EXHIBIT 1

                                                November 1, 2000



Securities and Exchange Commission
Washington, D.C.  20549

Gentlemen:

We were previously the independent accountants for Aethlon Medical, Inc., and on
June 21, 2000 we reported on the consolidated financial statements of Aethlon
Medical, Inc. and subsidiaries as of and for the two years ended March 31, 2000.
On November 1, 2000 we informed Aethlon Medical, Inc. that we had merged with
McGladrey & Pullen, LLP and we would no longer be the independent accountants of
Aethlon Medical, Inc. We have read Aethlon Medical, Inc.'s statements included
under Item 4 of its Form 8-K and we agree with such statements.


                                                FREED MAXICK SACHS & MURPHY, PC




Buffalo, NY
November 1, 2000