WARRANT NO. CSW-2

THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE BEEN ACQUIRED FOR 
INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR 
ANY STATE SECURITIES LAWS.  SUCH SECURITIES MAY NOT BE SOLD OR TRANSFERRED IN 
THE ABSENCE OF SUCH REGISTRATION OR AN EXEMPTION THEREFROM UNDER SAID ACT AND 
ANY APPLICABLE STATE SECURITIES LAWS.


                       WARRANT TO PURCHASE 10,000 SHARES
                              OF COMMON STOCK OF 
                           INHALE THERAPEUTIC SYSTEMS
                          (VOID AFTER OCTOBER 1, 2006)


    This certifies that Kiet Nguyen or his assigns (the "Holder"), for value
received, is entitled to purchase from Inhale Therapeutic Systems, a California
corporation (the "Company"), having a place of business at 1060 East Meadow
Circle, Palo Alto, California, 94303, a maximum of Ten Thousand (10,000) fully
paid and nonassessable shares of the Company's Common Stock for cash at a price
of $13.125 per share (the "Stock Purchase Price") at any time or from time to
time after the satisfaction of the conditions set forth in Section 1.1 below 
and until 5:00 p.m. (Pacific time) on October 1, 2006 (the "Expiration Date"), 
upon surrender to the Company at its principal office (or at such other 
location as the Company may advise the Holder in writing) of this Warrant 
properly endorsed with the Form of Subscription attached hereto duly filled in 
and signed and, if applicable, upon payment in cash or by check of the 
aggregate Stock Purchase Price for the number of shares for which this Warrant 
is being exercised determined in accordance with the provisions hereof.  The 
Stock Purchase Price and the number of shares purchasable hereunder are subject 
to adjustment as provided in Section 3 of this Warrant.

    This Warrant is subject to the following terms and conditions:

1.  Exercise; Issuance of Certificates; Payment for Shares.

    1.1  EXERCISABILITY.  This Warrant shall not be exercisable until such time
as T.M.T. Associates LLC ("Landlord") has completed one of the following two
conditions:  (a)  Landlord shall have closed the Tenant Improvement Loan
referred to in Section 3.1 of that certain Lease Agreement, dated October 2,
1996, by and between the Company and Landlord (the "Lease") and shall have
disbursed proceeds from such Tenant Improvement Loan of at least $5,000,000 to
the Company; or (b) in the event the Company waives Landlord's obligation to
procure the Tenant Improvement Loan under the Lease, Landlord shall have
procured a written loan commitment on the terms and conditions described in
Section 3.1(c) of the Lease from a lender meeting the qualifications set forth
in Section 3.1(c) of the Lease.  Upon the completion of one of the two
conditions set forth in the preceding sentence prior to the Expiration Date,
this Warrant shall be exercisable upon the terms and conditions set forth
herein.  If neither of the two


                                     1



conditions is satisfied prior to the Expiration Date, this Warrant shall not
become exercisable and shall expire and be of no further force or effect.

    1.2. GENERAL.  Subject to the requirements of Section 1.1 above, this
Warrant is exercisable at the option of the holder of record hereof up to the
Expiration Date for all or any part of the shares of Common Stock (but not for a
fraction of a share) which may be purchased hereunder.  The Company agrees that
the shares of Common Stock purchased under this Warrant shall be and are deemed
to be issued to the Holder hereof as the record owner of such shares as of the
close of business on the date on which this Warrant shall have been surrendered,
properly endorsed, the completed, executed Form of Subscription delivered and
payment made for such shares.  Certificates for the shares of Common Stock so
purchased, together with any other securities or property to which the Holder
hereof is entitled upon such exercise, shall be delivered to the Holder hereof
by the Company at the Company's expense within a reasonable time after the
rights represented by this Warrant have been so exercised.  In case of a
purchase of less than all the shares which may be purchased under this Warrant,
the Company shall cancel this Warrant and execute and deliver a new Warrant or
Warrants of like tenor for the balance of the shares purchasable under the
Warrant surrendered upon such purchase to the Holder hereof within a reasonable
time.  Each stock certificate so delivered shall be in such denominations of
Common Stock as may be requested by the Holder hereof and shall be registered in
the name of such Holder. 

    1.3. NET ISSUE EXERCISE.  Notwithstanding any provisions herein to the 
contrary, if the fair market value of one share of the Company's Common Stock 
is greater than the Stock Purchase Price (at the date of calculation as set 
forth below), in lieu of exercising this Warrant for cash, the Holder may 
elect to receive shares equal to the value (as determined below) of this 
Warrant (or the portion thereof being canceled) by surrender of this Warrant 
at the principal office of the Company together with the properly endorsed 
Form of Subscription and notice of such election in which event the Company 
shall issue to the Holder a number of shares of Common Stock computed using 
the following formula:

              X = Y (A-B)
                  -------
                    A

         Where      X =  the number of shares of Common Stock to be issued to 
                         the Holder
 
                    Y =  the number of shares of Common Stock purchasable 
                         under the Warrant or, if only a portion of the 
                         Warrant is being exercised, the portion of the Warrant 
                         being canceled (at the date of such calculation)

                    A =  the fair market value of one share of the Company's 
                         Common Stock (at the date of such calculation)

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                    B =  Stock Purchase Price (as adjusted to the date of such 
                         calculation)

For purposes of the above calculation, if the Common Stock is traded in a 
public market, the fair market value of one share of Common Stock shall be the 
average of the closing price of the Company's Common Stock reported for each 
of the five (5) business days immediately preceding the business day on which 
Holder delivers the Form of Subscription to the Company.  If the Common Stock 
is not traded in a public market, fair market value of one share of Common 
Stock shall be determined by the Company's Board of Directors in good faith.  
The Company and the Holder agree to report any exercise under this Section 1.3 
for federal and state income tax purposes in the following manner:  Holder 
will be treated as having excised a portion of the Warrant for X shares of the 
Company's Common Stock, and having paid the Stock Purchase Price due upon such 
exercise by surrendering to the Company another portion of the Warrant 
exercisable for a number of shares equal to Y-X, with such surrender portion 
of the Warrant valued at (Y-X)(A-B).

2.  SHARES TO BE FULLY PAID; RESERVATION OF SHARES.  The Company covenants and 
agrees that all shares of Common Stock which may be issued upon the exercise of
the rights represented by this Warrant will, upon issuance, be duly authorized,
validly issued, fully paid and nonassessable and free from all preemptive 
rights of any shareholder and free of all taxes, liens and charges with 
respect to the issue thereof. The Company further covenants and agrees that, 
during the period within which the rights represented by this Warrant may be 
exercised, the Company will at all times have authorized and reserved, for the 
purpose of issue or transfer upon exercise of the subscription rights evidenced 
by this Warrant, a sufficient number of shares of authorized but unissued Common
Stock, or other securities and property, when and as required to provide for 
the exercise of the rights represented by this Warrant.  The Company will take 
all such action as may be necessary to assure that such shares of Common Stock 
may be issued as provided herein without violation of any applicable law or 
regulation, or of any requirements of any domestic securities exchange upon 
which the Common Stock may be listed; provided, however, that the Company 
shall not be required to effect a registration under Federal or State 
securities laws with respect to such exercise.  The Company will not take any 
action which would result in any adjustment of the Stock Purchase Price (as 
set forth in Section 3 hereof) if the total number of shares of Common Stock 
issuable after such action upon exercise of all outstanding warrants, together 
with all shares of Common Stock then outstanding and all shares of Common 
Stock then issuable upon exercise of all options and upon the conversion of 
all convertible securities then outstanding, would exceed the total number of 
shares of Common Stock then authorized by the Company's Restated Articles of 
Incorporation.

3.  ADJUSTMENT OF STOCK PURCHASE PRICE AND NUMBER OF SHARES.  The Stock 
Purchase Price and the number of shares purchasable upon the exercise of this 
Warrant shall be subject to adjustment from time to time upon the occurrence 
of certain events described in this Section 3.  Upon each adjustment of the 
Stock Purchase Price, the Holder of this Warrant shall thereafter be entitled 
to purchase, at the Stock Purchase Price resulting from such adjustment, the 
number of shares obtained by multiplying the Stock Purchase Price in effect 
immediately prior to such adjustment by the number of shares purchasable 
pursuant hereto immediately prior to such 
                                     3


adjustment, and dividing the product thereof by the Stock Purchase Price 
resulting from such adjustment.

    3.1. SUBDIVISION OR COMBINATION OF STOCK.  In case the Company shall at 
any time subdivide its outstanding shares of Common Stock into a greater 
number of shares, the Stock Purchase Price in effect immediately prior to 
such subdivision shall be proportionately reduced, and conversely, in case 
the outstanding shares of Common Stock of the Company shall be combined into 
a smaller number of shares, the Stock Purchase Price in effect immediately 
prior to such combination shall be proportionately increased.

    3.2. DIVIDENDS IN COMMON STOCK, OTHER STOCK, PROPERTY, RECLASSIFICATION.  
If at any time or from time to time the Holders of Common Stock (or any 
shares of stock or other securities at the time receivable upon the exercise 
of this Warrant) shall have received or become entitled to receive, without 
payment therefor,

         (a)  Common Stock or any shares of stock or other securities which 
are at any time directly or indirectly convertible into or exchangeable for 
Common Stock, or any rights or options to subscribe for, purchase or 
otherwise acquire any of the foregoing by way of dividend or other 
distribution,

         (b)  any cash paid or payable otherwise than as a cash dividend, or

         (c)  Common Stock or additional stock or other securities or 
property (including cash) by way of spinoff, split-up, reclassification, 
combination of shares or similar corporate rearrangement, (other than shares 
of Common Stock issued as a stock split or adjustments in respect of which 
shall be covered by the terms of Section 3.1 above), then and in each such 
case, the Holder hereof shall, upon the exercise of this Warrant, be entitled 
to receive, in addition to the number of shares of Common Stock receivable 
thereupon, and without payment of any additional consideration therefor, the 
amount of stock and other securities and property (including cash in the 
cases referred to in clause (b) above and this clause (c)) which such Holder 
would hold on the date of such exercise had he been the holder of record of 
such Common Stock as of the date on which holders of Common Stock received or 
became entitled to receive such shares or all other additional stock and 
other securities and property.

    3.3. REORGANIZATION, RECLASSIFICATION, CONSOLIDATION, MERGER OR SALE.  If 
any recapitalization, reclassification or reorganization of the capital stock 
of the Company, or any consolidation or merger of the Company with another 
corporation, or the sale of all or substantially all of its assets or other 
transaction shall be effected in such a way that holders of Common Stock 
shall be entitled to receive stock, securities, or other assets or property 
(an "Organic Change"), then, as a condition of such Organic Change, lawful 
and adequate provisions shall be made by the Company whereby the Holder 
hereof shall thereafter have the right to purchase and receive (in lieu of 
the shares of the Common Stock of the Company immediately theretofore 
purchasable and receivable upon the exercise of the rights represented 
hereby) such shares of stock, securities or other assets or property as may 
be issued or payable with respect to or in exchange for a number of 
outstanding shares of such Common Stock equal to the number of 
                                     4


shares of such stock immediately theretofore purchasable and receivable upon 
the exercise of the rights represented hereby; provided, however, that in the 
event the value of the stock or securities (determined in good faith by the 
Board of Directors of the Company) issuable or payable with respect to one 
share of the Common Stock of the Company immediately theretofore purchasable 
and receivable upon the exercise of the rights represented hereby is in 
excess of the Stock Purchase Price hereof effective at the time of a merger 
and the stock or securities received in such reorganization, if any, are 
publicly traded and are freely tradeable by the Holder under Rule 144 or 145 
under the Securities Act of 1933, as amended, then this Warrant shall expire 
unless exercised prior to such Organic Change.  In the event of any Organic 
Change, appropriate provision shall be made by the Company with respect to 
the rights and interests of the Holder of this Warrant to the end that the 
provisions hereof (including, without limitation, provisions for adjustments 
of the Stock Purchase Price and of the number of shares purchasable and 
receivable upon the exercise of this Warrant) shall thereafter be applicable, 
in relation to any shares of stock, securities or assets thereafter 
deliverable upon the exercise hereof.

    3.4.      CERTAIN EVENTS.  If any change in the outstanding Common Stock 
of the Company or any other event occurs as to which the other provisions of 
this Section 3 are not strictly applicable or if strictly applicable would 
not fairly protect the purchase rights of the Holder of the Warrant in 
accordance with such provisions, then the Board of Directors of the Company 
shall make an adjustment in the number and class of shares available under 
the Warrant, the Stock Purchase Price or the application of such provisions, 
so as to protect such purchase rights as aforesaid.  The adjustment shall be 
such as will give the Holder of the Warrant upon exercise for the same 
aggregate Stock Purchase Price the total number, class and kind of shares as 
he would have owned had the Warrant been exercised prior to the event and had 
he continued to hold such shares until after the event requiring adjustment.

    3.5. NOTICES OF CHANGE.

         (a)  Promptly following any adjustment in the number or class of 
shares subject to this Warrant and of the Stock Purchase Price, the Company 
shall give written notice thereof to the Holder, setting forth in reasonable 
detail and certifying the calculation of such adjustment.

         (b)  The Company shall give written notice to the Holder at least 10 
business days prior to the date on which the Company closes its books or 
takes a record for determining rights to receive any dividends or 
distributions.

         (c)  The Company shall also give written notice to the Holder at 
least 15 business days prior to the date on which an Organic Change shall 
take place.

4.  ISSUE TAX.  The issuance of certificates for shares of Common Stock upon 
the exercise of the Warrant shall be made without charge to the Holder of the 
Warrant for any issue tax (other than any applicable income taxes) in respect 
thereof; provided, however, that the Company shall not be required to pay any 
tax which may be payable in respect of any transfer involved in the 

                                     5


issuance and delivery of any certificate in a name other than that of the 
then Holder of the Warrant being exercised.

5.  CLOSING OF BOOKS.  The Company will at no time close its transfer books 
against the transfer of any warrant or of any shares of Common Stock issued 
or issuable upon the exercise of any warrant in any manner which interferes 
with the timely exercise of this Warrant.

6.  NO VOTING OR DIVIDEND RIGHTS; LIMITATION OF LIABILITY.  Nothing contained 
in this Warrant shall be construed as conferring upon the Holder hereof the 
right to vote or to consent or to receive notice as a shareholder of the 
Company or any other matters or any rights whatsoever as a shareholder of the 
Company.  No dividends or interest shall be payable or accrued in respect of 
this Warrant or the interest represented hereby or the shares purchasable 
hereunder until, and only to the extent that, this Warrant shall have been 
exercised.  No provisions hereof, in the absence of affirmative action by the 
holder to purchase shares of Common Stock, and no mere enumeration herein of 
the rights or privileges of the holder hereof, shall give rise to any 
liability of such Holder for the Stock Purchase Price or as a shareholder of 
the Company, whether such liability is asserted by the Company or by its 
creditors.

7.  WARRANTS TRANSFERABLE.  Subject to compliance with applicable federal and 
state securities laws, this Warrant and all rights hereunder are 
transferable, in whole or in part, without charge to the holder hereof 
(except for transfer taxes), upon surrender of this Warrant properly 
endorsed.  Each taker and holder of this Warrant, by taking or holding the 
same, consents and agrees that this Warrant, when endorsed in blank, shall be 
deemed negotiable, and that the holder hereof, when this Warrant shall have 
been so endorsed, may be treated by the Company, at the Company's option, and 
all other persons dealing with this Warrant as the absolute owner hereof for 
any purpose and as the person entitled to exercise the rights represented by 
this Warrant, or to the transfer hereof on the books of the Company any 
notice to the contrary notwithstanding; but until such transfer on such 
books, the Company may treat the registered owner hereof as the owner for all 
purposes.

8.  RIGHTS AND OBLIGATIONS SURVIVE EXERCISE OF WARRANT.  The rights and 
obligations of the Company, of the holder of this Warrant and of the holder 
of shares of Common Stock issued upon exercise of this Warrant, referred to 
in Section 7 shall survive the exercise of this Warrant.

9.  MODIFICATION AND WAIVER.  This Warrant and any provision hereof may be 
changed, waived, discharged or terminated only by an instrument in writing 
signed by the party against which enforcement of the same is sought.

10. NOTICES.  Any notice, request or other document required or permitted to 
be given or delivered to the holder hereof or the Company shall be delivered 
or shall be sent by certified mail, postage prepaid, to each such holder at 
its address as shown on the books of the Company or to the Company at the 
address indicated therefor in the first paragraph of this Warrant or such 
other address as either may from time to time provide to the other.

                                     6


11. BINDING EFFECT ON SUCCESSORS.  This Warrant shall be binding upon any 
corporation succeeding the Company by merger, consolidation or acquisition of 
all or substantially all of the Company's assets.  All of the obligations of 
the Company relating to the Common Stock issuable upon the exercise of this 
Warrant shall survive the exercise and termination of this Warrant.  All of 
the covenants and agreements of the Company shall inure to the benefit of the 
successors and assigns of the holder hereof.  

12. DESCRIPTIVE HEADINGS AND GOVERNING LAW.  The description headings of the 
several sections and paragraphs of this Warrant are inserted for convenience 
only and do not constitute a part of this Warrant.  This Warrant shall be 
construed and enforced in accordance with, and the rights of the parties 
shall be governed by, the laws of the State of California.

13. LOST WARRANTS.  The Company represents and warrants to the Holder hereof 
that upon receipt of evidence reasonably satisfactory to the Company of the 
loss, theft, destruction, or mutilation of this Warrant and, in the case of 
any such loss, theft or destruction, upon receipt of an indemnity reasonably 
satisfactory to the Company, or in the case of any such mutilation upon 
surrender and cancellation of such Warrant, the Company, at its expense, will 
make and deliver a new Warrant, of like tenor, in lieu of the lost, stolen, 
destroyed or mutilated Warrant.  

14. FRACTIONAL SHARES.  No fractional shares shall be issued upon exercise of 
this Warrant.  The Company shall, in lieu of issuing any fractional share, 
pay the holder entitled to such fraction a sum in cash equal to such fraction 
multiplied by the then effective Stock Purchase Price.

                        [THIS SPACE INTENTIONALLY LEFT BLANK]
                                     7


    IN WITNESS WHEREOF, the Company has caused this Warrant to be duly 
executed by its officers, thereunto duly authorized this 1st day of November, 
1996.

                                  INHALE THERAPEUTIC SYSTEMS,
                                  a California corporation


                                      /s/ Robert B. Chess
                                  ----------------------------
                                       Robert B. Chess
                                       President

ATTEST:


/s/ Mark P. Tanoury
- ---------------------------
Mark P. Tanoury
Secretary


                                     8



                                      EXHIBIT A
                                           
                                  SUBSCRIPTION FORM
                                           
                                               Date:                 , 19
                                                    ------------------    ----

Inhale Therapeutic Systems
1060 East Meadow Circle
Palo Alto, CA 94303

Attn:  President

Ladies and Gentlemen:

/ /  The undersigned hereby elects to exercise the warrant issued to it by 
     Inhale Therapeutic Systems (the "Company") and dated November 1, 1996
     Warrant No. CSW-2 (the "Warrant") and to purchase thereunder 
     __________________________________ shares of the Common Stock of the 
     Company (the "Shares") at a purchase price of _______________________ 
     Dollars ($__________) per Share or an aggregate purchase price of 
     ____________________ Dollars ($__________) (the      "Purchase Price").

/ /  The undersigned hereby elects to convert _______________________ percent 
     (____%) of the value of the Warrant pursuant to the provisions of Section 
     1.3 of the Warrant.

     Pursuant to the terms of the Warrant the undersigned has delivered the 
Purchase Price herewith in full in cash or by certified check or wire 
transfer.  The undersigned also makes the representations set forth on the 
attached Exhibit B of the Warrant.

                              Very truly yours,

                              --------------------------------


                              By:
                                 -----------------------------

                              Title:
                                    --------------------------




                                      EXHIBIT B
                                           
                              INVESTMENT REPRESENTATION
                                           
                                                Date:                 , 19
                                                    ------------------    ----


Inhale Therapeutic Systems
1060 East Meadow Circle
Palo Alto, CA 94303

Attn:  President

Ladies and Gentlemen:

     The undersigned, _________________________ ("Purchaser"), intends to 
acquire up to ______________ shares of the Common Stock (the "Common Stock") 
of Inhale Therapeutic Systems (the "Company") from the Company pursuant to 
the exercise of that certain Warrant to purchase Common Stock held by 
Purchaser.  The Common Stock will be issued to Purchaser in a transaction not 
involving a public offering and pursuant to an exemption from registration 
under the Securities Act of 1933, as amended (the "1933 Act") and applicable 
state securities laws.  In connection with such purchase and in order to 
comply with the exemptions from registration relied upon by the Company, 
Purchaser represents, warrants and agrees as follows:

     Purchaser is acquiring the Common Stock for its own account, to hold for 
investment, and Purchaser shall not make any sale, transfer or other 
disposition of the Common Stock in violation of the 1933 Act or the General 
Rules and Regulations promulgated thereunder by the Securities and Exchange 
Commission (the "SEC") or in violation of any applicable state securities law.

     Purchaser has been advised that the Common Stock has not been registered 
under the 1933 Act or state securities laws on the ground that this 
transaction is exempt from registration, and that reliance by the Company on 
such exemptions is predicated in part on Purchaser's representations set 
forth in this letter.

     Purchaser has been informed that under the 1933 Act, the Common Stock 
must be held indefinitely unless it is subsequently registered under the 1933 
Act or unless an exemption from such registration (such as Rule 144) is 
available with respect to any proposed transfer or disposition by Purchaser 
of the Common Stock.  Purchaser further agrees that the Company may refuse to 
permit Purchaser to sell, transfer or dispose of the Common Stock (except as 
permitted under Rule 144) unless there is in effect a registration statement 
under the 1933 Act and any applicable state securities laws covering such 
transfer, or unless Purchaser furnishes an opinion of counsel reasonably 
satisfactory to counsel for the Company, to the effect that such registration 
is not required.



     Purchaser also understands and agrees that there will be placed on the 
certificate(s) for the Common Stock, or any substitutions therefor, a legend 
stating in substance:
     
          "The shares represented by this certificate have not been 
     registered under the Securities Act of 1933, as amended (the      
     "Securities Act"), or any state securities laws.  These shares
     have been acquired for investment and may not be sold or otherwise      
     transferred in the absence of an effective registration statement
     for these shares under the Securities Act and applicable state
     securities laws, or an opinion of counsel satisfactory to the
     Company that registration is not required and that an applicable
     exemption is available."
     
     Purchaser has carefully read this letter and has discussed its 
requirements and other applicable limitations upon Purchaser's resale of 
the Common Stock with Purchaser's counsel.

                              Very truly yours,

                              --------------------------------


                              By:
                                 -----------------------------

                              Title:
                                    --------------------------

                                     3