EXHIBIT 4.1


                                                                   
                                                   






                                      




                             SUBSCRIPTION AGREEMENT
                              AND INVESTMENT LETTER

- ----------------
Date

To the Board of Directors
Belmac Corporation
One Urban Centre, Suite 550
4830 West Kennedy Boulevard
Tampa, Florida 33609-2517

                  Re:      Subscription to Purchase Private
                           Placement Units of Belmac Corporation
                           -------------------------------------

Gentlemen:

         This will acknowledge that the undersigned hereby agrees to irrevocably
purchase from Belmac  Corporation  (the  "Company" or  "Belmac"),  a corporation
organized under the laws of the State of Florida in February 1974,  ____________
unit(s)  (collectively  the "Units") at a price of $60,000 per Unit. The Unit(s)
to be  purchased  by the  undersigned  is (are) part of a private  placement  of
securities  (the "Private  Placement") by the Company of up to 12 Units which is
being effected on an best efforts basis by the Company. Accordingly, there is no
minimum number of Units that must be sold in order for the Private  Placement to
become effective. The Company reserves the right to sell fractions of a Unit.

         If all of the Units are sold,  the Company will receive an aggregate of
$720,000 less the expenses of this Private Placement which management  estimates
will  approximate  $100,000,  including  the fee  payable  to  Coleman & Company
Securities,  Inc. ("Coleman") described below. Coleman, a member of the New York
Stock Exchange, is acting as the placement agent for the Company in placing this
Private  Placement.  Coleman  will  receive a fee equal to 10% of the  aggregate
purchase  price of the Units  sold plus an  advance  against  future  fees in an
amount equal to 10% of the  aggregate  purchase  price of any  additional  Units
beyond the first eight which are sold.  The Private  Placement will terminate on
the  sooner  to occur of the sale of all of the  Units or  September  17,  1995,
unless  extended for an additional 15 days by the mutual  consent of the Company
and Coleman.  The undersigned  understands that the information  provided to him
with  respect to the  Company  has not been  independently  verified by Coleman.
Accordingly,  there is no  representation  by Coleman as to the  completeness or
accuracy of such information.






                                                                  Initial ____
                                                                
                               Page 1 of 18 Pages         




Subscription Agreement and Investment  Letter
for investment in Units of Belmac Corporation  dated
_________ __, ____.



         Payment  for the Units  shall be made by  check,  payable  to  Citibank
N.A.-Belmac Corporation Escrow Account, and delivered to Coleman,  together with
an executed copy of this Subscription  Agreement and Investment Letter.  Payment
may be made by wire transfer pursuant to instructions  available on request from
Coleman.

         Each  Unit  consists  of a  note  (collectively,  the  "Notes")  in the
principal amount of $60,000,  bearing interest at the annual rate of 12% payable
quarterly,  and 10,000 shares (the "Unit Shares") of the Company's  common stock
(the "Common Stock"). The Notes and Unit Shares will be immediately detachable.

         The  undersigned  understands  that the  Company  is in the  process of
effecting a one for ten reverse split of its Common Stock. Accordingly, the Unit
Shares and any shares of Common  Stock into which the Note may be  converted  as
provided  herein will be issued only upon  completion  of the reverse  split and
listing  such  shares on the  American  Stock  Exchange.  All  numbers of shares
referred to herein assume completion of the reverse split.

         The  principal  of each Note is due and  payable  on the  closing  of a
Public Offering (as defined  below).  In the event that a Public Offering is not
completed  by July 31,  1996,  the  principal  of each  Note  will be  converted
automatically  into Common Stock at a price of $3.00 per share. The Company will
pay all accrued but unpaid interest to the Note holder on the conversion date.

         The Notes will not be secured and will be  subordinated  to all "Senior
Debt"  as that  term is  defined  therein.  The  Notes  will  not be  personally
guaranteed and there will be no sinking fund,  trustee or indenture with respect
thereto.

         The  principal  of each Note  will be  immediately  convertible  at the
option of the holder  thereof  into Common Stock at the price of $3.00 per share
upon 15 days notice to the  Company.  Interest  accrued but unpaid at the time a
holder  voluntarily  converts  his  Note  will  be  forgiven.   The  undersigned
understands that if a Public Offering is not completed by July 31, 1996, he will
be required to convert the principal of his Note into Common Stock at a price of
$3.00 per share.  The  conversion  price is subject to  adjustment in accordance
with the terms of the anti-dilution provisions set forth in the Notes.

         The   undersigned   understands   that   the   Company    and   Coleman
are  contemplating  a   public  offering  (the  "Public  Offering")   subsequent
to   the   completion   of   the   Private   Placement.   Any




                                                                   Initial ____
                                                                   
                               Page 2 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


registration  statement   ("Registration   Statement")  to  be  filed  with  the
Securities and Exchange  Commission (the  "Commission")  will include provisions
for  the  registration  of the  Unit  Shares  and the  shares  of  Common  Stock
underlying the Nots (the "Underlying Shares"). The undersigned acknowledges that
no assurance can be given that the  Registration  Statement,  if filed,  will be
declared effective by the Commission or, if it is, that the Public Offering will
ever be successfully completed.  Accordingly,  he warrants and represents to the
Company that he is purchasing the Units without relying on the occurrence of the
Public Offering.

         If the  Registration  Statement  is not  filed,  or if filed and is not
declared  effective,  the  holders  of a  majority  of the Unit  Shares  and the
Underlying Shares will have the right, on one occasion only through December 31,
1997, to demand that the Company register the Unit Shares and Underlying  Shares
with the Securities and Exchange  Commission (the "Commission") and use its best
efforts to have such registration statement declared effective.

         The  undersigned is aware that the Company will use the net proceeds of
this Private Placement,  which management estimates will approximate $620,000 if
all of the Units are sold,  primarily for payment of general and  administrative
expenses and working capital.  To the extent that less than all of the Units are
sold,  less  money  will  be  available  for  these  purposes.  The  undersigned
understands  and  acknowledges  that the  Company  will be  required  to  obtain
additional financing, such as that contemplated by the Public Offering, in order
to continue to operate its business over the next 12 months.

         The undersigned  acknowledges  that the Units, and the underlying Notes
and Unit Shares (the "Underlying  Securities") he is purchasing,  as well as any
Underlying  Shares  into  which  the  Notes  may be  converted,  have  not  been
registered under the Act or qualified under applicable state securities laws and
that the transferability thereof is restricted by the registration provisions of
the  Act as  well as  such  state  laws.  Based  upon  the  representations  and
agreements  being made by him herein,  the Units and  Underlying  Securities are
being sold to him pursuant to an exemption  from such  registration  provided by
Sections  4(2)  and  4(6)  of  the  Act  and  applicable  state  securities  law
qualification  exemptions.  The undersigned further  acknowledges that the basis
for the exemption may not be available if, notwithstanding such representations,
he intends merely acquiring these securities for a fixed or determinable  period
in the future,  or for a market  rise,  or for sale if the market does not rise.
The  undersigned  represents  and  warrants  that  he does  not  have  any  such
intention.  The  undersigned  agrees  that the  documentation  representing  the
Underlying  Securities  to be  received  by him,  as  well  as the  certificates
representing   any   Underlying   Shares   into   which   the   Notes   may   be





                                                                   Initial ____
                                                                     
                               Page 3 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


converted,  will bear a legend  indicating that transfer of these  securities is
restricted  by  reason of the fact  that  they  have not been so  registered  or
qualified.

         The  undersigned   represents  that  he  is  acquiring  the  Units  and
Underlying  Securities  solely  for his own  account as  principal  and not as a
nominee or agent, for investment  purposes only and not with a view to resale or
other  distribution  or  fractionalization  thereof,  nor with the  intention of
selling,transferring  or  otherwise  disposing  of  all  or  any  part  of  such
securities  for  any  particular   event  or   circumstance,   except   selling,
transferring  or  disposing  of them upon full  compliance  with all  applicable
provisions of the Act, the Securities Exchange Act of 1934 (the "Exchange Act"),
the Rules and  Regulations  promulgated  by the Commission  thereunder,  and any
applicable state securities laws. The undersigned further understands and agrees
that the securities may be sold only if they are  subsequently  registered under
the Act and qualified  under any  applicable  state  securities  laws or, in the
opinion of the  Company's  counsel,  an  exemption  from such  registration  and
qualification  is available,  and that any routine  sales of securities  made in
reliance upon Rule 144  promulgated  by the  Commission  can be made only in the
amounts set forth in and pursuant to the other terms and  conditions,  including
applicable  holding periods,  of that Rule. He also understands  that, except as
otherwise set forth  herein,  the Company is under no obligation to register the
Units or Underlying  Securities on his behalf or to assist him in complying with
any exemption from registration under the Act.

         The undersigned  represents and warrants that he has received a copy of
the  Note,  the  Company's  Form  10-K for the year  ended  June 30,  1995,  the
Company's Proxy statement for the Company's June 9, 1995 Annual Meeting, and the
Company's 1994 Annual Report,  (collectively  the  "Information  Documents") and
that he has read and understood these documents.

         The  undersigned  also represents and warrants that he (i) has reviewed
such other  documents as he deems necessary in order for him to make an informed
investment  decision;  and (ii) is fully aware of the Company's current business
prospects and weak financial condition as set forth below and in the Information
Documents.  Except  as  may be  provided  in  this  Subscription  Agreement  and
Investment  Letter  and  in the  Information  Documents,  he  warrants  that  no
representations,  statements  or  inducements  were made to him to purchase  the
Units.

         Based on the foregoing,  the undersigned  acknowledges that he is aware
that Belmac is an international  pharmaceutical  and healthcare company based in
Tampa,  Florida,  engaged  primarily  in  the research,  development,  marketing
and  distribution  of  pharmaceutical   and   healthcare   products. 





                                                                   Initial ____
                                                       
                               Page 4 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


The Company has chemical and pharmaceutical  operations in France and Spain as a
result of its 1991 acquisition of Chimos S.A. and the  establishment of a French
pharmaceutical  subsidiary,  Laboratoires Belmac S.A. (these two French entities
have since been merged into one entity named and referred to herein as "Chimos")
and the 1992 acquisition of Rimafar S.A.  (subsequently  renamed and referred to
herein as  "Laboratorios  Belmac"),  respectively.  The Company's  operations in
France  consist of the  brokerage  of  chemicals  and the  marketing of the drug
Ceredase,  manufactured by the Boston,  Massachusetts-based Genzyme Corporation.
Ceredase is used in the  treatment  of Gaucher's  Disease.  The Company uses its
facility in Spain to manufacture,  package and distribute both its own and other
companies'  pharmaceutical  products.  The Company has expanded  its  healthcare
product  distribution  business into the United States through the establishment
of Belmac Healthcare  Corporation,  Belmac Hygiene, Inc. and Belmac Health Corp.
Belmac  Healthcare  Corporation  markets  disposable  linens to emergency health
services.  Research and development  activities are conducted both in the United
States and Europe. The undersigned is also aware of the following:

         1. HISTORY OF OPERATING  LOSSES;  ACCUMULATED  DEFICIT;  UNCERTAINTY OF
FUTURE  FINANCIAL  RESULTS.  As of March 31, 1995,  the Company had a cumulative
deficit of  approximately  $62,042,000.  The  Company has  realized  significant
losses in the past and could have quarterly and annual losses in the future. The
Company  has only  recently  begun to generate  significant  revenue and has not
generated  any  profits  from  operations.  The Company  experiences  quarter to
quarter  fluctuations in revenues and profits and/or losses, some of which could
be significant.  Consequently, the Company may continue to operate at a loss for
the foreseeable future and there can be no assurance that the Company's business
will ever operate on a profitable basis.

         2. NO ASSURANCE OF SUCCESSFUL  AND TIMELY  DEVELOPMENT OF NEW PRODUCTS.
Although the Company was founded in 1974, it has only recently begun to generate
meaningful revenue from product-related  sales. The Company has made significant
progress  toward  commercialization  of  specific  products  and  has  commenced
commercialization  of others. The Company is now generating  revenues from sales
of products of its subsidiaries  Chimos and Laboratorios  Belmac which, as noted
above,  were  acquired  by  the  Company  in  August  1991  and  February  1992,
respectively. Substantial amounts of time and financial and other resources will
be required to complete the  development  and clinical  testing of the Company's
products  currently  under  development  including  the  tablet  formulation  of
Biolid(R),  the Company's macrolide  antibiotic.  Although over the last several
months the Company has continued its existing  limited  research and development
program, due to its limited cash resources, it has suspended additional research
and  development  activities  during such period  pending  receipt of additional
financing.  There is no  assurance  that the  Company  will  receive 



                                                                   Initial ____
                                                                 
                               Page 5 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


additional   funding   necessary  to  commence  full  research  and  development
activities  or that it will  otherwise  succeed  in  developing  any  additional
products with commercially viable applications.

         Although  the Company  has a number of  products  in various  stages of
development,  including  pre-clinical  and  clinical  trials,  it  has  not  yet
substantially marketed any of these products other than Biolid(R) in France, the
marketing  of  which  has  since  been   suspended   (see  "Risks   Inherent  in
Pharmaceutical  Development;  Dependence on Regulatory  Approvals" below). There
can be no  assurance  that  the  Company  will be able to  develop  large  scale
production of any particular product for clinical trials or eventual  commercial
production.  The  marketing  of  certain  of the  Company's  products  could  be
adversely  affected by delays in developing  large-scale  production  processes,
developing or acquiring  production  facilities or obtaining regulatory approval
for such processes or facilities.

         3. ADDITIONAL FINANCING REQUIREMENTS.  Belmac's pharmaceutical products
being  developed  and which may be  developed  will  require the  investment  of
substantial additional time as well as financial and other resources in order to
become commercially successful.  Following the development period, the Company's
products will  generally be required to undergo  lengthy  governmental  approval
processes, including extensive clinical testing, followed by market development.
The Company's  operating  revenues and cash resources may not be sufficient over
the next  several  years for the  commercialization  by  itself of all  products
currently  in  development.  Consequently,  the Company  may require  additional
licenses or partners  and/or  additional  financing.  The Company  believes that
careful management of its research and development activities, together with the
net proceeds from this Offering and the proposed Public  Offering,  will provide
sufficient liquidity to enable it to conduct its existing operations through the
end of 1995. Belmac further believes,  however, that by controlling and managing
its expenses,  the funds on hand together with the proceeds of this Offering and
the proposed Public Offering, the sale or license of certain of its assets which
are no longer a part of its strategic  plan, or the entering into joint ventures
with other entities will be sufficient for it to continue its operations for the
foreseeable  future.  There can be no assurance,  however,  that the Company can
conclude such commercial  arrangements or obtain additional  capital when needed
on acceptable terms, if at all.

         4. INDEPENDENT  AUDITORS'  REPORT.  Because Belmac continues to sustain
losses,  the opinion of its  independent  auditors with respect to its financial
statements  will  include  an   explanatory  paragraph  as  to  the  uncertainty
of  the  Company's   ability   to   continue   as  a   going   concern   without


                                                                   Initial ____
                                                             
                               Page 6 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


additional  funds.  The  ability  of Belmac to  continue  as a going  concern is
dependent  upon the  successful  completion  of this Private  Placement  and the
Public Offering and/or receiving sufficient revenue from its operations.

         5.  RISKS  INHERENT  IN  PHARMACEUTICAL   DEVELOPMENT;   DEPENDENCE  ON
REGULATORY  APPROVALS.  The process of creating,  scaling-up,  manufacturing and
marketing  any new human  pharmaceutical  is inherently  risky.  There can be no
assurance that any drug under development will be safe and effective.  Moreover,
pharmaceutical  products  are  subject  to  significant  regulation.  Any  human
pharmaceutical  product  developed by the Company  would require the approval of
the Food and Drug  Administration  ("FDA")  in the  United  States  and  similar
agencies in other countries.  The process of obtaining these approvals is costly
and  time-consuming,  and there can be no assurance  that such approvals will be
granted.  In general,  only a small  percentage of new  pharmaceutical  products
achieve  commercial  success.  Such  governmental   regulation  may  prevent  or
substantially delay the marketing of the Company's products and may cause Belmac
to undertake costly  procedures with respect to its research and development and
clinical testing  operations  which may furnish a competitive  advantage to more
substantially capitalized companies which compete with the Company. In addition,
the Company is required in connection with a number of its activities, to comply
with local, state and federal regulations. Non-compliance with these regulations
could  have  a  material  adverse  effect  on the  Company  and/or  prevent  the
commercialization of the Company's products.

         In 1994 the French regulatory authority requested further documentation
regarding the chemical process/characteristics of Belmac's sachet formulation of
Biolid(R). Until this additional information has been reviewed and approved, the
regulatory  authority has requested  that marketing of the product be suspended.
Although the Company regards this  administrative  action as unwarranted in view
of the  existing  safety  and  efficacy  experience  to date in  France,  it has
determined  not  to  challenge  the  administrative  decision  in  light  of its
previously  announced  decision to develop the tablet formulation for Biolid(R).
The Company  believes  that the actions of the French  regulatory  agency should
have no bearing on the  development  of and  approval  process  for a  Biolid(R)
tablet  formulation  elsewhere,  of which  there  can be no  assurance.  Once it
receives  regulatory  clearance,  the  Company  intends  to again  evaluate  its
alternatives  regarding the sachet  formulation,  including the  possibility  of
seeking a licensee or buyer for the product's rights in France.

         6.  DEPENDENCY  ON OTHERS.  The  Company  relies on outside  sources to
supply  certain  raw  materials  such  as  erythromycin  ethyl  succinate.  The 
Company  relies  on  outside  contractors  for  manufacturing  of  its  products
in   France   and   expects   to   rely   at   least   partially   on   contract


                                                                   Initial ____
                                                                   
                               Page 7 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


manufacturing  in Spain and in other  countries.  The  Company  may also need to
utilize third parties for distribution of its products.

         7. UNCERTAINTY OF  PHARMACEUTICAL  PRICING,  PROFITABILITY  AND RELATED
MATTERS.  The levels of revenues and profitability of  pharmaceutical  companies
may be affected by the continuing efforts of governmental and third party payors
to  contain  or reduce  the costs of health  care  through  various  means.  For
example,  in certain foreign markets  pricing or  profitability  of prescription
pharmaceuticals  is subject to  government  control.  In the United States there
have been,  and the Company  expects that there will continue to be, a number of
federal and state  proposals  to implement  similar  government  control.  While
Belmac cannot predict whether any such legislative or regulatory  proposals will
be adopted,  the adoption of such proposals could have a material adverse effect
on the Company's business,  financial condition and profitability.  In addition,
in both the United States and elsewhere,  sales of prescription  pharmaceuticals
are dependent in part on the  availability of reimbursement to the consumer from
third party payors, such as government and private insurance plans.  Third party
payors are increasingly  challenging the prices charged for medical products and
services.  If the  Company  succeeds  in  bringing  one or more  products to the
market,  there can be no assurance that these  products will be considered  cost
effective  and that  reimbursement  to the consumer will be available or will be
sufficient to allow the Company to sell its products on a competitive basis.

         8.  ACCOUNTS  PAYABLE  DELINQUENCIES.   A  significant  number  of  the
Company's  accounts  payable have been or are delinquent.  As of March 31, 1995,
the Company had total  accounts  payable in the amount of  $5,681,000,  of which
approximately 5% or $300,000 was overdue.  The Company will utilize a portion of
the proceeds of this Offering to make some of these payments.

         9.  UNPREDICTABILITY  OF  PATENT  PROTECTION;  PROPRIETARY  TECHNOLOGY.
Belmac has filed numerous patent  applications  and has been granted a number of
patents.  However,  there can be no assurance that its pending applications will
be issued as patents  or that any of its issued  patents  will  afford  adequate
protection to the Company or its  licensees.  Other private and public  entities
have also filed applications for, or have been issued,  patents and are expected
to obtain  patents  and other  proprietary  rights  to  technology  which may be
harmful to the  commercialization of the Company's products.  The ultimate scope
and  validity  of  patents  which  are now owned by or may be  granted  to third
parties in the  future,  the extent to which the Company may wish or be required
to acquire  rights  under such  patents,  and the cost or  availability  of such
rights cannot be  determined  by the Company at this time.  In addition,  Belmac
also   relies  on   unpatented   proprietary   technology   in  the  development

                                                                   Initial ____
                                                        
                               Page 8 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


and commercialization of its products. There is no assurance that others may not
independently  develop the same or similar  technology  or obtain  access to the
Company's proprietary technology.

         Belmac also relies upon trade secrets,  unpatented proprietary know-how
and continuing  technological  innovations to develop its competitive  position.
All of  the  Company's  employees  with  access  to  the  Company's  proprietary
information  have entered  into  confidentiality  agreements  and have agreed to
assign the Company any  inventions  relating to the  Company's  business made by
them while in the  Company's  employ.  However,  there can be no assurance  that
others may not  acquire  or  independently  develop  similar  technology  or, if
patents in all major  countries  are not issued  with  respect to the  Company's
products,  that the Company  will be able to maintain  information  pertinent to
such research as proprietary technology or trade secrets.

         10.  TECHNOLOGICAL CHANGE AND COMPETITION.  The pharmaceutical industry
has undergone rapid and significant  technological  change.  The Company expects
the technology to continue to develop  rapidly,  and the Company's  success will
depend  significantly on its ability to maintain a competitive  position.  Rapid
technological  development  may  result  in  actual  and  proposed  products  or
processes becoming obsolete before the Company recoups a significant  portion of
related research and development and commercialization expenses.

         Belmac  competes  with other  pharmaceutical  companies,  biotechnology
firms  and  chemical  companies  which  have  substantially  greater  financial,
marketing  and human  resources  than those of the Company  (including,  in some
cases,  substantially  greater  experience in clinical  testing,  production and
marketing of pharmaceutical  products). The Company also experiences competition
in the  development  of its products and processes from  individual  scientists,
hospitals,  universities and other research institutions and, in some instances,
competes with others in acquiring technology from these sources.

         11.  ATTRACTION  AND RETENTION OF KEY PERSONNEL.  The Company  believes
that it has been successful in attracting skilled and experienced management and
scientific  personnel.  There can be no  assurance,  however,  that  Belmac will
continue to attract and retain personnel of high caliber. Since January 1994 two
individuals who have each served as chief executive  officer and a member of its
board of directors  and an  additional  member of its board have  resigned  from
their respective  positions.  The loss of key management or scientific personnel
could have an adverse  impact on the  Company.  The Company has not entered into
non  competition   agreements   with  its  key  employees   and  such  employees
would  therefore  be  able  to  leave  and  compete  with   the  Company.





                                                                   Initial ____
                                                               
                               Page 9 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


         12. RISK OF PRODUCT  LIABILITY.  The Company faces an inherent business
risk of  exposure to product  liability  claims in the event that the use of its
technology  or  prospective  products  is  alleged to have  resulted  in adverse
effects.  While it has taken,  and will  continue to take,  what it believes are
appropriate  precautions,   there  can  be  no  assurance  that  it  will  avoid
significant liability exposure.  Belmac maintains product liability insurance in
the amount of $5 million. However, there is no assurance that this coverage will
be  adequate in terms and scope to protect the Company in the event of a product
liability claim. In connection with the Company's  clinical testing  activities,
the Company may, in the ordinary  course of business,  be subject to substantial
claims by, and liability to, subjects who participate in its studies.

         13. VOLATILITY OF SHARE PRICE. The market price of the Company's shares
since  Belmac's  initial  public  offering in February  1988 has been  volatile.
Factors such as  announcements  of  technological  innovations or new commercial
products by the  Company or its  competitors,  the results of clinical  testing,
patent  or  proprietary  rights,  developments  or  other  matters  may  have  a
significant impact on the market price of the Common Stock.

         14.  POSSIBLE  DELISTING OF COMMON STOCK FROM AMERICAN STOCK  EXCHANGE.
The Company  currently  does not satisfy some of the American  Stock  Exchange's
financial  guidelines for continued listing of its Common Stock. While there can
be no assurance  that listing on the American  Stock Exchange will be continued,
management of the Company  believes that the  Company's  business  prospects are
improving and that it will be able to maintain continued listing.  If the Common
Stock were  delisted,  an investor could find it more difficult to dispose of or
to obtain accurate quotations as to the price of the Common Stock.

         15. LACK OF DIVIDENDS;  INABILITY TO FUND DIVIDEND PAYMENTS. Belmac has
not paid  dividends on its Common Stock since its  inception and does not intend
to pay any dividends on its Common Stock in the foreseeable  future. The holders
of the  Company's  outstanding  Series A Preferred  Stock have been  entitled to
receive cumulative dividends, payable annually on October 15, since 1992, out of
funds legally available  therefor at the rate of $2.25 per year on each share of
Series A  Preferred  Stock.  The Company  has not paid  dividends  to holders of
Series A Preferred  Stock due on October 15, 1994.  These  arrearages  currently
have the effect of limiting  the payment of cash  dividends to holders of Common
Stock.  There can be no assurance that cash flow from Belmac's future operations
will be sufficient to meet these obligations.



                                                                   Initial ____
                                                            
                               Page 10 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.



         16.  BROAD DISCRETION IN APPLICATION OF PROCEEDS.  Approximately all of
the  estimated  net proceeds  from this  Offering has been  allocated to working
capital.  Accordingly, the Company's management will have broad discretion as to
the application of such funds.

         17.  CERTAIN  FLORIDA  LEGISLATION.  The State of Florida  has  enacted
legislation that may deter or frustrate takeovers of Florida  corporations.  The
Florida  Control Share Act generally  provides that shares acquired in excess of
certain  specified  thresholds  will not possess any voting  rights  unless such
voting rights are approved by a majority vote of a  corporation's  disinterested
shareholders.   The  Florida  Affiliated  Transactions  Act  generally  requires
supermajority  approval  by  disinterested  shareholders  of  certain  specified
transactions  between a public  corporation  and holders of more than 10% of the
outstanding voting shares of the corporation (or their affiliates).  Florida law
also  authorizes  the Company to indemnify  the Company's  directors,  officers,
employees and agents.

         18. UNCERTAINTY OF ORPHAN DRUG DESIGNATION.  Under the Orphan Drug Act,
the FDA may  designate  a product or  products  as having  Orphan Drug status to
treat a rare disease or condition,  which is a disease or condition that affects
populations of less than 200,000 individuals in the United States or, if victims
of a disease number more than 200,000,  the sponsor establishes that it does not
realistically  anticipate  its product  sales will be  sufficient to recover its
costs.  If a product is designated an Orphan Drug,  then the sponsor is entitled
to recover its costs and receive certain incentives to undertake the development
and marketing of the product,  including  limited tax credits and  high-priority
FDA review of a New Drug  Application  ("NDA").  In  addition,  the sponsor that
obtains the first  marketing  approval for a designated  Orphan Drug for a given
indication is eligible to receive  marketing  exclusivity  for a period of seven
years. There may be multiple designations of Orphan Drug status for a given drug
and for different  indications.  However, only the sponsor of the first approved
NDA for a given drug for its use in  treating a given rare  disease  may receive
marketing exclusivity. While it may be advantageous to obtain Orphan Drug status
for  eligible  products,  there can be no  assurance  that the precise  scope of
protection that is currently afforded by Orphan Drug status will be available in
the future or that the current level of exclusivity  and tax credits will remain
in effect.  Currently,  Congress is considering legislation that would amend the
Orphan  Drug Act and may limit the scope of  marketing  exclusivity  granted  to
Orphan Drug products.  Moreover, the Orphan Drug Act tax credits expired on June
30, 1992. Although  legislation has been introduced to renew these tax benefits,
there can be no assurance that they will be renewed.



                                                                   Initial ____
                                                                       
                               Page 11 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


         The undersigned  understands that,  because of the Company's  financial
condition  and acute working  capital  problem as well as the other risk factors
referred to herein and in the  Information  Documents,  he could lose his entire
investment.

         The undersigned also understands the following:

         THE UNITS  HAVE NOT BEEN  REGISTERED  UNDER THE  SECURITIES  ACT OR ANY
STATE  SECURITIES  LAWS AND ARE BEING OFFERED AND SOLD IN RELIANCE ON EXEMPTIONS
FROM THE  REGISTRATION  REQUIREMENTS  OF THESE  LAWS.  THE  UNITS  HAVE NOT BEEN
APPROVED OR  DISAPPROVED BY THE  COMMISSION OR ANY STATE  SECURITIES  REGULATORY
AUTHORITY NOR HAS THE COMMISSION OR ANY SUCH  AUTHORITY  PASSED UPON OR ENDORSED
THE MERITS OF THE  OFFERING OR THE  ACCURACY  OR  ADEQUACY OF THIS  SUBSCRIPTION
AGREEMENT  AND  INVESTMENT   LETTER  AND/OR  THE  INFORMATION   DOCUMENTS.   ANY
REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.

         In connection with the  subscription  being made hereby the undersigned
also warrants and represents that:

                  (a) He  has   not   received  any  general   solicitation   or
advertising  regarding  the Private  Placement or been  furnished  with any oral
representation  or oral  information  in connection  with the Private  Placement
which is not set forth herein or in the Information Documents;

                  (b) He has  sufficient  knowledge and  experience of financial
and  business  matters  so that he is able to  evaluate  the merits and risks of
purchasing the Units and has determined that the Units are a suitable investment
for him;

                  (c) He has  the  means  to  provide  for  his  personal needs,
possesses the ability to bear the economic risk hereunder indefinitely,  and can
afford a complete loss of his investment;

                  (d) He has  carefully  read  and  reviewed  this  Subscription
Agreement  and  Investment  Letter,  the  form  of  Note,  and  the  Information
Documents, and has asked such questions of the Company's management and received
from them such  information  as he deems  necessary  in order for him to make an
informed decision with respect to the purchase of the Units;


                                                                   Initial ____
                                                                      
                               Page 12 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.



                  (e) He  understands  the meaning of the twelfth and thirteenth
paragraphs of this  Subscription  Agreement and  Investment  Letter and that the
Company will  prohibit the transfer of the  undersigned's  Units and  Underlying
Securities  absent  full  compliance  with the  Act,  the  Exchange  Act and all
applicable state securities laws;

                  (f) He has had substantial  experience in previous private and
public purchases of speculative  securities and is not relying on the Company or
its  affiliates  with  respect  to  economic  considerations  involved  in  this
investment; and

                  (g) He has reviewed  carefully  the  definition  of Accredited
Investor  as  set  forth  below  and  is  an  Accredited  Investor  within  that
definition.   The  particular   subparagraph  or   subparagraphs  by  which  the
undersigned qualifies as such is (are) filled in by him below.

                        DEFINITION OF ACCREDITED INVESTOR

                  The term  "accredited  investor"  is defined in Rule 501(a) of
Regulation D Promulgated under the Act as follows:

         (a)      Certain banks, savings and loan institutions,  broker-dealers,
                  investment  companies and other entities including an employee
                  benefit  plan  within the  meaning of Title I of the  Employee
                  Retirement  Income  Security  Act of 1974 with total assets in
                  excess of $5,000,000;

         (b)      Certain banks, savings and loan institutions,  broker-dealers,
                  investment companies and other entities including an  employee
                  benefit  plan  within  the meaning of Title I of the  Employee
                  Retirement  Income Security Act of 1974 with total   assets in
                  excess of $5,000,000;

         (c)      Any private business development company as defined in Section
                  202(a)(22) of the  Investment Advisers Act of 1940;

         (d)      Any  organization   described  in  Section  501(c)(3)  of  the
                  Internal  Revenue Code, not formed for the specific purpose of
                  acquiring   the  Units,   with  total   assets  in  excess  of
                  $5,000,000;



                                                                   Initial ____
                                                                
                               Page 13 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


         (e)      Any  director,  executive  officer or  general  partner of the
                  issuer  of  the  securities  being  offered  or  sold,  or any
                  director,  executive  officer or general  partner of a general
                  partner of that issuer;

         (f)      Any  natural  person  whose individual net worth, or joint net
                  worth with that person's  spouse, at the time  of his purchase
                  exceeds $1,000,000;

         (g)      Any natural  person who had an individual  income in excess of
                  $200,000  or,  with  that  person's  spouse a joint  income in
                  excess of $300,000  in each of the two most  recent  years and
                  who  reasonably  expects an income in excess of  $200,000,  or
                  $300,000 with that person's spouse, in the current year;

         (h)      Any trust with total assets in excess of $5,000,000 not formed
                  for the specific purpose of acquiring the securities  offered,
                  whose  purchase  is  directed  by a  sophisticated  person  as
                  described in Section 230.506(b)(2)(ii) of Regulation D; or

         (i)      Any  entity  in  which all of the equity owners are accredited
                  investors under any of the paragraphs above.

THE   UNDERSIGNED   SUBSCRIBER   IS  AN   ACCREDITED   INVESTOR   BY  REASON  OF
SUBPARAGRAPH(S) _____________ SET FORTH IN THE DEFINITION ABOVE.

         In connection  with the foregoing  representations  the undersigned has
appended hereto as EXHIBIT A, a Purchaser  Questionnaire  which he has completed
and executed.  He represents and warrants that the information set forth therein
as well as all other  information  which he is  furnishing  to the Company  with
respect to his  financial  condition  and  business  experience  is accurate and
complete as of the date hereof and he  covenants  that,  in the event a material
change should occur in such information, he will immediately provide the Company
with such revised or corrected information.

         All  notices,  requests,  demands and other  communications  under this
Subscription  Agreement  shall be in  writing  and  shall be deemed to have been
given only when  delivered in person or, if mailed,  when mailed by certified or
registered mail prepaid, to the parties at their respective  addresses set forth
herein,  or at such other address as may be given in writing in future by either
party to the other.



                                                                   Initial ____
                                                                 
                               Page 14 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.



         The undersigned acknowledges and agrees that:

                  (a) He has  full  power  and  authority  to  enter  into  this
Agreement which, upon his execution, will constitute a valid and legally binding
obligation by him;

                  (b) The Company  may, in its sole  discretion  (i) reject this
Subscription  Agreement  in  whole  or in part;  and  (ii)  accept  subscription
agreements other than in the order received;

                  (c) If for any reason this Private Placement does not close or
the undersigned's  subscription is not accepted by the Company,  the undersigned
shall have no claims against the Company, Coleman, or their respective officers,
directors,  employees  or  affiliates  and shall have no  interest in the Units,
Underlying Securities or the Company;

                  (d) He shall indemnify and hold harmless the Company, Coleman,
and their respective officers,  directors,  employees and affiliates against any
loss,  liability,  claim, damage or expense (including,  but not limited to, any
and all expenses  reasonably  incurred in investigating,  preparing or defending
against any  litigation  commenced or threatened or any claim) arising out of or
based  upon any false  representation  or  warranty  or breach or failure by the
undersigned  to comply with any covenant or  agreement  made by him herein or in
any other  document  provided by him to any of the foregoing in connection  with
this transaction;

                  (e) The representations, warranties and agreements made by the
undersigned set forth herein shall survive the closing of the Private Placement;

                  (f) Neither this  Subscription  Agreement  nor any  provisions
hereof shall be modified,  discharged or  terminated  except by an instrument in
writing  signed by the party  against  whom any  waiver,  change,  discharge  or
termination is sought;

                  (g)  The  laws of the  State  of New  York  shall  govern  the
interpretation and enforcement of this Subscription Agreement. In the event of a
dispute,  the  undersigned  agrees  that  any law suit  brought  to  enforce  or
interpret the provisions  hereof shall be brought in state or federal courts, as
appropriate,  in New York County, New York, and the undersigned agrees to submit
to the personal jurisdiction of such court;


                                                                   Initial ____
                                                      
                               Page 15 of 18 Pages




Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.



                  (h)    This  Subscription   Agreement   may   be  executed  in
counterparts,  each of which shall be deemed an original, but all of which shall
constitute the same instrument; and

                  (i)  This  Subscription   Agreement   constitutes  the  entire
agreement of the parties hereto,  and supersedes all prior  understandings  with
respect to the subject matter hereof.

                  The  undersigned  hereby agrees to purchase  ______ Unit(s) as
set forth in the first paragraph of this  Subscription  Agreement and Investment
Letter,  and  is  tendering  herewith  his  check  therefor  in  the  amount  of
$______________,  made  payable to  Citibank  N.A. - Belmac  Corporation  Escrow
Account.

Very truly yours,


DATE:____________________


_________________________
(Signature)

_________________________
(Please print name)

ADDRESS:    ______________________                 TELEPHONE NUMBER:___________

            ______________________                 SOCIAL SECURITY OR
                                                   IRS IDENTIFICATION
            ______________________                 NUMBER: ____________________

DATE:       ______________________







ACCEPTED:
BELMAC CORPORATION

By  _____________________

                     

                                                                   Initial ____
                                                                   
                               Page 16 of 18 Pages



Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.



                            ACKNOWLEDGMENT FORM FOR
                           INDIVIDUAL OR JOINT OWNERS


STATE OF  _____________

COUNTY OF _____________

                  I HEREBY  CERTIFY  that  _____________________________,  whose
name(s)  (is) (are) signed to the  foregoing  instrument  acknowledged  the same
before me in my aforesaid  jurisdiction  on this _____ day of  ________________,
19____

____________________  Notary Public

My Commission Expires _______________


                            ACKNOWLEDGMENT FORM FOR
                              PARTNERSHIP OR TRUST



                  I  HEREBY  CERTIFY that ____________________________, (general
partner of the  partnership)  (trustee  of the  trust)  executed  the  foregoing
instrument,  acknowledged  the  same as the act and  deed of said  (partnership)
(trust)  before  me  in  my  aforesaid   jurisdiction   on  this  _____  day  of
_____________ 19___.


____________________  Notary Public

My Commission Expires _______________


                        

                                                                   Initial ____
                                                                 
                               Page 17 of 18 Pages



Subscription Agreement and Investment Letter
for investment in Units of Belmac Corporation dated
_________ __, ____.


                      ACKNOWLEDGMENT FORM FOR CORPORATIONS


STATE OF  _____________

COUNTY OF _____________


         I HEREBY CERTIFY that _______________________, President and _________,
Secretary of the corporation that executed the foregoing instrument acknowledged
as the act and deed of said corporation  before me in my aforesaid  jurisdiction
on this ______ day of __________, 19___.



____________________  Notary Public

My Commission Expires _______________



                               Page 18 of 18 Pages