Exhibit 16 October 5, 2001 Securities and Exchange Commission 450 Fifth Street, N.W. Washington, D.C. 20549 Commissioners: We have read the statements made by ImmunoGen, Inc. (copy attached), which we understand will be filed with the Commission pursuant to Item 4 of Form 8-K/A, as part of the Company's Form 8-K/A report dated August 31, 2001, filed October 5, 2001. We agree with the statements concerning our Firm in such Form 8-K/A. /s/ PricewaterhouseCoopers LLP