EXHIBIT 23.1 Consent of PricewaterhouseCoopers LLP, Independent Accountants We hereby consent to the incorporation by reference in the Registration Statement on Form S-8 of our report dated February 22, 2000 relating to the financial statements, which appears in Triangle Pharmaceuticals, Inc.'s Annual Report on Form 10-K for the year ended December 31, 1999. /s/ PricewaterhouseCoopers LLP - - ------------------------------ PricewaterhouseCoopers LLP Raleigh, North Carolina January 30, 2001