CONSENT OF INDEPENDENT ACCOUNTANTS

We consent to the incorporation by reference in the registration statements
of Genzyme Corporation on Form S-8 (File Nos. 33-8881, 33-15616, 33-26329,
33-29918, 33-35067, 33-37236, 33-41933, 33-55656, 33-68188, 33-58359,
33-60437, 333-10003, 333-33249, 333-83677, 33-30007, 33-68208, 33-58351,
333-33265, 333-10005, 333-33251, 333-83669, 33-22464, 33-29440, 33-51416,
33-68186, 33-58353, 33-58355, 33-60435, 333-33291, 333-64095, 33-21241,
333-42371, 333-64103, 333-81275, 333-87967, 333-81277, 333-83673, 333-83681)
and on Form S-3 (file Nos. 33-61853, 333-59513, 333-68629, 33-64901,
333-31548, 333-82395, 333-34913, 333-26351, 333-87449, 333-82395) of our
reports, dated February 23, 2000 on our audits of the consolidated financial
statements and financial statement schedule of Genzyme Corporation, the
combined financial statements and financial statement schedule of Genzyme
General Division, the combined financial statements and financial statement
schedule of Genzyme Tissue Repair Division, the combined financial statements
and financial statement schedule of Genzyme Surgical Products and the
combined financial statements of Genzyme Molecular Oncology Division as of
December 31, 1999 and 1998, and for each of the three years in the period
ended December 31, 1999, which reports are included in this Annual Report on
Form 10-K.

/s/ PricewaterhouseCoopers LLP


Boston, Massachusetts
March 30, 1999