Exhibit 2.1

DATED THE                          DAY OF                                  2002
- --------------------------------------------------------------------------------


BETWEEN/

(1) THE PARTIES LISTED IN THE FIRST SCHEDULE

(2) CHARLES RIVER EUROPE GMBH

    AND

(3) CHARLES RIVER LABORATORIES INC.

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                            SHARE PURCHASE AGREEMENT
                   RE: BIOLOGICAL LABORATORIES EUROPE LIMITED
                            -------------------------

- --------------------------------------------------------------------------------

                                EUGENE F. COLLINS
                                   SOLICITORS
                                 TEMPLE CHAMBERS
                               3, BURLINGTON ROAD
                                    DUBLIN 4
                              LM/JOR - 7JUNE, 2002



                                    I N D E X



SECTION                                                                                                   PAGE
                                                                                                    
SECTION 1.00          DEFINITIONS AND INTERPRETATION------------------------------------------------------   2
SECTION 2.00          SALE OF SHARES----------------------------------------------------------------------   8
SECTION 3.00          CONSIDERATION-----------------------------------------------------------------------   9
SECTION 4.00          COMPLETION AND PRE-COMPLETION CONDITIONS--------------------------------------------  12
SECTION 5.00          WARRANTIES--------------------------------------------------------------------------  21
SECTION 6.00          RESTRICTION ON THE VENDORS----------------------------------------------------------  37
SECTION 7.00          INDEMNITIES ------------------------------------------------------------------------  40

SECTION 8.00          VENDORS WARRANTY REGARDING TITLE TO SHARES------------------------------------------  41
SECTION 9.00          MR. MORAN'S WARRANTIES--------------------------------------------------------------  41
SECTION 10.00         ANNOUNCEMENTS-----------------------------------------------------------------------  43
SECTION 11.00         FURTHER ASSURANCE AND AVAILABILITY OF INFORMATION-----------------------------------  43
SECTION 12.00         CONTINUING OBLIGATIONS AND ASSIGNMENT-----------------------------------------------  44
SECTION 13.00         COSTS-------------------------------------------------------------------------------  44
SECTION 14.00         NOTICES-----------------------------------------------------------------------------  44
SECTION 15.00         SEVERABILITY------------------------------------------------------------------------  46
SECTION 16.00         ENTIRE AGREEMENT AND VARIATION------------------------------------------------------  46
SECTION 17.00         GENERAL PROVISIONS------------------------------------------------------------------  47
SECTION 18.00         GOVERNING LAW AND JURISDICTION------------------------------------------------------  48

FIRST   SCHEDULE               VENDORS--------------------------------------------------------------------  49
SECOND  SCHEDULE               DIRECTORS AND SECRETARY----------------------------------------------------  50
THIRD   SCHEDULE               SUBSIDIARIES---------------------------------------------------------------  51
FOURTH  SCHEDULE               DEED OF INDEMNITY----------------------------------------------------------  53
FIFTH   SCHEDULE               PROPERTIES-----------------------------------------------------------------  54
SIXTH   SCHEDULE               WARRANTIES-----------------------------------------------------------------  55
SEVENTH SCHEDULE               SERVICE AGREEMENTS--------------------------------------------------------- 116
EIGHTH  SCHEDULE               IRREVOCABLE PROXY --------------------------------------------------------- 119
NINTH   SCHEDULE               ENVIRONMENTAL INDEMNITY---------------------------------------------------- 120
TENTH   SCHEDULE               PART A - MORAN PROPERTY MAP
                               PART B - SECOND MORAN PROPERTY MAP
ANNEXURE A                     MEMORANDUM AND ARTICLES OF ASSOCIATION
                               OF THE COMPANY AND THE SUBSIDIARIES

ANNEXURE B                     AUDITED (CONSOLIDATED) ACCOUNTS

ANNEXURE C                     ACCOUNTING PRINCIPLES OF BIOLOGICAL LABORATORIES EUROPE LIMITED




THIS AGREEMENT is made the     day of                       2002
BETWEEN the several persons whose names and addresses are set out in the first
column of the FIRST SCHEDULE (together called the "Vendors" which expression
shall include the legal personal representatives and successors thereof) of the
first part

AND

CHARLES RIVER EUROPE GMBH (the "Purchaser") a company incorporated under the
laws of Germany with its principal place of business at Stolzenseewag 32,
D88353, Kissleg, Germany of the second part;

AND

CHARLES RIVER LABORATORIES INC. an American company having its principal place
of business at 251, Ballardvale Street, Wilmington, MA01887, United States of
America (the "Guarantor") of the third part.

W H E R E A S:-

A.       Biological Laboratories Europe Limited (the "Company") is a limited
         company which was incorporated in Ireland on the 10th day of January,
         1994 under certificate number 211641 and at the date hereof has an
         authorised share capital of euro 1,245,079.02 divided into 775,200
         Ordinary shares of euro 1.50 each and 64,800 Cumulative Redeemable
         Preference Shares of euro 1.269738 each of which 345,400 Ordinary
         Shares of euro 1.50 each and 64,800 Cumulative Redeemable Preference
         Shares of euro 1.267938 each are issued and are fully paid. The 64,800
         Cumulative Redeemable Preference Shares of euro 1.267938 each are
         non-voting.

B.       The Vendors are together the legal and beneficial owners of the entire
         issued and allotted ordinary share capital of the Company as set out in
         Part I of the FIRST SCHEDULE such share capital being registered in the
         register of members of the Company in the manner set out in Part I of
         the FIRST SCHEDULE.

C.       The Vendors have agreed to sell and the Purchaser or its directly or
         indirectly wholly owned subsidiary has agreed to purchase the Shares
         (as herein defined) on the terms and conditions contained in this
         Agreement.

D.       The SECOND SCHEDULE contains particulars of the Directors and Secretary
         of the Company and the Subsidiaries at the date hereof.

                                      -3-


E.       The Memorandum and Articles of Association of the Company and the
         Subsidiaries as at the date hereof are in the form annexed hereto as
         ANNEXURE A and signed on behalf of the parties for the purpose of
         identification.

F.       The Company is the registered and beneficial owner of the entire issued
         share capital of those companies listed in the THIRD SCHEDULE.

G.       The Guarantor is joined as a party to this Agreement for the purposes
         of Section 5.19 and for no other reason.

NOW in consideration of the mutual covenants conditions agreements warranties
and payments hereafter set forth and provided for IT IS HEREBY COVENANTED AND
AGREED by and between the parties hereto as follows:-

                   SECTION 1 - DEFINITIONS AND INTERPRETATION

1.1.     DEFINITIONS

         In this Agreement and in the Schedules the following words and
         expressions shall unless otherwise expressly stated or unless the
         context otherwise requires have the following meanings:-

         THE "ACCOUNTS" means the audited Balance Sheet as at the Relevant Date
         and the audited profit and loss account for the year ended on the
         Relevant Date of each of the Group Companies including in the case of
         the Group the audited consolidated Balance Sheet as at the Relevant
         Date and the audited consolidated profit and loss account for the
         period ended on the Relevant Date, including in each case the
         directors' and auditors' reports thereon and any notes thereto together
         with all documents which are required by law to be attached thereto
         copies of which are attached hereto as ANNEXURE B;

         THE "ADDITIONAL CONSIDERATION" means the sum of euro 2,000,000;

         "ASSOCIATE" means any person firm or company excluding the Company:-

         (a) which is controlled by the person concerned; or

         (b) of which the person is an officer ; or

                                      -4-


         (c) who is the spouse, parent, issue, brother or sister of the person;

         THE "BALANCE SHEET" in relation to each of the Group Companies means
         its audited balance sheet as of the Relevant Date;

         "BUSINESS DAY" means any day except Saturdays and Sundays on which
         banks in the City of Dublin are open for business;

         the "COMPANY" means the company referred to in recital A hereof;

         the "COMPANY'S AUDITORS" means Russell Brennan Keane, RBK House,
         Irishtown, Athlone, Co. Westmeath;

         the "COMPLETION ACCOUNTS" means the accounts referred to in Section
         3.2(a) hereof;

         the "COMPANIES ACTS" means the Companies Acts, 1963 to 2001 together
         with all orders and regulations made thereunder;

         "COMPLETION" means completion of the sale and purchase of the Shares
         pursuant and in accordance with Section 4;

         the "CONSIDERATION" shall be the figure ascertained in accordance with
         Section 3.1;

         "CHARLES RIVER LEGAL OPINION" means a legal opinion in the Agreed Terms
         from the in-house legal counsel to Charles River Laboratories Inc. as
         to the authority and capacity of the Guarantor to enter into its
         obligations under Section 5.19 of this Agreement;

         "CHARLES RIVER GROUP" means Charles River Laboratories Inc., its
         subsidiaries and any Holding Company of any of its subsidiaries and any
         company in which any of the aforesaid directly or indirectly, holds or
         controls 50% or more of the issued voting share capital or voting stock
         or voting rights or holds or controls 50% or more of the rights to a
         return of capital or profits or controls the composition of the board
         of directors and "Member of the Charles River Group" shall be construed
         accordingly;

         "CUMULATIVE REDEEMABLE PREFERENCE SHARES" means 64,800 Cumulative
         Redeemable Preference shares in the issued Share Capital of the
         Company;

                                      -5-


         THE "DEED OF INDEMNITY" means a deed in the form set out in the FOURTH
         SCHEDULE;

         THE "DIRECTORS" means the persons listed in the SECOND SCHEDULE;

         THE "DISCLOSURE LETTER" means the letter of even date herewith from the
         Warrantors to the Purchaser disclosing information constituting
         exceptions to the Warranties;

         "ENVIRONMENTAL INDEMNITY" means the Indemnity in the form set out in
         the NINTH SCHEDULE;

         "EURO" AND "euro" means the lawful currency for the time being of
         Ireland;

         THE "GENERAL WARRANTIES" means those warranties set out in Clause 1 to
         46 inclusive of the SIXTH SCHEDULE;

         the "GROUP COMPANIES" means the Company and the Subsidiaries or where
         the context so requires any one or more thereof and "Group" shall mean
         the Company and the Subsidiaries and "Member of the Group" shall be
         construed accordingly;

         "HOLDING COMPANY" means a holding company as defined under Section 155
         of the Companies Act 1963;

         THE "INTELLECTUAL PROPERTY" means all patent, patent applications,
         trade mark, trade mark applications, trade names, designs, copyright,
         know-how, technical knowledge and information or other similar
         industrial or commercial rights used by or owned by any of the Group
         Companies in connection with any part of the business of any of the
         Group Companies anywhere in the world and whether registered or not but
         excluding for the avoidance of doubt the Ovagen Intellectual Property
         and the intellectual property the subject of the Patent Licence;

         the "MERGERS ACT" means the Mergers & Take-Overs (Control) Acts, 1978
         to 2002;

         the "MINISTER" means the Minister for Enterprise, Trade & Employment;

         "MORAN AND CAULFIELD LETTER" means a letter of even date in the Agreed
         Terms from Mr. Leonard Moran and Ms Catherine Caulfield to the
         Purchaser;

         "NET ASSETS" means the total assets of the Group less the total
         liabilities of the Group and less any provisions for liabilities and
         charges and government grants not released to the profit and loss
         account;

                                      -6-


         "NET CASH" means the cash in hand and the Company's deposits repayable
         on demand to the Company, less overdrafts;

         "OVAGEN OPTION" mean the option in the Agreed Terms concerning the
         issued share capital of Ovagen International Limited and the Ovagen
         Intellectual Property;

         "OVAGEN INTELLECTUAL PROPERTY" means technical knowhow. patents, patent
         applications, trade mark, trade mark applications, tradenames, designs,
         copyright, technical knowledge and information or other similar
         industrial or commercial rights used by or owned by Ovagen
         International Limited (or any of the people it employs or any of its
         directors or shareholders) in connection with the Ovagen Project.

         "OVAGEN PROJECT" means a project established by Ovagen International
         Limited and/or its shareholders to establishing a sustainable germ free
         chicken which is derived by surgical procedure.

         "PATENT LICENCE" means an agreement in the Agreed Terms amending the
         Patent Licence dated 11 June, 1998 between the Company, Leonard Moran,
         Catherine Caulfield and Martin Murphy;

         "PENSION ACTS" means the Pensions Act 1990 to 2002;

         THE "PROPERTIES" means the properties of the Group Companies short
         particulars of which are set out in the FIFTH SCHEDULE;

         "PURCHASER'S AUDITORS" means PricewaterhouseCoopers;

         "PURCHASER'S SOLICITORS" means Eugene F. Collins;

         "RELEVANT BUSINESS" means the business of researching and testing
         medical products, animal breeding, animal research, veterinary trials
         and testing of medical products for animal and human use and all
         business which may be carried on in connection with foregoing.

         the "RELEVANT DATE" means 31 January, 2002;

         THE "SHARES" means the entire issued and allotted ordinary share
         capital of the Company;

         the "SUBSIDIARIES" means the companies, certain details of which are
         listed in the THIRD SCHEDULE and a "Subsidiary" means a subsidiary as
         defined in Section 155 of the Companies Act, 1963;

                                      -7-


         "SDCA" means the Stamp Duties Consolidation Act, 1999;

         "TAXATION" includes (without limiting the generality of the same) all
         forms of taxation, duties, imposts, levies and rates whatsoever and
         whether of Ireland or elsewhere including (but without limitation)
         income tax, corporation tax (including any additional duty to
         corporation tax and any surcharge), corporation profits tax, advance
         corporation tax, capital gains tax, capital acquisitions tax,
         residential property tax, value added tax, customs and other import and
         export duties, excise duties, pay related social insurance (PRSI),
         social welfare and social insurance contributions, payroll taxes
         generally, rates and water rates, withholding tax, deposit interest
         retention tax, dividend withholding tax and any and all other taxes,
         levies, duties or impositions whether similar to, replaced by or
         replacing any of them or otherwise and any penalty, charge and interest
         included in or relating to any tax assessment or liability therefor and
         whether incurred as principal, agent or trustee and regardless of
         whether such taxes, penalties, charges and interest are directly or
         primarily chargeable against or attributable to any of the Group
         Companies or any other person, firm or companies and all costs,
         charges, interest, fines, penalties, surcharges and expenses in
         addition or relating thereto and the expression "tax" shall be
         construed accordingly;

         "TCA" means the Taxes Consolidation Act, 1997 (as amended);

         the "TAX WARRANTIES" means those warranties set out in Clauses 47 to
         172 inclusive of the SIXTH SCHEDULE;

         "VENDORS AUDITORS" means Russell Brennan Keane;

         "VENDORS' SOLICITORS" means Arthur Cox;

         "WARRANTIES" means the General Warranties and the Tax Warranties set
         out in Section 4.00 and the SIXTH SCHEDULE.

         "WARRANTORS" means the Vendors.

1.2      INTERPRETATION

1.2.1    Words and phrases the definition of which is contained or referred to
         in the Companies Acts shall be construed as having the meanings thereby
         attributed to them.

1.2.2    References to statutory provisions shall be construed as references to
         those provisions as respectively amended or re-enacted (whether before
         or after the date hereof) from time to time and shall include any
         provisions of which they are re-enactments (whether with or without

                                      -8-


         modification) and shall also include any subordinate legislation made
         from time to time under those provisions.

1.2.3    Reference to the singular includes reference to the plural and vice
         versa and reference to the masculine gender includes reference to the
         feminine and neuter genders and vice versa.

1.2.4    Unless the context otherwise requires, reference to any section,
         clause, sub-clause, paragraph, recital, schedule or annexure is to a
         section, clause, sub-clause, paragraph, recital, schedule or annexure
         (as the case may be) of or to this Agreement.

1.2.5    Any reference to a document as being in Agreed Terms shall mean a
         document in terms agreed between the parties thereto or their
         respective Solicitors and initialled by them for the purpose of
         identification.

1.2.6    All warranties, representations, indemnities, covenants, agreements and
         obligations given or entered into by more than one person are given or
         entered into jointly and severally.

1.2.7    All warranties, representations, indemnities, covenants, agreements and
         obligations given or entered into by any of the Vendors or the
         Warrantors being an individual shall be binding upon that Vendor or
         Warrantor and upon his or her personal representatives and estate.

1.2.8    The headings contained in this Agreement, the Schedules hereto and in
         the index to this Agreement, are inserted for convenience of reference
         only and shall not in any way form part of nor affect or be taken into
         account in the construction or interpretation of any provisions of this
         Agreement or the Schedules.

1.2.9    The Schedules to this Agreement shall form part of this Agreement and
         the expression "this Agreement" as used in any of the Schedules shall
         mean this Agreement.

1.2.10   All references to Schedules and Annexures shall be deemed to be
         references to Schedules and Annexures to this Agreement.

1.2.11   Words such as "hereunder", "hereto", hereof" and "herein" and other
         words commencing with "here" shall unless the context clearly indicates
         to the contrary refer to the whole of this Agreement and not to any
         particular section or clause thereof.

1.2.12   For the purposes of this Agreement and of the Deed of Indemnity and of
         the Disclosure Letter a matter shall be treated as being within the
         knowledge, information or belief of the Warrantors or the Vendors', if
         such matter is within the knowledge, information or belief individually
         or collectively of the Vendor's Solicitors or Vendor's Auditors and any
         statement

                                      -9-


         such as "so far as the Warrantors are aware" or "so far as the Vendors
         are aware" or "to the best of the knowledge information or belief of
         the Warrantors" or "to the best of the knowledge, information or belief
         of the Vendors" shall be construed accordingly.

1.2.14   Reference in this Agreement to writing or similar expressions include
         where the context so admits transmission by telecopier or comparable
         means of communication.

1.2.15   Reference to a document includes that document as amended or
         supplemented from time to time.

1.2.16   All reference in this Agreement to costs, charges or expenses include
         any value added tax or similar tax charged or chargeable in respect
         thereof.

1.2.17   Each party has had the opportunity to take legal advice on this
         Agreement so that no term shall be construed "contra proferentem"

1.2.18   The descriptions set out in square brackets in paragraphs 47 to 172 of
         the SIXTH SCHEDULE in relation to certain taxation provisions are for
         convenience of reference only and shall not affect or limit the
         interpretation of any provision of those paragraphs.

1.2.19   Reference to any tax in respect of income or profits or gains or
         chargeable gains earned accrued or received on or before a particular
         date or in respect of a particular period shall include any tax in
         respect of income or profits or gains deemed to have been or treated as
         earned, accrued or received at or before that date or in respect of
         that period;

1.2.20   References in the context of taxation to the result of acts, omissions
         or transactions occurring or effected prior to Completion shall include
         the combined result of two or more acts, omissions or transactions of
         which one or more shall have occurred or been effected prior to
         Completion and provided that any acts, omission or transactions which
         occur or are effected post Completion shall have occurred or been
         effected in the ordinary course of business post Completion;

                           SECTION 2 - SALE OF SHARES

2.1      Subject to the terms and conditions of this Agreement, each of the
         Vendors shall sell as legal and beneficial owner and the Purchaser
         shall purchase the Shares (either in its own name or in the name of its
         nominee) in reliance on the Warranties, the Deed of Indemnity, the
         Environmental Indemnity and the other provisions of this Agreement free
         from all liens, charges, equities and encumbrances and together with
         all rights now or hereafter attaching

                                      -10-


         thereto which shares are set out opposite the Vendors' names in the
         third column of Part I of the FIRST SCHEDULE.

2.2      The Purchaser shall not be obliged (but shall be entitled at its sole
         discretion) to complete the purchase of any of the Shares unless the
         purchase of all of the Shares is completed simultaneously.

2.3      The execution by the Vendors of this Agreement shall constitute a
         consent by each of them in relation to the sale of the Shares and each
         of the Vendors hereby irrevocably waives all rights of pre-emption (if
         any) conferred on him / her or otherwise in relation to the Shares.

                            SECTION 3 - CONSIDERATION

3.1      The Purchase Price for the Shares shall consist of , and be payable as
         follows:

         (a) The sum of euro 22,500,000 (twenty two million five hundred
             thousand euro) shall be paid on Completion in accordance with
             Section 4.8 to the Vendors' Solicitors for and on behalf of the
             Vendors; and

         (b) A further sum of not more than euro 2,500,000 (two million five
             hundred thousand euro) ("the Retention Amount") or such lesser
             amount as may be determined under Section 3.2(a) to (g) inclusive
             will be payable in accordance with the terms of Section 3.2 (a) to
             (g) inclusive; and

         (c) The Additional Consideration shall be paid in accordance with the
             terms of Section 3.3;

         Provided always that payment of any sum due hereunder to the Vendors'
         Solicitors shall be a complete discharge of the Purchaser's obligation
         to make any payment to the Vendors and payment to the Vendors'
         Solicitors shall be deemed to be a payment to the Vendors and the
         Purchaser shall have no further liability hereunder in respect thereof.
         The Vendors acknowledge and irrevocably accept these terms.

COMPLETION ACCOUNTS

3.2 (a)      As soon as reasonably practicable after Completion and in any
             event no later than 30 Business Days after Completion, the Company
             shall produce a set of completion accounts of the Company and the
             Subsidiaries consisting of profit and loss for the period from 1
             February, 2002 to Completion and a balance sheet as at Completion
             with appropriate notes thereto as at Completion (the "Completion
             Accounts") which

                                      -11-


             Completion Accounts shall state the Net Assets position and Net
             Cash position of the Company and the Subsidiaries at Completion.

         (b) Upon finalisation of the Completion Accounts (that is no later than
             30 Business Days after Completion) a copy of the final Completion
             Accounts shall be delivered by the Purchaser to Mr. Moran for and
             on behalf of the Vendors for review together with written
             confirmation of the amount of the Retention Amount (if any) due
             hereunder.

         (c) Subject to the terms of Section 3.2 (g) below in the event:-

             (i)         That the Net Assets of the Company and the Subsidiaries
                         on Completion as per the Completion Accounts is less
                         than euro 8,800,000 or the Net Cash of the Company and
                         the Subsidiaries as at Completion is less than euro
                         1,400,000 then the full amount of the Retention Amount
                         shall not be due or payable to the Vendors but the
                         Retention Amount shall be reduced by each euro that the
                         Net Cash and/or the Net Assets (as the case may be) as
                         per the Completion Accounts are less than the aforesaid
                         figures provided that if the deficit in the Net Assets
                         and / or the Net Cash is euro 2,500,000 or more then no
                         sum shall be due to the Vendors and the Retention
                         Amount shall be retained by the Purchaser; or

             (ii)        That the Net Assets of the Company and the Subsidiaries
                         on Completion as per the Completion Accounts is euro
                         8,800,000 or more AND the Net Cash of the Company and
                         the Subsidiaries as at Completion is euro 1,400,000 or
                         more then the Purchaser shall pay the full amount of
                         the Retention Amount to the Vendors' Solicitors for and
                         on behalf of the Vendors at the same time as the
                         Completion Accounts are delivered to Mr. Moran under
                         Section 3.2(b) above.

             3.2(d) (i)  If the Completion Accounts are such that the Retention
                         Amount will be reduced or that no payment will be made
                         both as provided under and pursuant to Section
                         3.2(c)(i) above then Mr. Moran may within 10 Business
                         Days of receipt of the Completion Accounts signify by
                         notice in writing ("a Dispute Notice") to the Purchaser
                         that he is not satisfied with the Completion Accounts.
                         Mr. Moran and the Purchaser shall then endeavour to
                         reach agreement upon same within a further 14 Business
                         Days of service of such Dispute Notice ("the Initial
                         Period") and upon agreement the relevant sum shall
                         subject to the terms of Section 3.2(g) below be paid to
                         the Vendors' Solicitors for and on behalf of the
                         Vendors.

                                      -12-


                    (ii)   If Mr. Moran (in accordance with the terms of 3.2d(i)
                           above) does not serve a Dispute Notice within 10
                           Business Days of receipt of the Completion Accounts
                           then, the Completion Accounts shall be deemed to be
                           accepted and the Purchaser shall subject to the terms
                           of Section 3.2 (g) below then make the relevant
                           payment under 3.2(c)(i) above if any (and as
                           calculated by the Purchaser) to the Vendors'
                           Solicitors on behalf of the Vendors and there shall
                           be no further obligation on the Purchaser to make any
                           payment in respect of the Retention Amount.

                    (iii)  If Mr. Moran has served a Dispute Notice in
                           accordance with the terms of 3.2(d)(i) above and Mr.
                           Moran and the Purchaser cannot agree the Completion
                           Accounts within the Initial Period, then the parties
                           shall refer the matter to an agreed independent
                           Chartered Accountant of no less than 10 years
                           standing (the "Expert") to determine the figures. If
                           the parties cannot agree on such person within a
                           period of 14 Business Days after the Initial Period
                           then either Mr. Moran or the Purchaser may request
                           the President of the Institute of Chartered
                           Accountants in Ireland (or in the event of him being
                           unwilling or unable to act then the next senior
                           person who is willing and able to so act) to appoint
                           such Expert to determine the issues and settle the
                           dispute. Each of Mr. Moran and the Purchaser shall be
                           entitled to make submissions to the Expert within a
                           period of 21 Business Days following his appointment.
                           The Expert shall determine the matter and shall
                           provide a copy of his determination to each of the
                           parties which determination shall be final and
                           binding save in the case of manifest error or fraud
                           but subject to the terms of Section 3.2 (g) below.
                           Pending the determination of the Expert there shall
                           be no obligation on the Purchaser to make any payment
                           under this Agreement in respect of the Retention
                           Amount and regardless of determination of the Expert
                           the Purchaser shall never be obliged to make any
                           payment exceeding the Retention Amount.

                    (iv)   Each party shall pay the Expert's costs in the
                           proportion as the Expert shall determine based on his
                           findings.

                    (v)    The Expert acts as an expert and not as an
                           arbitrator.

                                      -13-


         3.2(f)   BASIS OF PREPARATION OR COMPLETION ACCOUNTS:

                  The Completion Accounts shall be prepared on a basis
                  consistent with that adopted in preparing the annual accounts
                  of the Company for the three years ended 31 January, 2002
                  (save in the case of deferred tax whereby FRS 19 rather than
                  SSAP 15 shall be applied). The accounting policies used shall
                  be the policies as detailed in ANNEXURE C.

         3.2(g)   Notwithstanding the provisions of Section 3.2(a) to (e) above
                  inclusive the Vendors hereby agree that the Purchaser shall be
                  entitled to withhold an amount of euro 1 million from any
                  amount due to the Vendors under Section 3.2(a) to (e) above
                  inclusive and shall be entitled to retain that amount so
                  withheld for a period of 6 months from the date on which any
                  payment was due under Section 3.2(a) to (e) above inclusive.
                  Any amount so withheld may be used by the Purchaser solely for
                  the purpose of discharging any claim under the Environmental
                  Indemnity which arises after the date hereof or which arises
                  in the period of 6 months as aforesaid. In the event that any
                  claim is made under the Environmental Indemnity then the
                  Purchaser shall be entitled to use the amount so withheld to
                  discharge that claim and shall not be obliged to pay any
                  amount so used to the Vendors. In the event that after the
                  period of 6 months there has been no claim under the
                  Environmental Indemnity or some of the amount withheld has not
                  been used by the Purchaser then, the amount not used to
                  discharge a claim will be paid to the Vendors Solicitors for
                  and on behalf of the Vendors which payment (if any) shall be a
                  complete discharge of the Purchaser's obligations under
                  Section 3.2. The provisions of this Clause are without
                  prejudice to any right that the Purchaser has to pursue a
                  claim under the Environmental Indemnity.

ADDITIONAL SHARE CONSIDERATION

3.3      The Additional Consideration shall be payable by the Purchaser in the
         following amounts to two of the Vendors only being, Mr. Moran and Ms.
         Caulfield on the following dates:-

         (a) The sum of euro 333,333.33 (Three hundred and thirty three
             thousand, three hundred and thirty three euro and thirty three
             cent) shall be payable to Mr. Moran and the sum of euro
             333,333,33 (Three hundred and thirty three thousand, three
             hundred and thirty three euro and thirty three cent) shall be
             payable to Ms. Caulfield both on the first anniversary of
             Completion;

         (b) The sum of euro 333,333.33 (Three hundred and thirty three
             thousand, three hundred and thirty three euro and thirty three
             cent) shall be payable to Mr. Moran and the sum of
                                      -14-


             euro 333,333.33 (Three hundred and thirty three thousand, three
             hundred and thirty three euro and thirty three cent) shall be
             payable to Ms. Caulfield both on the second anniversary of
             Completion; and

         (c) The sum of euro 333,333.33 (Three hundred and thirty three
             thousand, three hundred and thirty three euro and thirty three
             cent) shall be payable to Mr. Moran and the sum of euro
             333,333.33 (Three hundred and thirty three thousand, three
             hundred and thirty three euro and thirty three cent) shall be
             payable to Ms. Caulfield both on the third anniversary of
             Completion.

                SECTION 4 - COMPLETION AND PRE-COMPLETION MATTERS

4.1      Subject to the provisions of this Section, Completion shall take place
         at the offices of the Purchaser's Solicitors on the date hereof.

4.2      Completion shall not take place unless and until the satisfactory
         fulfilment and/or performance (as the case may be) contemporaneously
         with, or prior to Completion, of the following matters:-

         A.  the parties shall have notified the transactions hereby provided
             for to the Minister pursuant to the Mergers Act and shall have
             responded to any queries raised by the Minister in respect thereof
             and pursuant thereto either:-

             (i)   the Minister shall have stated in writing that the Minister
                   has decided not to make an order under Section 9 of the
                   Mergers Act in relation to the sale and purchase herein; or

             (ii)  the Minister shall have stated in writing that the Minister
                   has made an order under Section 9 of the Mergers Act
                   prohibiting the sale and purchase herein except on certain
                   conditions which the Purchaser approves of in writing; or

             (iii) three months shall have elapsed from (a) the last date on
                   which all the enterprises involved in the sale and purchase
                   herein shall have notified the Minister or (b) the last date
                   on which any further information requested by the Minister
                   shall have been furnished to the Minister, whichever is the
                   later and the Minister not having made any order in relation
                   to the sale and purchase herein within that time;

         B.  Forbairt, Enterprise Ireland, Udaras Na Gaeltachta and Mayo County
             Enterprise Board having confirmed in writing to the Purchaser to
             its reasonable satisfaction and

                                      -15-


             to the Company their consent to the proposed acquisition by the
             Purchaser of the Shares and in each case that it does not propose
             to cancel, revoke or rebate any grant paid or payable to any of the
             Group Companies or terminate any lease with any of the Group
             Companies as a result of the acquisition by the Purchaser of the
             Shares and in the case of Forbairt only it confirming that the
             rights attaching to the Cumulative Redeemable Preference Shares in
             the capital of the Company are as provided for in the Agreement
             dated 30 September, 1998 between Messrs. Moran, Catherine
             Caulfield, Eugene Caulfield, Ann Chandler and Mr. Derek Tavernor;

         C.  The written consent of Ulster Bank Limited to the purchase by the
             Purchaser of the Shares having been obtained and confirmation from
             Ulster Bank Limited that its floating security over the company's
             undertaking, property and assets has not crystallised and it is not
             actually aware of any matter that might lead to such
             crystallisation;

         D.  The Purchaser shall have received all such consents and/or
             approvals of governmental and other agencies which it shall
             reasonably deem to be necessary in connection with the purchase of
             the Shares and such consents and/or approvals shall:-

             (i)   be received in terms reasonably satisfactory to the
                   Purchaser; and

             (ii)  remain in full force and effect on Completion.

         E.  No government or governmental supranational or state agency or
             regulatory body or trade union or works council or any other person
             or organisation having:-

             (i)   instituted or threatened any action, suit or investigation to
                   restrain, prohibit or otherwise significantly challenge the
                   completion by the Vendors or the Purchaser of any of the
                   transactions contemplated by this Agreement; or

             (ii)  threatened to take any action adverse to the interests of the
                   Vendors, any of the Group Companies or the Purchaser as a
                   result or in anticipation of any such transaction; or

             (iii) enacted any statute or regulation which would prohibit,
                   materially restrict or materially delay completion of any
                   such transaction.

         F.  The Vendors having procured the unconditional release without any
             continuing liability of any guarantees or indemnities given by any
             of the Group Companies for any obligations of the Vendors or any of
             them or any third parties.

                                      -16-


         G.  The Company and Mr. Moran, Ms. Caulfield and Martin Murphy having
             agreed the terms of the Patent Licence;

         H.  The Purchaser having carried out and being satisfied with the
             outcome of its due diligence, including an environmental audit of
             the Properties;

         I.  The Vendors having satisfied the Purchaser that the relevant Group
             Companies have good and marketable title to the Properties and that
             the Properties are adequately separated from adjoining Properties
             and that the relevant Group Companies have all necessary easements,
             leases and other rights in or over property necessary for the
             carrying out of the business of the relevant Group Companies and
             all requisite planning permissions and bye-law approvals.

4.3      The Purchaser shall be entitled to waive compliance with the provisions
         of Clause 4.2 in whole or in part as it sees fit save in respect of the
         provisions of sub-clauses A.

4.4      Upon Completion the Vendors shall:-

         A.  Deliver to the Purchaser for itself and, where appropriate, as
             agent for each of the Group Companies:-

             (i)   transfers of the Shares duly executed by the registered
                   holders thereof in favour of the Purchaser or as it may
                   direct together with the relative covering share certificates
                   or in the case of any lost share certificate an indemnity in
                   lieu thereof in terms satisfactory to the Purchaser or its
                   nominee;

             (ii)  any waivers, consents or other documents required to vest in
                   the Purchaser the full beneficial ownership of the Shares and
                   to enable the Purchaser to procure them to be registered in
                   the name of the Purchaser and/or its nominees;

             (iii) the resignations of the directors and the secretary of each
                   of the Group Companies, with a written acknowledgement under
                   seal from each of them in the Agreed Terms that he has no
                   claim against the relevant Group Company in respect of breach
                   of contract, compensation for loss of office, redundancy,
                   unfair or wrongful dismissal or on any other ground
                   whatsoever in respect of such resignation;

             (iv)  insofar as they are not in the custody of the Company, all
                   the financial and accounting books and records of each of the
                   Group Companies;

                                      -17-


             (v)    a letter in the Agreed Terms duly executed by the Vendors
                    confirming that all management or other agreements between
                    the Vendors and any of the Group Companies have been
                    terminated and that there are no sums due to the Vendors or
                    claims outstanding or pending under any such agreements save
                    for any sums due to the Vendors in respect of salary as a
                    result of them being employees of the Company;

             (vi)   the Deed of Indemnity duly executed by the Covenantors named
                    therein and each of the Group Companies together with the
                    Disclosure Letter duly executed by the Warrantors;

             (vii)  all the statutory books, minute books and other record books
                    (duly written up to date) of each of the Group Companies and
                    their Certificates of Incorporation and any Certificates of
                    Incorporation on Change of Name and common seals together
                    with any cancelled share certificates;

             (viii) all other documents of record and other documents and papers
                    of the Group Companies including all available documents of
                    title to the Properties and all other agreements and
                    contracts of whatsoever nature or kind in its possession or
                    under its control including (without prejudice to the
                    generality of the foregoing) the originals of the following
                    licences/certificates:-

                    (a) Current Certificate of Registration of the Properties
                        under the Cruelty to Animals Act, 1876; and

                    (b) Current Certificate of Good Laboratory Practice;

             (ix)   certificates in respect of all issued shares in the capital
                    of each of the Subsidiaries and transfers of all shares in
                    any Subsidiary held by any nominee in favour of such persons
                    as the Purchaser shall direct;

             (x)    bank statements or other suitable information showing the
                    financial position of each of the Group Companies with their
                    bankers at close of business on the Business Day immediately
                    prior to Completion;

             (xi)   service agreements between the Company and Ms. Caulfield and
                    the Company and Mr. Moran in the form set out in the SEVENTH
                    SCHEDULE DULY EXECUTED;

             (xii)  any power of attorney under which any document is executed;

                                      -18-


             (xiii)  the resignation in writing of the existing auditors of each
                     of the Group Companies acknowledging that they have no
                     claim against the particular Group Company arising from
                     their resignations and containing a statement that there
                     are no circumstances connected with their resignation which
                     they consider should be brought to the notice of the
                     members or creditors of the Group Companies (or any of
                     them);

             (xiv)   the audited accounts for the Group Companies for the year
                     ended 31 January, 2002 approved and signed by the Directors
                     and Auditors and copies of the Annual General Meeting
                     Minutes for each of the Group Companies as held together;

             (xv)    the Patent Licence duly executed by all parties thereto;

             (xvi)   the original written consent in the Agreed Terms of
                     Forbairt and any other grant bodies and Ulster Bank Limited
                     such consents being referred to in Section 4.2 B and C
                     respectively;

             (xvii)  Releases of Guarantees if any pursuant to Section 4.2F duly
                     executed;

             (xiii)  all company credit cards of the Vendors and all Company
                     cheque books will be delivered to the Purchaser;

             (xix)   the acknowledgements and assignments signed and referred to
                     in Section 4.6 C, D and E;

             (xx)    executed irrevocable proxies in accordance with Section 4.9
                     hereunder;

             (xxi)   the Ovagen Option in the Agreed Terms duly executed;

             (xxii)  the Moran and Caulfield Letter in the Agreed Terms duly
                     executed;

             (xxiii) the Environmental Indemnity in the Agreed Terms duly
                     executed; and

         B.  Procure that the following business is transacted at properly
             constituted meetings of the directors of each of the Group
             Companies (as the case may be):-

             (i)     (in the case of the Company only) the Directors will
                     approve the transfers of the Shares for registration and
                     the entry of the transferees in the register of members of
                     the Company, in each case subject only to the transfers
                     being subsequently presented duly stamped;

                                      -19-


             (ii)    (in the case of the Subsidiaries) the directors of the
                     Subsidiaries will approve the transfers referred to in
                     sub-clause (ix) of Clause 4.4A for registration subject
                     only to those transfers being subsequently presented duly
                     stamped;

             (iii)   the Deed of Indemnity and the Environmental Indemnity will
                     be approved and executed under seal by each of the Group
                     Companies;

             (iv)    any person nominated by the Purchaser for appointment as a
                     director or the secretary of any of the Group Companies
                     will be so appointed;

             (v)     the resignations referred to in Clause 4.4A(iii)
                     (Directors) and (xiii) (Auditors) shall be submitted and
                     accepted;

             (vi)    the service agreements referred to in Clause 4.4A(xi) shall
                     be approved and executed on behalf of the relevant Group
                     Company;

             (vii)   all relevant bank mandates of the Group Companies shall be
                     amended in accordance with the Purchaser's instructions;

             (viii)  the Purchaser's Auditors shall be appointed auditors;

             (ix)    The Patent Licence shall be approved and executed under
                     Seal of the Company;

4.5      The Vendors shall on Completion give to each of the Group Companies (as
         the case may be) such notice as is required by Section 53 of the
         Companies Act, 1990 in the case of those Vendors who are directors
         and/or secretary of a Group Company.

4.6      The Vendors undertake with the Purchaser that upon or before Completion
         each of the Vendors will:

         A.  repay and fulfil or procure there to be repaid and fulfilled to
             each of the Group Companies all sums and liabilities which are
             owing incurred or outstanding to each of the Group Companies at
             Completion by him or by any Associate of himself;

         B.  return to each of the Group Companies any item of its property in
             the possession or control of himself or any Associate of himself;

         C.  confirm in writing that;

                                      -20-


             (i)     neither he nor any such Associate has any claim,
                     entitlement or rights whatsoever (whether contractual,
                     tortuous, statutory or otherwise howsoever) against any of
                     the Group Companies (other than in respect of any amounts
                     due to him in respect of salary as employee of the Company)
                     or in respect of any of the Shares;

             (ii)    that none of the Group Companies is in any way obliged or
                     indebted to him or to any such Associate (other than in
                     respect of any amounts due to him in respect of salary as
                     employee of the Company); and

             (iii)   that save as specified in the confirmation in writing
                     neither he nor any such Associate owns or has any interest
                     in any item which is then or has been at any time during
                     the six months preceding Completion used in the business of
                     any of the Group Companies ;

         D.  assign and procure that such of his Associates as the Purchaser may
             specify assign to the Company or to any Subsidiary thereof (as the
             case may be) any rights in any Intellectual Property now or then
             held by him which is used in the business of any of the Group
             Companies other than the Irish Patent Number S80644 entitled Flea
             breeding apparatus and system.

         E.  acknowledge in writing and undertake that neither he nor any
             Associate of his then has, or at any time during the six months
             preceding Completion has had, any right to use or any other right
             or interest in or relating to any such Intellectual Property
             referred to in D above other than the Irish Patent Number S80644
             entitled Flea breeding apparatus and system.

         F.  procure that any guarantee, indemnity or other obligation of any
             kind incurred by any of the Group Companies to any person for the
             account of any of the Vendors or any Associate of any of the
             Vendors is effectively discharged and released to the reasonable
             satisfaction of the Purchaser and upon signature of this Agreement
             will deliver to the Purchaser written confirmation in agreed form
             confirming that any discharges and/or releases required by this
             paragraph have been delivered to the Purchaser or that there are no
             such guarantees, indemnities or other obligations in existence
             which require release under this paragraph

             and each Vendor hereby agrees to indemnify each of the Group
             Companies and the Purchaser and keep each of the Group Companies
             and the Purchaser indemnified (in respect of his not complying with
             the foregoing paragraphs 4.6A to F (inclusive))

                                      -21-


             against any loss or liability incurred by any of the Group
             Companies and/or the Purchaser which the Group Companies and or the
             Purchaser would not have incurred had the foregoing paragraphs 4.6
             A to F (inclusive) been wholly complied with in respect of that
             particular Vendor.

         PROVIDED THAT nothing in this clause or in any document entered into
         pursuant to this clause shall:-

         (i)  require the return to any of the Group Companies of any chattel
              held by any of the Vendors or any of their Associates to enable
              him more effectively to perform his duties to any of the Group
              Companies; or

         (ii) apply to any claim, entitlement, right, obligation, indebtedness
              or interest disclosed in the Disclosure Letter (including any so
              specified which relate to his employment by any of the Group
              Companies).

4.7      Following Completion and pending registration of the Purchaser or its
         nominees as the registered holder of the Shares the Vendors declare
         that so long as they remain the registered owner of any of the Shares
         they will stand and be possessed of same and the dividends and other
         distributions of profits or surplus or other assets in respect thereof
         and all rights arising out of or in connection therewith in trust for
         the Purchaser. To give full effect to the provision of this Section the
         Vendors shall on Completion give to the Purchaser an irrevocable proxy
         in the form set out in the EIGHTH SCHEDULE, to allow the Purchaser to
         exercise all rights in relation to the Shares which a registered owner
         thereof can exercise.

4.8      Provided that the Vendors shall comply with all their obligations under
         Section 4 hereof the Purchaser shall on Completion:_

         (a) Pay to the Vendors' Solicitors the sum of euro 22,500,000 (twenty
             two million five hundred thousand euros) by electronic transfer of
             funds and the Vendors hereby acknowledge and accept that payment by
             the Purchaser to the Vendors' Solicitor shall be a complete
             discharge of the Purchaser of its obligation to make such payment;
             and

         (b) Deliver the Charles River Legal Opinion.

                             SECTION 5 - WARRANTIES

5.1      The Warrantors hereby jointly and severally warrant and represent to
         and undertake with the Purchaser and its successors in title in
         relation to each of the Group Companies in the terms set out in the
         SIXTH SCHEDULE subject only to any exceptions fairly and accurately
         disclosed in

                                      -22-


         the Disclosure Letter, and in the documents annexed thereto. No
         document or matter or information shall be deemed to have been
         disclosed to the Purchaser except to the extent that it is either
         accurately and fairly set out in or (in the case of a document) annexed
         to the Disclosure Letter. The Vendors acknowledge that the Purchaser
         has entered into this Agreement on the basis of and in reliance upon
         the Warranties. The Warranties shall be separate and independent and
         shall not be limited by reference to any other paragraph of the SIXTH
         SCHEDULE or by anything in this Agreement. Liability under any Warranty
         shall not be confined to breaches discovered before Completion nor in
         any way be modified or discharged by Completion. Reference in the
         Warranties to "the Company" shall include each company in the Group.

5.2      The Warrantors jointly and severally warrant that all information
         relating to the Group Companies (or any of them) which is known to the
         Vendors or would on reasonable enquiry be known to the Vendors and as
         to the business affairs, assets and liabilities of each of the Group
         Companies has been disclosed in the Disclosure Letter to the Purchaser.

5.3      Save in the case of fraud or wilful concealment, the Vendors hereby
         irrevocably undertake (in the event of any claim being made against
         them (or any of them) in connection with the sale of the Shares to the
         Purchaser) not to make any claim against any of the Group Companies, or
         against any director or employee of any of such companies on whom they
         may have relied before agreeing to any term of this Agreement or
         authorising any statement in the Disclosure Letter, and the Vendors
         agree with the Purchaser (as trustee for the Company) to waive any
         rights the Vendors may have in respect of any misrepresentation
         inaccuracy or omission in or from any information or advice supplied or
         given by any of the Group Companies or their respective directors or
         employees for the purposes of or in connection with the giving of the
         Warranties and the preparation of the Disclosure Letter. None of the
         information supplied by any of the Group Companies or their
         professional advisers prior to the date of this Agreement to the
         Vendors or their agents, representatives or advisers in connection with
         the Warranties or the contents of the Disclosure Letter or otherwise in
         relation to the business or affairs of any of the Group Companies shall
         be deemed a representation warranty or guarantee of its accuracy by any
         of the Group Companies or any of their employees to the Vendors and
         accordingly the Vendors waive any claim against any of the Group
         Companies or their employees which they might otherwise have in respect
         of it.

5.4      Notwithstanding the provisions of Clause 5.1:-

                                      -23-


         A.  The Warrantors shall not be liable in respect of any breach of the
             Warranties if and to the extent that the loss occasioned thereby
             has been recovered under the Deed of Indemnity or the Environmental
             Indemnity;

         B.  The liability of the Warrantors pursuant to the General Warranties
             (save the Tax Warranties) shall expire on the third anniversary of
             Completion save as regards any alleged breach of any of the
             Warranties in respect of which notice in writing (containing such
             details of the event or circumstance giving rise to such claim as
             are available to the Purchaser and an estimate (if capable of
             preparation by the Purchaser) of the total amount of the
             Warrantors' liability therefor) shall have been served on the
             Warrantors (or any of them) prior to that date PROVIDED ALWAYS that
             there shall be no such time limit insofar as any claim relates to
             or is delayed as a result of fraud, wilful misconduct, dishonesty
             or wilful concealment or where any claim relates to title to the
             Shares or the right of the Vendors to sell the Shares free from all
             encumbrances of any kind

         C.  The liability of the Warrantors pursuant to the Tax Warranties
             shall expire on the seventh anniversary of Completion save as
             regards any claim for breach of any of the Tax Warranties in
             respect of which notice in writing (containing such details of the
             event or circumstance giving rise to such claim as are available to
             the Purchaser and an estimate (if capable of preparation by the
             Purchaser) of the total amount of the Warrantors' liability
             therefor) shall have been served on the Warrantors (or any of them)
             prior to that date PROVIDED ALWAYS that there shall be no such time
             limit insofar as any claim relates to or which arose as a
             consequence of or is delayed as a result of fraud, wilful
             misconduct, dishonesty or wilful concealment.

         D.  Any claim in respect of which notice shall have been given in
             accordance with sub-clause 5.4 B and/or sub-Clause 5.4 C shall, if
             it has not been previously satisfied, settled or withdrawn be
             deemed to have been irrevocably withdrawn and lapsed unless
             proceedings in respect of such claim have been issued and served on
             the Vendors (or any of them) or their process agent Messrs Arthur
             Cox, Solicitors, not later than the expiry of the period of 12
             (twelve) months from and including the date of such notice.

         E.  The Warrantors shall not be liable under the Warranties in respect
             of any claim:-

             (i)     unless the aggregate amount of all claims for which the
                     Warrantors would otherwise be liable under this Agreement
                     and the Deed of Indemnity and the

                                      -24-


                     Environmental Indemnity exceeds euro 100,000 but if
                     liability exceeds that figure then all claims including
                     claims previously notified, shall accrue against and be
                     recoverable in full from one euro upwards from the
                     Warrantors PROVIDED THAT in the case of any claim relating
                     to the Vendors' title to or the status or validity of the
                     Shares or any claim which arose as a consequence of or is
                     delayed as a result of fraud, wilful misconduct, dishonesty
                     or wilful concealment the liability of the Warrantors shall
                     be without limitation; or

             (ii)    to the extent that the aggregate amount of the liability of
                     the Warrantors for all claims made under the Warranties and
                     the Deed of Indemnity and Environmental Indemnity would
                     thereby exceed euro 27,000,000 or such lesser figure as may
                     actually have been paid hereunder by the Purchaser as a
                     result of the operation of the provisions of Section 3.2
                     but without prejudice to the Purchaser's rights to recover
                     all sums up to and including euro 27,000,000 (or such
                     lesser figure as may actually have been paid hereunder by
                     the Purchaser as a result of the operation of the
                     provisions of Section 3.2) PROVIDED ALWAYS THAT in the case
                     of any claim relating to the Vendors' title to or the
                     status and validity of the Shares or any claim which arose
                     as a consequence of or is delayed as a result of fraud,
                     wilful misconduct, dishonesty or wilful concealment the
                     liability of the Warrantors shall be without limitation; or

             (iii)   to the extent that such liability arises solely by reason
                     of an increase in the rate of Taxation after Completion; or

             (iv)    to the extent that a specific provision or reserve in
                     respect of the liability was made in the Accounts or in the
                     Completion Accounts provided that this exemption may be
                     used only once in respect of a specific provision or
                     reserve; or

             (v)     to the extent that such liability is in respect of tax and
                     which tax is attributable to income or profits of the Group
                     Companies in respect of the period between the Relevant
                     Date and Completion and for which any of the Group
                     Companies is primarily liable and which arose in the
                     ordinary course of business of the Group Companies between
                     the Relevant Date and Completion; or

                                      -25-


             (vi)    to the extent that such liability arises due to a breach of
                     any new legislation not in force at the date hereof; or

             (vii)   to the extent that and only to the extent that the
                     Purchaser or any of the Group Companies is entitled to
                     recover and has recovered any loss or damage suffered by
                     the Purchaser or any of the Group Companies arising out of
                     such claim under the terms of any insurance policy for the
                     time being in force but provided always that nothing in
                     this sub-section shall prevent the Purchaser from being
                     able to claim any amount from the Warrantors which is not
                     recoverable under such insurance policies plus any tax and
                     costs reasonably and properly incurred in such recovery;

             (viii)  to the extent that such claim would not have arisen but for
                     a voluntary transaction, act or omission effected by the
                     Purchaser or the Company at any time after Completion which
                     the Purchaser knew or ought reasonably to have known would
                     give rise to the claim other than any such transaction, act
                     or omission:

                     (a) carried out in the ordinary course of business; or

                     (b) carried out under a binding commitment (whether legally
                         binding or not) created before Completion; or

                     (c) carried out as a result of a request (not initiated by
                         or on behalf of the Purchaser) by a regulatory
                         authority (including without limitation the Revenue
                         Commissioners) to comply with any law or any statute or
                         carried out in order to comply with any law; or

                     (d) carried out with the knowledge of the Vendors (or any
                         of them);

             (ix)    to the extent that such claim would not have arisen but for
                     the winding up of, or the cessation of, or any material
                     change in the nature or conduct of, any trade carried on by
                     the Company where the Purchaser knew or ought reasonably to
                     have known such change or cessation or winding up would
                     create such liability being a winding up, cessation or
                     change occurring on or after Completion but excluding a
                     winding up, cessation or change resulting directly from a
                     claim under the Warranties or the Deed of Indemnity or the
                     Environmental Indemnity;

                                      -26-


             (x)     to the extent that any income, profits or gains (after
                     payment of any tax thereon) to which that claim is directly
                     attributable were accrued or earned or actually received by
                     the Company and are available to the Company at Completion
                     and are not provided for in the Accounts or in the
                     Completion Accounts and continue to be available to the
                     Company at the time of the claim but provided that any such
                     income profit or gains is net of any tax payable by the
                     Company or any Group Company thereon;

             (xi)    to the extent that such claim is or could be off-set,
                     reduced, or otherwise relieved by any tax relief which is
                     available to the Company at Completion and which has not
                     been previously identified in the Accounts or the
                     Completion Accounts and which has not been withdrawn or
                     clawed back and which is and will continue to be available
                     to the Company;

             (xii)   to the extent that (and only at the date when) any Taxation
                     for which a Group Company is actually assessed is actually
                     reduced or extinguished (and is not and cannot be clawed
                     back or reclaimed by any taxation authority or other
                     authority in which case no allowance or credit will be
                     given to the Warrantors under this clause or any credit
                     given to the Warrantors shall be disallowed) as a result of
                     any such claim or liability and after deducting the costs
                     and any additional Taxation incurred or suffered by a Group
                     Company as a consequence of claiming such reduction or
                     extinguishment but provided that claiming any such
                     reduction or extinguishment will not prejudice the
                     Purchaser or the Group Companies tax affairs or tax
                     planning; or

             (xiii)  to the extent that the claim is attributable (in whole or
                     in part and if in part to the extent thereof) to, or is
                     increased as a direct result of, a change made after the
                     date of Completion in the accounting policies or the length
                     of any accounting period for taxation purposes of the
                     Purchaser or the Group Company; or

             (xiv)   If and to the extent that such claim occurs or is increased
                     as a result of any change in legislation after the date of
                     this Agreement or the withdrawal after the date of this
                     Agreement of any published concession or published general
                     practice previously made by the Revenue Commissioners or
                     any other Taxation Authority (within Ireland) but for the
                     avoidance of doubt the foregoing exclusion shall not extend
                     to the Revenue Commissioners ruling of the 20 August, 1996
                     or the Company's entitlement to manufacturing relief

                                      -27-


                     prior to Completion or post Completion with retrospective
                     effect to periods prior to Completion;

             (xv)    to the extent that such liability arises by reason of the
                     voluntary withdrawal post Completion of any claim,
                     election, surrender or disclaimer made or notice given by
                     the Company prior to the date hereof where the Purchaser
                     knew or ought reasonably to have known that such withdrawal
                     of any such claim, election, surrender or disclaimer would
                     give rise to such claim;

5.5      To the extent that the same subject matter is dealt with by more than
         one of the Warranties and a payment is made by the Warrantors (or any
         of them) to the Purchaser as a result of a claim by the Purchaser based
         on any one or more of the Warranties such payment shall preclude a
         further claim by the Purchaser in respect of the same subject matter
         and the same loss or damage based on another of the Warranties.

5.6      The amount of any successful claim against the Vendors under this
         Agreement or the Deed of Indemnity or the Environmental Indemnity shall
         be deemed to constitute a reduction in the Consideration.

5.7      The rights and remedies of the Purchaser in respect of a breach of any
         of the Warranties and the Deed of Indemnity and the Environmental
         Indemnity shall not be affected:

         A.  by the sale and purchase of the Shares; or

         B.  by any event or matter whatsoever save a specific and duly
             authorised written waiver and release by the Purchaser; or

         C.  by any investigation, audit, inquiry or examination made by or on
             behalf of the Purchaser or the Guarantor at any time whether before
             or after the date of this Agreement;

         and no single or partial exercise of any right or remedy shall preclude
         any further or other exercise.

5.8      All sums payable by the Warrantors to the Purchaser under this
         Agreement shall be paid free and clear of all deductions or
         withholdings whatsoever save only as may be required by law. If any
         such deductions or withholdings are required by law the Warrantors
         shall be obliged to pay to the Purchaser such sums as will after such
         deduction or withholding has been made leave the Purchaser with the
         same amount as it would have been entitled to receive in the absence of
         any such requirement to make a deduction or withholding. In the event
         of any sum

                                      -28-


         as deducted or withheld being recovered in whole or in part by the
         Purchaser then the Purchaser shall pay the amount recovered (less any
         costs incurred in such recovery and taxation thereon) over to the
         Vendors when received up to the amount so deducted or withheld.

5.9      For the purposes of the SIXTH SCHEDULE hereof all references to the
         Company shall mean and include where the context so admits or
         requires:-

         (a) each Subsidiary; and

         (b) the Company and its Subsidiaries.

         and is without prejudice to the definition of Group Companies.

5.10     The Purchaser warrants to the Vendors that at the date hereof it is not
         actually aware of any matter giving rise to a claim under the
         Warranties, the information or details of which the Purchaser has not
         made available to the Vendors (or some of them) or their advisers or
         brought to the attention of the Vendors (or some of them) or their
         advisers.

5.11     No breach or breaches of any of the Warranties or any covenant or
         undertaking contained in this Agreement or under the Deed of Indemnity
         or the Environmental Indemnity shall give rise to any right on the part
         of the Purchaser to rescind this Agreement after Completion but this
         shall not prejudice the right of the Purchaser to claim for any loss or
         damages and shall not prejudice the Purchaser or the Group Companies
         (or any of their) rights or limit their rights under this Agreement or
         the Deed of Indemnity or the Environmental Indemnity.

5.12     Where the Purchaser or the Company has a claim against a third party
         (including without limitation any taxation authority) in relation to
         any matter which has given rise to a claim in respect of a Warranty
         under this Agreement and in respect of which the Vendors have paid and
         discharged in full their liability therefor to the Purchaser, then
         subject as hereinafter provided, the Purchaser shall use all reasonable
         endeavours to recover any amounts due from any such third party and
         shall forthwith upon such recovery reimburse the Vendors the amount so
         recovered up to the amount paid by the Vendors under this Agreement
         (less any costs incurred in such recovery and less any tax on any
         amount recovered) PROVIDED HOWEVER that the Vendors shall indemnify the
         Purchaser against all costs, expenses, legal or otherwise reasonably
         incurred by the Purchaser which shall be discharged by the Vendors on
         an ongoing basis upon demand, provided further that the Purchaser shall
         verify to the reasonable satisfaction of the Vendors any such costs and
         expenses.

                                      -29-


5.13     Nothing in this Section 5 shall derogate from the Purchaser's
         obligation to mitigate any loss which it or the Company suffers in
         consequence of a breach of the Warranties and the Purchaser covenants
         with the Vendors that it will and will procure that the Company will
         take all reasonable steps insofar as is within its power to do so to
         mitigate any loss or liability in respect of any claim under the
         Warranties.

5.14     If in respect of any claim the liability of the Purchaser or the
         Company is contingent then the Warrantors shall not be under any
         obligation to make any payment in respect thereof unless and until such
         time as the contingent liability ceases to be contingent and becomes
         actual and provided always that notwithstanding the expiration of any
         time limits in respect of making claims hereunder or issuing
         proceedings or making payments, the Vendors shall, once the contingent
         liability becomes actual be liable for such liability and to make the
         appropriate payment notwithstanding the expiration of any time limits
         hereunder provided any such claims are made with the stated time limits
         as herein set-out.

5.15     The Warrantors shall be liable to make any payment in respect of any
         claim for a breach of the warranties on the payment date, which shall
         be ascertained as follows:-

         ten Business Days after the amount of such claim shall have been agreed
         by the parties as provided hereunder or adjudged as payable by a court
         with jurisdiction to hear such dispute and from which there is no right
         of appeal for either party unless, a court orders payment at an earlier
         date.

5.16     In the event that the Warrantors at any time after the date hereof
         shall wish to take out insurance against the Warrantors' liability
         hereunder the Purchaser undertakes to provide such reasonable
         information as the prospective insurer may reasonably require before
         effecting such insurance provided that first the insurer enters into a
         confidentiality agreement on terms reasonably satisfactory to the
         Purchaser and provided that the Purchaser shall have no obligation
         under this clause if in its reasonable opinion such disclosure of
         information would or could prejudice any of the then Group Companies or
         the Purchaser in any way.

5.17     PURCHASER'S UNDERTAKINGS AND ACKNOWLEDGEMENT THE GUARANTEE

5.17.1   The Purchaser shall procure that the Vendors shall be given within
         seven days of a written request being made by the Vendors specific
         information in relation to the Company in respect of the period prior
         to Completion which is necessary to allow the Vendors file any personal
         tax returns PROVIDED ALWAYS that the Purchaser shall not be obliged to
         disclose any information which it reasonably believes is confidential
         or the disclosure of which could be harmful or detrimental to any of
         the Group Companies.

                                      -30-


5.17.2   The Purchaser acknowledges and agrees that the Vendors make no warranty
         to it save only as and to the extent expressly set out in the
         Warranties in the SIXTH SCHEDULE to this Agreement and save for any
         representations made by the Vendors (or any of them) in any documents
         to be delivered on Completion or to be delivered post Completion
         arising out of this transaction.

5.18     The Purchaser warrants and undertakes that:-

         (a) it has the requisite powers and authorities to enter into and
             perform its obligations under this Agreement;

         (b) this Agreement constitutes valid and binding obligations of the
             Purchaser in accordance with its terms;

         (c) the execution and delivery of, and the performance by the Purchaser
             of its obligations under this Agreement will not:

             (i)     result in a material breach of, or constitute a material
                     default under, any material agreement to which the
                     Purchaser is a party or by which it is bound; or

             (ii)    result in a material breach of any order, judgment or
                     decree of any court or governmental agency to which the
                     Purchaser is a party or by which it is bound; or

             (iii)   require the Purchaser to obtain any consent or approval of,
                     or give any notice to or make any registration with any
                     governmental or other authority which has not been obtained
                     or made prior to Completion on an unconditional and
                     irrevocable basis (save for any legal or regulatory
                     entitlement to revoke the same other than for fraudulent
                     misrepresentation or misstatement by or on behalf of the
                     Purchaser);

         (d) it is acting as principal and not as agent or broker for any other
             person and, save as previously disclosed in writing to the Vendors,
             immediately following its purchase of the Shares, at Completion no
             person other than the Purchaser is legally or beneficially
             interested in the Shares;

5.19     GUARANTEE

         5.19.1   The Guarantor hereby guarantees the due, complete and punctual
                  performance by the Purchaser of its obligations under and
                  pursuant to Section 3.1(b) and 3.1 (c) only of this Agreement
                  subject always to the terms of Moran and Caulfield Letter
                  prevailing

                                      -31-


                  in respect of the Purchaser's obligations under Section 3.1(c)
                  and 3.3 of this Agreement (the "Guaranteed Obligations").

         5.19.2   If the Purchaser shall default in the performance of any of
                  the Guaranteed Obligations then the Guarantor shall, subject
                  to Section 5.19.6 herein, upon a written demand being made on
                  the Guarantor discharge forthwith such of the Guaranteed
                  Obligations as shall not have been but should have been
                  performed or discharged at the time the written demand is made
                  upon the Guarantor.

         5.19.3   The Guarantor's Obligations under Section 5.19.1 are those of
                  a mere surety.

         5.19.4   The Guarantor's liability under Section 5.19.1 shall not be
                  discharged, released, diminished, impaired or otherwise
                  affected by:

                  (a) the winding-up, dissolution, examination or
                      re-organisation of the Purchaser;

                  (b) any time, waiver or other indulgence whatsoever being
                      granted or agreed to be granted to the Purchaser or the
                      Guarantor or any other person in respect of all or any of
                      the Guaranteed Obligations.

         5.19.5   The Guarantor represents and warrants to the Vendors that:-

                  (a) the Guarantor has the necessary power and authority to
                      enter into and deliver this Guarantee and to perform the
                      Guarantor's obligations hereunder and that all necessary
                      actions to authorise the execution, delivery and
                      performance of this Guarantee and to observe and perform
                      the Guarantor's obligations under this Guarantee have been
                      taken;

                  (b) this Guarantee constitutes legal, valid and binding
                      obligations of the Guarantor;

                  (c) the execution and delivery by the Guarantor of this
                      Guarantee and the performance and observance by the
                      Guarantor of the Guarantor's obligations hereunder do not
                      and will not violate or result in a breach of, or exceed
                      any power granted to the Guarantor under:-

                      (i)   the Guarantor's memorandum and articles of
                            association or other equivalent constitutional
                            documents

                      (ii)  any law, rule or regulation to or by which the
                            Guarantor is subject or bound;

                                      -32-


                      (iii) any judgement, order, injunction, determination,
                            award or ruling of any court or arbitrator or any
                            judicial, administrative or governmental authority
                            to or by which the Guarantor is subject or bound;

5.19.6   The Vendors shall not be entitled to enforce this Guarantee without
         first making a written demand upon the Purchaser.

                     SECTION 6 - RESTRICTION ON THE VENDORS

6.1      For the purpose of assuring to the Purchaser the full benefit of the
         businesses and goodwill of each of the Group Companies each of the
         Vendors undertakes with the Purchaser and its successors in title in
         relation to the Shares for itself and as trustee for the Company and
         with each of the Group Companies that:-

         A.  for the period of two years from the date of Completion each Vendor
             will not within Ireland either on its own behalf or in conjunction
             with or on behalf of any person, firm or company carry on or be
             engaged concerned or interested either directly or indirectly in
             carrying on the Relevant Business (other than by way of bona fide
             investments or holding of shares not exceeding 5 per cent in
             nominal value of any class or share capital of a company whose
             share or loan capital is quoted or listed or regularly dealt in a
             recognised Stock Exchange) other than as an employee of any of the
             Group Companies;

         B.  for the period of two years from the date of Completion each Vendor
             will not either on its own account or in conjunction with or on
             behalf of any other person, firm or company solicit or entice away
             from any of the Group Companies any officer or manager or employee
             whether or not such person would commit a breach of his contract of
             employment by reason of leaving service provided that this clause
             6.1B shall not be construed so as to prevent or restrict the
             Vendors (or any of them) from employing any such person who
             approaches any of the Vendors or initiates a request to any of the
             Vendors for employment without direct or indirect solicitation on
             the Vendor's part or so as to prevent or restrict the Vendors (or
             any of them) from soliciting or initiating an offer of employment
             to any such person whose employment with any of the Group Companies
             has been terminated by the action of a Group Company or whose
             employment will terminate on the expiration of any notice period in
             relation to which notice of termination had been served by a Group
             Company at such time or from employing any person who applies to
             the Vendors (or any one of them) for employment in response to a
             public advertisement offering employment;

                                      -33-


         C.  for the period of two years from the date of Completion either on
             its own account or in conjunction with or on behalf of any other
             person solicit the custom of any customer of any of the Group
             Companies who is a customer of the Group Companies at Completion or
             use the Vendors' information of or influence over any such customer
             or any person firm or company known to it as contracting with or
             having dealings with any of the Group Companies to or for its own
             benefit or that of any other person firm or company in competition
             with any of the Group Companies;

         D.  the Vendors shall not be involved either directly or indirectly
             with any company or business which has in its name, or part of its
             name, regardless of the language used, the word "Biological
             Laboratories" or "Entomology" or "Saotharlanna Bitheolaiocha
             Idirnaisiunta Teoranta" or any variation, derivative or
             abbreviation thereof or any similar name in such a form or style as
             would tend to cause confusion of identity with any Group Companies
             in the minds of the public;

         E.  the Vendors will not indicate in any manner whatsoever, in any
             trade, business or operation any past association or relationship
             with any of the Group Companies; and

         F.  each Vendor shall procure that no company owned or controlled by
             such Vendor or any one or more of them (and insofar as such Vendor
             is able to ensure the same none of its subsidiaries or associated
             companies) shall act in such a way as would be a contravention of
             the obligations contained in this paragraph.

         PROVIDED ALWAYS and for the avoidance of doubt the provisions of
         Sections 6.1A and B shall not prevent certain of the Vendors from
         continuing their involvement in the development of the Ovagen
         Intellectual Property or receiving income pursuant to the Patent
         Licence.

6.2      Each Vendor agrees to keep all confidential information of the Group
         Companies confidential including without prejudice any of the trade
         secrets, secret or confidential operations, processes or dealings or
         any other confidential information concerning any of the Group
         Companies or any confidential information relating to client or
         customers of the Group Companies involving but not limited to customer
         lists and names, sales targets and statistics, market and share
         statistics, survey and reports and pricing information relating to
         sales and purchases by any Group Company until such time as the same
         shall fall into the public domain otherwise than by reason of a breach
         of this undertaking;

6.3      The restrictions contained in Clause 6.1 and 6.2 are considered
         reasonable by the parties and no greater than is necessary for the
         protection of the goodwill of the business and the value of

                                      -34-





         the shareholdings in the Company but in the event that any such
         restriction or any part thereof shall be found to be void but would be
         valid if some part thereof were deleted or the period of application
         reduced, such restriction shall apply with such modification as may be
         necessary to make it valid and effective.

6.4      The Vendors hereby declare that the benefit of each of the above
         agreements and obligations on their part shall be deemed to be separate
         and severable and enforceable by the Purchaser accordingly.

6.5      The Vendors acknowledge that the remedy at law for any breach, or
         threatened breach, of any of the restrictions contained in Section 6 of
         this Agreement will be inadequate and, accordingly, the Vendors
         covenant and agree that the Purchaser shall, in addition to any other
         rights or remedies which the Purchaser may have, be entitled to such
         equitable and injunctive relief as may be available from any court of
         competent jurisdiction to restrain the Vendors (or any of them) from
         any breach of such clause and such equitable and injunctive relief may
         be granted without the necessity of proving actual damages

         Such right to obtain equitable and injunctive relief may be exercised,
         at the option of the Purchaser concurrently with, prior to, after or in
         lieu of, the exercise of any other rights or remedies which the
         Purchaser may have as a result of any such breach or threatened breach.

                             SECTION 7 - INDEMNITIES

7.1      The Warrantors hereby jointly and severally indemnify and agree to keep
         indemnified the Purchaser and the Group Companies on demand against all
         costs, claims, damages, losses, liabilities of any kind whatsoever and
         expenses which they or any of them may incur out of or in connection
         with any transaction, sale, contract agreement or disposal or
         acquisition of any kind having been entered into by any of the Group
         Companies with Biological Laboratories (Ballina) Limited, Company
         Number 52235 ("Ballina") and/or Biological Laboratories Limited,
         Company Number 109325 and/or Seragon Limited, Company Number 107290
         and/or as a result of any of the Group Companies having as directors or
         shareholders individuals who were directors or shareholders of Ballina
         and/or Biological Laboratories Limited and/or Seragon Limited and/or as
         a result of any of the directors or shareholders of any of the Group
         Companies being connected in any way to Ballina and/or Biological
         Laboratories Limited and/or Seragon Limited.

7.2      The Warrantors shall not be liable under the Indemnities in Section 7.1
         to the extent that the aggregate amount of the liability of the
         Warrantors for all claims made under the Indemnities in Section 7.1,
         the Warranties and the Deed of Indemnity and the Environmental
         Indemnity

                                      -35-


         would thereby exceed euro 27,000,000 or such lesser figure as may
         actually have been paid hereunder by the Purchaser as a result of the
         operation of the provisions of Section 3.2 but without prejudice to the
         Purchaser's rights to recover all sums up to and including euro
         27,000,000 (or such lesser figure as may actually have been paid
         hereunder by the Purchaser as a result of the operation of the
         provisions of Section 3.2) PROVIDED ALWAYS that in the case of any
         claim relating to the Vendors' title to or the status and validity of
         the Shares or any claim which arose as a consequence of or is delayed
         as a result of fraud, wilful misconduct, dishonesty or wilful
         concealment of the liability of the Warrantors shall be without
         limitation.

             SECTION 8 - VENDORS' WARRANTY REGARDING TITLE TO SHARES

8.1      The Vendors hereby jointly and severally warrant that they are the
         registered and beneficial owners of the entire issued and allotted
         ordinary and voting share capital of the Company in the amounts
         specified in the FIRST SCHEDULE hereto and the Shares are fully paid up
         and each of the Vendors have the right and authority to sell and
         transfer the full legal and beneficial ownership thereof to the
         Purchaser on the terms set out in the Agreement and free from any
         charge, lien or encumbrance of any kind and without the consent of any
         third party and no party has any right or interest of any kind in the
         Shares.

                        SECTION 9 - MR. MORAN'S WARRANTY

9.1      Mr. Moran hereby undertakes with and warrants to the Purchaser that the
         Company has an option (the "Option") to purchase from Mr. Moran the
         property specified in the map attached to Part A of the TENTH SCHEDULE
         hereto (the "Moran Property") at a price of no more than euro 152,369
         and that such Option is legal valid and enforceable against Mr. Moran
         by the Company and can be exercised at any time in the next 10 years by
         the Company.

9.2      RIGHT OF FIRST REFUSAL

         9.2.1    Mr. Moran is the absolute owner of the unencumbered freehold
                  interest in the property specified in the map attached to Part
                  B of the TENTH SCHEDULE ("the Second Moran Property"). Mr.
                  Moran hereby agrees that if he wishes at any time after the
                  date hereof to sell or otherwise dispose of or transfer title
                  to the Second Moran Property he shall not do so without first
                  offering the Second Moran Property to the Purchaser so that
                  the Purchaser has a right of first refusal over the said
                  property.

         9.2.2    The price at which Mr. Moran shall offer the Second Moran
                  Property for sale to the Purchaser shall be at "fair market
                  value" as agreed between the Purchaser and Mr.

                                      -36-


                  Moran or if they fail to agree for 7 Business Days such fair
                  market value as assessed by an independent auctioneer agreed
                  to by the Purchaser and Mr. Moran or in the event of a failure
                  to agree on the identity of such independent auctioneer within
                  a further 10 Business Days then such independent auctioneer
                  (the "Independent Auctioneer") as appointed by the President
                  of the Institute of Auctioneers in Ireland (or in the event of
                  him being unwilling or unable to do so the next senior person
                  who is so willing to do so). The determination by the
                  Independent Auctioneer shall be final and binding save in the
                  case of manifest error. If the Purchaser on determination of
                  the Fair Market Value by the Independent Auctioneer does not
                  wish to purchase the Second Moran Property then the Purchaser
                  shall not be obliged to so purchase. If Mr. Moran on
                  determination of the fair market value by the Independent
                  Auctioneer does not wish to sell the second Moran Property
                  then Mr. Moran shall not be obliged to so sell in such
                  circumstances but he shall not be entitled to sell the Moran
                  Property to any one else without first offering it to the
                  Purchaser on the same terms (including price) as he would
                  offer such property to such other person.

         9.2.4    Any sale of the Second Moran Property shall be subject to the
                  then current Law Society Standard Conditions of Sale and based
                  upon the then current conveyancing practice with regard to
                  purchase and sale of land.

                           SECTION 10 - ANNOUNCEMENTS

10.1     No announcement or information concerning this sale and purchase, the
         contents of or existence of this Agreement, the negotiations leading
         thereto or the circumstances in respect thereof or any ancillary matter
         shall be made or released before or after Completion to the public or
         to the press (international, national, provincial, local or trade) or
         the suppliers, customers or employees of any of the Group Companies by
         any of the parties hereto without the prior written consent of the
         other parties (not to be unreasonably withheld or delayed) PROVIDED
         that nothing shall restrict the making by the Purchaser of any
         statement or disclosure or announcement which it may be required by law
         or called for by the requirements of any recognised Stock Exchange or
         prevent the Purchaser from providing any information necessary to any
         tax authority in relation to the Purchaser's tax affairs and nothing
         shall restrict the Vendors from providing any information necessary to
         any tax authority in relation to a Vendor's tax affairs.

                                      -37-


         SECTION 11 - FURTHER ASSURANCE AND AVAILABILITY OF INFORMATION

11.1     The Vendors shall (and shall procure insofar as it lies within their
         powers of procurement that any other necessary parties shall) perform
         such acts (other than stamping) and execute such documents as may be
         reasonably required on or after Completion by the Purchaser for
         securing to or vesting in the Purchaser (including its nominee or
         nominees) the legal and beneficial ownership of the Shares in
         accordance with the terms and conditions of this Agreement and assuring
         to the Purchaser the rights hereby granted and shall procure the
         convening of all such meetings (insofar as they can) and the giving or
         passing of all such waivers (including pre-emption waivers) PROVIDED
         that where any cost or expense is reasonably incurred in the completion
         of such deeds and documents the costs and expenses shall (unless the
         document was one which should have been delivered under this Agreement
         then the party who did not deliver the document shall bear the costs of
         delivering the document) be borne by the party requesting the execution
         of same.

11.2     The Vendors shall cause to be made available to the Purchaser all
         information in their possession or under their control which the
         Purchaser may from time to time reasonably require (before or after
         Completion) relating to the business and affairs of any of the Group
         Companies and shall permit the Purchaser to have access to documents
         containing such information and to take copies thereof.

               SECTION 12 - CONTINUING OBLIGATIONS AND ASSIGNMENT

12.1     Each of the obligations, Warranties, indemnities and undertakings given
         by the Vendors and the Warrantors pursuant to this Agreement ("the
         Obligations"), excluding any obligation fully performed at Completion,
         shall continue in full force and effect notwithstanding Completion
         taking place and notwithstanding any such sale or transfer as is
         referred to in Clause 12.2.

12.2     If the Shares shall be sold, transferred or charged at any time to any
         Member of the Charles River Group the benefit of each of the
         Obligations shall be capable of assignment to such Member of the
         Charles River Group.

                               SECTION 13 - COSTS

13.1     Each party to this Agreement shall pay its own costs, charges and
         expenses incurred in the preparation, negotiation, completion and
         implementation of this Agreement (and the documents referred to herein)
         save that the Purchaser shall pay any stamp duty payable in connection
         with the transfer of the Shares.

                                      -38-


                              SECTION 14 - NOTICES

14.1     Any notice or other communication to be given or served under this
         Agreement shall be in writing, addressed to the relevant party and
         expressed to be a notice or communication under this Agreement and may
         be delivered by hand or sent by pre-paid ordinary post or fax;

         in the case of the Vendors (or any of them) addressed to Ms. Caulfield
         or to Mr. Moran on behalf of the Vendors as follows:-

         Address:   In the case of Ms Caulfield, 10 Gorse Grove, Foxford,
                    Co. Mayo

         Attention: Ms. Catherine Caulfield

         Address:   In the case of Mr. Moran at 4 Childers Heights, Ballina,
                    Co. Mayo

         Attention: Mr. Leonard Moran.

         Fax No for both: 09622517

         or to such other addresses or fax number as the addressee may have
         previously substituted by notice.

         and in respect of the Purchaser as follows:-

         The Purchaser: Charles River Laboratories, Inc.

         Address: 251 Ballardvale Street, Wilmington MA 01887

         Attention: General Counsel

         Fax No:    001 978 988 5665

         or to such other address or fax number as the addressee may have
         previously substituted by notice.

14.2     Any such notice or other communication will be deemed to have been duly
         served or given:

         (a) in the case of delivery, at the time of delivery;

         (b) in the case of posting 48 hours after posting (and proof that the
             envelope containing the notice or communication was properly
             addressed, prepaid and posted will be sufficient evidence that the
             notice or other communication has been duly served or given); or

                                      -39-


         (c) in the case of fax, upon transmission, subject to the correct code
             or fax number being received on the transmission report;

         provided however that if a notice is not given or served during usual
         business hours on a Business Day it will be deemed to be given or
         served on the next following Business Day.

14.3     A party giving or serving a notice or other communication hereunder by
         fax shall also give or serve a copy thereof by post but without
         prejudice to the validity and effectiveness of the service by fax.

14.4     Without prejudice to any other mode or service:

         (a) The Vendors irrevocably appoint Arthur Cox Solicitors as agent for
             service of any process or any proceedings before the courts of
             Ireland in connection with this Agreement or the Deed of Indemnity
             or the Environmental Indemnity or any documents referred to herein
             and agree to maintain Arthur Cox Solicitors as their process agent
             in Ireland during the term of this Agreement and thereafter during
             such period as any action may be taken thereunder; and

         (b) each party agrees that failure by Arthur Cox, Solicitors to notify
             it of the process or proceedings will not invalidate the
             proceedings concerned.

14.5     The Vendors hereby irrevocably appoint Mr. Moran and Ms. Caulfield to
         accept service of any letters, notices or other communication on their
         behalf (other than proceedings as referred to in Section 14.4 above)
         and to negotiate, deal with and settle any claim arising hereunder on
         behalf of the Vendors or any of them including any settlement of or
         negotiation of proceedings as referred to in 14.4 and the Vendors shall
         not be entitled to so change the aforesaid nominees without the prior
         written consent of the Purchaser and then provided all of the Vendors
         agree to make the change so that there is never more than two nominees
         of the Vendors under this Section 14. The Purchaser agrees that where
         possible it will in serving any communication (other than proceedings
         served under 14.4) on the nominees under this Section 14 also send a
         copy to the Vendor or Vendors as the case may be at their address in
         the FIRST SCHEDULE provided however that failure to so send a copy or
         any communication to the Vendor or Vendors shall not affect in any way
         service of the communication under this Section and the Vendors shall
         be deemed to have received the communication once served on any of the
         nominees in this Section 14 or any replacement nominees.

                                      -40-


                            SECTION 15 - SEVERABILITY

15.1     If any of the provisions of this Agreement or any part thereof (or of
         any of the documents referred to herein) is found by a court or other
         competent authority to be void or unenforceable for any other reason
         whatsoever, such provision or part shall be deemed to be deleted from
         this Agreement and the remaining provisions of this Agreement shall
         continue in full force and effect. Notwithstanding the foregoing the
         parties shall thereupon negotiate in good faith in order to agree the
         terms of a mutually satisfactory provision to be substituted for the
         provision so found to be void or unenforceable.

                   SECTION 16 - ENTIRE AGREEMENT AND VARIATION

16.1     This Agreement (together with the documents referred to herein and
         annexed hereto) constitutes the entire agreement between the parties in
         relation to the transactions referred to herein or therein and
         supersedes any previous agreement between the parties in relation to
         such transactions. This Agreement replaces any previous agreement,
         understanding or arrangement in the matter between the parties
         including without limitation the non binding letter of proposal dated
         16 March, 2002 which shall by mutual consent cease to have effect upon
         the signing hereof and all rights and obligations thereunder (whether
         accrued, accruing or contingent) shall terminate.

16.2     No variation of any of the terms of this Agreement (or of any other
         documents referred to herein) shall be effective unless it is in
         writing and signed by or on behalf of each of the parties hereto or
         thereto. The expression "variation" shall include any variation,
         supplement, deletion or replacement however effected.

                         SECTION 17 - GENERAL PROVISIONS

17.1     The provisions of this Agreement, insofar as the same shall not have
         been performed at Completion, shall remain in full force and effect
         notwithstanding Completion. Neither the termination nor the rescission
         of this Agreement shall affect or prejudice any provision hereof
         expressed to survive or operate in the event of the termination or
         rescission of this Agreement.

17.2     Any right of rescission or termination conferred upon the Purchaser
         under this Agreement shall be in addition to and without prejudice to
         all other rights and remedies available to it by reason of any breach
         of any provisions of this Agreement (including the Warranties) and no
         delay or omission of the Purchaser in exercising any right, power or
         privilege hereunder shall operate to impair such right, power or
         privilege or be construed as a waiver hereof and no single or partial
         exercise or non-exercise of any right, power or privilege shall in any

                                      -41-


         circumstances preclude any other or further exercise thereof or the
         exercise of any other right, power or privilege.

17.3     Any liability to the Purchaser under the provisions of this Agreement
         may be in whole or in part released, varied, compounded or compromised
         by the Purchaser in its absolute discretion as regards any of the
         Vendors or Warrantors or other party under such liability without in
         any way prejudicing or affecting its rights against any other party
         under the same or a like liability whether joint or several or
         otherwise. A waiver by the Purchaser of any breach by any party hereto
         of any of the terms provisions or conditions of this Agreement or the
         acquiescence of the Purchaser in any act (whether of commission or
         omission) which but for such acquiescence would be a breach as
         aforesaid shall not constitute a general waiver of such term, provision
         or condition or of any subsequent act contrary thereto.

17.4     This Agreement may be executed in any number of counterparts and by the
         different parties hereto on separate counterparts each of which when
         executed and delivered shall constitute an original and all such
         counterparts together constituting but one and the same instrument.

17.5     If any action or duty to be taken or performed under any of the
         provisions hereof would, apart from the provisions of this Clause, fall
         to be taken or performed on a day which is not a Business Day such
         action or duty shall be taken or performed on the Business Day next
         following such date.

17.6     The benefit of this Agreement, the documents referred to herein, each
         of the Warranties and the Deed of Indemnity may be assigned by the
         Purchaser to another Member of the Charles River Group without the
         consent of the Vendors (although the Purchaser shall inform the Vendors
         in writing of any such assignment) and such member shall accordingly be
         entitled to enforce each of the Agreement, the Warranties and the Deed
         of Indemnity against the Warrantors and the Vendors and against all of
         the other parties to any documents referred to herein or therein.

17.7     This Agreement shall enure to the benefit of and be binding upon each
         party's successors and permitted assigns and personal representatives
         (as the case may be) and the Vendors or the Warrantors cannot transfer
         any of their obligations or rights under this Agreement to another
         party without the prior written consent of the Purchaser.

                   SECTION 18 - GOVERNING LAW AND JURISDICTION

18.1     This Agreement and the documents to be entered into pursuant to it
         shall be governed by and construed in accordance with the laws of
         Ireland as the same are applicable to contracts to be

                                      -42-


         wholly performed in Ireland and the parties hereby submit to the
         non-exclusive jurisdiction of the Courts of Ireland to settle any
         disputes which may arise out of or in connection with this Agreement or
         its performance and accordingly that any suit, action or proceedings so
         arising may be brought in such courts.



IN WITNESS whereof this Agreement had been entered into the day and year first
herein WRITTEN.




                                      -43-


                                 FIRST SCHEDULE
                                     PART I
                                    (VENDORS)



- --------------------------------------------------------------------------------------------------
   NAME AND ADDRESS OF THE               ADDRESS              ORDINARY SHARES          PERCENTAGE
           VENDORS

- --------------------------------------------------------------------------------------------------
                                                                                    
Susan Tavernor                 Shercot,                               5,500                  1.6%
                               Rignall Road,
                               Great Missenden,
                               Bucks, HP16 9PE

Angela Tavernor                32 Laxton Avenue,                      2,200                  0.6%
                               Hardwick,
                               Cambridge, CB3 7XL.

Nicola Tavernor                Shercot,                               5,500                  1.6%
                               Rignall Road,
                               Great Missenden, Bucks,
                               HP16 9PE

Eugene Caulfield               Knockbridge,                          33,000                  9.6%
                               Dundalk,
                               Co. Louth

Padraig Somers                 47 Yellow Walls Road,                  4,400                  1.3%
                               Malahide,
                               Co. Dublin

William Derek Tavernor         Shercot, Rignall Road,                33,000                  9.6%
                               Great Missenden,
                               Bucks, HP16 9PE

Eileen O'Connor                21 Moy Heights,                          550                 0.16%
                               Ballina,
                               Co. Mayo

Maureen Ruane                  3 Amana Estate,                         1650                  0.5%
                               Ballina
                               Co. Mayo.

Michael O'Brien                Larena,                                1,100                 0.32%
                               Ballingar,
                               Co. Sligo

Aileen Corcoran                Ballinahaglish,                        1,100                 0.32%
                               Ballina,
                               Co. Mayo

- --------------------------------------------------------------------------------------------------


                                      -44-




- --------------------------------------------------------------------------------------------------
   NAME AND ADDRESS OF THE               ADDRESS              ORDINARY SHARES          PERCENTAGE
           VENDORS

- --------------------------------------------------------------------------------------------------
                                                                                    
Maria Johns                    20 Mielview Court,                     1,100                 0.32%
                               Malahide,
                               Co. Dublin.

Joan O'Malley                  Church Street,                         1,100                 0.32%
                               Crossmolina,
                               Co. Mayo

Richard Caulfield              Bruff,                                 1,100                 0.32%
                               Aghamore,
                               Ballyhaunis,
                               Co. Mayo

Anne Chandler                  Comeragh,                             38,500                 11.2%
                               Ballinearrig Industrial
                               Estate,
                               Douglas Road,
                               Co. Cork

Catherine Caulfield            10 Gorse Cove,                        60,500                 17.5%
                               Foxford,
                               Co. Mayo

Frank Davis                    30 Parkview,                           6,600                  1.9%
                               Castleknock,
                               Dublin 15

Desmond Barry                  74 The Palms,                         11,000                  3.2%
                               Roebuck Road,
                               Dublin 14

Terry Moroney                  7, Roebuck Lawns,                     11,000                  3.2%
                               Dublin 14

Margaret  Connor               Erris Road,                            2,200                  0.6%
                               Crossmolina,
                               Co Mayo

David Tavernor                 64 Kents Green Lane,                   3,300                  1.0%
                               Haslington,
                               Crewe,
                               Cheshire, CW1 1TP

Leonard Moran                  4 Childers Heights,                  121,000                 35.0%
                               Ballina,                             -------
                               Co. Mayo.
                                                                    345,400
- --------------------------------------------------------------------------------------------------


                                      -45-


                                 SECOND SCHEDULE
   PARTICULARS OF DIRECTORS AND SECRETARY OF THE COMPANY AND THE SUBSIDIARIES

The Directors of the Company and the Subsidiaries at the date of this Agreement
are:-



- ---------------------------------------------------------------------------------------------------------------
NAME                                   ADDRESS                              DATE OF APPOINTMENT
- ---------------------------------------------------------------------------------------------------------------
                                    
Anthony Cremin                         Iceford
                                       Quay Road
                                       Ballina,
                                       Co. Mayo

Catherine Caulfield                    10 Gorse Grove
                                       Foxford
                                       Co. Mayo

Eugene Caulfield                       Knockbridge
                                       Dundalk,
                                       Co. Louth

William Derek Tavernor                 Sherot
                                       Rignall Road
                                       Greater  Missenden
                                       Bucks HP16 5PE


The Secretary of the Company and the Subsidiaries at the date of this Agreement
is



- ---------------------------------------------------------------------------------------------------------------
NAME                                   ADDRESS                              DATE OF APPOINTMENT
- ---------------------------------------------------------------------------------------------------------------
                                                                      
Margaret Connor                        Erris Road                           17/10/1994
                                       Crossmolina
                                       Co. Mayo





                                      -46-


                                 THIRD SCHEDULE
                                  SUBSIDIARIES


                                                  
NAME:                                                Entomology Europe Limited

REGISTERED NUMBER:                                   257045

REGISTERED OFFICE:                                   Carrentrila, Ballina, Co. Mayo

DATE AND PLACE OF INCORPORATION:                     19 November, 1996, Ireland

DIRECTORS:                                           Anthony Cremin
                                                     Catherine Caulfield
                                                     Eugene Caulfield
                                                     William Derek Tavernor

SECRETARY:                                           Margaret Connor

AUDITORS:                                            Russell Brennan Keane
                                                     RBK House,
                                                     Irishtown,
                                                     Athlone,
                                                     Co. Westmeath

AUTHORISED CAPITAL:                                  euro 126,973.80 divided into 100,000 ordinary shares of
                                                     euro 1.269738 each

ISSUED CAPITAL:                                      100

SHAREHOLDERS:                                        Biological Laboratories Europe Limited

                                                     No. of Shares: 100



                                      -47-



                                                  
NAME:                                                Saothorlanna Bitheolaiocha Idirnaisiunta Teoranta

REGISTERED NUMBER:                                   278971

REGISTERED OFFICE:                                   Carrentrila, Ballina, Co. Mayo

DATE AND PLACE OF INCORPORATION:                     20 January, 1998, Ireland

DIRECTORS:                                           Anthony Cremin
                                                     Catherine Caulfield
                                                     Eugene Caulfield
                                                     William Derek Tavernor

SECRETARY:                                           Margaret Connor

AUDITORS:                                            Russell Brennan Keane
                                                     RBK House,
                                                     Irishtown,
                                                     Athlone,
                                                     Co. Westmeath

AUTHORISED CAPITAL:                                  euro 634,869 divided into 500,000 ordinary shares of euro 1.269738
                                                     each

ISSUED CAPITAL:                                      300,100

SHAREHOLDERS:                                        Biological Laboratories Europe Limited

                                                     No. of Shares:  300,100


                                      -48-


                                 FOURTH SCHEDULE
                                DEED OF INDEMNITY

















                                      -49-


                                 FIFTH SCHEDULE

                                   PROPERTIES

1.   The Company is entitled to be registered as full owner with absolute title
     of ALL THAT AND THOSE part of the lands of Beldagelly South situate in the
     Barony of Erris and County of Mayo being that part of the lands in Folio
     36160F of the Register County Mayo which are shown outlined in red on map
     attached to Transfer dated 22nd November 2000 between Coillte Teoranta and
     Biological Laboratories (Europe) Limited, the registration of which
     Transfer is currently pending under Dealing Number D2001SM001600H SUBJECT
     in part to and with the benefit of Lease dated 4th June 1987 and made
     between the Minister for Energy of the one part & Udaras na Gaeltachta of
     the other part for a term of 99 years from the first day of December 1986
     AND ALSO HELD for the unexpired residue of the term of the said Lease.

2.   The Company is entitled to be registered as full owner with absolute title
     of ALL THAT AND THOSE the lands hereditaments and premises comprised in
     Folio 3575F of the Register, County Mayo.

3.   The Company is entitled to be registered as full owner with absolute title
     of ALL THAT AND THOSE the lands hereditaments and premises comprised in
     Folio 17477F of the Register, County Mayo.

4.   The Company is entitled to be registered as full owner with absolute title
     of ALL THAT AND THOSE the lands hereditaments and premises transferred by
     Deed of Transfer dated 26th November 1996 between Leonard Moran and
     Biological Laboratories (Europe) Limited, and therein described as "ALL
     THAT AND THOSE part of the townland of Carrowntrelia, Barony of Tirowley
     and County of Mayo being part of the property registered on Folio 24768F of
     the Register, County of Mayo comprising 2.741 hecatres (6.775 acres) or
     thereabouts metric measure which said property is outlined in red on the
     map thereof annexed hereto and thereon lettered `A'."

5.   The Company is registered as full owner with possessory title of ALL THAT
     AND THOSE the lands hereditaments and premises comprised in Folio 34097F of
     the Register, County Mayo.


                                      -50-


                                 SIXTH SCHEDULE
                                   WARRANTIES

For the avoidance of doubt, for the purposes of this SIXTH SCHEDULE all
references to the Company shall mean and include where the context so admits or
requires:-

(a) The Company; and
(b) Each Subsidiary; and
(c) the Company and its Subsidiaries.

                                  G E N E R A L

The Warrantors hereby jointly and severally warrant:-

1. (a) All information relating to the Company and the Vendors contained in this
       Agreement is true and accurate. All information in the Disclosure Letter
       is true and accurate and the Vendors are not aware of any fact or matter
       or circumstances not disclosed in the Disclosure Letter which renders any
       such information untrue, inaccurate or misleading or the disclosure of
       which might reasonably affect the willingness of the Purchaser to
       purchase the Shares on the terms and conditions herein contained and so
       far as such information is expressed as a matter of opinion such opinions
       were when given and are at the date hereof truly and honestly held and
       not given casually or recklessly.

       (b) The Company is a company duly organised and validly existing under
           the laws of Ireland having full corporate authority to carry on its
           business as it is now being carried on and to own and operate its
           properties. The certified copy of the Memorandum of Association and
           the Articles of Association which has been furnished to the Purchaser
           are true and complete and has embodied therein or annexed thereto a
           copy of every such resolution or agreement as is referred to in
           Section 143 of the Companies Act and fully set out all rights
           attaching to each class of the share capital of the Company. The
           Company has at all times carried on its business in accordance with
           its Memorandum of Association and its Articles of Association.

       (c) This Agreement constitutes and the Deed of Indemnity will when
           executed constitute legal, valid and binding obligations on the
           Vendors and the Warrantors in the case of the Deed of Indemnity and
           the performance by the Vendors of their obligations under this
           Agreement and the Warrantors in the case of the Deed of Indemnity
           will not:-

           (i)   conflict with, or result in the breach of, or constitute a
                 default under any of the terms, conditions or provisions of any
                 agreement or investment to which the Company is a party, or any
                 provision of the Memorandum or Articles of Association of the
                 Company or any encumbrance, lease, contract, order, judgement,
                 award, injunction, regulation or other restriction or
                 obligation of any kind or character by which or to which any
                 asset of the Company is bound or subject;

           (ii)  relieve any person from any agreement or obligation to the
                 Company (whether contractual or otherwise), or enable any
                 person to determine any such obligation or any right or benefit
                 enjoyed by the Company or to exercise any right, whether under
                 an agreement with or otherwise in respect of the Company;

                                      -51-


           (iii) result in the creation, imposition, crystallisation or
                 enforcement of any encumbrance whatsoever on any of the assets
                 of the Company; or

           (iv)  result in any present indebtedness of the Company becoming due
                 and payable or capable of being declared due and payable prior
                 to its stated maturity.

                                     SHARES

2. (a) The Vendors are the registered and beneficial owners of the entire issued
       and allotted ordinary and voting share capital of the Company which is
       fully paid up and the Vendors have the right and authority to sell and
       transfer the full legal and beneficial ownership thereof to the Purchaser
       on the terms set out in the Agreement and free from any charge, lien or
       encumbrance of any kind and without the consent of any third party.

       (b) No shares in the capital of the Company have been issued or allotted
           and no transfer(s) of shares in the capital of the Company have been
           registered otherwise than in accordance with the Articles of
           Association of the Company for the time being in force.

       (c) There are no options, rights to call for or to acquire pre-emption
           rights or other agreements or arrangements (including conversion
           rights) in force which call or may call for the present or future
           issue, allotment or transfer of or accord to any person the right to
           call for the issue, allotment or transfer of any ordinary share or
           loan capital of the Company or affect the right to transfer the
           registered and/or beneficial ownership of any shares in the capital
           of the Company.

       (d) The entire issued share capital in the Company is fully paid up and
           there are no calls on any shares outstanding and the Company has not
           exercised any lien over any of the issued share capital.

       (e) The Company has not capitalised or agreed to capitalise any profits
           or reserves or agreed to pass any resolution to do so.

       (f) The Shares are not subject to any trust or other proprietary interest
           in favour of any person or body corporate arising under any contract,
           agreement, arrangement or transaction between any persons by
           operation of law by virtue of any financial contribution direct or
           indirect to the acquisition of the Shares.

       (g) The Shares are not subject to any application or orders under the
           Judicial Separation and Family Law Reform Act, 1989 and the sale is
           not a disposal for the purpose of defeating a claim for financial
           relief under that Act.

       (h) No person is entitled to receive from the Company any finder's fee,
           brokerage or other commission in connection with the purchase of
           shares contemplated by this Agreement.

       (i) None of the Vendors have pledged, charged, mortgaged or encumbered
           their shares in the Company.

       (j) (i)   the Company has fully complied with the terms of the Agreement
                 dated 30 September, 1998 between L. Moran, Catherine Caulfield,
                 Eugene Caulfield, Ann Chandler, D Tavernor, the Company and
                 Forbairt ("the Forbairt Agreement"). The rights attaching to
                 the Preference Shares (as defined in the

                                      -52-


                     Forbairt Agreement) are as set out in the First Schedule
                     thereto notwithstanding the Articles of Association of the
                     Company;

               (ii)  all dividends due and payable in respect of the Preference
                     Shares have been fully paid and there is no outstanding
                     liability or arrears in respect thereof;

               (iii) no offer in respect of the Preference Shares has been made
                     under paragraph 6 of the First Schedule to the Forbairt
                     Agreement.

               (iv)  The Redeemable Cumulative Preference Shares are owned
                     legally and beneficially by Forbairt.

         (k)   (i)   the Agreement dated 2 September, 1994 between the parties
                     listed as "the Promoters" of the First Part, the Company
                     and Forfas is terminated and no party has any claim arising
                     thereunder and the Company has no outstanding liability
                     thereunder;

               (ii)  the 160,000 Convertible Cumulative Redeemable Preference
                     Shares allotted thereunder have been redeemed and cancelled
                     and never reissued;

               (iii) The Convertible Loan Stock referred to in Section 1.2 of
                     the Forfas Agreement has been repaid in full and the
                     Company has no liability thereunder and Banque Nationale de
                     Paris have no claim against the Company arising thereunder;

               (iv)  the Convertible Redeemable Preference Shares referred to in
                     the Forfas Agreement were never converted to ordinary
                     shares.

                                  SUBSIDIARIES

3.      (a)    The Company has no subsidiaries within the meaning of Section 155
               of the Companies Act, 1963 other than those referred to in the
               THIRD SCHEDULE and the Company is not the holder of nor the
               beneficial owner of any share capital of any other company,
               whether limited or unlimited and whether incorporated in Ireland
               or elsewhere other than the Subsidiaries nor has it agreed to
               acquire any share or loan capital of any company and the
               Subsidiaries have not been subsidiaries within the beneficial
               ownership of any company other than the Company.

        (b)    The Company never had any beneficial or any other interest in the
               Share Capital of Biological Laboratories (Ballina) Limited,
               company number 52235 or Biological Laboratories Limited, company
               number 109325 or Seragon Limited, company number 107290 and the
               Company has no interest with or business relationship with
               Biological Laboratories (Ballina) Limited or Biological
               Laboratories Limited, company number. 109325 or Seragon Limited,
               company number 107290 and the Company has and never had any
               liability for any debts, losses or liabilities of any kind of
               Biological Laboratories (Ballina) Limited, Biological
               Laboratories Limited or Seragon Limited.

                         EVENTS SINCE THE RELEVANT DATE

4.       Since the Relevant Date:-

        (a)    the business of the Company has been carried on in the ordinary
               and usual course and so as to maintain the same as a going
               concern and without any interruption or alteration in the nature,
               scope or manner of such business and there has not been any

                                      -53-


               adverse change in the Company's net asset position or otherwise
               in its financial position, prospects or turnover and no further
               liability (actual or contingent and whether disputed or not) for
               Taxation (including deferred taxation) has arisen or is likely or
               will arise otherwise than as a result of transactions entered
               into by the Company in ordinary course of its business;

        (b)    save for disposals in the ordinary and proper course of business,
               the assets of the Company have been and now are in the possession
               or under the control of the Company;

        (c)    except in the ordinary course of business and in accordance with
               arrangements which have been fully disclosed in the Disclosure
               Letter to the Purchaser the Company has not borrowed or raised
               any money;

        (d)    there has not been any damage, destruction or loss (whether or
               not covered by insurance) affecting the shares owned by the
               Vendors in the Company, the properties or assets of the Company;

        (e)    (i)  there is not and has not been any dispute of any sort with
                    or in relation to any of the Company's employees; and

               (ii) there is not and has not been any similar other occurrence
                    or event which has affected or could reasonably be expected
                    to so affect the value of the shares owned by the Vendors in
                    the Company, the properties or business of the Company;

         (f)   the Company has not acquired any assets other than in the normal
               course of business nor has it acquired any assets of which the
               cost, or the value of the cost of which, exceeded euro 30,000 in
               the case of any one such asset or euro 100,000 in the case of any
               number of such assets;]

         (g)   no dividends or other distributions of profits, capital or income
               have been declared, made or paid by the Company to its
               shareholders and other than in the ordinary course of business or
               fluctuations in overdrawn current accounts with bankers no loan
               or other indebtedness or liability or subordinated loan capital
               or loan stock of the Company has been repaid in whole or in part
               or has become due to be repaid, paid or discharged before the
               date on which it was due to be repaid, paid or discharged under
               the terms on which it was borrowed or incurred or liable (with or
               without notice or lapse of time or both) to be declared so due;

         (i)   no share or subordinated loan capital or loan stock has been
               issued or agreed to be issued by the Company;

         (j)   the Company has not created, extended, granted or issued or
               agreed to create, extend, grant or issue any lease, tenancy,
               licence, mortgage, charge, lien, encumbrance, option, debenture
               or other security;

         (k)   the Company has not made any unusual augmentation in stock nor
               written up any fixed assets or stock;

         (l)   save for such resolution or resolutions as may be necessary so as
               to implement the terms and provisions of this Agreement, the
               Company has not passed any resolution by its members in general
               meeting or made any alteration to the provisions of its
               Memorandum of Association or Articles of Association;

                                      -54-


         (m)   the Company has not undertaken or authorised any capital
               commitment or (other than in the normal ordinary course of
               business) disposed or agreed to dispose of any capital asset;

         (n)   the Company has not written off any debts;

         (o)   the Company has not done or omitted to do anything which would
               entitle any third party to terminate any contract or any benefit
               enjoyed by the Company or call in any money before the normal due
               date thereof;

         (p)   no employee or officer of the Company holding a position of
               material importance to the management of the Company's business
               has given or received notice terminating his employment and the
               Warrantors are not aware of any reason why any employee or
               officer of managerial position may give notice terminating his or
               her employment;

         (q)   no changes to the terms of employment or engagement of any
               director, employee or consultant have been proposed or made
               whether by the Company or any third party (or where employment or
               retention in the case of any consultant commenced subsequent to
               the Relevant Date, then since that date);

         (r)   the Company has not entered into any transactions or assumed or
               incurred any material liabilities (including contingent
               liabilities) or made any material payment otherwise than in the
               ordinary course of carrying on its business and "material
               liability" for the purposes of this clause (r) shall be a
               liability of euro 50,000 or more in monetary terms;

         (s)   the Company's profits have not been affected to a material extent
               by inconsistencies in accounting practices, by the inclusion of
               non-recurring items of income or expenditure, by transactions
               entered into otherwise than in normal commercial terms or by any
               other factors;

         (t)   the Company has not entered into any unusual, long-term or
               material onerous commitments or contracts;

         (u)   its business has not been materially or adversely affected by the
               loss of any important customer or source of supply or by any
               abnormal factor not affecting similar businesses to a like extent
               and there are no facts which are likely to give rise to any such
               effects. The Warrantors are not aware of any reason why any of
               the Company's top ten customers would terminate their
               relationship with the Company and the sale and purchase of the
               Shares will not lead to a termination by any customer of its
               arrangements with the Company;

         (v)   it has not made or received any surrender relating to group
               relief or the benefit of advance corporation tax;

         (w)   it has paid its creditors in accordance with their respective
               credit terms;

         (x)   the Company has not received any notification of any kind from
               the Revenue Commissioners affecting in any way the company's
               entitlement to the 10% Corporation Tax rate;

         (y)   No animal rights groups or groups with similar activities have
               had any contact with the Company and the Vendors are not aware of
               any reason why such groups may be about to take any action
               against the Company.

                                      -55-


                                   BORROWINGS

5. (a)   The amounts borrowed by the Company (as determined in accordance with
         the provisions of the relevant instrument) do not exceed any limitation
         on borrowings contained in its Articles of Association or in any
         debenture or other deed or document or legislative provision binding
         upon it and the Company does not have as outstanding any loan capital,
         nor has it factored any of its debts, nor engaged in financing of a
         type which would not require to be shown or reflected in audited
         accounts or borrowed any money which it has not repaid, save for those
         borrowings disclosed in the Disclosure Letter. The total amount of the
         Company's indebtedness does not exceed euro 170,000.

         (b) Save with regard to bank borrowings which do not exceed the
             overdraft or loan facilities available to the Company (particulars
             of which have been disclosed in the Disclosure Letter) the Company
             has no actual or contingent liability of any kind to any person or
             to any governmental or local authority in respect of borrowings;

         (c) The amounts and other material particulars of all loans,
             overdrafts, acceptance credits or other financial facilities,
             guarantees, mortgages, charges and debentures which have been given
             made or incurred by or assigned to or vested in the Company and are
             at the date hereof outstanding are accurately set out in the
             Disclosure Letter and are true and accurate in all respects.

         (d) The Company has no bank accounts or deposit accounts other than
             those disclosed in the Disclosure Letter showing the position as of
             the Business Day prior to the date hereof in relation to the credit
             and debit balances thereon and since such statements there have not
             been any payments out of any such accounts save for routine
             payments in the ordinary course of business the aggregate of which
             would not exceed euro ] and there are no amounts due to third
             parties or creditors in excess of a total aggregate amount of euro

         (e) As a result of the acquisition of the Shares by the Purchaser or
             any other thing contemplated by this Agreement none of the
             financial facilities available to the Company may be terminated or
             mature prior to its stated date of maturity.

                      OWNERSHIP OF ASSETS - STOCK IN TRADE

6.       (a) Except for assets disposed of by the Company in the ordinary course
             of business the Company is the owner of and has good and marketable
             title to all assets included in the Accounts and to the animal
             stock which is bred by the Company and all such assets comprise all
             the assets, property and rights which the Company uses for the
             purpose of or in connection with its business and are in the case
             of plant, machinery, vehicles, office equipment and stock-in-trade
             in a good state of repair and condition (fair wear and tear
             excepted) and in satisfactory working order and all such plant,
             machinery, vehicles, equipment and stock in trade are capable of
             being efficiently and properly used in connection with the business
             of the Company and none is dangerous, unsuitable or in need of
             removal or replacement and all animal stock is in good health and
             appropriate for use in the business and none is incapable of being
             used in the Business and in particular either in laboratory testing
             or veterinary trials.

         (b) The assets included in the Accounts (including all fixed and
             moveable plant, machinery, vehicles, equipment and stock in trade)
             and to the animal stock which is bred by the Company and all such
             assets and all assets acquired since the Relevant Date but less all
             assets disposed of since the Relevant Date:-

                                      -56-


             (i)   are free from any hire purchase, credit sale or rental
                   agreement, lien, option, mortgage, charge, lease, tenancy,
                   licence, covenant, condition, agreement or other encumbrance
                   whether relating to the asset itself or the use thereof;

             (ii)  are in the case of such parts of the Properties as comprise
                   leasehold property and leasehold buildings in a good state of
                   repair and decoration which (where appropriate) fully comply
                   with the Company's obligations contained in the instruments
                   by virtue of which the Company holds the same or is
                   interested therein; and

             (iii) are easily and readily accessible to the Company when
                   required by the Company.

         (c)       All the assets listed in the Accounts as at the Relevant Date
                   and the animal stock which is bred by the Company and all
                   such assets are the property of the Company free from all
                   encumbrances of any kind.

         (d)       The stock of animal stock now held are not excessive and are
                   adequate in relation to the current trading requirements of
                   the business of the Company; and none is unmarketable or
                   inappropriate or of limited value in relation to the current
                   business of the Company; and to the best of the belief of the
                   Vendors no contracts are outstanding which are likely to
                   change this.

         (e)       The Company has not purchased or agreed to purchase any
                   stock, goods or materials on terms that property in it does
                   not pass until full payment is made or all indebtedness
                   discharged.

         (f)       All items and documents delivered to the Company on the
                   acquisition or hire of any asset are in the possession of the
                   Company and where necessary any relevant documentation which
                   requires to be renewed and updated so as to ensure the
                   continued efficient and lawful operation of any such assets
                   has at all times been maintained in a proper way.

                                    INSURANCE

7.       Details of all existing insurance policies maintained by the Company
         are set out in APPENDIX ONE hereto copies of which are attached to the
         Disclosure Letter. All the assets of the Company which are of an
         insurable nature have at all material times been and are at the date of
         this Agreement insured to the full replacement or reinstatement value
         thereof against fire and other risks normally insured against by
         companies carrying on the same business as that carried on by the
         Company or owning property of a similar nature and the Company has at
         all material times been and is at the date of this Agreement adequately
         covered against accident, third party injury, damage, consequential
         loss, professional negligence and other risks normally covered by
         insurance by such companies. In respect of all such insurances:-

         (i)   all premiums have been duly paid to date;

         (ii)  all the policies are in full force and effect and are not
               voidable on account of any act, omission or non-disclosure on the
               part of the insured party and nothing has been done or omitted to
               be done which is likely to result in an increase in premium; and

         (iii) no claim is outstanding or may be made under any of the said
               policies and no circumstances exist which are likely to give rise
               to any claim.

                                      -57-


                                   EMPLOYMENT

8.       (a) Full particulars of the officers and employees of the Company,
             their date of birth, date of commencement of service, job
             description, their respective rates of pay and other benefits
             provided or which the Company is bound to provide (whether now or
             in the future) to each officer and employee of the Company and full
             particulars of all existing contracts of service with the directors
             or employees of the Company and of all consultancy agreements with
             the Company are as specified in APPENDIX TWO hereto and are true
             and complete and include particulars of all profit sharing,
             incentive and bonus arrangements to which the Company is a party
             whether legally binding on the Company or not.

         (b) Save to the extent (if any) to which provision or allowance has
             been specifically made in the Balance Sheet:-

             (i)   no liability has been incurred by the Company for breach of
                   any contract of service or for services, for redundancy
                   payments or for compensation for wrongful dismissal or unfair
                   dismissal or for failure to comply with any order for the
                   reinstatement or re-engagement of any employee; and

             (ii)  no gratuitous payment has been made or promised by the
                   Company in connection with the actual or proposed termination
                   or suspension of employment or variation of any contract of
                   employment of any present or former director or employee.

         (c) There are no schemes or arrangements in operation by or in relation
             to the Company whereunder any officer or employee of the Company or
             any other person is entitled to a commission, remuneration, bonus
             or other payment of any sort calculated by reference to the whole
             or part of the turnover, profits or sales of the Company.

         (d) The Company has not in existence nor has it promised to introduce
             any bonus scheme, incentive scheme, share incentive scheme, share
             option scheme or profit sharing scheme for all or any of its
             officers or employees or former employees.

         (e) The Company has, in relation to each of its officers and employees
             (and so far as is relevant to each of its former employees)
             complied with:-

             (i)   all obligations imposed on it by any statute, statutory
                   regulations, code of conduct and practice relevant to the
                   relations between it and its employees or any trade union and
                   has maintained current, adequate and suitable records
                   regarding the services of all such officers and employees
                   (including former employees);

             (ii)  all collective agreements, customs and practices for the time
                   being dealing with such relations or the conditions of
                   service of its employees;

             (iii) all relevant orders and awards made under any relevant
                   statute, regulation or code of conduct or practice affecting
                   the conditions of service of its employees; and

             (iv)  all obligations imposed by the European Communities
                   (Safeguarding of Employee Rights on the Transfer of
                   Undertakings) Regulations, 1980 and European Communities
                   (Safeguarding of Employees Rights on Transfer of
                   Undertakings) (Amendment) Regulations 2000 in relation to any
                   sale,

                                      -58-


                   purchase or other transfer coming within the terms of the
                   aforesaid regulations.

         (f) No moneys or benefits other than in respect of remuneration or
             emoluments of employment are payable to or for the benefit of or
             are receivable by any employee or officer of the Company and other
             than as detailed in Appendix Two hereto.

         (g) There are no amounts owing to any present or former directors or
             employees of the Company other than remuneration accrued for not
             more than one month or for reimbursement of business expenses.

         (h) There are no claims pending or threatened against the Company:-

             (i)   by an employee or workman or third party in respect of an
                   accident or injury which is not fully covered by the
                   insurance policies disclosed in APPENDIX ONE hereto; or

             (ii)  by an employee or director in relation to his terms and
                   conditions of employment or appointment.

         (i) Every officer and employee of the Company who should have been
             treated for tax purposes as employed by the Company has been so
             treated and disclosure has been made of all relevant correspondence
             with the Revenue Commissioners and other relevant government
             agencies.

         (j) The Company has complied with Section 14 of the Unfair Dismissals
             Act, 1977

         (k) Prior to Completion:-

             (i)   all pay related social insurance contributions (both
                   employer's and employees') due and payable by the Company
                   will have been duly paid;

             (ii)  all amounts due to the Revenue Commissioners in respect of
                   deductions which have been made or which should have been
                   made by the Company in accordance with PAYE regulations from
                   time to time in force have been deducted and have been paid
                   over to the Revenue Commissioners so that the Company will
                   not have any liability in respect thereof; and

             (iii) all certificates relating to matters referred to in this
                   paragraph which by law are required to be given by employers
                   to employees (as defined) have been given to all employees of
                   the Company and are true and accurate.

         (l) There are not in existence any contracts of service with directors
             or employees of the Company nor any consultancy agreements with the
             Company which cannot be terminated by three months notice or less
             or (where not reduced to writing) by reasonable notice without
             giving rise to any claim for damages or compensation (other than a
             statutory redundancy payment or statutory compensation for unfair
             dismissal).

         (m) Within a period of one year preceding the date of this Agreement
             the Company has not given notice of any redundancies to the
             Minister for Enterprise & Employment or started consultations with
             any trade union or unions under the provisions of Part II of the
             Protection of Employment Act, 1977 or Regulation 7 of the European
             Communities (Safeguarding of

                                      -59-





             Employees' Rights on the Transfer of Undertakings) Regulations 1980
             as amended by the European Communities (Safeguarding of Employees
             Rights on Transfer of Undertakings) (Amendment) Regulations 2000
             and the Company has not failed to comply with any such obligation
             under the said Part II or Regulation 7 as amended.

         (n) No employee of the Company is assigned or employed wholly or mainly
             outside Ireland.

                              INDUSTRIAL RELATIONS

9.       (a) The Company is not a party to any agreement with a trade union,
             staff association or other similar organisation other than those
             referred to in the Disclosure Letter and the Disclosure Letter
             contains details of all collective bargaining and procedural and
             other agreements or arrangements in existence relating to or
             relevant to any of the employees of the Company or current
             negotiations with any trade union, staff association or other
             organisation formed for a similar purpose which might affect the
             terms and conditions of employment of any employees.

         (b) The Company is not in any industrial dispute with any trade union
             or any other organisation and there is no such dispute pending,
             anticipated or threatened and the Vendors are not aware of any
             claim made on behalf of any employees of the Company by any trade
             union or other organisation. The Company has complied with all
             recommendations made by Industrial Relations Officers of the Labour
             Relations Commission, by Equality Officers or by the Labour Court.

         (c) The Company is up to date on all wage agreements and there is no
             material liability in respect of back pay which has not been
             reflected in the Accounts.

                                    PENSIONS

10.      (a) Full details of all retirement benefit schemes, death benefit
             schemes disability benefit schemes and sickness benefit schemes
             operated by the Company (in this paragraph 10 together called the
             "Scheme") are set out in APPENDIX THREE hereto.

         (b) All amounts due to the Trustees of the Scheme or to any insurance
             company in connection therewith and all contributions due by the
             Company have been paid.

         (c) The Company has fulfilled all its obligations in relation to the
             Scheme and the Scheme is a defined contribution scheme.

         (d) All lump sum death in service benefits (other than any refund of
             contributions) disability benefits which may be payable under the
             Scheme are fully insured.

         (e) No increase in contributions to any of the Schemes has been
             recommended in respect of any person who is employed, or deemed to
             be or treated as employed, by the Company at the date hereof and in
             respect of whom contributions are paid under the Schemes and no
             power to augment benefits nor any special discretion has been
             exercised under the Schemes except as disclosed in writing to the
             Purchaser and as set out in APPENDIX THREE. ALL CONTRIBUTIONS PAID
             BY THE COMPANY TO THE SCHEME ARE AS DETAILED IN APPENDIX TWO AND
             THE COMPANY HAS NO OTHER OBLIGATION TO MAKE ANY OTHER
             CONTRIBUTIONS. NO NOTICES, STATEMENT OR OTHER DOCUMENTS HAVE BEEN
             ISSUED IN RESPECT OF THE SCHEME WHICH WOULD LEAD A MEMBER OR
             POTENTIAL MEMBER TO BELIEVE THE SCHEME WAS NOT A DEFINED
             CONTRIBUTION SCHEME OR THAT THE AMOUNT WHICH THE

                                      -60-


             COMPANY IS LIABLE TO CONTRIBUTE IS MORE THAN 5% OF SALARY SAVE FOR
             THOSE CONTRIBUTIONS OVER 5% IN RESPECT OF THOSE INDIVIDUALS
             DISCLOSED IN THE DISCLOSURE LETTER.

         (f) The Scheme conforms with all applicable laws, regulations and
             requirements and the Scheme has been administered in accordance
             with its trusts, powers and provisions.

         (g) No claim has been made against the trustees or administrator of the
             Scheme or any of them or against any other person whom the Company
             is liable to indemnify or compensate in respect of any act, event,
             omission or other matter arising out of or in connection with the
             Scheme or any of them and the Vendors are not aware of any
             circumstances which may give rise to any such claim.

         (h) Except as disclosed in writing to the Purchaser as set out in
             APPENDIX THREE hereto there is no claim for nor is the Company
             under any legal or moral obligation to pay either now or at any
             time in the future any pension or make any other payment after
             death or retirement or in respect of disability or sickness or
             otherwise to provide any benefit to or in respect of any person and
             no such pension or payment or benefit is now being paid. Except as
             disclosed in writing to the Purchaser as set out in APPENDIX THREE
             hereto there are no ex-gratia pensions or other benefits currently
             or prospectively payable by the Company in respect of any person.

         (i) The Scheme is (where appropriate) an exempt approved scheme within
             the meaning of the Taxes Consolidation Act 1977 as amended and
             there is no reason why such exempt approval should be withdrawn.

         (j) The Vendors are not actually aware of any claim or contingent
             liability which will arise as a result of or in connection with any
             previous pension schemes of the Company.

         (k) All employees who have been receiving sick pay from the Company for
             a period in excess of one calendar month as at the date of this
             Agreement are listed in APPENDIX THREE hereto.

         (l) All actuarial consultancy legal audit investment management and
             other fees charges or expenses in respect of the Schemes payable by
             the Company have been paid.

         (m) All current or former employees who are or were eligible for
             membership of the Scheme were or are included in that Scheme or
             were offered membership and refused to join.

         (n) So far as the Vendors are aware, there are no disputes,
             arbitration, litigation or proceedings pending or threatened
             against either the Company or the Trustees in respect of the terms
             or provisions of the Scheme.

         (o) True copies of the trust deeds and rules constituting and governing
             the Scheme have been delivered to the Purchaser and except as may
             be expressed otherwise herein such documents are complete and up to
             date and satisfactory to ensure continued treatment of the Scheme
             as an exempt approved scheme as aforesaid.

         (p) True copies of all explanatory booklets and announcements and other
             material communications to employees relating to the Scheme has
             been delivered to the Purchaser and the Company has no obligation
             under the Scheme in respect of any present or former employee or
             director or any dependent of any of them other than under the
             documents referred to in the above paragraphs.

                                      -61-


                                   LITIGATION

11.      (a) The Company is not engaged in any litigation or arbitration
             proceedings or any industrial or trade dispute proceedings as
             plaintiff, accused or defendant and there are no such proceedings
             pending or threatened either by or against the Company, no
             injunction has been granted against the Company and there are no
             facts known to the Vendors after due and proper enquiry which are
             likely to give rise to any litigation and the Company is not
             subject to any order or judgement given by any Court and has not
             been a party to any undertaking or assurance given to any Court or
             governmental agency.

         (b) Neither the Company nor any of its directors, employees or persons
             for whom it is vicariously liable is or has been engaged in any
             litigation, prosecution, arbitration or other legal proceedings or
             in any dispute with the Revenue Commissioners, the Commissioners of
             Customs and Excise or any other authority or body of persons (in
             the case of directors, employees or such persons as aforesaid only
             so far as the Company may be vicariously liable) and there are no
             circumstances known to the Vendors or to the Company likely to give
             rise to the same or likely to entitle the Company to make any claim
             against any person.

         (c) The Company has not committed any criminal, illegal or unlawful act
             which is likely to affect the Company's ability to carry on its
             activities as heretofore or its financial position or
             profitability.

                                   WINDING-UP

12.      (a) No order has been made or petition presented, resolution passed or
             meeting convened or held for the winding-up of the Company; no
             distress, execution or other process has been levied on any asset
             of the Company; no receiver or examiner has been appointed or could
             be appointed by any person over its business or assets or any part
             thereof and there is no unfulfilled or unsatisfied judgement or
             court order outstanding against the Company.

         (b) The Company is not insolvent or unable to pay its debts within the
             meaning of Section 214 of the Companies Act, 1963 nor has the
             Company stopped or suspended payment of its debts nor has the
             Company sought from its creditors significant extension of time for
             payment of its debts.

         (c) No composition in satisfaction of the debts of the Company or
             scheme of arrangement of its affairs or compromise or arrangement
             between the Company and its creditors and/or members or any class
             of its creditors and/or members, has been proposed, sanctioned or
             approved.

         (d) No distress, distraint, charging order, garnishee order, execution
             or other process has been levied or applied for in respect of the
             whole or any part of any of the property, assets and/or undertaking
             of the Company.

         (e) No event has occurred causing, or which upon intervention or notice
             by any third party may cause any floating charge created by the
             Company to crystallise or any charge enacted by it to become
             enforceable nor has any such crystallisation occurred or is such
             enforcement in process.

                                      -62-


                            CONTRACTS AND COMMITMENTS

13.      (a) No guarantees, indemnities, mortgages, charges, debentures, liens,
             encumbrances or other security interests, have been given or made
             or incurred by or assigned to or vested in the Company other than
             as set out in the Disclosure Letter

         (b) The Company is not a party to any agency, distribution, marketing,
             purchasing, manufacturing, licensing agreement or arrangement, or
             any restrictive trading or other agreement or arrangement pursuant
             to which any part of its business is carried on, or which in any
             way restricts its freedom to carry on the whole or any part of its
             business in any part of the world in such manner as it thinks fit.

         (c) The Company has not given a power of attorney or any other
             authority (express, implied or ostensible) which is still
             outstanding or effective to any person to enter into any contract
             or commitment or do anything on its behalf, other than any
             authority to employees to enter into routine trading contracts in
             the normal course of their duties.

         (d) The Company is not nor has it agreed to become a party to, nor is
             any asset of the Company affected by:-

             (i)   any agreement or arrangement which is liable to be terminated
                   by another party or under which rights of any person
                   (including without limitation, any right to demand payment of
                   any indebtedness of the Company or to enforce any security
                   given by the Company) are liable to arise or be affected as a
                   result of any change in the control management and
                   shareholding of the Company pursuant to the terms of this
                   Agreement (nor is the Company liable to be required to give
                   any transfer notice or similar notice or take any action to
                   its disadvantage as a result of such change); or

             (ii)  any joint venture, consortium or partnership (including a
                   limited partnership) or other unincorporated association, or
                   any agreement or arrangement (whether verbal or written) for
                   participating with others in any business sharing commissions
                   or other income; or

             (iii) any trade association; or

             (iv)  any agreement or arrangement which cannot be terminated by
                   the Company on less than three months' notice without payment
                   of compensation.

         (e) (i)   Full details of all grants, subsidies, or financial
                   assistance applied for or received by the Company from any
                   governmental department or agency or any local or other
                   authority are set out in the Disclosure Letter together with
                   details of the Grant Agreements, the amount of the Grants
                   given, the amount undrawn and any liability to repay same;
                   and

             (ii)  the Company has not done or omitted to do any act or thing
                   which could result in all or any part of any investment
                   grant, employment subsidy or other similar payment made, or
                   due to be made, to it becoming payable or being forfeited or
                   withheld in whole or in part.

         (f) The Company is not under any obligation or a party to any contract
             which cannot readily be fulfilled or performed by it on time and
             without undue or unusual expenditure of money, effort or personnel.

                                      -63-


         (g) The Company is not a party to any contract or arrangement which
             involves the payment by it of amounts determined by reference to
             fluctuations in the index of prices or any other index or in the
             rate of exchange for any currency.

         (h) The Vendors do not have any knowledge of the invalidity of, or the
             grounds for rescission, avoidance or repudiation of, any agreement
             or customer arrangement to which the Company is a party and the
             Company has not received notice of any intention to terminate any
             such agreement and no lender to the Company has taken any steps to
             accelerate the maturity of any loan to the Company or to demand
             repayment thereof with or without the giving of notice or the lapse
             of time or satisfaction of any condition, is or may be entitled to
             do the same.

         (i) The Company has not entered into any transaction for the supply of
             goods or services to the Company by (or by the Company to) the
             Vendors or the Directors or employees of the Company or any of them
             and the Company is not dependent upon any one person or group of
             persons for more than 10% by value (averaged over any period of
             twelve months) of its business or supplies upon any one source.

         (j) The Company has not -

             (i)   issued any tender offer or quotation at any time which is or
                   will become capable of giving rise to a contract by an order
                   or acceptance by another party or parties save in the
                   ordinary course of business and on terms calculated to yield
                   a gross profit margin consistent with the prudent carrying on
                   of the business of the Company; or

             (ii)  omitted to do anything required or permitted to be done by
                   the Company necessary for the protection of its title to or
                   for the enforcement or the preservation of any order or
                   priority in respect of any property or rights owned by it, or

             (iii) entered into any transaction which is still executory and
                   which is unenforceable by the Company by reason of the
                   transaction being voidable at the instances of any other
                   party or ultra vires, void or illegal.

         (k) There is not outstanding and the Company has no continuing
             liability, commitment or obligation under or in respect of:-

             (i)   any contract of an unusual or onerous or long term nature; or

             (ii)  any obligation on the part of the Company to pay any royalty
                   or other similar periodic sums in the nature of royalties; or

             (iii) any agreement for the hire, rent, hire purchase or purchase
                   on deferred terms by the Company of any asset (other than the
                   Properties) excluding hiring and leases for periods of less
                   than one month and agreements in respect of which the annual
                   rental or payment does not exceed euro 20,000.

         (l) No substantial supplier or customer of the Company has ceased or is
             likely to cease trade with the Company within the next 12 months
             and the Company has received no notice of an intention to do so and
             details of such substantial suppliers and customers have been
             disclosed in the Disclosure Letter. For the purpose of this
             sub-paragraph (l) a substantial supplier shall mean any supplier
             who supplies in excess of 10% of the purchases of the Company. Full
             details of the Company's terms and conditions of trade with its
             substantial customers are detailed in the Disclosure Letter and
             there is

                                      -64-


             no provision in the Company's terms and conditions with such
             customers that would entitle such customers to terminate their
             trading relationship with the Company as a result of the change in
             control of the Company and the purchase of the Shares by the
             Purchaser.

         (m) The Company has no liability for and nothing has been brought to
             the Vendors or the Company's attention whereby the Company may
             become liable to any of their customers or third parties for
             results of any tests, trials or research conducted by the Company
             for any of its customers on products which relate to or in any way
             are concerned with or will be used in human health.

         (n) The Company is not a party to any contract whereby its liability
             thereunder will or could exceed the amount of the Company received
             in payment thereunder.

         (o) The Company has not done or omitted to do anything which has
             prejudicially affected its goodwill.

         (p) There has been no breach of any warranty, term, condition or
             undertaking or any false declaration made by the Company or any
             officer employee or agent of the Company in connection with any
             contract made by the Company and all of the Company employees sign
             confidentiality agreements in respect of all work undertaken by
             them as employees of the Company.

         (q) The Company is not nor has it been party to any transaction with
             any third party or parties which in the event of any such third
             party going into liquidation, receivership or an examination or a
             bankruptcy order being made in relation to it or him would
             constitute (in whole or in part) a transaction at an undervalue, a
             fraudulent preference, an invalid floating charge or part of a
             general assignment of debts which could be set aside against the
             company or person concerned.

         (r) No party to any agreement with or under an obligation to the
             Company is in default under it, being a default which would be
             material in the context of its financial or trading position; and
             there are no circumstances likely to give rise to such a default.

         (s) There is not now outstanding any contract or arrangement to which
             the Company is a party and which the Vendors or any director of the
             Company is or has been interested, whether directly or indirectly.

         (t) Maintenance contracts are in full force and effect in respect of
             assets of the Company which it is normal or prudent to have
             maintained by independent or specialist contractors and in respect
             of all assets which the Company is obliged to maintain or repair
             under any leasing or similar agreement; and all those assets have
             been regularly maintained to a good technical standard and in
             accordance with safety regulations usually observed in relation to
             assets of that description and in accordance with the terms and
             conditions of any applicable leasing or similar agreement.

         (u) The Company has not at any time prior to Completion sold or
             otherwise disposed of any shares or assets in circumstances such
             that it is, or may be, still subject to any liability (whether
             contingent or otherwise) under any representation, warranty or
             indemnity given or agreed to be given on or in connection with such
             sale or disposal.

         (v) In relation to any property or assets held by the Company under any
             hire purchase, conditional sale, chattel leasing or retention of
             title agreement or otherwise belonging to a third party, no event
             has occurred which entitles, or which upon intervention or

                                      -65-


             notice by the third party may entitle the third party to re-possess
             the property or assets concerned or terminate the agreement or any
             licence in respect of the same.

         (w) The Company has not manufactured, sold or supplied services which
             are or were or will become in any material respect, defective or
             unreliable or which do not comply in any material respect with any
             warranties or representations expressly or impliedly made by it or
             with all applicable regulations, standards and requirements.

         (x) The Company is not subject to any liability or obligation (save as
             may be implied by law) to change, alter, re-execute or otherwise do
             or not do anything in respect of any services or tests or trials
             that have been or are after the date of this Agreement agreed to be
             delivered by it.

         (y) Full details of all of the Company's Terms and Conditions with its
             customers are set out in detail in the Disclosure Letter.

                                    LICENCES

14.1     All necessary licences (including statutory licences and licences to
         use copyrights, patents and related rights), permits, consents and
         authorities (public and private) required by the Company under statute
         or otherwise have been obtained by the Company to enable the Company to
         carry on the whole and every part of its business effectively and
         lawfully in the places and in the manner in which such business is now
         carried on including but without prejudice to the generality of the
         foregoing all licences, consents, registrations and approvals required
         by the Company under the Cruelty to Animals Act, 1876, European
         Communities (Amendment of Cruelty to Animals Act, 1876) Regulations
         1994 (SI 17/1994), Animals Remedies Act, 1956 and Animal Remedies Act
         1993, Animal Remedies Regulations 1996 SI 179/1996, European
         Communities Animal Remedies and Medicated Feeding Stuffs) Regulations
         SI 176/1994, European Communities (Veterinary Medicinal Products)
         Regulations 1986 (SI 22/1986), European Communities (Disposal
         Processing and Placing on the Market of Animals By-Products)
         Regulations 1994 (SI 257/1994), European Communities (Control of
         Veterinary Medicinal Products and their Residues) Regulations 1990 SI
         171/1990; Medical Preparations (Licensing of Manufacture) Regulations
         1993 (SI 40/1993), Medicinal Products (Licensing and Sale) Regulations
         1998 (SI 142/1998) Radiological Protection Act 1991 and any regulations
         made thereunder, Animals Act, 1985, and all such licences, consents,
         permits and authorities are valid and subsisting and all conditions
         applicable to any such licence, consent, (including any planning
         consent) permit or authority have been complied with and the Vendors
         know of no reason why any of them should be suspended cancelled refused
         or revoked and none of the licences are or will be affected by a change
         in control of the Company.

14.2     All tests and practices carried on by the Company comply with the
         principles of good laboratory practice (GLP) in accordance with Council
         directive 1987/18/ EEC as amended by Directive 1999/11/EC, Council
         Directive 1988/320/EEC as amended by 1999/12/EC and the European
         Communities (Good Laboratory Practice) Regulations 1991 as amended by
         SI 294/1999. All of the Company's laboratories have had inspections and
         audits carried out as required under the aforesaid Directives and
         Regulations and the Company has not failed to obtain any certificate
         clearance or other authorisation unqualified and as required under the
         aforesaid Regulation and in particular the Company has an up to date
         Certificate from the National Accreditation Board (NAB) with regard to
         compliance by all of its laboratories as being compliant with Good
         Laboratory Practice.

14.3     All of the Company's premises, business practices and other relevant
         standards substantially comply with all legal requirements in all
         countries in which the Company carries on business

                                      -66-


         or where the results of those practices, standards or tests are used or
         are used by the Company's customers.

            INTELLECTUAL PROPERTY RIGHTS, TRADE SECRETS AND MARKETING

15.      (a) All patents, registered designs, know-how, trade secrets,
             copyright, trade marks and similar intellectual property rights
             used in the Company's Business (whether registered or not) and all
             pending applications therefor are (or where appropriate in the case
             of any pending applications will be):-

             (i)   legally and beneficially vested in the Company;

             (ii)  valid and enforceable;

             (iii) not being infringed or attacked or opposed by any person;

             (iv)  not subject to any licence or authority in favour of another;
                   and

             (v)   in the case of such rights as are registered or the subject
                   of applications for registration, disclosed fully in the
                   Disclosure Letter.

         (b) The processes employed and the products and services dealt in by
             the Company do not use, embody or infringe any patents, registered
             designs, know-how or trade secrets copyrights trade marks or
             similar intellectual property rights (whether registered or not)
             other than:-

             (i)   those belonging to the Company and referred to in paragraph
                   (a) above, or

             (ii)  those in respect of which licences have been obtained and are
                   currently in force, and are detailed in the Disclosure Letter
                   and no claims have been made and no applications are pending
                   of which the Vendors are aware which if pursued or granted
                   might be material thereto.

         (c) The Company has not disclosed or permitted to be disclosed or
             undertaken or arranged to disclose to any person any of its
             know-how, secrets, confidential information, price lists or lists
             of customers or suppliers.

         (d) The know how, secrets, confidential information and lists of
             customers and suppliers of the Company are all adequately
             documented.

         (e) The Company is not a party to any secrecy agreement or agreement
             which may restrict the use or disclosure of information forming
             part of the know-how or Intellectual Property.

         (f) All advertising and marketing materials and methods used by the
             Company comply with all legal requirements and other relevant
             standards and codes of practice in all countries in which those
             materials or methods are used by the Company and are not defamatory
             and there are no grounds on which such materials could be
             challenged for any reason whatsoever including without limitation
             defamation, trade libel or any other analogous law.

                                      -67-



                           DOCUMENTS BOOKS AND RECORDS

16.      (a) All documents relating to the Company required to be filed with the
             Registrar of Companies pursuant to the Companies Acts or any other
             statute or instrument in force have been duly filed and are correct
             in all respects.

         (b) The register of members of the Company accurately and sufficiently
             records the members from time to time of the Company and the
             Company has received no notice of any intended application or
             proceedings to rectify the said register.

         (c) All proper and necessary books of account, minute books, registers
             and records have been maintained by the Company, are in its
             possession or under its control and are up to date and accurate in
             all respects and contain accurate information in accordance with
             generally accepted accounting practices and principles relating to
             all transactions to which the Company has been a party.

         (d) All title deeds relating to the assets of the Company and an
             executed copy of all agreements to which the Company is a party,
             and the original copies of all other documents which are owned by
             or which ought to be in the possession of the Company are in its
             possession or under its control.

         (e) Each shareholder of the Company who is, or has at any time been
             required to notify the Company of its interests in any shares in or
             debentures of the Company pursuant to Section 53 of the Companies
             Act, 1990 has duly complied with its obligations under Part IV
             Chapter I of the said Act.

                                    STAMPING

17.      All documents which in any way affect the right, title or interest of
         the Company in or to any of its property, undertaking or assets, or to
         which the Company is a party and which attract stamp duty have been
         duly stamped within the requisite period for stamping and no document
         belonging to the Company which is subject to ad valorem stamp duty is
         unstamped or insufficiently stamped.

                              COMPLIANCE WITH LAWS

18.      (a) The Company has conducted its business substantially in accordance
             with all applicable laws, regulations, bye-laws, orders and safety
             standards in Ireland and in any relevant foreign country and there
             is not and there has not been any violation of or default with
             respect to, any statute, regulation, order, decree or judgement of
             any Court or any governmental agency or local or other authority of
             Ireland or other relevant foreign country which in consequence
             whereof an unfavourable judgement decision, ruling or finding would
             or could so far as the Vendors are aware have a material effect
             upon the assets or business or financial condition of the Company
             nor has the Company or so far as the Vendors are aware any of its
             officers committed any breach of any provision of its articles of
             association or of any trust deed, agreement or licence to which it
             is a party or of any covenant, mortgage, charge or debenture given
             by it.

         (b) Neither the Company nor so far as the Vendors are aware any of any
             of its officers, agents or employees during the course of their
             duties in relation to the Company has committed or omitted to do
             any act or thing the commission or omission of which is or could be
             in contravention of any act, order, regulation or the like (whether
             in Ireland or elsewhere) giving rise to any fine, penalty or
             default proceedings or other liability on its part.

                                      -68-


                                    COMPUTER

19.      (a) The Company has in force maintenance contracts for all items of
             computer hardware (including operating systems) which it uses and
             there is no reason to believe that those maintenance contracts will
             not be renewed by the other contracting party upon their expiry (if
             so required by the Company) upon substantially similar terms to
             those now applicable.

         (b) The Company has not suffered any failures or breakdowns of the
             computer hardware or software which it used in the year preceding
             the date of this Agreement.

         (c) The Company has operated and used all items of computer hardware
             used by it in accordance with the manufacturers recommendations
             including (without limitation) any recommendations as to
             environmental condition and power supply.

         (d) All computer software (including programs held on silicon chips,
             disks and any other media, manuals and operator guides) used by the
             Company is either owned by the Company or held by it on licence the
             terms of which have been disclosed in the Disclosure Letter.

         (e) The Company owns and has access to all documents and information
             (including source codes) which might be required to enable the
             Company to adapt, modify or improve such software economically and
             has the right to make such adaptations, modifications or
             improvements without the consent of any third party.

         (f) The Company has in force software support contracts for all current
             software licences held by the Company and there is no reason to
             believe that those contracts will not be renewed by the other
             contracting party upon their expiry (if so required by the Company)
             upon substantially similar terms to those now applicable.

         (g) The Company has not suffered any failures or bugs in or breakdown
             of such software (except arising from operator error not based on
             inadequate manuals) in the year preceding the date of this
             Agreement.

         (h) The Company has and is entitled to have back up copies of all
             software used by the Company which copies are to date fit for
             immediate use and stored in a secure place separate from the
             original copies of such software themselves.

         (i) The Company has not altered or modified any software held by it on
             licence or used by it whether with or without the consent of the
             owner or manufacturers thereof.

         (j) The Company has taken proper precautions to preserve the
             availability confidentiality and integrity of its computer systems
             and has had such systems reviewed regularly by independent experts
             in the field.

         (k) The Company is not aware of any case where fraud has been committed
             against the Company by use or abuse of its computer systems whether
             alone or in conjunction with any third party.

         (l) The Company has not altered, adapted or modified any software held
             by it on licence or used by it whether with or without the consent
             of the owner or manufacturers thereof.

                                      -69-


         (m) The Company has not got any of its record systems controls data or
             information recorded stored maintained operated or otherwise
             dependent upon or held by any means (including any electronic
             mechanical or photographic process whether computerised or not)
             which (including all means of access thereto and therefrom and use
             thereof) are not under the exclusive ownership and direct control
             of the Company; and

         (n) There has been no breach of any service or maintenance contract
             relevant to any such electronic mechanical or photographic process
             or equipment whereby any person or body providing services or
             maintenance thereunder may have the right to terminate such service
             or maintenance contract.

                                  BUSINESS NAME

20.      The Company does not carry on any part of its business under any name
         except its present corporate name and the Vendors have no interest of
         any kind in any other entity which trades under a similar name to the
         Company or includes the words "Biological Laboratories" in its name and
         the Vendors have no interest in any Company or other entity which could
         be regarded as being in competition with the Company or is involved in
         a business similar to the Business of the Company.

                                    DIRECTORS

21.      (a) The only directors of the Company are the persons whose names are
             listed in relation to each Company in THE SECOND SCHEDULE to the
             Agreement.

         (b) None of the persons who at present is a director or officer of the
             Company is ineligible to be a director by reason of the Companies
             Acts. For the purposes of this clause "director" includes any
             person occupying the position of director by whatever name called.

         (c) No person is a shadow director (within the meaning of Section 27 of
             the Companies Act, 1990) of the Company but is not treated as one
             of its directors for all the purposes of the Companies Acts, 1963
             to 2001.

         (d) None of the Directors or other officers of the Company has been
             declared by a Court to be a person to whom chapter I of Part VII of
             the Companies Act, 1990 applies, nor has any person been or is an
             auditor, Director or other officer in any way, whether directly or
             indirectly, concerned or taken part in the promotion, formation or
             management of the Company in breach of Section 160 of the Companies
             Act, 1990.

            COMPLIANCE WITH THE COMPANIES ACT, 1990 AS AMENDED BY THE
                       COMPANY LAW ENFORCEMENT ACT, 2001

22.      The Company has not:-

         (a) entered into any arrangement in breach of Section 28 or Section 29
             of the Companies Act, 1990 ("the 1990 Act");

         (b) made any loans or quasi-loans (within the meaning of Section 25 of
             the 1990 Act as amended by Section 75 Company Law Enforcement Act,
             2001 ("the CLE Act")), entered into any credit transactions as
             creditor or entered into any guarantee or indemnity or provided any
             security in connection with a loan, quasi-loan or credit
             transaction in breach of Section 31 of the 1990 Act as amended by
             the CLE Act;

                                      -70-


         (c) been and is not related to any other company for the purpose of
             Section 140 of the 1990 Act and is not and will not at any time be
             liable to be subject to an order made under that Section by virtue
             of any act (whether of commission or omission) that occurred prior
             to Completion;

         (d) had a notice served on it by its auditors pursuant to Section 185
             or 194 of the 1990 Act;

         (e) entered into any transaction or arrangement, particulars whereof
             would, pursuant to Section 41 of the 1990 Act, require to be
             contained in the Accounts proposed by the Company;

         (f) purchased or redeemed its own shares or those of its holding
             company or created treasury shares pursuant to the provisions of
             Part XI of the 1990 Act;

         (g) been struck off and subsequently restored to the register pursuant
             to Section 311A of the Companies Act, 1963 as amended; and

         (h) no shares in or debentures of the Company are subject to or have
             been issued in contravention of any restriction under Section 16 of
             the 1990 Act and the Company is not legally or beneficially
             interested in any shares in or debentures of any company which are
             the subject of any restriction under Section 16 of the 1990 Act.

                                   LIABILITIES

23.      Each shareholder of the Company who is, or has at any time been
         required to notify the Company of its interests in any shares in or
         debentures of the Company pursuant to Section 53 of the Companies Act,
         1990 has duly complied with its obligations under Part IV Chapter 1 of
         that Act.

24       No sums are owing by the Company to its auditors, solicitors or other
         professional advisers.

                                      GIFTS

25       Neither the Company nor any of its officers, employees or agents nor
         any other person acting on its behalf has directly or indirectly given
         or agreed to give any gift or similar benefit to any customer,
         supplier, governmental employee or other person who is or may be in a
         position to help or hinder its business or assist it in connection with
         any actual or proposed transaction.

                           RETURNS AND INVESTIGATIONS

26       (a) All appropriate returns and all relevant information have been
             supplied to the Revenue Commissioners, Customs and Excise,
             Department of Enterprise Trade & Employment, Department of Health &
             Children, Department of Finance, Department of Social Community and
             Family Affairs, Department of Agriculture, National Accreditation
             Board, Department of Public Enterprise and all other relevant
             governmental, municipal and local authorities in connection with
             the business of the Company and the same were and are complete,
             true and accurate.

         (b) Full details of all negotiations with and investigations and
             enquiries by any of the public authorities referred to in
             sub-paragraph (a) concerning any alleged or material liability (or
             alleged material liability), actual or contingent, of or any
             material act or omission of the Company (or any director employee
             or agent of the Company in such capacity) have been disclosed to
             the Purchaser and in respect of all such negotiations,
             investigations and enquiries full and frank disclosure of all
             material facts was made to

                                      -71-


             the public authorities concerned and all information supplied to
             them was true and accurate and there were and are no circumstances
             which would render any such information inaccurate, untrue or
             misleading.

         (c) There are not pending, nor in existence, any investigations or
             enquiries by or on behalf of any governmental or other body or
             local or other authority in respect of the affairs of the Company.

         (d) The Company has not had its affairs investigated pursuant to
             Sections 7, 8 or 9 of the Companies Act, 1990 (the "1990 Act") nor
             has there been any investigation of the ownership of the Shares of
             the Company pursuant to Sections 14 or 15 of the 1990 Act, nor has
             there been a direction made under Section 16 of the 1990 Act nor an
             investigation pursuant to Section 66 of the 1990 Act.

         (e) The Company is not the subject of or adversely affected by any
             Court Order made pursuant to Section 12 of the 1990 Act or
             otherwise the subject of or adversely affected by any proceedings
             instituted by or against any person as a result of any
             investigation of any Company's affairs under the 1990 Act.

         (f) The Company is not identified or referred to in any inspectors
             report made pursuant to Section 11 of the 1990 Act.

         (g) No directions have been given to the Company under or pursuant to
             Section 19 of the 1990 Act in relation to the production of
             documents.

         (h) The Company nor any of its shareholders have not been involved in,
             and no claim has been made in respect of any action under Section
             205 of the Companies Act, 1963 in relation to any of the Shares.

                                 COMPETITION LAW

27.      (a) The Company is not and has not been a party to, or engaged in, any
             agreement, arrangement, decision, concerted practice or activity
             which is prohibited by Section 4(1) of the Competition Acts 1991
             and 2002 (the "Competition Acts").

         (b) The Company has not made any notification to the Competition
             Authority requesting a licence pursuant to Section 4(2) of the
             Competition Acts or a certificate pursuant to Section 4(4) of the
             Competition Acts.

         (c) The Company has not committed, contrary to Section 5 of the
             Competition Acts , any abuse, either alone or jointly with any
             other undertaking, of a dominant position within the State or a
             substantial part of the State.

         (d) An authorised officer appointed pursuant to Section 20 of the
             Competition Acts has not entered and inspected any premises at or
             vehicles in or by means of which the Company carries on business
             nor required the Company nor any of its officers or agents to
             produce any books, documents or records and has not inspected,
             copied or taken extracts from any such books, documents and records
             nor required the Company nor any person to provide any information
             in regard to entries in such books, documents and records or in
             regard to the Company or its activities.

         (e) No petition has been presented by a person pursuant to Section 6(1)
             of the Competition Acts for an injunction or declaration or damages
             including exemplary damages in relation to any agreement decision,
             concerted practice or action in which

                                      -72-


             the company is or has been involved nor has any such injunction or
             declaration or damages been granted.

         (f) No petition has been presented by the Minister pursuant to Section
             6(4) of the Competition Acts for an injunction or declaration in
             relation to any agreement, decision, concerted practice or action
             in which the Company is or has been involved nor has any such
             injunction or declaration been granted.

         (g) The Company is not and has not been a party to, or engaged in, any
             agreement, arrangement decision, concerted practice, or activity
             which contravenes the provisions of any competition, anti-trust,
             anti-monopoly or anti-cartel law of any jurisdiction.

         (h) Neither the Company nor any of its officers or agents (during the
             course of their duties in relation to the business) has committed
             or omitted to do any act or thing the commission or omission of
             which is or could be in contravention of any Treaty Article,
             Regulation, Directive, Decision, Act, Order, Regulation or the like
             giving rise to any fine, penalty, default, proceedings or other
             liability in relation to the business of the Company.

         (i) The Company has not received any process, notice or communication,
             formal or informal, by or on behalf of the Competition Authority or
             the European Commission or any other authority of any country or
             any political or administrative sub-division thereof having
             jurisdiction in anti-trust or consumer protection matters in
             relation to any aspect of its business or any agreement arrangement
             or practice to which it is or is alleged to be a party and so far
             as the Vendors are aware no such process notice or communication is
             likely to be received

                           MERGER CONTROL LEGISLATION

28.      (a) No order has been made under the Mergers Act which directly or
             indirectly affects the business of the Company.

         (b) In relation to every merger or take-over in which the Company was
             involved prior to the date of this Agreement and to which the
             Mergers Act applied, the Minister has issued a statement in writing
             prior to completion of the merger or take-over concerned stating
             that he had decided not to make an order under Section 9 of the
             Mergers Act in relation to the proposed merger or take-over.

         (c) The Minister has not referred any proposed merger or take-over in
             which the Company is or was involved and to which the Mergers Act
             applies to the Competition Authority for investigation pursuant to
             Section 7(b) of the Mergers Act.

         (d) The Company has not been the object of a report of the Competition
             Authority under Section 8(1) of the Mergers Act stating whether, in
             the opinion of the Authority, a proposed merger or take-over would
             be likely to prevent or restrict competition or restrain trade in
             any goods or services and would be likely to operate against the
             common good.

         (e) The Company has never been involved in any merger or take-over
             which should have been referred to the Minister under the Merger
             Acts but was not so referred and in particular but without
             prejudice to the generality of the foregoing the acquisition by
             Biological Laboratories Europe Limited of the entire issued share
             capital of Entomology Limited from Mr. Moran and Catherine
             Caulfield in 1 June, 1998 did not require notification to the
             Minister under the Mergers Act and the Acquisition

                                      -73-


             was approved by resolution of the shareholders of the Company
             pursuant to Section 29 of the Companies Act, 1990.

         (f) The Company has not received any process, notice or communication,
             formal or informal from any authority of any country in relation to
             any aspect of its business which notice process or communication
             was adverse to the business in any way.

                                 DATA PROTECTION

29.      No individual has claimed compensation from the Company under the Data
         Protection Act, 1988 as amended by the European Communities (Data
         Protection) Regulations, 2001 for loss or unauthorised disclosures of
         data, nor has the Company received any notice or allegation from either
         the Data Protection Registrar or a data subject alleging non-compliance
         with the data protection principles of that Act or prohibiting the
         transfer of data to a place outside Ireland.

                                   ENVIRONMENT

30.      For the purposes of this paragraph 30:-

         "ENVIRONMENTAL LEGISLATION" shall mean all applicable laws of Ireland
         or any local authority in Ireland (including common law) and European
         Community Law and the law of any relevant foreign country or authority
         within any such country and regulations having the force of law
         concerning the protection of human health or the environment or the
         conditions of the workplace or the generation, transportation, storage,
         treatment or disposal of toxic or special wastes, hazardous wastes,
         controlled wastes or any other wastes or disposal or treatment of
         animal carcas or other dangerous substances including but not limited
         to the Fisheries (Consolidation) Act, 1959, Local Government (Water
         Pollution) Act, 1977, the Local Government (Water Pollution)
         (Amendment) Act, 1990, the Local Government (Water Pollution)
         Regulations, 1978, the Air Pollution Act 1987, the Air Pollution Act,
         1987, (Licensing of Industrial Plant) Regulations, 1988, the Local
         Government (Planning and Development) Acts, 1963 to 1999, the Planning
         and Development Act 2000, Local Government (Planning and Development)
         Regulations 1994 to 2000, the Planning Regulations 2001, the Dangerous
         Substances Acts, 1972 and 1979, the Local Government (Sanitary
         Services) Acts, 1878-1964, European Communities (Control of Veterinary
         Medicinal Products and their Residues) Regulations 1990 (SI 171/1990),
         European Communities (Disposal Processing and Placing on the Market of
         Animal By Products) Regulations 1994 (SI 257/1994), the Safety in
         Industry Acts, 1955 and 1980, the Safety, Health and Welfare at Work
         Act, 1989, the Public Health (Ireland) Acts, 1878, the Public Health
         Acts (Amendment) Act, 1890, Fisheries Acts 1959 to 1991 and the
         Fisheries (Amendment) Act 1994 to 2001, the Litter Pollution Act 1997,
         the Environmental Protection Agency Act, 1992, the Waste Management
         Act, 1996, The Waste Management (Amendment) Act, 2001, the Waste
         Management (Use of Sewage Sludge in Agriculture) Regulations 1998, The
         European Communities (Waste) Regulations, 1979, The Waste Management
         (Licensing) Regulations 1997, the Waste Management (Permit) Regulations
         1998, the European Communities (Licencing of Incinerators of Hazardous
         Waste) Regulations 1998, Directive 94/67/EC on the incineration of
         Hazardous Waste, Directive 2000/76 on the incineration of Hazardous
         Waste and any other regulations made under the Waste Management Act
         1996 and Waste Management (Amendment) Act, 2001, the European
         Communities (Environmental Impact Assessment) Regulations 1989-1999,
         the Radiological Protection Act 1991 and all orders and regulations
         under any of the above legislation and as the same are from time to
         time varied or amended and any other statute or subordinate legislation
         code of practice guidance note or local government or other bye-laws
         relating to human health or the environment or the conditions of the
         workplace or the generation transportation storage treatment or
         disposal of Hazardous Items (hereinafter defined);

                                      -74-


         "Hazardous Items" means any waste as defined in the Waste Management
         Act 1996 as amended and include hazardous waste, commercial, household,
         industrial and municipal waste as therein defined and any kind of noise
         vibration smell fumes smoke soot ash dust grit chemicals leachate
         petroleum products noxious radioactive inflammable explosive dangerous
         or offensive gases or materials and any other substances of whatever
         nature which may cause harm to man or to the health of living organisms
         or to the environment or public health or welfare.

         (a) The Company has at all times complied with Environmental
             Legislation and there is nothing in on or over or under the
             Properties the presence existence or condition of which constitutes
             a breach of Environmental Legislation nor is or has there been any
             manufacturing storage generation servicing treatment disposal or
             other process carried on or at the Properties in such a way as to
             amount to a breach of the same.

         (b) All necessary permits, permissions, approvals, licences, consents,
             authorisations and registrations ("the Consents") required under
             Environmental Legislation with regard to the Properties or the
             business of the Company and/or any activities processes, tests and
             substances from time to time on the Properties or carried on by the
             Company have been obtained and made in the name of the Company.

         (c) any person to whom the Company has transferred the control of its
             waste has the appropriate waste collection permit or waste licence
             under the Waste Management Act 1996 or the Environmental Protection
             Agency Act, 1992 (and such waste collection permit or waste licence
             has not been revoked)

         (d) All Consents required under Environmental Legislation (or true and
             complete evidential copies of the same) are in the possession or
             under the control of the Company and there are no outstanding
             applications or appeals in relation to the same.

         (e) All statements made and all information supplied by or on behalf of
             the Company in support of applications made for the Consents were
             and remain true and accurate in all material respects.

         (f) All conditions attached to the Consents have in all material
             respects been complied with and no claims or proceedings have been
             made or issued or are contemplated or threatened alleging a breach
             of such conditions and all Consents are valid and subsisting and no
             communication has been received alleging that any Consent may be
             modified suspended, refused or revoked and there are no
             circumstances likely to give rise to modification suspension,
             refusal or revocation.

         (g) No writ, summons, order, enforcement notice, prohibition notice or
             other notice has been issued or served and no direction from any
             Government Office or of any public local or other statutory
             authority has been made with regard to the Properties or to the
             Company and/or any activities processes or substances or tests in
             or over or under the Properties or carried on by the Company
             pursuant to the Environmental Legislation or with regard to the
             presence of any Hazardous Items and no prosecutions have been
             instituted with respect thereto.

         (h) No offence has been committed on or in connection with the
             Properties or any activities processes or substances in on over or
             under the Properties or with the activities of the Company pursuant
             to Environmental Legislation.

         (i) No complaints have been made by any third party (including any
             employee or Government or Local Authority) with regard to the
             Properties and/or any activities

                                      -75-


             processes or substances in on over or under the Properties or with
             regard to any activities of the Company as the result of any actual
             or alleged breach of Environmental Legislation or the presence of
             any Hazardous Items and the Vendors are not aware of any
             circumstances which may lead to any such complaint.

         (j) No works have been carried out on the Properties by any public
             local or other statutory authority under Environmental Legislation
             or any other legislation in respect of which such authority is
             entitled to recover costs nor has the Company received any notice
             or any information indicating that it is or may be responsible for
             all or some portion of the costs of investigating treating
             containing removing from any place or otherwise addressing any
             Hazardous Items.

         (k) There are not on the Properties or have there been:-

             (i)   any genetically modified organisms as defined in Directives
                   90/219/EC and 90/220/EEC on the deliberate release into the
                   environment of genetically modified organisms;

             (ii)  carried on any activities requiring a licence under the
                   Radiological Protection Act, 1991;

             (iii) any hazardous waste (as defined in the Waste Management Act,
                   1996 (as amended));

             (iv)  carried on any activity requiring a licence for the purposes
                   of integrated pollution control under the First Schedule to
                   the Environmental Protection Agency Act, 1992; or

             (v)   any offence under the Litter Act, 1982;

         (l) The Properties have not been affected by any landfill gas or other
             contaminants nor is or has there been used disposed of generated
             stored transported dumped released deposited burned or emitted any
             Hazardous Items at on from or under the Properties or at on from or
             under any other premises.

         (m) There is not nor has there been any leaking of any gas liquid or
             other material of any kind into over or under the Properties from
             any adjacent land or premises in third party ownership.

         (n) No Hazardous Items have been spilled released discharged or
             disposed of in the soil or water in under or upon the Properties or
             in any of the buildings comprised in the Properties and there has
             been no loss, spillage, accident or other development which the
             Company is obliged to notify the Local Authority or the
             Environmental Protection Agency or both about (under Section 32 of
             the Waste Management Act, 1996).

         (o) The Company has not received nor applied for any grants or funds
             from any public local or other statutory authority in connection
             with environmental improvements or reclamation on the Properties.

         (p) The Vendors are not aware of any proposed health safety or
             environmental requirements (whether in relation to the Properties
             or any activities processes or substances from time to time on the
             Properties or from time to time carried on by the Company) which if
             adopted would have a material adverse impact upon the Company.

                                      -76-


         (q) The Company is not the subject of any public or private litigation
             or proceedings involving a demand for damages or equitable relief
             or other potential liabilities with respect to any violation or
             alleged violation of any Environmental Legislation.

         (r) There has not been disposed of, spread, buried or incinerated on
             the Properties any animal carcass or part of any animal or any
             product of animal origin (including waste).

                                     BRANCH

31.      The Company has outside Ireland no branch, agency or place of business
         or any permanent establishment.

                            VENDORS' OTHER INTERESTS

32.      The Vendors do not have any rights or interests, directly or
         indirectly, in any business other than that now carried on by the
         Company which are or are likely to be or become competitive with the
         business of the Company, save as registered holder or beneficial owner
         of any class of securities of any company which is listed on the Stock
         Exchange and in respect of which the Vendors hold and is beneficially
         interested in less than 5 per cent of any single class of the
         securities in the company.

                                    ACCOUNTS

33.      The Accounts have been prepared in accordance with the law and on a
         basis consistent with that adopted in preparing the annual accounts of
         the Company for the previous 3 financial periods in accordance with
         accounting principles, standards and practices generally accepted in
         Ireland at the date of this Agreement and give a true and fair view of
         the state of affairs of the Company as at the Relevant Date and of its
         assets, liabilities and profits or losses as at that date or for the
         periods concerned and the audited balance sheet of the Company and the
         audited profit and loss account of the Company for the period ended on
         the Relevant Date have been prepared in accordance with the law and in
         accordance with accounting principles, standards and practices
         generally accepted in Ireland at the date of this Agreement and give a
         true and fair view of the state of affairs of the Company as at the
         Relevant Date and its assets, liabilities and profits or losses as at
         that date or for the period concerned.

34       Adequate provision for all material liabilities as far as were known or
         had been ascertained or could be reasonably anticipated by the Company
         has been made in the Balance Sheet; there were no material capital
         commitments of the Company as at the Relevant Date except as noted; the
         Balance Sheet did not overstate the current or fixed assets, the
         valuation and depreciation rates used therein were on the same basis as
         in previous years and proper provision was made for bad and doubtful
         debts. The Balance Sheet contained sufficient provision to cover all
         Taxation for which the Company was on the Relevant Date or at any time
         thereafter may have become or may hereafter become liable to be
         assessed or to pay, or on, in respect of, or by reference to, the
         profits, gains, income or earnings of the Company for any period ending
         on or before the Relevant Date and in respect of all distributions,
         dividends, loans, advances and payments, paid, due, payable or made
         prior to the date hereof.

35.      Since the incorporation of the Company there has been no change in:-

         (a) the accounting policies followed by the Company and the Accounts
             have been prepared using the accounting policies detailed in
             Annexure C; or

         (b) the basis and method of valuing the stock or the basis and method
             of determining depreciation or of determining the amount of any
             asset or liability of the Company

                                      -77-


         of a kind which would have a material effect in relation to, or on the
         amount at which the item affected by the change is stated in the
         Company's audited consolidated balance sheet and profit and loss
         account at the Relevant Date.

36.      Since the incorporation of the Company none of the assets of the
         Company has been revalued.

37.      In the Accounts:-

         (a) redundant, obsolete, excessive or inadequate stocks of the Company
             has been written off or written down as appropriate in accordance
             with the accounting policy for inventories disclosed in the
             Accounts so that taken as a whole it is stated at an amount not in
             excess of net realisable value at the Relevant Date;

         (b) the basis of valuation for stock-in-trade -

             (i)   is in accordance with Statement of Standard Accounting
                   Practice No. 9 and is particularly described in the Statement
                   of Accounting Policies in the Accounts;

             (ii)  has remained substantially the same in respect of the
                   commencement and end of each of the accounting periods of the
                   Company for the last three years

         (c) depreciation has been provided in accordance with the accounting
             policy for tangible fixed assets as disclosed in the Accounts up to
             and including the Relevant Date.

38.      (a) The debts included in the Accounts and debts accruing to the
             Company since the Relevant Date up to the date hereof are valid and
             enforceable and will realise in the ordinary course of collection
             the full nominal amounts thereof except to the extent of the
             provision for bad or doubtful debts in the Accounts and no book
             debt is the subject of any dispute, litigation, counterclaim or
             set-off nor are there any circumstances which may make any book
             debt owed to the Company bad or doubtful.

         (b) Provisions for bad or doubtful debts have been calculated in
             accordance with the accounting policy for debts as disclosed in the
             Accounts.

39.      All accounts books ledgers and other financial records of the Company:-

         (a) have been properly maintained and contain records of all matters
             required to be entered therein by the Companies Acts;

         (b) do not contain or reflect any material inaccuracies or
             discrepancies; and

         (c) give a true and fair view and accurately reflect the transactions
             and matters dealt with as at the date stated therein.

40.      (a) The Accounts contain an unqualified report from the Auditors.

         (b) No audited accounts of the Company in the past five years had
             attached thereto an auditor's report which was qualified in any
             way.

41.      (a) The financial position and results shown by the Accounts or
             previous accounts of the Company for the last three years have not
             (except as therein disclosed) to any material extent been affected
             by any extraordinary or exceptional items or by inconsistencies of
             accounting practice or by the inclusion of non-recurring items

                                      -78-


             of income or expenditure or by transactions entered into otherwise
             than on normal commercial terms or by any other factor rendering
             such financial position and results unusual or misleading in any
             material respect.

         (b) Except as disclosed by the Accounts or previous accounts of the
             Company the profits of the Company for the year ended on the
             Relevant Date have not to a material extent been affected by any
             unusual or non-recurring income or expenditure or by any other
             factor rendering such profits for all or any such year
             exceptionally low or high.

42.      The Balance Sheet of the Company has:-

         (a) made adequate provision or reserve for or note of all the
             liabilities (whether actual or contingent and whether or not
             quantified or disputed) of the Company for which the Company has
             been and was at the Relevant Date or at any time thereafter may
             have become or may hereafter become liable to be assessed on or in
             respect of or by reference to the profits, gains, income or
             earnings of the Company for any period ending on or before that
             date and dividends or other distributions, loans or advances); and

         (b) made adequate provision or reserve for depreciation and
             amortisation of fixed assets (such fixed assets not having been
             re-valued upwards for the purposes of the balance sheets), for bad
             and doubtful debts, discounts, credits for overcharging,
             maintenance and rectification and for deferred tax on the basis
             disclosed in the Accounts and contain full notes as to all material
             contingent liabilities and any material capital commitments
             undertaken or authorised as at the Relevant Date.

43.      There are no facts or circumstances known to the Vendors which would
         cause the Vendors, if a balance sheet of the Company was being prepared
         as at the date of execution hereof to include in such balance sheet a
         provision in relation to such facts or circumstances.

44.      There are no commitments on capital account outstanding at the Relevant
         Date other than as set out in the Accounts.

45.      No guarantee has been executed or filed by or in respect of the Company
         pursuant to Section 17 of the Companies (Amendment) Act, 1986.

                                   PROPERTIES

         TITLE

46.      (a) The Properties comprise:-

             (i)   all the land and premises owned occupied or otherwise used by
                   the Company; and

             (ii)  all the estate interest right and title whatsoever (including
                   for the avoidance of any doubt interests in the nature of
                   options) of the Company in respect of any land or premises;

         (b) Those of the Properties which are occupied or used by the Company
             in connection with any business carried on by the Company are so
             occupied or used by right of ownership or under lease or licence
             and the terms of any such lease or licence permit such occupation
             and use.

                                      -79-


         (c) The Company is the legal and beneficial owner of the Properties and
             all fixtures and fittings at the Properties are the absolute
             property of the Company free from encumbrances.

         (d) The Company has a good and marketable title to the Properties free
             from all questions or doubts and has excepted and reserved to it
             all necessary and appropriate easements and other rights for the
             benefit of the Properties.

         (e) The information contained in the Fifth Schedule to the Agreement as
             to the tenure of the Properties the principal terms of the leases
             or licences under which the same are occupied or used by the
             Company and the principal terms of the tenancies or licences
             subject to and with the benefit of which the Properties are held is
             true and accurate in all respects.

         (f) Where the title to any of the Properties is unregistered it is
             properly constituted by and can be deduced from duly stamped
             documents of title which are in the possession or under the control
             of the Company. No event has occurred in consequence of which
             registration should have been effected at the Land Registry.

         (g) Where the title to any of the Properties is registered the Company
             is shown on the register thereof at the Land Registry as the
             registered owner with absolute title and where the Land Certificate
             in respect of any of such Properties has issued the Land
             Certificate is in the possession or under the control of the
             Company and where the Land Certificate has not issued no
             application has been made by or on behalf of the Company for its
             issue.

         ENCUMBRANCES

         (h) The Properties are free from any mortgage debenture or charge
             (whether specific or floating legal or equitable) rent charge lien
             or other encumbrance securing the repayment of monies or other
             obligation or liability whether of the Company or any other party.

         (i) The Properties are not subject to any liability for the payment of
             any outgoings other than local authority rates and in the case of
             leasehold properties the rents and service charges specified in the
             Leases under which the Properties are held.

         (j) The Properties are not subject to any covenants restrictions
             stipulations easements profits a prendre wayleaves licences grants
             exceptions or reservations overriding interests or other such
             rights the benefit of which is vested in third parties nor any
             agreement to create the same.

         (k) The Properties are not subject to any agreement or right to acquire
             the same nor any option right of pre-emption or right of first
             refusal and there are no outstanding actions claims or demands
             between the Company and any third party affecting or in respect of
             the Properties.

         (l) The Properties are free from any charge claim caution inhibition or
             notice and no matter exists which is capable of registration
             against any of the Properties.

         (m) There is no person who is in occupation (other than pursuant to any
             of the tenancies referred to in the Fifth Schedule) or who has or
             claims any rights or easements of any kind in respect of the
             Properties adversely to the estate interest right or title of the
             Company therein.

                                      -80-


         PLANNING MATTERS

         (n) For the purposes of sub-paragraphs (n) to (y) (inclusive) of this
             paragraph "the Planning Acts" means

             - The Local Government (Planning and Development) Acts 1963 to 1999
               and the Planning and Development Act, 2000) ;

             - The Building Control Act 1990

             as the same are from time to time varied or amended and any other
             statute or subordinate legislation relating to planning matters.

         (o) The use of each of the Properties is the permitted or lawful use
             for the purposes of the Planning Acts and no such use is subject to
             planning conditions of an onerous or unusual nature (including any
             of a personal or temporary nature).

         (p) All necessary permissions have been obtained for the purposes of
             the Planning Acts in respect of any development of the Properties
             and any subsequent alteration extension or other improvement of the
             same and no planning permission is of a personal or temporary
             nature or has been revoked modified or suspended or is the subject
             of a High Court challenge and no application for planning
             permission is either awaiting decision or the subject of any
             appeal.

         (q) Building regulation and bye-law consents and approvals and Fire
             Safety Certificates (where applicable) have been obtained in
             respect of the development of the Properties and any subsequent
             alteration extension or other improvement of the same.

         (r) Compliance is being made and has at all times been made in all
             respects with all planning permissions and building regulation and
             bye-law consents for the time being in force in relation to the
             Properties and with all orders directions and regulations made
             under the Planning Acts and all conditions attached thereto have
             been fully complied with.

         (s) no agreements or undertakings relating to the Properties have been
             entered into under any statutory provision or otherwise.

         (t) Compliance is being and has at all times been made with all
             statutory provisions relating to the Properties.

         (u) None of the Properties is listed as being of special historic or
             architectural importance or located in a conservation area nor are
             the Properties affected by any tree preservation orders.

         (v) All development charges monetary claims and liabilities under the
             Planning Acts or any other such legislation have been discharged
             and no such liability contingent or otherwise is outstanding in
             respect of the Properties.

         (w) None of the Properties is affected or likely to be adversely
             affected by any proposals contained in any development plan
             prepared or in the course of preparation in respect of the areas in
             which the Properties are situated.

         (x) All statements made and all information supplied by or on behalf of
             the Company in support of applications lodged for the grant of
             permissions or certificates under the

                                      -81-


             Planning Acts in respect of the Properties were and remain true and
             accurate in all material respects.

         (y) No enforcement notices warning notices or other notices have been
             issued by any local planning authority in respect of the Properties
             nor has any enforcement or other action (including the exercise of
             any right of entry) been taken by any such authority and the
             Vendors are not aware of any circumstances which may lead to the
             same.

         STATUTORY OBLIGATIONS

         (z) Compliance is being made and has at all times been made with all
             applicable statutory and bye-law requirements with respect of the
             Properties and in particular (but without limitation) with
             requirements as to fire precautions and means of escape in case of
             fire and with requirement under the Fire Services Act, 1981.

         (aa) There is no outstanding and unobserved or unperformed obligation
              with respect to the Properties necessary to comply with the
              requirements (whether formal or informal) of any local or other
              competent authority and the Company does not anticipate that it
              will be obliged to incur the expenditure of any substantial sum of
              money within the next two years for such purpose.

         (bb) There are not in force or required to be in force any licences,
              permits or other consents whether under statute or otherwise which
              apply to the Properties or relate to or regulate any activities
              carried on therein.

         ADVERSE ORDERS

         (cc) There are no compulsory purchase or demolition notices orders or
              resolutions affecting the Properties nor are the Vendors aware of
              any circumstances likely to lead to any being made.

         (dd) No notices have been served under the Derelict Sites Act 1990
              affecting the Properties nor are the Vendors aware of any
              circumstances likely to lead to any being served.

         CONDITION OF THE PROPERTIES

         (ee) The buildings and other structures on the Properties are in good
              and substantial repair and fit for the purposes for which they are
              at present used.

         (ff) There are no disputes with any adjoining or neighbouring owner
              with respect to boundary walls and fences or with respect to any
              easement right or means of access to the Properties.

         (gg) The principal means of access to the Properties are over roads
              which have been taken over by the local or other roads authority
              and which are maintainable at the public expense and no means of
              access to the Properties is shared with any other party nor
              subject to rights of determination by any other party.

         (hh) Each of the Properties enjoys the main services of water drainage
              electricity and gas through media located entirely on in or under
              the Properties and the passage and provision of such services is
              uninterrupted.

         (ii) None of the Properties is located in an area or subject to
              circumstances particularly susceptible to flooding.

                                      -82-


         (jj) No building or structure on the Properties has at any time been
              affected by structural damage or electrical defects or by timber
              infestation rising damp or disease.

         (kk) The Properties are not subject to any rights of common.

         (ll) None of the Properties is affected by past or present mining
              activity.

         (mm) None of the Buildings or other structures on the Properties
              contains in its fabric any:-

              (i)    high alumina cement or concrete;

              (ii)   calcium chloride cement;

              (iii)  calcium silicate bricks or tiles;

              (iv)   asbestos products;

              (v)    wood wool slabs in permanent shuttering form;

              (vi)   crocidolite;

              (vii)  untreated sea-dredged aggregates;

              (viii) alkali re-active aggregates;

              (ix)   urea formaldehyde;

              (x)    vermiculite plaster;

              (xi)   artificial slates;

              (xii)  lead based paints;

              (xiii) concrete curing accelerator;

              or any deleterious substances or any substances or materials
              generally known to be deleterious to health or safety or to the
              integrity of building.

         INSURANCE

         (nn) The Properties are insured in their respective full reinstatement
              value and for not less than three years' loss of rent and against
              third party and public liability claims to an adequate extent.

         (oo) All premiums payable in respect of insurance policies relating to
              the Properties which have become due have been duly paid and no
              circumstances have arisen which would vitiate or permit the
              insurers to avoid such policies.

         LEASEHOLD PROPERTIES

         (pp) The Company has paid the rent and observed and performed the
              covenants on the part of the lessee and the conditions contained
              in any leases (which expression includes underleases) under which
              the Properties are held and the last demand for rent (or receipts
              if issued) were unqualified and all such leases are valid and in
              full force.

                                      -83-


         (qq) All licences consents and approvals required from the lessors and
              any superior lessors under the leases of the Properties and from
              their respective mortgagees (if any) have been obtained and the
              covenants on the part of the lessee contained in such licences
              consents and approvals have been duly performed and observed.

         (rr) There are no notices negotiations or proceedings pending in
              relation to rent reviews nor is any rent liable at the date hereof
              to be reviewed and time is not of the essence in respect of any
              steps to be taken in the conduct of rent reviews.

         (ss) There is no obligation to reinstate any of the Properties by
              removing or dismantling any alteration made to the same by the
              Company or any predecessor in title to the Company.

         (tt) There is not outstanding and unobserved or unperformed any
              obligation necessary to comply with any notice or other
              requirement given by the lessor under any leases of the
              Properties.

         (uu) There are no circumstances which would entitle any such lessor to
              exercise any powers of entry or take possession or which would
              otherwise restrict the continued possession and enjoyment of the
              Properties.

         (vv) The Company does not have any continuing liability in respect of
              any other property formerly owned or occupied by the Company
              either as original contracting party or by virtue of any direct
              covenant having been given on a sale or assignment to the Company
              or as a guarantor of the obligations of any other person in
              relation to such property.

         (ww) The Company is in actual occupation of all parts of the Properties
              and the security of tenure provisions of the Landlord and Tenant
              Acts are not excluded nor is the right to compensation for
              disturbance and no notices have been served on or received by the
              Company under the Landlord and Tenant Acts.

         TENANCIES

         (xx) The Properties are held subject to and with the benefit of the
              tenancies (which expression includes sub-tenancies) as set out in
              the Fifth Schedule to the Agreement and none other.

         (yy) With respect to such tenancies there have been disclosed in the
              Fifth Schedule particulars of:-

              (i)   the rent and any rent reviews and with respect to rent
                    reviews whether they are upwards only the date for giving
                    notice of exercise of such reviews and the operative review
                    date;

              (ii)  the term and any rights to break or renew the term;

              (iii) the obligations of the landlord and tenant in respect of
                    outgoings repairs insurance services and service charge;

              (iv)  any option pre-emption or first refusal rights;

              (v)   the user required or permitted under the terms of the
                    tenancies;

                                      -84-





              (vi)   any entitlement of a tenant of the whole or any part of the
                     Properties to compensation on quitting the premises let to
                     him in respect of disturbance and improvements or
                     otherwise;

              (vii)  any unusual provisions;

              (viii) any sub-tenancies derived out of such tenancies.

         (zz)  The Vendors are not aware of any material or persistent breaches
               of covenant by a tenant of any of the Properties including the
               covenants to pay rent and no guarantor or surety has been
               released expressly or by implication.

         (aaa) All such tenancies are incapable of alienation without the
               previous written consent of the Company and prohibit absolutely:-

               (i)  the assignment underletting or parting with possession of
                    part (as opposed to the whole) of the premises comprised in
                    the same; and

               (ii) the sharing of possession or occupation of all or any of the
                    said premises.

         (bbb) All such tenancies are on full repairing and insuring terms so
               that the occupational tenants or other occupants are together
               contractually responsible to the Company (whether by way of
               service charge or otherwise) for payment of the whole of the
               rates and all outer outgoings (including but without limitation
               the insurance repair decoration maintenance and rebuilding of the
               Properties and amortisation of plant and machinery thereat)
               payable in respect of the Properties so that there is no residual
               liability on the part of the Company and all expenditure by the
               Company (other than rent payable under the leases vested in the
               Company) in respect of the Properties is recoverable by the
               Company and the Company as landlord is entitled to charge
               reasonable management fees.

         (ccc) No tenant or licensee has commuted any rent or licence fee or
               made any payment thereof before the due date thereof and no rent
               reviews are currently being negotiated.

         (ddd) None of the Properties or any part thereof is or was a family
               home within the meaning of the Family Home Protection Act 1976
               nor is affected by the provisions of the Family Law Act 1981, the
               Judicial Separation and Family Law Reform Act 1989 or the Family
               Law Act, 1995.

         (eee) None of the Properties are "specified buildings" within the
               meaning of the Local Government (Multi-Storey Building) Act,
               1988.

                                    TAXATION

47.      All taxation of any nature whatsoever or other sums imposed charged
         assessed levied or payable under the provision of applicable
         legislation relating to taxation for which the Company is liable as a
         result of any act or omission by the Company prior to Completion will
         if, and in so far as such taxation or other sums ought to be paid prior
         to or on Completion, have been paid at or before Completion and in
         particular, but, without prejudice to the generality of the foregoing,
         at Completion, all amounts due for payment to the Revenue Commissioners
         in respect of excise duty and of Value Added Tax in respect of goods or
         services supplied prior to Completion or goods imported prior to
         Completion or intra-community acquisition of goods and of all
         withholding taxes deductible prior to Completion and of income tax
         deductible prior to Completion under Schedule E by virtue of the
         P.A.Y.E. regulations from time to time in force will have been paid so
         that the Company will have no

                                      -85-


         liability in respect thereof and at Completion all Social Welfare and
         Pay Related Social Insurance contributions (both employer's and
         employees') and any other levies and impositions due in respect of the
         employees of the Company will have been duly paid.

48.      The Company is not liable nor has it at any time since the Relevant
         Date been liable to pay interest on overdue taxation.

49.      The Company has not acquired or disposed of any asset or entered into
         any transaction otherwise than by way of bargain at arm's length.

50.      The Company has not entered into any financing leasing or other
         agreement in which or in connection with which the Company has
         indemnified any other party against any claim, loss or other liability
         arising from any change in tax legislation or in the interpretation of
         tax legislation.

51.      There are set out in the Disclosure Letter full particulars of all
         differences between the accounting and taxation treatments of all items
         in the Accounts.

52.      There is no appeal by the Company pending against any assessment to tax
         and the Company is not in default in payment of any tax within the
         period prescribed for payment thereof.

53.      The Company has not committed any act nor made any omission which might
         constitute an offence under Section 1078 of the TCA. [aiding, abetting,
         assisting etc. tax evasion.]

54.      The Company has not been at any time, for taxation purposes, resident
         in any jurisdiction other than the Republic of Ireland nor has it been
         at any time managed or controlled in or from any country other than the
         Republic of Ireland and the Company has not at any time carried on any
         trade in any other country.

55.      The Company has for each accounting period up to and including the
         accounting period ending on 31 January, 2001 furnished the Company's
         Inspector of Taxes with full and accurate particulars relating to the
         affairs of the Company and also has properly and within the prescribed
         periods of time made all returns and given or delivered all notices,
         accounts and information required for the purpose of taxation and all
         such have been correct in all material respects and on a proper basis
         and none such are disputed by the Revenue Commissioners or other
         authority concerned, and the Company has made all claims which would be
         of benefit to it within the time limits laid down in the relevant
         legislation.

56.      The Company has submitted and the Revenue Commissioners have agreed
         computations of its taxable profits in respect of all periods up to and
         including the year ended on 31 January, 2001.

57.      The Company has not entered into or been a party to any schemes or
         arrangements designed partly or wholly for the purpose of avoiding
         taxation. The Company has not been involved in any "tax avoidance
         transaction" within the meaning of Section 811 of the TCA and no
         provisions of that Section apply to the Company in respect of any event
         (whether or not involving the Company) which took place before
         Completion or in respect of any series of events (whether or not such
         events or any of them involve such company) taking place partly before
         Completion and partly after Completion. [transactions to avoid tax
         liability].

58.      No act or transaction has been effected in consequence of which the
         Company is liable for any taxation primarily chargeable against any
         other person, including any other company.

                                      -86-


59.      The making of returns, payment or preliminary tax and all other
         requirements of Part 41 and Section 608(1), Section 717(2) and Section
         774(4) of the TCA complied with fully by the Company.

60.      No surcharge for late submission of returns under Section 1084 of the
         TCA has or will become payable by the Company in respect of any period
         prior to Completion nor have any claims to relief connected with the
         Company been restricted or will be restricted by Section 1085 of the
         TCA.

61.      No penalty under Section 1084 of the TCA has or will become payable.
         [application of penalties to self-assessment returns.]

62.      No notice of attachment has been served on the Company or in relation
         to any funds of the Company under subsection (2) Section 1002 of the
         TCA [attachment of defaulter's funds].

63.      A relevant person has not communicated in writing particulars of an
         offence or offences to the Company under Section 1079 of the TCA as
         defined in Section 1079 of the TCA [duties of auditor/tax advisers to
         report certain Revenue offences].

64.      The Company has complied in all respects with the reporting
         requirements of Part VII of the Finance Act 1992 as replaced by Part
         38, Chapters 3 and 4 and Section 1094 of the TCA.

65.      The provisions of the Waiver of Certain Tax, Interest and Penalties Act
         1993 particularly Sections 3 and 9 do not have application to the
         Company [Mandatory requirement to avail of the tax amnesty where
         applicable].

66.      No transaction has been effected by the Company in respect of which any
         consent or clearance from the Revenue Commissioners or other taxation
         authorities was required (i) without such consent or clearance having
         been validly obtained before the transaction was effected and (ii)
         otherwise than in accordance with the terms of and so as to satisfy any
         conditions attached to such consent or clearance and (iii) otherwise
         than at a time when and in circumstances in which such consent or
         clearance was valid and effective.

67.      Nothing has been done and no event or series of events has occurred or
         will as a result of any contract, agreement or arrangement entered into
         before completion occur, which might when taken together with the entry
         into or completion of this agreement cause or contribute to the
         disallowance to the Company of the carry forward of any losses or
         excess charges on income.

68.      The Company has never been refused a tax clearance certificate by the
         Revenue Commissioners requested under the provisions of Section 1095
         TCA or any other provisions relating to the obtaining of tax clearance
         certificates which it did not subsequently obtained.

69.      Where full disclosure for deferred taxation (in accordance with
         Standard Statement of Accounting Practice No 15 of the Institute of
         Chartered Accountants in Ireland) is not made in the Accounts full
         details of the amounts have been disclosed in the Disclosure Letter.

70.      CORPORATION TAX

         (a) The Company has not paid remuneration to its directors in excess of
             such amount as will be deductible in computing the taxable profits
             of the Company; and

         (b) The Company has not paid and will not pay remuneration or
             compensation for loss of office or make any gratuitous payment or
             any other payment in respect of management or other services
             rendered or to be rendered to the Company to any of its

                                      -87-


             present or former directors or employees which will not be
             deductible in computing the taxable profits of the Company.

71.      In respect of share option schemes under Section 10 of the Finance Act,
         1986 (i.e. share options granted before 29.1.92) as amended by the
         Finance Act 1992 (for share options granted on or after 29.1.92) (Refer
         Schedule 32, paragraph 7(1) of the TCA) no circumstances exist which
         would lead the Revenue Commissioners to withdraw approval of any such
         scheme or to contend that the Company is not a qualifying company
         carrying on a specific trade.

72.      In respect of profit sharing schemes under Part 17, Chapter 1 of the
         TCA no circumstance exists which would lead the Revenue Commissioners
         to withdraw approval of any such scheme.

73.      If any employee of the Company has benefited from Section 479 of the
         TCA no circumstance exists in relation to the Company which would lead
         to the withdrawal of the relief.

74.      The Company has not, within the meaning of Part 18, Chapter 1 of the
         TCA received payment in respect of professional services from an
         accountable person [withholding tax on professional fees].

75.      The Company has complied in all respects with the requirements of Part
         13 of the TCA (close companies).

76.      No loan or advance or payment has been made or consideration given or
         transaction effected falling within Sections 438 or 439 of the TCA.
         [loans or write-off of loans to shareholders.]

77.      The Company has duly complied with the requirements of Sections 238 and
         239 of the TCA [payments made under deduction of tax] and with the
         requirements of all other provisions relating to the deduction and
         withholding of tax at source up to the date hereof and all such tax
         which has become due to the Revenue Commissioners has been paid to the
         Revenue Commissioners

78.      The Company has never incurred any expense or paid any amount in
         consequence of which the Company has been or could be treated under
         Section 436 or Section 437 of the TCA as having made a distribution.
         [treatment of expenses as dividends.]

79.      The limitation on the meaning of "distribution" provided for by Section
         4 of the TCA does not apply to any financial arrangements of the
         Company. [ limitation on use of "Section 84" finance.]

80.      The Company is not affected by the amendments to Part 6, Chapters 1-6
         and Section 20 of the TCA. [Additional conditions in respect of
         "Section 84" loans].

81.      No action has been taken by the Company which would result in the
         withdrawal of any "Section 84" loans that the Company has with any
         financial institution, or in the terms of any such "Section 84" loans
         being altered in a manner that adversely affects the Company.

82.      Section 138 of the TCA [treatment of dividends on certain preference
         shares] does not apply to any dividend paid by the Company in respect
         of its preference shares.

83.      The Company has not made any claim for relief in respect of stock
         appreciation under Section 31 and 31A of the Finance Act 1975 or
         Section 26 of the Finance Act 1976 or Section 49 of the Finance Act
         1984, as applicable prior to the implementation of the TCA.

                                      -88-


84.      The Company has not effected or entered into any act transaction or
         arrangement of any nature whereby it has incurred or may hereafter
         incur any liability under or by virtue of any of Part 4, Chapter 8 of
         the TCA. [treatment of premiums on rental income].

85.      The Company has not surrendered any amount by way of group relief under
         the provisions of Part 12, Chapter 5 of the TCA [set-off within a
         group].

86.      The Company is not and will not at any time in the future become liable
         to make a subvention payment or any other payment for an amount
         surrendered by any other company under or in connection with the
         provisions of Section 411 of the TCA. [payment for group relief].

87.      The Company has not at any time:

         a)  repaid or redeemed or agreed to repay or redeem any shares of any
             class of its share capital or otherwise reduced or agreed to reduce
             its issued share capital or any class thereof; or

         b)  capitalised or agreed to capitalise in the form of shares,
             debentures or other securities or in paying up any amounts unpaid
             on any shares debentures or other securities any profits or
             reserves of any class or description or passed or agreed to pass
             any resolution to do so; or

         c)  provided capital to any company on terms whereby the company so
             capitalised has in consideration thereof issued shares loan stock
             or other securities where the terms of any such capitalisation were
             otherwise than by way of a bargain made at arm's length or where
             the shares loan stock or other securities acquired are shown in the
             Accounts at a value in excess of their market value at the time of
             acquisition.

88.      No allowable loss which has arisen or which may hereafter arise on the
         disposal by the Company of shares in or securities of any company is
         liable to be disallowed in whole or in part by virtue of the
         application of Section 621 of the TCA [transactions in a group] or
         Section 622 of the TCA [dividend stripping] [anti avoidance
         provisions.]

89.      No change of ownership of the Company has taken place in circumstances
         such that Section 401 of the TCA [change in ownership of Company:
         disallowance of trading losses] has or may be applied to deny relief
         for a loss or losses incurred by the Company.

90.      On a sale of any machinery and plant at the value thereof shown in the
         Accounts no balancing charge will be incurred.

91.      There has not been in respect of any accounting period any excess of
         distributable investment and estate income within the meaning of
         Section 434 of the TCA.

92.      The Company is entitled to relief up to 5 April 1990 under Sections 145
         and 146 of the TCA.

93.      The Company has not claimed relief under Part 6, Chapter 5, Part 14,
         Chapter 1 and Schedule 32 of the TCA.

94.      The Company has conducted its operations in accordance with the facts
         and circumstances advised to the Revenue Commissioners in 1996 which
         led them to issue their favourable ruling on 20 August, 1996 in
         relation to manufacturing relief.

95.      The Company has not entered into transactions by virtue of which it
         will be chargeable under Case IV of Schedule D in accordance with
         Section 815 of the TCA. [taxation of income deemed to arise on sales of
         certain securities e.g. government/semi-state stock.]

                                      -89-


96.      The restrictions on the use of capital allowances for certain leased
         assets as set out in Section 403 of the TCA do not have application to
         any transactions entered into by the Company. [use of capital
         allowances against leasing income only].

97.      The provisions of Section 272 and Section 317(3) of the TCA of the
         Finance Act 1986 do not apply to any expenditure incurred by the
         Company. [capital allowances net of grant].

98.      No circumstance exists in connection with the Company which would lead
         to the withdrawal of relief for investment in research and development
         as provided for in Chapter III of the Finance Act 1986, as applicable
         prior to the implementation of the TCA.

99.      The provisions of Section 1013 of the TCA do not apply to any
         transaction entered into by the Company. [limited partnerships: relief
         restrictions].

100.     The Company is not liable to any claim in respect of tax due under
         Sections 904, 530, 531, Part 18, Chapter 2 and Section 904 of the
         TCA.[tax deductions from payments to subcontractors in the construction
         industry.]

101.     The Company has not entered into any transaction as a result of which
         it could be assessed to tax under Part 22 Chapter 1 of the TCA [profits
         from land development] or Section 35 of the Finance Act 1965.
         [treatment of rental income as profits from land development].

102.     The utilisation of losses incurred or charges paid by the Company is
         not restricted by Section 454(1), 455 and 456 of the TCA. [10% losses
         against 10% profits].

103.     The amendments to Section 234 of the TCA dealing with the tax treatment
         of patent royalties and related distributions do not apply to the
         Company.

104.     No allowance in respect of capital expenditure is or may be restricted
         by virtue of the provisions of Part 9 or Section 234 of the TCA
         inclusive of the Finance Act 1988. [limitation on 100% write off]

105.     Neither the Company nor any of its Shareholders is affected by the
         restrictions on the Business Expansion Scheme relief which are
         contained in Part 16 of the TCA. [additional conditions for relief].

106.     The Company has not entered into or taken any steps the object of which
         is a transaction which comes or may come within Section 817 of the TCA.
         [schemes to avoid liability to tax under Schedule F].

107.     The Company does not beneficially own nor has it ever beneficially
         owned shares to which Section 155 and Section 489 of the TCA applies or
         may have applied. [removal of tax free status from certain dividends.]

108.     The amounts receivable by the Company in respect of the provisions of
         services and the sale of goods are regarded as amounts receivable from
         the sale of goods within the meaning of Sections 443 to 450 of the TCA.

109.     The tax benefit envisaged at the time of borrowing in respect of any
         loan under Sections 130, 133 and 134 of the TCA will under present
         legislation remain undiminished until such loan has been repaid.
         [restriction on the benefit and availability of "Section 84" loans.]

                                      -90-


110.     Any machinery or plant provided for use for the purposes of the trade
         of the Company after 1st April 1990 is used wholly and exclusively for
         the purposes of the trade of the Company. [Sections 283, 284, 300(1),
         304(3)(b), 316(3)] of the TCA].

111.     All expenditure in respect of which scientific research allowances have
         been claimed under Part 29, Chapter 2 TCA has been incurred solely on
         scientific research within the meaning of Section 763, TCA.

112.     The Company has not been involved in any property, investment scheme in
         respect of which the tax incentives on property investment are
         restricted by Section 408 of the TCA or Part 9 Chapter 2 of the TCA.

113.     The relevant rental period in respect of which a double rent allowance
         is available to the Company under Section 324 and Schedule 32,
         paragraph 14 of the TCA.

114.     The Company has not acquired any of its own shares (Sections 173 to 186
         of the TCA).

115.     The restrictions of capital allowances on holiday cottages do not apply
         to the Company (Section 405 of the TCA).

116.     The Company has not paid dividends out of patent income, export sales,
         relieved income or Shannon income to its executives (Sections 144, 145
         (II) and 234(3) to (8) of the TCA).

117.     No claims to relief connected with the Company has been or are
         restricted by Section 1085 of the TCA.

118.     The Company has not received notice under Section 70 of the Corporation
         Tax Act, 1976, [Shannon Airport: revocation of certain certificates].

119.     The Company has not received a notice under Section 446 of the TCA,
         requiring the Company to desist from an activity or revoking the
         certificate. [Custom House Docks Area].

120.     No reduction or withdrawal of relief has occurred under Section 222 of
         the TCA [relief from Corporation Tax in respect of certain dividends
         from a non-resident subsidiary].

121.     The Company does not own nor has it ever owned an asset which
         constitutes a material interest in an off-shore fund which is or has at
         any time been a non qualifying off-shore fund within the terms of
         Sections 740 to 747 of the TCA [off-shore funds].

122.     The Company has not been nor is it assessable to tax under Sections
         1034 or 1035 of the TCA.

123.     Where the Company has made elections under Section 168 of the TCA to
         account for Advance Corporation Tax on certain distributions, agreement
         in writing has been received from the recipient of said distributions.

124.     All group elections under Sections 22 of 457 of the TCA (lower rate of
         Corporation Tax) have been made in the requisite manner by the due
         dates.

125.     All trading losses and excess charges on income carried forward in the
         Company do not relate to activities which formed part of a trade
         separate from that currently been carried on by the Company.

                                      -91-


      ADVANCE CORPORATION TAX ("ACT") AND DIVIDEND WITHHOLDING TAX ("DWT")

126.     The Company has no liability to ACT under Sections 159 to 172 of the
         TCA.

127.     The Company has not made an election under Section 165 of the TCA.
         [group dividends] and no surrender has been made under Section 166 of
         the TCA [surrender of ACT.

128.     The Company is not affected by the provisions of Section 167 of the TCA
         [carrying forward of ACT where change in ownership of company] or
         Section 170 of the TCA. [application of ACT to interest on certain
         loans - transitional provisions re. S. 84 loans].

129.     The Company has never incurred any expense or paid any amount in
         consequence of which it has or could be treated under Sections 436 and
         437 of the TCA as having made a distribution.

130.     The Company has not made a distribution after 28 January 1992 out of:-

         a)  income deemed from exempted trading operations;

         b)  export sales relieved income under Sections 145 and 146 of the TCA;
             or

         c)  income from a qualifying patent or a distribution derived from
             income arising on a qualifying patent under Section 234 of the TCA.

131.     The Company has no outstanding liability to DWT under Chapter 8A, Part
         6 of the TCA.

132.     The Company has complied with the requirements of Chapter 8A, Part 6
         and Schedule 2A of the TCA.

         CAPITAL GAINS TAX

133.     The Company has not made any claim under Section 597 of the TCA
         [replacement of business assets: roll over relief] as respects the
         consideration for the disposal of or of its interest in any assets
         which are defined in the said Section 597 of the TCA (amended as
         aforesaid) as "the old assets" or under Section 605 of the TCA.

134.     The Company has not made any such transfer as is referred to in Section
         589 of the TCA [transfers at undervalue] or received any asset by way
         of gift as mentioned in Section 978 of the TCA.

135.     The Company has not been a party to or involved in any share for share
         exchange nor any scheme of reconstruction or amalgamation such as are
         mentioned in Schedule 2 of Part 19, Chapter 4 of the TCA under which
         shares or debentures have been issued or any transfer of assets
         effected.

136.     The Company has not entered into any transaction which has, will or may
         insofar as the Vendors are aware, give rise to a charge to tax under
         the provisions of the CGTA or the provisions of the 1976 Act relating
         to companies' capital gains or under the provisions of the Capital
         Acquisitions Tax Act 1976.

137.     The Company has no liability by virtue of the provisions of Section 571
         of the TCA. [chargeable gains accruing on disposals by liquidators].

138.     The Company has not made any claim under Section 1005 of the TCA
         [unremittable profits made abroad] and no tax liability has been
         deferred under any other provision of the TCA including Section 563(1)
         and Section 981 [e.g. instalment sales.]

                                      -92-


139.     The Company has not entered into any transactions which give rise to a
         liability under Section 90(11) and Part 20 or Part 21, Chapter 1 of The
         TCA. [capital gains tax group relief].

140.     There have been no claims under Sections 538 and 546 of the TCA
         [capital losses allowed where no sale].

141.     The Company has not entered into or taken any steps the object of which
         is a transaction which comes within or might come within Section 549 of
         the TCA [creation of capital gains tax losses.].

142.     The amendments to Section 623 of the TCA do not apply to the
         transaction [as detailed in this agreement]. [Company ceasing to be a
         member of a group through a tax-avoidance motivated liquidation.]

143.     The Company has not entered into any of the transactions to which Part
         21 of the TCA applies.

144.     The Company has not been involved in a scheme or arrangement to which
         Section 543 of the TCA applies.

145.     The Company does not hold or has not disposed of "new assets" under
         Section 631 of the TCA [receipt of shares for transfer of trade;
         deferment of capital gains tax].

         STAMP/CAPITAL DUTY

146.     The Company has duly complied with and has no liability under Sections
         2 and 134 SDCA

147.     All documents in the possession or under the control of the Company
         which attract stamp duty have been properly stamped.

148.     No relief, exemption or reduction has been obtained from companies
         capital duty or stamp duty and without prejudice to the generality of
         the foregoing no relief, exemption or reduction has been obtained from
         companies capital duty or stamp duty under Section 119 SDCA
         [reconstruction or amalgamation] or from stamp duty under Section 79 or
         80 SDCA[relief from capital and stamp duty in certain cases] which (a)
         has become liable to forfeiture or (b) may be forfeited in the future.

149.     All capital duty howsoever arising or payable including but not limited
         to any such arising or payable on any transaction referred to in
         Section 116 SDCA has been duly and promptly paid by the Company and
         there is no outstanding liability therefor or interest thereon.

150.     The Company has not executed an instrument in respect of which fines
         could be imposed on it pursuant to Section 8 SDCA.

151.     The Company is not liable for any penalty imposed by Section 15 SDCA.

152.     All other capital and/or stamp duty howsoever arising or payable has
         been paid by the Company and there is no outstanding liability therefor
         or interest thereon.

153.     The Company and its employees have not done or omitted to do anything
         which could give rise to a liability on the Company for a fine,
         penalty, interest, charge or additional duty under the SDCA, as
         amended.

                                      -93-


154.     All capital duty and/or stamp duty payable by the Company in respect of
         any of the transactions referred to in the following sections of the
         SDCA (as amended) has been duly and promptly paid by the Company so
         that there is no liability in respect thereof or any interest thereon.

         (a) Section 58 [stamp duty on security documents];

         (b) Section 116 [capital duty]; and

         (c) Section 117 and 118 [stamp duty on certain Companies Registration
             Office statements].

         VALUE ADDED TAX

155.     The Company is a registered and taxable person for the purposes of the
         Value Added Tax Acts and has complied in all respects with such
         legislation and all regulations made or notices issued thereunder and
         has maintained full complete correct and up to date records, invoices
         and other documents (as the case may be) appropriate or requisite for
         the purposes thereof.

156.     The Company is not in arrears with its payments or returns (including
         monthly control statements and listings and other relevant documents)
         or notifications under the Value Added Tax legislation regulations or
         notices or liable to any abnormal or non routine payment or any
         forfeiture or penalty or to the operation of any penal provisions
         contained therein.

157.     The Company has not been required by appropriate fiscal authorities to
         give security under the Value Added Tax legislation.

158.     No arrangement exists or has existed whereby pursuant to Section 8(8)
         of the Value Added Tax Act, 1972 and Regulation 5 of the Value Added
         Tax Regulation 1979 (as amended) the business activities of the Company
         are or were deemed to be carried on by any other person or the business
         activities of any other person are or were deemed to be carried on by
         the Company. Notification has not been received from the Revenue under
         Section 8(8) of the Value Added Tax Act 1972 including especially a
         notification in the absence of a request from the taxable persons'
         concerned.

159.     The Company has not availed of the procedure in Section 58 of the
         Finance Act, 1989 whereby a trader may account and make returns for VAT
         purposes other than after each two monthly taxable period.

160.     Circumstances do not exist whereby a refund of VAT due to the Company
         may be deferred under the provisions of Section 201(1)(A) of the Value
         Added Tax Act, 1972.

161.     The Company has not waived the exemption in respect of any exempted
         activity under Section 7 of the Value Added Tax Act, 1972.

         CAPITAL ACQUISITIONS TAX

162.     There is no unsatisfied liability to capital acquisition tax attached
         or attributable to the Shares and the Shares are not subject to a
         charge in favour of the Revenue Commissioners.

163.     No person is liable to capital acquisitions tax attributable to the
         value of any of the Shares and in consequence no person has the power
         to raise the amount of such tax by sale or mortgage of or by a
         terminable charge on any of the Shares.

164.     The Company has not entered into or taken any steps the object of which
         is a transaction which comes within Section 90 of the Finance Act 1989
         [arrangements reducing value of company's shares].

                                      -94-


         WEALTH TAX

165.     The Company has no outstanding liability for wealth tax under the
         Wealth Tax Act, 1975.

         PAYE/SOCIAL WELFARE

166.     The Company is registered for the purposes of regulations made under
         Sections 903, 986 of the TCA (PAYE regulations) and has complied in all
         respects with such regulations and has maintained full, complete,
         correct and up to date records appropriate or requisite for the
         purposes thereof. In addition, the Company has deducted PAYE tax from
         all payments in respect of which this tax should have been deducted.

167.     The Company is not in arrears with its payments or returns required
         under regulations made under Sections 903 and 986 of the TCA (PAYE
         regulations) or liable to any abnormal or non-routine payment or any
         forfeiture or penalty or to the operation of any penal provisions due
         to non-compliance with the said regulations.

168.     The Company has complied in all respects with Part II, Chapter I,
         Social Welfare Consolidation Act 1981, Health Contributions Act 1979,
         Youth Employment Agency Act 1981 and any regulations made under those
         Acts and has maintained full, complete, correct and up to date records
         appropriate or requisite for the purposes thereof and has not committed
         any offence under Section 115, Social Welfare Consolidation Act 1981
         and is not liable to any abnormal or non-routine payment or any
         forfeiture or penalty or to the operation of any penal provisions due
         to non-compliance with the said Acts and/or regulations.

169.     The Company has not availed of the Income Tax (Employments) Regulations
         1989 (S.I. No. 58 of 1989) whereby an employer may make remittances of
         PAYE deducted from his employees at longer intervals than the normal
         monthly remittance basis. [deferment of PAYE for small traders].

         CUSTOMS & EXCISE

170.     The Company has complied fully and accurately with all applicable
         requirements of Part 11 of the Finance Act 1992 and other legislation,
         statutory instruments, regulations notices and practices on or
         connected with customs and/or excise.

         MISCELLANEOUS

171.     The Company has not been a party to or otherwise involved in any
         transaction, scheme or arrangement to which any of the following
         provisions could apply:-

         a)  Part 28, Chapter 1 and Schedule 21 of the TCA. [purchase and sale
             of securities];

         b)  Sections 806 to 808 of the TCA. [transfer of assets abroad];

         c)  Section 426 and 427 of the TCA. [partnership involving companies :
             effect of arrangements for transferring relief];

         d)  Sections 586 to 588 of the TCA. [company reconstruction and share
             swap];

         e)  Section 930 of the TCA. [error or mistake claims];

         f)  Section 400 of the TCA. [Company reconstruction without transfer of
             ownership];

                                      -95-


         g)  Section 614 of the TCA. [Corporation Tax attributable to chargeable
             gains; recovery from shareholder];

         h)  Section 816 of the TCA. [Taxation of shares in lieu of cash
             dividends];

         i)  Section 1004 of the TCA [unremittable income].

172.     The Company has complied in all material respects with the provisions
         of the following Sections and with all regulations which have been made
         by virtue thereof:-

         (a) Section 980 of the TCA;

         (b) Part 8, Chapter 4 of the TCA] [deposit interest retention tax].





                                      -96-


                                  APPENDIX ONE

                        DETAILS OF INSURANCE (WARRANTY 7)



- -------------------------------------------------------------------------------------------------------------
POLICY NUMBER             LIABILITY COVER              RENEWAL DATE          PREMIUM         INVOICE DATE
- -------------------------------------------------------------------------------------------------------------
                                                                              euro
- -------------------------------------------------------------------------------------------------------------
                                                                                 
06ENP6031064              Engineering Insurance        18/06/01              452.13          27/02/02
- -------------------------------------------------------------------------------------------------------------
00210269/21/01            Private Motor                11/07/01              540.20          27/02/02
- -------------------------------------------------------------------------------------------------------------
06ENP6031064              Engineering Insurance        29/07/01              419.01          27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/22/03            Commercial Motor             13/11/01              153.00          27/02/02
- -------------------------------------------------------------------------------------------------------------
00210647/21/01            Comprehensive                17/01/02              1380.00         27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/04/06            Fire/Perils                  03/02/02              28,900.00       27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/04/07            Loss of Profits              03/02/02              15,153.05       27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/22/04            Commercial Motor             03/02/02              803.03          26/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/22/04            Commercial Motor             03/02/02              951.23          27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/22/02            Commercial Motor             03/02/02              960.00          27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/82/01            Custom Bond                  03/02/02              64.76           27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/04/02            Combined Liability           03/02/02              37,129.63       27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/04/02            Combined Liability           03/02/02              592.44          27/02/02
- -------------------------------------------------------------------------------------------------------------
06ENP6031064              Engineering Insurance        03/02/02              1571.64         27/02/02
- -------------------------------------------------------------------------------------------------------------
99OP243951                Personal Accident            03/02/02              93.96           27/02/02
- -------------------------------------------------------------------------------------------------------------
99OP243952                Personal Accident            03/02/02              93.96           27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/22/03            Commercial Motor             03/02/02              4604.37         27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/22/06            Commercial Motor             03/02/02              701.98          27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/25/01            Motor Contingency            03/02/02              114.27          27/02/02
- -------------------------------------------------------------------------------------------------------------
00210647/21/02            Third Party Only             03/02/02              591.00          27/02/02
- -------------------------------------------------------------------------------------------------------------
00210647/21/01            Comprehensive                11/02/02              1062.00         27/02/02
- -------------------------------------------------------------------------------------------------------------
00212029/21/01            Private                      19/02/02              295.13          27/02/02
- -------------------------------------------------------------------------------------------------------------



                                      -97-


                                  APPENDIX TWO

                        DETAILS OF EMPLOYEES (WARRANTY 8)






















                                      -98-


BIOLOGICAL LABORATORIES EUROPE LTD

EMPLOYEES AGE REPORT AS AT 23RD JANUARY, 2002



- -------------------------------------------------------------------------------------------------------------
EMP. NO.      FIRST NAME             SURNAME                 GENDER           START DATE        AGE
- -------------------------------------------------------------------------------------------------------------
                                                                                 
1             Aileen                 Corcoran                f                07.02.94          37
- -------------------------------------------------------------------------------------------------------------
2             Margaret               Connor                  f                07.02.94          38
- -------------------------------------------------------------------------------------------------------------
3             Mona                   McGloin                 f                04.10.00          24
- -------------------------------------------------------------------------------------------------------------
4             William                Cleere                  m                07.02.94          52
- -------------------------------------------------------------------------------------------------------------
5             Sharon                 Walsh                   f                24.05.99          24
- -------------------------------------------------------------------------------------------------------------
6             Frank                  Keane                   m                07.02.94          53
- -------------------------------------------------------------------------------------------------------------
7             Joan                   O'Malley                f                07.02.94          37
- -------------------------------------------------------------------------------------------------------------
8             Nuala                  Moran                   f                12.05.97          37
- -------------------------------------------------------------------------------------------------------------
10            Richard                Caulfield               m                07.02.94          45
- -------------------------------------------------------------------------------------------------------------
11            Maureen                Ruane                   f                07.02.94          39
- -------------------------------------------------------------------------------------------------------------
12            Josephine              Ruddy                   f                12.05.98          38
- -------------------------------------------------------------------------------------------------------------
13            Michael                Padden                  m                12.05.98          38
- -------------------------------------------------------------------------------------------------------------
14            Michael                Ruddy                   m                31.12.01          17
- -------------------------------------------------------------------------------------------------------------
15            Eileen                 O'Connor                f                07.02.94          36
- -------------------------------------------------------------------------------------------------------------
16            Mary                   Dunleavy                f                07.02.94          34
- -------------------------------------------------------------------------------------------------------------
17            Ann                    Murray                  f                07.02.94          36
- -------------------------------------------------------------------------------------------------------------
18            Mary                   Wilson                  f                02.04.01          51
- -------------------------------------------------------------------------------------------------------------
19            Vincent                Conlon                  m                05.05.98          43
- -------------------------------------------------------------------------------------------------------------
20            Kieran                 McCourt                 m                02.04.01          39
- -------------------------------------------------------------------------------------------------------------
21            Alva                   Trimble                 f                07.02.94          42
- -------------------------------------------------------------------------------------------------------------
22            Christina              Coggins                 f                07.02.94          58
- -------------------------------------------------------------------------------------------------------------
23            Gladys                 Lynch                   f                07.02.94          39
- -------------------------------------------------------------------------------------------------------------
24            Concepta               Barrins-McCafferty      f                07.02.94          42
- -------------------------------------------------------------------------------------------------------------
25            Catherine              Caulfield               f                07.02.94          47
- -------------------------------------------------------------------------------------------------------------
26            Paul                   Neary                   m                05.01.02          18
- -------------------------------------------------------------------------------------------------------------
27            Martin                 McHale                  m                07.02.94          54
- -------------------------------------------------------------------------------------------------------------
28            Bridget                Heffernan               f                07.02.94          42
- -------------------------------------------------------------------------------------------------------------
30            Jean                   Coen                    f                12.05.97          45
- -------------------------------------------------------------------------------------------------------------
31            Philip                 Irwin                   m                09.04.01          44
- -------------------------------------------------------------------------------------------------------------
32            Dermot                 Kelleher                m                07.02.94          48
- -------------------------------------------------------------------------------------------------------------
33            Martin                 Healy                   m                22.07.96          34
- -------------------------------------------------------------------------------------------------------------
35            Sabrina                Irwin                   f                22.07.96          23
- -------------------------------------------------------------------------------------------------------------
37            Jason                  Ruane                   m                31.08.98          24
- -------------------------------------------------------------------------------------------------------------
38            Mary                   Geraghty                f                27.05.99          28
- -------------------------------------------------------------------------------------------------------------
39            John                   Dodd                    m                12.05.98          37
- -------------------------------------------------------------------------------------------------------------
40            Padraig                Doherty                 m                05.05.98          41
- -------------------------------------------------------------------------------------------------------------
43            Vincent                Conlon Jnr              m                09.06.98          22
- -------------------------------------------------------------------------------------------------------------
44            Eileen                 Rooney                  f                06.07.94          49
- -------------------------------------------------------------------------------------------------------------
45            Martin                 Murphy                  m                18.07.94          38
- -------------------------------------------------------------------------------------------------------------
46            Patrick                Grady                   m                23.04.97          28
- -------------------------------------------------------------------------------------------------------------
47            Paul                   Gardiner                m                17.04.00          21
- -------------------------------------------------------------------------------------------------------------
49            Kieran                 McGuire                 m                09.10.00          27
- -------------------------------------------------------------------------------------------------------------
50            Mattie                 Gorman                  m                03.10.94          42
- -------------------------------------------------------------------------------------------------------------


                                      -99-




- -------------------------------------------------------------------------------------------------------------
EMP. NO.      FIRST NAME             SURNAME                 GENDER           START DATE        AGE
- -------------------------------------------------------------------------------------------------------------
                                                                                 
51            Ann                    Melvin                  f                19.06.00          38
- -------------------------------------------------------------------------------------------------------------
52            Annette                Forde                   f                19.06.00          27
- -------------------------------------------------------------------------------------------------------------
53            Brendan                Conway                  m                05.10.94          27
- -------------------------------------------------------------------------------------------------------------
55            Catherine              Sheridan                f                11.08.97          27
- -------------------------------------------------------------------------------------------------------------
56            Carmel                 Mitchel                 f                20.06.00          38
- -------------------------------------------------------------------------------------------------------------
57            James                  McKenna                 m                07.07.97          36
- -------------------------------------------------------------------------------------------------------------
58            John                   King                    m                28.05.01          28
- -------------------------------------------------------------------------------------------------------------
59            Thomas                 Killeen                 m                19.08.96          30
- -------------------------------------------------------------------------------------------------------------
61            Fionnuala              Garvin                  f                02.09.98          54
- -------------------------------------------------------------------------------------------------------------
62            Dolores                Needham                 f                07.10.96          46
- -------------------------------------------------------------------------------------------------------------
63            Edel                   Dolan                   f                07.10.96          32
- -------------------------------------------------------------------------------------------------------------
65            Michael                Neary                   f                27.02.95          63
- -------------------------------------------------------------------------------------------------------------
66            Vivian                 Healy                   m                09.03.95          29
- -------------------------------------------------------------------------------------------------------------
70            Catherine              Conway                  f                03.12.99          28
- -------------------------------------------------------------------------------------------------------------
71            Caroline               Conlon                  f                28.05.01          19
- -------------------------------------------------------------------------------------------------------------
72            Rory                   McStay                  m                18.10.99          43
- -------------------------------------------------------------------------------------------------------------
74            Michael                Gordan                  m                13.10.97          47
- -------------------------------------------------------------------------------------------------------------
75            Patricia               Kavanagh                f                04.11.96          34
- -------------------------------------------------------------------------------------------------------------
76            Claire                 Ickringill              f                28.05.01          20
- -------------------------------------------------------------------------------------------------------------
77            Caroline               Wilson                  f                28.09.98          33
- -------------------------------------------------------------------------------------------------------------
78            Bridget                Durcan                  f                04.12.95          35
- -------------------------------------------------------------------------------------------------------------
79            David                  McGuire                 m                17.04.00          28
- -------------------------------------------------------------------------------------------------------------
80            Una                    Casserly                f                08.12.99          32
- -------------------------------------------------------------------------------------------------------------
81            Patrick                Healy                   m                08.05.00          56
- -------------------------------------------------------------------------------------------------------------
82            Gerard                 McHale                  f                29.01.96          30
- -------------------------------------------------------------------------------------------------------------
83            Annette                Flynn                   f                21.11.97          26
- -------------------------------------------------------------------------------------------------------------
84            Angela                 Noone                   f                11.03.96          36
- -------------------------------------------------------------------------------------------------------------
85            Joseph                 Corcoran                m                21.09.98          29
- -------------------------------------------------------------------------------------------------------------
86            Keith                  Best                    m                21.03.96          27
- -------------------------------------------------------------------------------------------------------------
87            Kerry                  Moran                   f                29.09.98          25
- -------------------------------------------------------------------------------------------------------------
88            Melissa                Conlon                  f                05.06.01          19
- -------------------------------------------------------------------------------------------------------------
89            Jackie                 Leitch                  m                19.03.96          46
- -------------------------------------------------------------------------------------------------------------
90            Liam                   McHale                  m                02.09.96          28
- -------------------------------------------------------------------------------------------------------------
92            Martin                 Devaney                 m                02.12.96          30
- -------------------------------------------------------------------------------------------------------------
93            William                Clarke                  m                09.12.96          54
- -------------------------------------------------------------------------------------------------------------
95            Anne                   McLoughlin              f                20.01.97          35
- -------------------------------------------------------------------------------------------------------------
96            Suzanne                Morrow                  f                02.12.97          32
- -------------------------------------------------------------------------------------------------------------
97            Leonard                Moran                   m                03.02.97          53
- -------------------------------------------------------------------------------------------------------------
99            James                  Walsh                   m                09.10.00          37
- -------------------------------------------------------------------------------------------------------------
100           Charles                McHale                  m                16.10.00          28
- -------------------------------------------------------------------------------------------------------------
101           Michelle               Garrett Walsh           f                18.03.97          31
- -------------------------------------------------------------------------------------------------------------
102           John                   McGuinness              m                11.06.01          31
- -------------------------------------------------------------------------------------------------------------
104           Seamus                 Conroy                  m                01.04.97          28
- -------------------------------------------------------------------------------------------------------------
105           Geraldine              Ruddy                   f                30.12.97          37
- -------------------------------------------------------------------------------------------------------------
107           Declan                 Moran                   m                26.06.01          23
- -------------------------------------------------------------------------------------------------------------
109           Liam                   McHale (Ballina)        m                16.03.98          36
- -------------------------------------------------------------------------------------------------------------
110           Pat                    Foody                   m                07.07.98          55
- -------------------------------------------------------------------------------------------------------------
111           Joe                    Gillespie               m                25.06.01          16
- -------------------------------------------------------------------------------------------------------------
112           John                   Conway                  m                18.06.01          23
- -------------------------------------------------------------------------------------------------------------
113           Vincent                Kavanagh                m                21.06.99          31
- -------------------------------------------------------------------------------------------------------------
114           Mary                   Conlon                  f                28.06.99          42
- -------------------------------------------------------------------------------------------------------------


                                     -100-




- -------------------------------------------------------------------------------------------------------------
EMP. NO.      FIRST NAME             SURNAME                 GENDER           START DATE        AGE
- -------------------------------------------------------------------------------------------------------------
                                                                                 
116           Jerome                 Tuohy                   m                08.05.00          43
- -------------------------------------------------------------------------------------------------------------
118           Keith                  Timoney                 m                18.06.01          18
- -------------------------------------------------------------------------------------------------------------
119           Caroline               Ruane                   f                31.08.98          25
- -------------------------------------------------------------------------------------------------------------
120           Jackie                 Igoe                    f                16.07.99          33
- -------------------------------------------------------------------------------------------------------------
121           Emma                   Munnelly                f                27.10.98          29
- -------------------------------------------------------------------------------------------------------------
122           John                   Goodwin                 m                19.10.98          47
- -------------------------------------------------------------------------------------------------------------
123           Brian                  Monaghan                m                02.07.01          32
- -------------------------------------------------------------------------------------------------------------
124           Brian                  Moran                   m                03.07.01          40
- -------------------------------------------------------------------------------------------------------------
125           Joseph                 Foody                   m                03.11.98          52
- -------------------------------------------------------------------------------------------------------------
126           Sandra                 McHale                  f                04.01.99          23
- -------------------------------------------------------------------------------------------------------------
127           Collette               O'Carroll               f                04.01.99          25
- -------------------------------------------------------------------------------------------------------------
128           Bernadette             Gillespie               f                19.01.99          43
- -------------------------------------------------------------------------------------------------------------
130           Mary                   Langan                  f                27.01.99          44
- -------------------------------------------------------------------------------------------------------------
133           Patricia               Nolan                   f                23.07.01          40
- -------------------------------------------------------------------------------------------------------------
134           Helen                  McDonnell               f                19.03.99          41
- -------------------------------------------------------------------------------------------------------------
135           Anna                   Gallagher               f                24.03.99          32
- -------------------------------------------------------------------------------------------------------------
136           Mary Kate              Coyle                   f                15.03.99          40
- -------------------------------------------------------------------------------------------------------------
137           Paddy                  Cox                     m                02.08.01          43
- -------------------------------------------------------------------------------------------------------------
139           Thomas P               Walsh                   m                14.07.99          47
- -------------------------------------------------------------------------------------------------------------
140           Joseph                 Irwin                   m                29.07.01          17
- -------------------------------------------------------------------------------------------------------------
141           Alice                  Walsh                   f                13.08.01          54
- -------------------------------------------------------------------------------------------------------------
142           Aine                   Fury                    f                28.08.01          27
- -------------------------------------------------------------------------------------------------------------
143           Elizabeth              Clarke                  f                06.06.00          24
- -------------------------------------------------------------------------------------------------------------
144           Jacinta                Mahady                  f                10.08.99          27
- -------------------------------------------------------------------------------------------------------------
146           Bert                   Carolan                 m                13.09.99          37
- -------------------------------------------------------------------------------------------------------------
147           Helen                  Doherty                 f                14.09.99          39
- -------------------------------------------------------------------------------------------------------------
148           Leonard                Moran (SPF)             m                03.09.01          41
- -------------------------------------------------------------------------------------------------------------
150           Ann Marie              Gallagher               f                08.11.99          24
- -------------------------------------------------------------------------------------------------------------
151           Shane                  Moyles                  m                01.11.99          29
- -------------------------------------------------------------------------------------------------------------
152           Kieran                 Anderson                m                03.09.01          30
- -------------------------------------------------------------------------------------------------------------
153           Damien                 Gallagher               m                13.12.99          23
- -------------------------------------------------------------------------------------------------------------
155           Eric Noel              O'Connor                m                05.09.01          31
- -------------------------------------------------------------------------------------------------------------
156           Thomas                 Canavan                 m                12.09.01          31
- -------------------------------------------------------------------------------------------------------------
158           Finnbar                Sullivan                m                17.01.00          27
- -------------------------------------------------------------------------------------------------------------
159           Orla                   Cunningham              f                31.07.00          23
- -------------------------------------------------------------------------------------------------------------
160           Gerard                 Adams                   m                27.01.00          28
- -------------------------------------------------------------------------------------------------------------
162           Martin Joseph          Healy                   m                14.02.00          32
- -------------------------------------------------------------------------------------------------------------
163           Katherine              Kennedy                 f                31.07.00          25
- -------------------------------------------------------------------------------------------------------------
164           Marion                 Barrett                 m                19.09.01          45
- -------------------------------------------------------------------------------------------------------------
165           Niamh                  O'Brien                 f                25.09.01          26
- -------------------------------------------------------------------------------------------------------------
167           Patricia               Barrett                 f                24.03.00          46
- -------------------------------------------------------------------------------------------------------------
169           Michael                Brannelly               m                30.10.01          34
- -------------------------------------------------------------------------------------------------------------
170           Louis                  Conlon                  m                12.11.01          22
- -------------------------------------------------------------------------------------------------------------
171           Margaret               Ruane                   f                12.11.01          56
- -------------------------------------------------------------------------------------------------------------
173           Michael                Doherty                 m                18.06.00          17
- -------------------------------------------------------------------------------------------------------------
175           Brian                  Murray                  m                26.11.01          30
- -------------------------------------------------------------------------------------------------------------
176           Yolanda                Garcia                  f                04.09.00          34
- -------------------------------------------------------------------------------------------------------------
180           Nathy                  Neary                   m                28.08.00          47
- -------------------------------------------------------------------------------------------------------------
182           Niall                  McAndrew                m                18.09.00          22
- -------------------------------------------------------------------------------------------------------------
186           Oliver                 Timlin                  m                02.10.00          31
- -------------------------------------------------------------------------------------------------------------
187           John                   Dermody                 m                02.10.00          32
- -------------------------------------------------------------------------------------------------------------


                                     -101-




- -------------------------------------------------------------------------------------------------------------
EMP. NO.      FIRST NAME             SURNAME                 GENDER           START DATE        AGE
- -------------------------------------------------------------------------------------------------------------
                                                                                 
188           Patricia               Gallagher               f                25.09.00          40
- -------------------------------------------------------------------------------------------------------------
192           Brian Martin           Langdon                 m                16.10.00          39
- -------------------------------------------------------------------------------------------------------------
199           Nuala                  Donoghue                f                20.11.00          27
- -------------------------------------------------------------------------------------------------------------
200           Anthony                Timoney                 m                21.11.00          39
- -------------------------------------------------------------------------------------------------------------
201           Lucia                  Rafter                  f                21.11.00          46
- -------------------------------------------------------------------------------------------------------------
203           Antoinette             Sweeney                 f                15.01.01          25
- -------------------------------------------------------------------------------------------------------------
205           Maureen                Gaughan                 f                29.01.01          21
- -------------------------------------------------------------------------------------------------------------
207           Noel                   Beattie                 m                26.02.01          20
- -------------------------------------------------------------------------------------------------------------
208           Mary Claire            Doherty                 f                12.03.01          19
- -------------------------------------------------------------------------------------------------------------


                                     -102-


                                 APPENDIX THREE

                        DETAILS OF PENSIONS (WARRANTY 10)

1.       Original Trust Deed dated 1st September, 1996 made by Biological
         Laboratories Europe Limited (the Principal Employer)

2.       New Ireland Assurance Group Retirement Plan Policy 0000805E

3.       New Ireland Assurance Group Life Assurance Policy 0000805E/L

4.       New Ireland Assurance Group Retirement Plan - "Important Information
         for all Policyholders"

5.       New Ireland Assurance Group Retirement Plan Annual Report 1997/1998

7.       List of all present members of Plan + age profile;

8.       Copy Letter from Revenue Commissioners approving the Plan as an "exempt
         approved scheme" under Part 30, Chapter 1, Taxes Consolidation Act,
         1997

                                     -103-


                                SEVENTH SCHEDULE

                              (SERVICE AGREEMENTS)

















                                     -104-


                                 EIGHTH SCHEDULE

                         IRREVOCABLE PROXY (CLAUSE 4.8)

__________ (the "Vendor") being the registered owner of __________ Ordinary
Shares of [euro 1] each (the "Shares") in __________ (the "Company") a company
incorporated under the laws of the Republic of Ireland hereby makes, constitutes
and appoints __________ the true and lawful attorney of the Vendor (with full
power to appoint a nominee to act in its place hereunder) from time to time to
exercise all voting and other rights attached to the Shares including but not
limited to, the rights of attending at, voting at, consenting to short notice
of, or requisitioning or joining in the requisition of any general, class, or
any other meeting of the members of the Company and without limitation to the
foregoing to exercise and enjoy other rights, privileges and powers whatsoever
attached to or in respect of the Shares and in each case with the same force and
effect as the Vendor might or could do, and the Vendor hereby ratifies and
confirms that all the said attorney or its nominee shall do or cause to be done
by virtue hereof.

This power and proxy is coupled with an interest and is irrevocable but shall
expire upon the registration in the register of members of the Company of
__________ or its nominee as owner of the Shares.

IN WITNESS whereof this irrevocable proxy has been executed as a Deed the day
and year herein contained.

Dated __________

SIGNED SEALED AND DELIVERED         )
by the said                                               )
in the presence of:-                                      )
                                                          )
                                                          )


                                     -105-


                                 NINTH SCHEDULE

                             ENVIRONMENTAL INDEMNITY















                                     -106-


                                 TENTH SCHEDULE

                                     PART A
                               MORAN PROPERTY MAP





















                                     -107-


                                 TENTH SCHEDULE

                                     PART B

                            SECOND MORAN PROPERTY MAP





















                                     -108-


SIGNED SEALED AND DELIVERED                 )
by the said LEONARD MORAN                   )
in the presence of:-                        )
                                            )
                                            )

SIGNED SEALED AND DELIVERED                 )
by the said CATHERINE CAULFIELD             )
in the presence of:-                        )
                                            )
                                            )

SIGNED SEALED AND DELIVERED                 )
by the said CATHERINE CAULFIELD             )
as the lawful attorney for ANNE CHANDLER    )
in the presence of:-                        )
                                            )
                                            )

SIGNED SEALED AND DELIVERED                 )
by the said WILLIAM DEREK TAVERNOR          )
in the presence of:-                        )
                                            )
                                            )

SIGNED SEALED AND DELIVERED                 )
by WILLIAM DEREK TAVERNOR                   )
as the lawful attorney for SUSAN TAVERNOR   )
in the presence of: -                       )
                                            )

SIGNED SEALED AND DELIVERED                 )
by WILLIAM DEREK TAVERNOR                   )
as the lawful attorney for ANGELA TAVERNOR  )
in the presence of: -                       )
                                            )

SIGNED SEALED AND DELIVERED                 )
by WILLIAM DEREK TAVERNOR                   )
as the lawful attorney for NICOLA TAVERNOR  )
in the presence of: -                       )
                                            )

                                     -109-


SIGNED SEALED AND DELIVERED                 )
by the said EUGENE CAULFIELD                )
in the presence of: -                       )
                                            )

SIGNED SEALED AND DELIVERED                 )
by CATHERINE CAULFILED                      )
as the lawful attorney for PADRAIG SOMERS   )
in the presence of: -                       )
                                            )

SIGNED SEALED AND DELIVERED                 )
by CATHERINE CAULFILED                      )
as the lawful attorney for EILEEN O'CONNOR  )
in the presence of: -                       )
                                            )

SIGNED SEALED AND DELIVERED                 )
by CATHERINE CAULFILED                      )
as the lawful attorney for MAUREEN RUANE    )
in the presence of: -                       )
                                            )

SIGNED SEALED AND DELIVERED                 )
by CATHERINE CAULFILED                      )
as the lawful attorney for MICHAEL O'BRIEN  )
in the presence of: -                       )
                                            )

SIGNED SEALED AND DELIVERED                 )
by CATHERINE CAULFILED                      )
as the lawful attorney for AILEEN CORCORAN  )
in the presence of: -                       )
                                            )

SIGNED SEALED AND DELIVERED                 )
by the said MARIA JOHNS                     )
in the presence of: -                       )
                                            )

                                     -110-


SIGNED SEALED AND DELIVERED                   )
by CATHERINE CAULFILED                        )
as the lawful attorney for JOAN O'MALLEY      )
in the presence of: -                         )
                                              )

SIGNED SEALED AND DELIVERED                   )
by CATHERINE CAULFILED                        )
as the lawful attorney for RICHARD CAULFIELD  )
in the presence of: -                         )
                                              )

SIGNED SEALED AND DELIVERED                   )
by the said FRANK DAVIS                       )
in the presence of: -                         )
                                              )

SIGNED SEALED AND DELIVERED                   )
by BRIAN WHITAKER                             )
as the lawful attorney for DESMOND BARRY      )
in the presence of: -                         )
                                              )

SIGNED SEALED AND DELIVERED                   )
by CATHERINE CAULFILED                        )
as the lawful attorney for TERRY MORONEY      )
in the presence of: -                         )
                                              )

SIGNED SEALED AND DELIVERED                   )
by the said MARGARET CONNOR                   )
in the presence of: -                         )
                                              )

SIGNED SEALED AND DELIVERED                   )
by WILLIAM DEREK TAVERNER                     )
as the lawful attorney for DAVID TAVERNOR     )
in the presence of: -                         )
                                              )

                                     -111-


SIGNED by                                     )
for and on behalf of                          )
CHARLES RIVER EUROPE GMBH                     )
in the presence of:-                          )
                                              )

SIGNED by                                     )
for and on behalf of                          )
CHARLES RIVER LABORATORIES INC                )
in the presence of:-                          )
                                              )






                                     -112-


                                   ANNEXURE A

MEMORANDUM AND ARTICLES OF ASSOCIATION OF:-

BIOLOGICAL LABORATORIES EUROPE LIMITED;

ENTOMOLOGY EUROPE LIMITED;

SAOTHARLANNA BITHEOLAIOCHA IDIRNAISUINTA TEORANTA











                                     -113-


                                   ANNEXURE B

         AUDITED CONSOLIDATED ACCOUNTS OF BIOLOGICAL LABORATORIES EUROPE
                          LIMITED AT 31 JANUARY, 2002




















                                     -114-


                                   ANNEXURE C

                     BIOLOGICAL LABORATORIES EUROPE LIMITED

- -------------------------------------------------------------------------------

Notes to the Consolidated financial Statements for the year ended 31 January,
2002

- -------------------------------------------------------------------------------

1        ACCOUNTING POLICIES

1.1      ACCOUNTING CONVENTION

         The financial statements are prepared in accordance with generally
         accepted accounting principles under the historical cost convention
         which comply with financial reporting standards of the Accounting
         Standards Board.

1.2      GOODWILL

         Acquired goodwill is written off in equal annual instalments over its
         estimated useful economic life of 10 years.

1.3      DEPRECIATION OF TANGIBLE FIXED ASSETS

         Provision is made for depreciation on all tangible assets at rates
         calculated to write off the cost or valuation, less estimated residual
         value, of each asset over its expected useful life and to the periods
         intended to benefit from their use as follows:-


                                                  
         Land and buildings                 -        2% Straight Line
         Equipment, Fixtures & Fittings     -        15% Reducing Balance
         Fixtures, fittings and equipment   -        15% Reducing Balance
         Motor vehicles                     -        20% Reducing Balance
         Office Equipment                   -        15% Reducing Balance


1.4      STOCK

         Stock is valued at the lower of cost and net realisable value. Cost
         comprises expenditure directly incurred in purchasing stocks. Net
         realisable value represents the estimated selling price less further
         costs expected to be incurred to disposal. No value is attributed to
         animal stocks bred in-house by the company.

1.5      FOREIGN CURRENCIES

         The financial statements are expressed in Irish Pounds (IR(pound)).
         Transactions in foreign currencies have been translated at the average
         rate of exchange for the year. Monetary assets and liabilities
         denominated in foreign currencies are translated at the rate ruling at
         the balance sheet date. Foreign exchange gains /losses arise primarily
         on sterling transactions and are dealt with through the Profit & Loss
         Account.

1.6      TAXATION

         The charge for taxation is based on the profits on ordinary activities
         for the year at the manufacturing rate of 10%.

                                     -115-


1.7      GOVERNMENT GRANTS

         REVENUE GRANTS

         Revenue grants are credited to the profit and loss account of the
         period to which they relate. Any revenue grants received which are
         repayable are treated as deferred income in the accounts under note 24.

         CAPITAL GRANTS

         Capital grants once approved are included in the accounts of the period
         in which the capital expenditure occurred. Such grants are released to
         revenue over the period of the grant agreement to match the
         depreciation of the relevant capital asset.

1.8      LEASING AND HIRE PURCHASE COMMITMENTS

         Tangible fixed assets acquired under finance lease arrangements are
         capitalised at cost and are depreciated over their useful lives. The
         capital element of the related rental obligations is included in
         creditors and the interest element of the finance lease rentals is
         charged to the profit and loss account in such a manner as to give a
         constant rate of charge over a period of the lease.

         Operating lease rentals are charged to the profit and loss account as
         they are incurred.

1.9      TURNOVER

         Turnover comprises the invoice value of goods and services supplied by
         the Company, exclusive of Value Added Tax.

1.10     PENSIONS

         The Company made payments to a defined contribution pension fund on
         behalf of certain employees. Contributions are charged to the profit
         and loss account in the year in which they fall due.

1.11     TAXATION

         Full provision in respect of deferred taxation is made for all timing
         differences that have originated but not reversed by the balance sheet
         date. Deferred taxation is not recognised on permanent differences.

                                     -116-