EXHIBIT 12
 
                      PFIZER INC. AND SUBSIDIARY COMPANIES
               COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES
 


                                                                           YEAR ENDED DECEMBER 31,
                                                              --------------------------------------------------
                                                                1995       1994      1993      1992       1991
                                                              --------   --------   ------   --------   --------
                                                                     (MILLIONS OF DOLLARS, EXCEPT RATIOS)
                                                                                         
Determination of Earnings:
  Income from continuing operations before provision for
   taxes on income, minority interests and cumulative effect
   of accounting changes....................................  $2,299.2   $1,830.5   $835.3   $1,541.0   $  913.2
  Less:
    Minority interests......................................       7.0        4.6      2.6        2.7        3.2
    Undistributed earnings/(losses) of unconsolidated
     subsidiaries...........................................      (0.3)      (0.7)     0.7        8.5        0.8
                                                              --------   --------   ------   --------   --------
  Adjusted income...........................................   2,292.5    1,826.6    832.0    1,529.8      909.2
    Fixed charges...........................................     231.9      158.4    135.6      130.1      155.2
                                                              --------   --------   ------   --------   --------
      Total earnings as defined.............................  $2,524.4   $1,985.0   $967.6   $1,659.9   $1,064.4
                                                              --------   --------   ------   --------   --------
                                                              --------   --------   ------   --------   --------
Fixed charges
  Interest expense (a)......................................  $  192.5   $  126.9   $106.5   $  103.4   $  130.1
  Rents (b).................................................      39.4       31.5     29.1       26.7       25.1
                                                              --------   --------   ------   --------   --------
    Fixed charges...........................................     231.9      158.4    135.6      130.1      155.2
  Capitalized interest......................................      12.4       14.7     14.0       12.2        8.0
                                                              --------   --------   ------   --------   --------
    Total fixed charges.....................................  $  244.3   $  173.1   $149.6   $  142.3   $  163.2
                                                              --------   --------   ------   --------   --------
                                                              --------   --------   ------   --------   --------
Ratio of earnings to fixed charges..........................      10.3       11.5      6.5       11.7        6.5
                                                              --------   --------   ------   --------   --------
                                                              --------   --------   ------   --------   --------

 
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(a) Interest expense includes amortization of debt discount and expenses.
 
(b) Rents  included in the  computation consist of  one-third of rental expense,
    which the Company  believes to  be a  conservative estimate  of an  interest
    factor in its leases, which are not material.
 
Note:  In  December 1995, the  Company agreed to sell  substantially all the net
       assets of  the food  science  business. As  a  result, the  food  science
       business  has been  reported as  a discontinued  operation. The  sale was
       completed in January 1996. The computations  of the ratio of earnings  to
       fixed  charges  for the  years 1991  through 1994  have been  restated to
       remove the income from operations of the Company's food science business.