial  results for the fourth quarter and
      fiscal year ended December 31, 2005.


      OIS  reported net revenue for the year ended  December 31, 2005  increased
      21% to $13,651,000 from $11,294,000 in 2004. Operating income for the year
      climbed  approximately  35% to  $1,890,000,  compared to $1,399,000 in the
      prior year.


      Net income for 2005 was  $1,755,000,  or $0.11 earnings per diluted share,
      compared to $1,705,000,  or $0.11 earnings per diluted share, in 2004. Net
      income in 2005,  excluding a tax benefit of $53,000,  was  $1,702,000,  an
      increase of 48% compared to net income in 2004 of $1,147,000,  excluding a
      tax benefit of $558,000.


      The Company  reported net revenue of $4,142,000  for the fourth quarter of
      2005 compared with net revenues of  $3,523,000  for the fourth  quarter of
      2004, an increase of 18%.  Operating income for the fourth quarter of 2005
      climbed 20% to $510,000, compared to $424,000 in the prior year.


      Net income for the fourth  quarter was  $499,000,  or $0.03  earnings  per
      diluted share,  compared to $893,000, or $0.06 earnings per diluted share,
      during the same period last year.  Net income for the quarter  excluding a
      tax benefit of $79,000, increased approximately 25% to $421,000,  compared
      to fourth  quarter 2004 net income of $335,000  excluding a tax benefit of
      $558,000.


      Gil Allon, Chief Executive Officer of the Company,  commented, "Our strong
      performance in 2005 led to a record year in revenue and operating  income.
      We continue to  experience  strong sales from our line of digital  imaging
      equipment products.  In October 2005, we announced four new products,  the
      OIS  WinStation  11KTM,  OIS WinStation  XPTM Version 10.3  Software,  OIS
      WinStation ManagerTM, and OIS Ophthalmology OfficeTM Retinal Templates. In
      addition we recently  announced an important  contract with leading health
      care  provider  Henry  Ford  Health  System to upgrade  the  ophthalmology
      departments in 15 of their locations to fully integrated digital systems.


                       * * * * C O N T I N U E D* * * * *




      In 2005, we completed  our first full year of sales for the  Ophthalmology
      Office,  an  advanced  informatics  line  of  products  introduced  to the
      ophthalmology  market in mid 2004. We continue to build sales momentum and
      believe our marketing  strategy for Ophthalmology  Office remains on track
      with a strong  foundation  for future  sales.  Our plan is to leverage our
      existing  digital imaging  equipment  customers to drive strong growth for
      Ophthalmology Office in fiscal 2006."


      Ariel Shenhar, Chief Financial Officer of OIS, stated,  "Through our solid
      market  performance  we continue to strengthen  our cash  position,  which
      increased 98% to $3.9 million as of December 31, 2005, from $2 million the
      same period last year. As of December 31, 2005,  working  capital was $4.7
      million,  compared to $1.7 million a year ago. Total shareholder equity as
      of December  31,  2005 was $4.6  million  compared  to $2.4  million as of
      December 31, 2004, an increase of 93%."



      ABOUT OPHTHALMIC IMAGING SYSTEMS

      Ophthalmic Imaging Systems (www.oisi.com),  a majority-owned subsidiary of
      MediVision, is the leading provider of ophthalmic digital imaging systems.
      The Company  designs,  develops,  manufactures and markets digital imaging
      systems  and  informatics  solutions  for the eye care  market.  With over
      twenty  years  in  the  ophthalmic  imaging  business,   the  Company  has
      consistently introduced new, innovative technology.  The Company, together
      with MediVision, co-market and support their products through an extensive
      network of dealers, distributors, and direct representatives.


      Statements  in this  press  release  which  are not  historical  data  are
      forward-looking   statements   which  involve  known  and  unknown  risks,
      uncertainties, or other factors not under the Company's control, which may
      cause actual  results,  performance,  or achievements of the Company to be
      materially different from the results,  performance, or other expectations
      implied by these  forward-looking  statements.  These factors include, but
      are not limited to, those detailed in the Company's  periodic filings with
      the Securities and Exchange Commission.


                                 (TABLES FOLLOW)




                           OPHTHALMIC IMAGING SYSTEMS


                             SELECTED FINANCIAL DATA


                               STATEMENT OF INCOME



                                                                     UNAUDITED                              AUDITED
                                                               THREE MONTHS ENDED                    TWELVE MONTHS ENDED
                                                                    DECEMBER 31,                          DECEMBER 31,
                                                         -------------------------------       -------------------------------
                                                            2005               2004                  2005                2004
                                                         ------------       ------------       ------------       ------------
                                                                                                       
Sales - Total                                              $4,142,171         $3,523,202        $13,650,507        $11,293,592
Cost of sales - Total                                      $1,731,101         $1,496,663         $5,766,883         $4,793,518

                                                         ------------       ------------       ------------       ------------
Gross Profit                                               $2,411,070         $2,026,539         $7,883,624         $6,500,074

Operating Expenses:
   Sales & Marketing                                       $1,180,684           $925,861         $3,439,046         $2,907,844
   General & Administrative                                  $444,036           $409,048         $1,442,959         $1,205,765
   Research & Development                                    $276,710           $267,736         $1,112,023           $987,769
                                                         ------------       ------------       ------------       ------------
   Total Operating Expenses                                $1,901,430         $1,602,645         $5,994,028         $5,101,378

Operating Income                                             $509,640           $423,894         $1,889,596         $1,398,696
   Interest & Other Expense, Net                             ($88,877)          ($88,511)         ($187,342)         ($252,100)
                                                         ------------       ------------       ------------       ------------
Income before Taxes                                          $420,763           $335,383         $1,702,254         $1,146,596
   Income Tax Benefit (expense)                               $78,000           $558,000            $53,000           $558,000
                                                         ------------       ------------       ------------       ------------
Net Income                                                   $498,763           $893,383         $1,755,254         $1,704,596
                                                         ============       ============       ============       ============

   Basic Earnings per share                                     $0.03              $0.06              $0.12              $0.12

   Shares used in the calculation of basic earnings        15,446,211         15,033,585         15,205,689         14,771,112
   per share

   Diluted Earnings per share                                   $0.03              $0.06              $0.11              $0.11

   Shares used in the calculation of diluted               17,234,532         15,940,595         16,530,277         15,772,214
   earnings per share





                           OPHTHALMIC IMAGING SYSTEMS
                             CONDENSED BALANCE SHEET


                                           As of Dec 31,     As of Dec 31,
                                               2005              2004
                                              Actual            Actual
                                           -----------       -----------
ASSETS:

  Cash and investments                       3,940,706         1,990,310
  Accounts receivable, net                   2,841,203         1,855,009
  Receivable-Related Party                     690,756
  Inventories, net                             380,676           515,391
  Deferred Tax Asset                         1,124,000         1,029,000
  Other current assets                         300,077           189,393

                                           -----------       -----------
TOTAL CURRENT ASSETS                         9,277,418         5,579,103

  Furniture & Equipment                        107,787           150,487
  Receivable-Related Party                                     1,055,512
  Other assets                                 205,355           287,929

                                           -----------       -----------
TOTAL ASSETS                                 9,590,560         7,073,031
                                           ===========       ===========

CURRENT LIABILITIES:
  Accounts payable                             512,914           472,167
  Note Payable Short Term                      508,109           776,338
  Accrued liabilities                        3,596,102         2,588,907

                                           -----------       -----------
TOTAL CURRENT LIABILITIES                    4,617,125         3,837,412
                                           -----------       -----------

LONG TERM DEBT:
  Notes Payable, less current portion          349,237           838,362

                                           -----------       -----------
TOTAL LIABILITIES                            4,966,362         4,675,774
                                           ===========       ===========

STOCKHOLDERS' EQUITY:
  Capital stock -- Common                   14,974,007        14,502,320
  Retained earnings (deficit)              (10,349,809)      (12,105,063)

                                           -----------       -----------
TOTAL STOCKHOLDERS' EQUITY                   4,624,198         2,397,257
                                           ===========       ===========

                                           -----------       -----------
TOTAL LIABILITIES AND EQUITY                 9,590,560         7,073,031
                                           ===========       ===========


                                      # # #