- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
 
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
 
                            ------------------------
 
                                   FORM 11-K
 
             FOR ANNUAL REPORTS OF EMPLOYEE STOCK PURCHASE, SAVINGS
                 AND SIMILAR PLANS PURSUANT TO SECTION 15(d) OF
                      THE SECURITIES EXCHANGE ACT OF 1934
 
(MARK ONE)
/X/  ANNUAL  REPORT PURSUANT TO SECTION 15(d)  OF THE SECURITIES EXCHANGE ACT OF
     1934 (FEE REQUIRED)
 
                  For the fiscal year ended December 31, 1995
 
                                       OR
 
/ /  TRANSITION REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE  ACT
     OF 1934 (NO FEE REQUIRED)
 
                   For the transition period from ... to ...
                         Commission file number 1-3619
 
A.  FULL  TITLE OF THE PLAN AND THE ADDRESS  OF THE PLAN, IF DIFFERENT FROM THAT
    OF THE ISSUER NAMED BELOW:
 
                       PFIZER SAVINGS AND INVESTMENT PLAN
                     FOR EMPLOYEES RESIDENT IN PUERTO RICO
 
B.  NAME OF ISSUER OF THE SECURITIES HELD  PURSUANT TO THE PLAN AND THE  ADDRESS
    OF ITS PRINCIPAL EXECUTIVE OFFICES:
 
                                  PFIZER INC.
                              235 EAST 42ND STREET
                            NEW YORK, NEW YORK 10017
 
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- --------------------------------------------------------------------------------

                       PFIZER SAVINGS AND INVESTMENT PLAN
                     FOR EMPLOYEES RESIDENT IN PUERTO RICO
 
                            STATEMENT OF NET ASSETS
                          AVAILABLE FOR PLAN BENEFITS
 
                               DECEMBER 31, 1995
 


                                                               NON-PARTICIPANT
                                                                  DIRECTED
                                                               --------------
                                                                PFIZER INC.              PARTICIPANT DIRECTED
                                                                COMMON STOCK   -----------------------------------------
                                                   TOTAL            FUND          FUND A        FUND B        FUND C
                                               --------------  --------------  -------------  -----------  -------------
                                                                                            
                   ASSETS
- ---------------------------------------------
 
Investments, at fair value:
  Pfizer Inc. common stock:
    Pfizer Inc. Common Stock Fund, 87,517
     shares, cost $2,596,932; Fund C, 71,818
     shares; cost $2,271,405.................  $   10,037,703   $  5,513,160   $          --  $        --  $   4,524,543
  Other marketable securities: Fund A, cost
   $1,806,318; Fund B, cost $278,353.........       2,292,532             --       1,876,876      415,656             --
Interest-bearing deposits, at cost which
 approximates fair value.....................         210,494         57,834         115,476       13,387         23,797
                                               --------------  --------------  -------------  -----------  -------------
      Total investments......................      12,540,729      5,570,994       1,992,352      429,043      4,548,340
 
Interest receivable..........................          32,630            155          32,379           34             62
 
Contributions receivable:
  Employees..................................         300,316             --         103,983       13,772        182,561
  Employers..................................         157,502        157,502              --           --             --
                                               --------------  --------------  -------------  -----------  -------------
    Net assets available for plan benefits --
     Note 8..................................  $   13,031,177   $  5,728,651   $   2,128,714  $   442,849  $   4,730,963
                                               --------------  --------------  -------------  -----------  -------------
                                               --------------  --------------  -------------  -----------  -------------
Number of units outstanding at end of year...                      1,461,391       1,438,320      231,858      1,238,472
 
Unit value...................................                          $3.92           $1.48        $1.91          $3.82

 
See Notes to Financial Statements which are an integral part of these financial
                                  statements.
 
                                       1

                       PFIZER SAVINGS AND INVESTMENT PLAN
                     FOR EMPLOYEES RESIDENT IN PUERTO RICO
 
                            STATEMENT OF NET ASSETS
                          AVAILABLE FOR PLAN BENEFITS
 
                               DECEMBER 31, 1994
 


                                                               NON-PARTICIPANT
                                                                  DIRECTED
                                                               --------------
                                                                PFIZER INC.              PARTICIPANT DIRECTED
                                                                COMMON STOCK   -----------------------------------------
                                                    TOTAL           FUND          FUND A        FUND B        FUND C
                                                -------------  --------------  -------------  -----------  -------------
                                                                                            
                    ASSETS
- ----------------------------------------------
 
Investments, at fair value:
  Pfizer Inc. common stock:
    Pfizer Inc. Common Stock Fund, 76,414
     shares, cost $2,059,026; Fund C, 67,854
     shares, cost $2,056,665..................  $   5,572,351   $  2,951,523   $          --  $        --  $   2,620,828
  Other marketable securities: Fund A, cost
   $1,428,837; Fund B, cost $230,455..........      1,634,171             --       1,369,619      264,552             --
Interest-bearing deposits, at cost which
 approximates fair value......................        159,799         47,863         107,407        4,529             --
                                                -------------  --------------  -------------  -----------  -------------
      Total investments.......................      7,366,321      2,999,386       1,477,026      269,081      2,620,828
 
Interest receivable...........................         28,067            212          27,721           16            118
 
Contributions receivable:
  Employees...................................        240,606             --          91,543       12,747        136,316
  Employers...................................        131,149        131,149              --           --             --
                                                -------------  --------------  -------------  -----------  -------------
  Net assets available for plan benefits --
   Note 8.....................................  $   7,766,143   $  3,130,747   $   1,596,290  $   281,844  $   2,757,262
                                                -------------  --------------  -------------  -----------  -------------
                                                -------------  --------------  -------------  -----------  -------------
 
Number of units outstanding at end of year....                     1,297,807       1,233,674      199,889      1,174,996
 
Unit value....................................                         $2.41           $1.29        $1.41          $2.35

 
See Notes to Financial Statements which are an integral part of these financial
                                  statements.
 
                                       2

                       PFIZER SAVINGS AND INVESTMENT PLAN
                     FOR EMPLOYEES RESIDENT IN PUERTO RICO
 
                       STATEMENT OF CHANGES IN NET ASSETS
                          AVAILABLE FOR PLAN BENEFITS
 
                          YEAR ENDED DECEMBER 31, 1995
 


                                                               NON-PARTICIPANT
                                                                  DIRECTED
                                                               --------------
                                                                PFIZER INC.              PARTICIPANT DIRECTED
                                                                COMMON STOCK   -----------------------------------------
                                                   TOTAL            FUND          FUND A        FUND B        FUND C
                                               --------------  --------------  -------------  -----------  -------------
                                                                                            
Net investment income:
  Cash Dividends:
    Pfizer Inc. common stock.................  $      159,945   $     86,696   $          --  $        --  $      73,249
    Other marketable securities..............           4,898             --              --        4,898             --
  Interest...................................         129,556          3,825         119,267        4,196          2,268
                                               --------------  --------------  -------------  -----------  -------------
                                                      294,399         90,521         119,267        9,094         75,517
 
Investment management fees -- Note 4.........          (5,129)            --              --       (5,129)            --
                                               --------------  --------------  -------------  -----------  -------------
                                                      289,270         90,521         119,267        3,965         75,517
 
Realized gain on investments, net -- Note 5:
  Pfizer Inc. common stock...................          60,220         29,373              --           --         30,847
  Other marketable securities................           5,614             --             156        5,458             --
                                               --------------  --------------  -------------  -----------  -------------
                                                       65,834         29,373             156        5,458         30,847
                                               --------------  --------------  -------------  -----------  -------------
 
Unrealized appreciation of investments, net
 -- Note 6...................................       3,945,688      2,023,731         129,776      103,206      1,688,975
                                               --------------  --------------  -------------  -----------  -------------
                                                    4,300,792      2,143,625         249,199      112,629      1,795,339
                                               --------------  --------------  -------------  -----------  -------------
Contributions -- Note 7:
  Employees..................................       2,340,054             --         846,905      136,407      1,356,742
  Employers..................................       1,231,787      1,231,787              --           --             --
Withdrawals -- Note 8........................      (2,607,599)      (788,809)       (526,514)     (77,333)    (1,214,943)
Transfers between funds -- net...............              --         11,301         (37,166)     (10,698)        36,563
                                               --------------  --------------  -------------  -----------  -------------
                                                      964,242        454,279         283,225       48,376        178,362
                                               --------------  --------------  -------------  -----------  -------------
Net increase.................................       5,265,034      2,597,904         532,424      161,005      1,973,701
Net assets available for plan benefits --
 Note 8:
  Beginning of year..........................       7,766,143      3,130,747       1,596,290      281,844      2,757,262
                                               --------------  --------------  -------------  -----------  -------------
  End of year................................  $   13,031,177   $  5,728,651   $   2,128,714  $   442,849  $   4,730,963
                                               --------------  --------------  -------------  -----------  -------------
                                               --------------  --------------  -------------  -----------  -------------

 
See Notes to Financial Statements which are an integral part of these financial
                                  statements.
 
                                       3

                       PFIZER SAVINGS AND INVESTMENT PLAN
                     FOR EMPLOYEES RESIDENT IN PUERTO RICO
 
                       STATEMENT OF CHANGES IN NET ASSETS
                          AVAILABLE FOR PLAN BENEFITS
 
                          YEAR ENDED DECEMBER 31, 1994
 


                                                               NON-PARTICIPANT
                                                                  DIRECTED
                                                               --------------
                                                                PFIZER INC.              PARTICIPANT DIRECTED
                                                                COMMON STOCK   -----------------------------------------
                                                   TOTAL            FUND          FUND A        FUND B        FUND C
                                               --------------  --------------  -------------  -----------  -------------
                                                                                            
Net investment income:
  Cash Dividends:
    Pfizer Inc. common stock.................  $      126,512   $     66,877   $          --  $        --  $      59,635
    Other marketable securities..............           6,102             --              --        6,102             --
  Interest...................................          84,462          1,803          80,710          295          1,654
                                               --------------  --------------  -------------  -----------  -------------
                                                      217,076         68,680          80,710        6,397         61,289
 
Investment management fees -- Note 4.........          (1,026)            --              --       (1,026)            --
                                               --------------  --------------  -------------  -----------  -------------
                                                      216,050         68,680          80,710        5,371         61,289
Realized gains on other marketable
 securities, net -- Note 5...................           1,356             --              --        1,356             --
Unrealized appreciation (depreciation) of
 investments, net -- Note 6..................         576,161        350,942         (81,819)     (10,308)       317,346
                                               --------------  --------------  -------------  -----------  -------------
                                                      793,567        419,622          (1,109)      (3,581)       378,635
                                               --------------  --------------  -------------  -----------  -------------
Contributions -- Note 7:
  Employees..................................       2,068,551             --         789,189      130,285      1,149,077
  Employers..................................       1,093,036      1,093,036              --           --             --
Withdrawals -- Note 8........................      (1,998,601)      (716,082)       (399,980)     (89,122)      (793,417)
Transfers between funds -- net...............              --            765          37,973       (1,059)       (37,679)
                                               --------------  --------------  -------------  -----------  -------------
                                                    1,162,986        377,719         427,182       40,104        317,981
                                               --------------  --------------  -------------  -----------  -------------
Net increase.................................       1,956,553        797,341         426,073       36,523        696,616
Net assets available for plan benefits --
 Note 8:
  Beginning of year..........................       5,809,590      2,333,406       1,170,217      245,321      2,060,646
                                               --------------  --------------  -------------  -----------  -------------
  End of year................................  $    7,766,143   $  3,130,747   $   1,596,290  $   281,844  $   2,757,262
                                               --------------  --------------  -------------  -----------  -------------
                                               --------------  --------------  -------------  -----------  -------------

 
See Notes to Financial Statements which are an integral part of these financial
                                  statements.
 
                                       4

                     PFIZER SAVINGS AND INVESTMENT PLAN FOR
                       EMPLOYEES RESIDENT IN PUERTO RICO
                         NOTES TO FINANCIAL STATEMENTS
                           DECEMBER 31, 1995 AND 1994
 
NOTE 1 -- SUMMARY PLAN DESCRIPTION
 
    GENERAL  -- The Pfizer Savings and Investment Plan for Employees Resident in
Puerto Rico  (the "Plan")  is  a defined  contribution  savings plan  which  was
adopted  on February 1, 1990. Participation in  the Plan is open to all eligible
employees of  the  Puerto  Rico  branches of  Pfizer  Pharmaceuticals,  Inc.,  a
subsidiary  of  Pfizer Inc.,  and Pfizer  Corporation, an  indirect wholly-owned
subsidiary of Pfizer Inc., (individually and collectively, the "Companies"). The
Plan is subject to the provisions of the Employee Retirement Income Security Act
of 1974.
 
    The following is a  general description of certain  provisions of the  Plan.
Refer to the Plan for a complete description of the Plan.
 
    CONTRIBUTIONS  -- Each  participant may  make contributions  on an after-tax
basis or  on  a  before-tax  basis  (that  is,  choose  to  reduce  his  or  her
compensation  and have the  Companies contribute on  his or her  behalf), or may
contribute on a basis combining the two. Before-tax contributions are subject to
certain restrictions for employees who  are considered highly compensated  under
Section  165(e)  of  the  Puerto  Rico  Income  Tax  Act  of  1954,  as amended.
Contributions of up to 2% of compensation are matched 100% by the Companies  and
the  next 4%  is matched  50%. Employee  contributions in  excess of  6% are not
matched.
 
    INVESTMENT OPTIONS -- Each participant in the Plan elects to have his or her
contributions invested in  any one or  any combination of  the three  investment
funds. These funds are described below:
 
        Fund A -- Fixed income
 
        Fund B -- An index fund of corporate common stocks
 
        Fund C -- Common stock of Pfizer Inc.
 
    At  December  31,  1995  and  1994,  there  were  1,015  and  970 employees,
respectively, participating in the  Plan, some of whom  had investments in  more
than  one employee investment fund. On the basis of allocations by the employees
of their contributions at December 31,  1995 and 1994, respectively, Fund A  had
566  and 518 participating  employees, Fund B, 160  and 152 and  Fund C, 763 and
678.
 
    All matching contributions  are invested  by the  Trustee in  a fourth  fund
designated  the "Pfizer Inc. Common Stock Fund," which consists solely of common
stock of Pfizer Inc. These contributions are non-participant directed.
 
    The Plan's trust  agreement provides that  any portion of  any of the  funds
may, pending its permanent investment or distribution, be invested in short-term
investments.
 
    ELIGIBILITY AND VESTING -- Substantially all the employees of the Companies,
who  are  resident in  Puerto  Rico, are  eligible  to participate  in  the Plan
beginning on the  first January  1 following their  date of  employment, or  the
beginning  of any  month or payroll  period thereafter. A  member is immediately
vested in the full value of his or her accounts (i.e., participant and  employer
contributions) in Funds A, B and C and the Pfizer Inc. Common Stock Fund.
 
    PAYMENT  OF BENEFITS -- Upon separation from service, retirement, disability
or death, a participant may elect to  receive either a lump-sum amount equal  to
the  value of the  participant's account, or annual  installments subject to the
provisions of  the Plan.  For termination  of service  due to  other reasons,  a
participant  may  receive  the  value  of  his  or  her  account  as  a lump-sum
distribution.
 
                                       5

                     PFIZER SAVINGS AND INVESTMENT PLAN FOR
                       EMPLOYEES RESIDENT IN PUERTO RICO
                         NOTES TO FINANCIAL STATEMENTS
                           DECEMBER 31, 1995 AND 1994
 
NOTE 1 -- SUMMARY PLAN DESCRIPTION (CONTINUED)
    WITHDRAWALS  --  A  participant  in  the  Plan  may  make  full  or  partial
withdrawals of funds subject to the provisions of the Plan.
 
    TERMINATION  -- The Companies expect to  continue the Plan indefinitely, but
necessarily reserve the right to amend, suspend or discontinue it in whole or in
part, at  any  time, by  action  of the  Companies'  Boards of  Directors.  Upon
termination  of the  Plan, each member  affected thereby shall  receive the full
value of his or her share in Fund A, B and C and his or her share in the Company
Common Stock  Fund as  though he  or she  had retired  as of  the date  of  such
termination.  No part of the assets  in the investment fund established pursuant
to the Plan will at any time revert to the Companies.
 
NOTE 2 -- SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
 
    BASIS OF ACCOUNTING -- The financial statements of the Plan are prepared  on
the accrual basis of accounting. For treatment of benefits payable refer to Note
8.
 
    INVESTMENT  VALUATION -- Pfizer  Inc. common stock is  valued at the closing
market price on the last business  day of the year. Other marketable  securities
are  valued at fair value  based on the closing market  price of the security on
the last business day of  the year except for investments  in the index fund  of
corporate  common stocks, which are recorded at  fair value based on the closing
market price of  the underlying  investments held  by the  fund as  of the  last
business  day of the year. Interest-bearing deposits are recorded at cost, which
approximates fair value.
 
    SECURITY TRANSACTIONS -- Purchases and sales of securities are reflected  on
a  trade-date basis. Realized gains and losses on sales of investments represent
the difference between the net proceeds received and the cost of the investments
(average cost if less than the entire investment is sold).
 
    UNREALIZED  APPRECIATION   (DEPRECIATION)  OF   INVESTMENTS  --   Unrealized
appreciation (depreciation) of investments represents the difference between the
cost of the investments and the fair value at the end of the year. Additionally,
it includes the reversal of the unrealized appreciation (depreciation) as of the
end of the prior year.
 
    DIVIDEND RECOGNITION -- Dividend income is recorded on the ex-dividend date.
Income from other investments is recorded as earned.
 
    PFIZER INC. COMMON STOCK -- In June 1995, Pfizer Inc. effected a two-for-one
stock split in the form of a 100% stock dividend. The number of shares of Pfizer
Inc.  common stock held by  the Plan as of December  31, 1994 (Pfizer Inc. Stock
Fund and Fund C) have been restated to reflect the stock split.
 
NOTE 3 -- INCOME TAXES
    No provision has been  made for Puerto  Rico income tax  in reliance upon  a
determination  letter issued  by the Puerto  Rico Department  of Treasury, which
states that the Plan meets the requirements of Section 165(a) of the Puerto Rico
Income Tax Act of 1954 and that the trust established thereunder is entitled  to
exemption.
 
    All  contributions made to  the Plan by  the Companies, including before-tax
contributions  made  on  the  employee's   behalf  by  the  Companies  and   the
appreciation  on all  funds in  the employee's  account are  not taxable  to the
employee under Puerto  Rico income  tax law while  these amounts  remain in  the
Plan.
 
                                       6

                     PFIZER SAVINGS AND INVESTMENT PLAN FOR
                       EMPLOYEES RESIDENT IN PUERTO RICO
                         NOTES TO FINANCIAL STATEMENTS
                           DECEMBER 31, 1995 AND 1994
 
NOTE 4 -- ADMINISTRATIVE COSTS
    Except  for  certain  investment management  fees  (Fund B),  all  costs and
expenses of administering the Plan were borne by the Companies.
 
NOTE 5 -- REALIZED GAINS ON INVESTMENTS
    The aggregate net proceeds and carrying value used in the calculation of the
realized gains on investments are as follows:
 


                                                             NET                    REALIZED
                                                          PROCEEDS       COST         GAINS
                                                         -----------  -----------  -----------
                                                                          
Pfizer Inc. Common Stock:
  1995.................................................  $   183,217  $   122,997  $    60,220
Other Marketable Securities:
  1995.................................................       65,012       59,398        5,614
  1994.................................................      116,380      115,024        1,356

 
NOTE 6 -- UNREALIZED APPRECIATION (DEPRECIATION) OF INVESTMENTS
 
    The change in the  amount of unrealized  appreciation (depreciation) was  as
follows:


                                                      AGGREGATE UNREALIZED
                                                  ----------------------------
                                                  DECEMBER 31,   DECEMBER 31,   CHANGE DURING
                                                      1995           1994            1995
                                                  -------------  -------------  --------------
                                                                       
Pfizer Inc. Common Stock Fund...................  $   2,916,228  $     892,497   $  2,023,731
Fund A..........................................         70,558        (59,218)       129,776
Fund B..........................................        137,303         34,097        103,206
Fund C..........................................      2,253,138        564,163      1,688,975
                                                  -------------  -------------  --------------
                                                  $   5,377,227  $   1,431,539   $  3,945,688
                                                  -------------  -------------  --------------
                                                  -------------  -------------  --------------
 

 
                                                      AGGREGATE UNREALIZED
                                                  ----------------------------
                                                  DECEMBER 31,   DECEMBER 31,   CHANGE DURING
                                                      1994           1993            1994
                                                  -------------  -------------  --------------
                                                                       
Pfizer Inc. Common Stock Fund...................  $     892,497  $     541,555   $    350,942
Fund A..........................................        (59,218)        22,601        (81,819)
Fund B..........................................         34,097         44,405        (10,308)
Fund C..........................................        564,163        246,817        317,346
                                                  -------------  -------------  --------------
                                                  $   1,431,539  $     855,378   $    576,161
                                                  -------------  -------------  --------------
                                                  -------------  -------------  --------------

 
                                       7

                     PFIZER SAVINGS AND INVESTMENT PLAN FOR
                       EMPLOYEES RESIDENT IN PUERTO RICO
                         NOTES TO FINANCIAL STATEMENTS
                           DECEMBER 31, 1995 AND 1994
 
NOTE 7 -- CONTRIBUTIONS
 
    The  participating employees  and their employers  contributed the following
amounts to the Plan:


1995                                                 EMPLOYEES      EMPLOYERS        TOTAL
                                                   -------------  -------------  -------------
                                                                        
Pfizer Pharmaceuticals, Inc.
 (Puerto Rico Branch)............................  $   1,947,066  $   1,024,059  $   2,971,125
Pfizer Corporation
 (Puerto Rico Branch)............................        392,988        207,728        600,716
                                                   -------------  -------------  -------------
                                                   $   2,340,054  $   1,231,787  $   3,571,841
                                                   -------------  -------------  -------------
                                                   -------------  -------------  -------------
 

 
1994
                                                                        
Pfizer Pharmaceuticals, Inc.
 (Puerto Rico Branch)............................  $   1,669,542  $     904,692  $   2,574,234
Pfizer Corporation
 (Puerto Rico Branch)............................        399,009        188,344        587,353
                                                   -------------  -------------  -------------
                                                   $   2,068,551  $   1,093,036  $   3,161,587
                                                   -------------  -------------  -------------
                                                   -------------  -------------  -------------

 
NOTE 8 -- WITHDRAWALS AND RECONCILIATION WITH FORM 5500
    For financial statement purposes, participant withdrawals and  distributions
are  recorded when  paid rather  than when  processed and  approved for payment.
Therefore, the net assets  available for Plan benefits  as of December 31,  1995
and  1994  do not  reflect a  reduction  for the  following benefits  payable to
participants who had requested withdrawals as of December 31, but which were not
distributed until the subsequent year:
 


                                                                         1995         1994
                                                                      -----------  -----------
                                                                             
Pfizer Inc. Common Stock Fund.......................................  $    62,751  $    68,397
Fund A..............................................................       27,423       30,505
Fund B..............................................................        3,822        4,929
Fund C..............................................................       89,894      104,993
                                                                      -----------  -----------
                                                                      $   183,890  $   208,824
                                                                      -----------  -----------
                                                                      -----------  -----------

 
    For the  purposes  of Form  5500,  such withdrawals  and  distributions  are
recorded when processed and approved for payment. Therefore, benefits payable to
participants  who  have  requested  withdrawals have  been  reported  as benefit
expense within Form 5500 for those years.
 
                                       8

                       PFIZER SAVINGS AND INVESTMENT PLAN
                     FOR EMPLOYEES RESIDENT IN PUERTO RICO
                            ITEM 27A -- SCHEDULE OF
                      ASSETS HELD FOR INVESTMENT PURPOSES
                               DECEMBER 31, 1995
FUND A:
 


                                                        INTEREST RATE    MATURITY       COST        FAIR VALUE
                                                        --------------  ----------  -------------  -------------
                                                                                       
OTHER MARKETABLE SECURITIES:
- ------------------------------------------------------
U.S. GOVERNMENT SECURITIES
- ------------------------------------------------------
U.S. Treasury Notes...................................          7.87%     08/15/01  $     111,035  $     123,974
U.S. Treasury Notes...................................          6.87      10/31/96         50,594         50,641
                                                                                    -------------  -------------
                                                                                          161,629        174,615
                                                                                    -------------  -------------
OTHER MARKETABLE SECURITIES
- ------------------------------------------------------
Federal Home Loan Bank................................          9.15      03/25/97         43,168         43,857
Federal Home Loan Bank Medium Term
 Note.................................................          6.97      11/20/97         75,000         77,156
Federal National Mortgage Association.................          8.80      07/25/97         49,406         52,617
Federal National Mortgage Association.................          7.85      09/10/98         25,969         26,516
Federal National Mortgage Association.................          5.74      02/12/98         71,050         70,041
Federal Farm Credit Bank Bond.........................          6.05      04/21/03         29,822         30,520
Federal Home Loan Mortgage Corporation................          6.35      03/07/01         26,758         27,943
Federal National Mortgage Association Term Note.......          7.90      04/10/02         44,944         46,371
Federal National Mortgage Association Term Note.......          6.95      09/10/02         44,788         45,710
Federal National Mortgaage Association Term Note......          5.80      12/10/03          8,938          9,934
SLMA Medium Term Note.................................          5.50      07/08/02         57,213         59,325
Federal Home Loan Mortgage Term Note..................          7.03      10/19/96         60,355         61,472
Federal National Mortgage Association.................          7.05      10/10/96         25,813         25,297
                                                                                    -------------  -------------
                                                                                          563,224        576,759
                                                                                    -------------  -------------
CORPORATE DEBENTURES
- ------------------------------------------------------
World Bank Medium Term Note...........................          9.19      06/23/98         42,807         43,411
Tennessee Valley Authority............................     zero coupon    07/15/03         87,554         97,970
Tennessee Valley Authority............................          6.12      07/15/03         76,641         75,140
Tennessee Valley Authority............................          6.37      06/15/05        117,188        124,124
Citicorp..............................................          9.00      04/15/99         51,213         54,820
Dean Witter Discover Bond.............................          6.25      03/15/00         22,810         24,358
Exxon Bond............................................          7.87      08/15/97         57,520         57,063
Lehman Brothers Holdings, Inc. Note...................          8.37      04/01/97        100,409        102,969
Merrill Lynch.........................................          6.37      03/30/99         31,920         32,525
Shell Oil Co. Bond....................................          6.95      12/15/98         50,406         52,002
AT&T Corporate Bond...................................          6.75      04/01/04         50,677         52,250
New Jersey Bell Corporate Bond........................          5.87      02/01/04         39,048         39,662
Bell South Telephone..................................          6.37      06/15/04         40,000         40,900
Dean Witter, Discover & Co............................          6.87      03/01/03         25,499         28,094
General Telephone Co. Florida.........................          8.00      03/01/01         39,684         40,584
Georgia Power First Mortgage Bond.....................          6.62      04/01/03         29,888         30,548
IBM Corporate Bond....................................          7.25      11/01/02         29,738         32,100
Merrill Lynch Corporate Bond..........................          6.25      10/15/08         22,906         26,476
 
                                                                                                     (CONTINUED)

 
                                       9

                       PFIZER SAVINGS AND INVESTMENT PLAN
                     FOR EMPLOYEES RESIDENT IN PUERTO RICO
                            ITEM 27A -- SCHEDULE OF
                      ASSETS HELD FOR INVESTMENT PURPOSES
                                  (CONTINUED)
                               DECEMBER 31, 1995


                                                        INTEREST RATE    MATURITY       COST        FAIR VALUE
                                                        --------------  ----------  -------------  -------------
                                                                                       
New Jersey Bell Telephone.............................          7.25%     06/01/02  $       9,882  $      10,707
Wal-Mart Stores.......................................          6.75      05/15/02         90,675         93,867
General Electric Credit Corporation...................          7.46      09/30/96         40,000         40,590
General Electric Credit Corporation...................          6.94      11/22/96         25,000         25,342
                                                                                    -------------  -------------
                                                                                        1,081,465      1,125,502
                                                                                    -------------  -------------
  Total other marketable securities...................                                  1,806,318      1,876,876
 
INTEREST-BEARING DEPOSIT
- ------------------------------------------------------
Banco Popular de Puerto Rico, Time Deposit............          4.62                      115,476        115,476
                                                                                    -------------  -------------
      Total of Fund A.................................                              $   1,921,794  $   1,992,352
                                                                                    -------------  -------------
                                                                                    -------------  -------------

 
FUND B:
 


                                                              NUMBER OF      INTEREST
               OTHER MARKETABLE SECURITIES                 SHARES OR UNITS     RATE          COST        FAIR VALUE
- ---------------------------------------------------------  ---------------  -----------  -------------  -------------
                                                                                            
The Northern Trust Company, Collective Stock Index
 Fund....................................................         7,844             --   $     278,353  $     415,656
 
INTEREST-BEARING DEPOSITS
- ---------------------------------------------------------
The Northern Trust Company, Short-Term Investment Fund...            --           5.64%         13,387         13,387
                                                                                         -------------  -------------
      Total of Fund B....................................                                $     291,740  $     429,043
                                                                                         -------------  -------------
                                                                                         -------------  -------------
FUND C:
 
Pfizer Inc. Common Stock.................................        71,818             --   $   2,271,405  $   4,524,543
 
INTEREST-BEARING DEPOSIT
- ---------------------------------------------------------
Banco Popular de Puerto Rico, Time Deposit...............            --           4.62          23,797         23,797
                                                                                         -------------  -------------
      Total of Fund C....................................                                $   2,295,202  $   4,548,340
                                                                                         -------------  -------------
                                                                                         -------------  -------------
COMPANY COMMON STOCK FUND:
Pfizer Inc. Common Stock.................................        87,517             --   $   2,596,932  $   5,513,160
 
INTEREST-BEARING DEPOSIT
- ---------------------------------------------------------
Banco Popular de Puerto Rico, Time Deposit...............            --           4.62          57,834         57,834
                                                                                         -------------  -------------
      Total Company Common Stock Fund....................                                $   2,654,766  $   5,570,994
                                                                                         -------------  -------------
                                                                                         -------------  -------------

 
                 See accompanying independent auditors' report
 
                                       10

                     PFIZER SAVINGS AND INVESTMENT PLAN FOR
                       EMPLOYEES RESIDENT IN PUERTO RICO
                            ITEM 27D -- SCHEDULE OF
                            REPORTABLE TRANSACTIONS
                               DECEMBER 31, 1995
 
FUNDS A, B, C AND COMPANY COMMON STOCK FUND:
 


                                                                              NUMBER OF      NUMBER OF
INVESTMENTS PURCHASED                                                       TRANSACTIONS      SHARES         COST
- -------------------------------------------------------------------------  ---------------  -----------  -------------
                                                                                                
Pfizer Inc. Common Stock.................................................            22         19,217*  $     875,645
Interest-bearing Deposits: Banco Popular de Puerto Rico, Time Deposits...           187             --       3,612,835

 


                                                     NUMBER OF      NUMBER OF                               REALIZED
INVESTMENTS DISPOSED                               TRANSACTIONS      SHARES         COST       FAIR VALUE     GAIN
- ------------------------------------------------  ---------------  -----------  -------------  -----------  ---------
                                                                                             
Pfizer Inc. Common Stock........................             4          4,150*  $     122,997      183,217     60,220
Interest-bearing Deposits: Banco Popular de
 Puerto Rico, Time Deposits.....................           143             --       3,562,139    3,562,139         --

 
* On  June 1995, Pfizer Inc. effected a two-for-one stock split in the form of a
  100% stock  dividend.  The  number  of shares  of  Pfizer  Inc.  common  stock
  purchased  and disposed of  by the Plan prior  to the date  of the stock split
  have been restated to reflect the split.
 
                 See accompanying independent auditors' report
 
                                       11

                          INDEPENDENT AUDITORS' REPORT
 
To the Administrative Committee
Pfizer Savings and Investment Plan for
Employees Resident in Puerto Rico:
 
    We have audited the accompanying statements of net assets available for plan
benefits  of the  Pfizer Savings and  Investment Plan for  Employees Resident in
Puerto Rico  (the Plan)  as  of December  31, 1995  and  1994, and  the  related
statements  of changes in net  assets available for plan  benefits for the years
then ended.  These financial  statements are  the responsibility  of the  Plan's
management.  Our  responsibility is  to express  an  opinion on  these financial
statements based on our audits.
 
    We conducted  our  audits in  accordance  with generally  accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement. An audit includes examining, on a test basis, evidence  supporting
the  amounts and disclosures in the financial statements. An audit also includes
assessing the  accounting  principles used  and  significant estimates  made  by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
 
    In our opinion, the financial  statements referred to above present  fairly,
in all material respects, the net assets available for plan benefits of the Plan
as  of December 31, 1995  and 1994, and the changes  in net assets available for
plan benefits for the  years then ended, in  conformity with generally  accepted
accounting principles.
 
    Our audits were performed for the purpose of forming an opinion on the basic
financial  statements taken as a whole. The supplemental schedules of (1) assets
held for investment purposes and (2) reportable transactions, as of and for  the
year  ended  December 31,  1995,  are presented  for  the purpose  of additional
analysis and are not a required part  of the basic financial statements but  are
supplementary  information  required  by  the Department  of  Labor's  Rules and
Regulations for Reporting  and Disclosure under  the Employee Retirement  Income
Security  Act of  1974. The  Fund Information  in the  statements of  net assets
available for  plan  benefits  and  the statements  of  changes  in  net  assets
available  for plan  benefits is presented  for purposes  of additional analysis
rather than to present the net assets available for plan benefits and changes in
net assets available for plan benefits of each Fund. The supplemental  schedules
and  Fund Information have been subjected  to the auditing procedures applied in
the audits of  the basic financial  statements and, in  our opinion, are  fairly
stated  in all material  respects in relation to  the basic financial statements
taken as a whole.
 
                                                 /s/ KPMG Peat Marwick LLP
                                          --------------------------------------
                                                   KPMG Peat Marwick LLP
February 6, 1996
 
Stamp No. 1308451 of the Puerto Rico
Society of Certified Public Accountants was
affixed to the record copy of this report.
 
                                       12

                                   SIGNATURES
 
    THE  PLAN.  Pursuant to  the requirements of the  Securities Exchange Act of
1934, the members of the Savings and Investment Plan Committee have duly  caused
this  annual report to be signed on its behalf by the undersigned thereunto duly
authorized.
 
                                          PFIZER SAVINGS AND INVESTMENT PLAN FOR
                                          EMPLOYEES RESIDENT IN PUERTO RICO
 
                                          By:        /S/ ANTHONY MADDALUNE
 
                                             -----------------------------------
                                                      Anthony Maddalune
                                                      GENERAL MANAGER,
                                                PFIZER PHARMACEUTICALS, INC.
                                                     CHAIR, SAVINGS AND
                                                  INVESTMENT PLAN COMMITTEE
 
Date: March 28,1996
 
                                       13

                                                                      EXHIBIT 23
 
                        CONSENT OF INDEPENDENT AUDITORS
 
To the Administrative Committee
Pfizer Savings and Investment Plan for
Employees Resident in Puerto Rico:
 
    We  consent to  the use  of our report  included herein  and incorporated by
reference in the  Registration Statement  on Form  S-8 dated  November 18,  1991
(File  No.  33-44053) of  our report  dated  February 6,  1996, relating  to the
statements of net assets available for  plan benefits of the Pfizer Savings  and
Investment  Plan for Employees Resident  in Puerto Rico as  of December 31, 1995
and 1994, and the related statements of changes in net assets available for plan
benefits for the years then ended, which report appears in the December 31, 1995
annual report  on  Form 11-K  of  the Pfizer  Savings  and Investment  Plan  for
Employees Resident in Puerto Rico.
 
                                                 /s/ KPMG Peat Marwick LLP
                                          --------------------------------------
                                                   KPMG Peat Marwick LLP
San Juan, Puerto Rico
March 28, 1996
 
                                       14