<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE AUDITED
FINANCIAL STATEMENTS OF CIPHERGEN BIOSYSTEMS, INC. AS OF DECEMBER 31, 1998 AND
1999 AND FOR THE YEARS ENDED DECEMBER 31, 1997, 1998 AND 1999 AND IS QUALIFIED
IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<CIK> 0000926617
<NAME> CIPHERGEN BIOSYSTEMS, INC.
<MULTIPLIER> 1,000
<PERIOD-TYPE> YEAR YEAR YEAR
<FISCAL-YEAR-END> DEC-31-1997 DEC-31-1998 DEC-31-1999
<PERIOD-START> JAN-01-1997 JAN-01-1998 JAN-01-1999
<PERIOD-END> DEC-31-1997 DEC-01-1998 DEC-01-1999
<CASH> 0 7,002 2,799
<SECURITIES> 0 0 0
<RECEIVABLES> 0 1,112 1,098
<ALLOWANCES> 0 (40) (100)
<INVENTORY> 0 730 722
<CURRENT-ASSETS> 0 9,035 4,841
<PP&E> 0 1,479 2,017
<DEPRECIATION> 0 (688) (1,150)
<TOTAL-ASSETS> 0 10,082 6,147
<CURRENT-LIABILITIES> 0 2,419 3,308
<BONDS> 0 0 0
<PREFERRED-MANDATORY> 0 0 0
<PREFERRED> 0 24,264 25,339
<COMMON> 0 16 16
<OTHER-SE> 0 (16,998) (23,296)
<TOTAL-LIABILITY-AND-EQUITY> 0 10,082 6,147
<SALES> 1,283 2,933 5,010
<TOTAL-REVENUES> 1,283 2,933 5,010
<CGS> 1,001 1,066 1,669
<TOTAL-COSTS> 1,001 1,066 1,669
<OTHER-EXPENSES> 6,865 10,034 10,966
<LOSS-PROVISION> 0 0 0
<INTEREST-EXPENSE> 236 488 179
<INCOME-PRETAX> (6,809) (8,310) (7,681)
<INCOME-TAX> 0 0 0
<INCOME-CONTINUING> (6,809) (8,310) (7,681)
<DISCONTINUED> 0 0 0
<EXTRAORDINARY> 0 0 0
<CHANGES> 0 0 0
<NET-INCOME> (6,809) (8,310) (7,681)
<EPS-BASIC> (1.01) (0.72) (0.52)
<EPS-DILUTED> (1.01) (0.72) (0.52)