PURCHASE AGREEMENT


           THIS AGREEMENT is made as of the 28th day of January, 1997, by and 
among Inhale Therapeutic Systems (the "Company"), a corporation organized 
under the laws of the State of California, with its principal offices at 1060 
East Meadow Circle, Palo Alto, California, 94303, and the purchaser whose 
name and address is set forth on the signature page hereof (the "Purchaser"). 

           IN CONSIDERATION of the mutual covenants contained in this 
Agreement, the Company, and the Purchaser agree as follows: 

           SECTION 1.  AUTHORIZATION OF SALE OF THE SHARES. Subject to the 
terms and conditions of this Agreement, the Company has authorized the sale 
of up to 1,800,000 shares of the common stock (the "Common Stock"), no par 
value per share (the "Shares"), of the Company. 

           SECTION 2.  AGREEMENT TO SELL AND PURCHASE THE SHARES.  At the 
Closing (as defined in Section 3), the Company will sell to the Purchaser, 
and the Purchaser will buy from the Company upon the terms and conditions 
hereinafter set forth, the number of Shares (at the purchase price) shown 
below: 

                                Price Per
       Number to Be              Share In                    Aggregate
        Purchased                 Dollars                      Price
       ------------             ----------                   ---------



           The Company proposes to enter into this same form of purchase 
agreement with certain other investors (the "Other Purchasers") and expects 
to complete sales of the Shares to them. The Purchaser and the Other 
Purchasers are hereinafter sometimes collectively referred to as the 
"Purchasers," and this Agreement and the agreements executed by the Other 
Purchasers are hereinafter sometimes collectively referred to as the 
"Agreements."  The term "Placement Agent" shall mean Vector Securities 
International, Inc.

           SECTION 3.  DELIVERY OF THE SHARES AT THE CLOSING.  The completion 
of the purchase and sale of the Shares (the "Closing") shall occur as soon as 
practicable following notification by the Securities and Exchange Commission 
(the "Commission") to the Company of the Commission's willingness to declare 
effective the



registration statement to be filed by the Company pursuant to 
Section 7.1 (the "Registration Statement") at a place and time (the "Closing 
Date") to be agreed upon by the Company, and the Placement Agent and of which 
the Purchasers will be notified by facsimile transmission or otherwise.

           At the Closing, the Company shall deliver to the Purchaser one or 
more stock certificates registered in the name of the Purchaser, or in such 
nominee name(s) as designated by the Purchaser, representing the number of 
Shares set forth in Section 2 above.  The name(s) in which the stock 
certificates are to be registered are set forth in the Stock Certificate 
Questionnaire attached hereto as part of Appendix I.  The Company's 
obligation to complete the purchase and sale of the Shares and deliver such 
stock certificate(s) to the Purchaser at the Closing shall be subject to the 
following conditions, any one or more of which may be waived by the Company:  
(a) receipt by the Company of New York Clearing House funds in the full 
amount of the purchase price for the Shares being purchased hereunder; (b) 
completion of the purchases and sales under the Agreements with Other 
Purchasers; and (c) the accuracy of the representations and warranties made 
by the Purchasers and the fulfillment of those undertakings of the Purchasers 
to be fulfilled prior to the Closing.  The Purchaser's obligation to accept 
delivery of such stock certificate(s) and to pay for the Shares evidenced 
thereby shall be subject to the following conditions:  (a) the Registration 
Statement is effective and was first declared effective on or prior to the 
60th day after the date such Registration Statement was filed by the Company; 
and (b) the accuracy in all material respects of the representations and 
warranties made by the Company herein and the fulfillment in all material 
respects of those undertakings of the Company to be fulfilled prior to 
Closing. The Purchaser's obligations hereunder are expressly not conditioned 
on the purchase by any or all of the Other Purchasers of the Shares that they 
have agreed to purchase from the Company.

    SECTION 4.  REPRESENTATIONS, WARRANTIES AND COVENANTS OF THE COMPANY. The
Company hereby represents and warrants to, and covenants with, the Purchaser as
follows: 

           4.1. ORGANIZATION AND QUALIFICATION.  The Company is a corporation 
duly organized, validly existing and in good standing under the laws of the 
State of California and has all requisite corporate power and authority to 
conduct its business as currently conducted.  

           4.2. AUTHORIZED CAPITAL STOCK.  Except as disclosed in or 
contemplated by the Confidential Private Placement Memorandum dated January 
27, 1997 prepared by the Company (the "Private Placement Memorandum"), the 
Company had authorized and outstanding capital stock as set forth under the 
heading "Capitalization" in the Private Placement Memorandum as of the 

                                   -2-




date set forth therein; the issued and outstanding shares of the Company's 
Common Stock have been duly authorized and validly issued, are fully paid and 
nonassessable, have been issued in compliance with all federal and state 
securities laws, were not issued in violation of or subject to any preemptive 
rights or other rights to subscribe for or purchase securities, and conform 
to the description thereof contained in or incorporated by reference into the 
Private Placement Memorandum.  All issued and outstanding shares of capital 
stock of each subsidiary of the Company have been duly authorized and validly 
issued and are fully paid and nonassessable.  Except as disclosed in or 
contemplated by the Private Placement Memorandum and the financial statements 
of the Company, and the related notes thereto, incorporated by reference into 
the Private Placement Memorandum, neither the Company nor any subsidiary has 
outstanding any options to purchase, or any preemptive rights or other rights 
to subscribe for or to purchase, any securities or obligations convertible 
into, or any contracts or commitments to issue or sell, shares of its capital 
stock or any such options, rights, convertible securities or obligations.  
The description of the Company's stock, stock bonus and other stock plans or 
arrangements and the options or other rights granted and exercised 
thereunder, set forth in the Private Placement Memorandum, or incorporated by 
reference therein, accurately and fairly presents the information required to 
be shown with respect to such plans, arrangements, options and rights.

           4.3. ISSUANCE, SALE AND DELIVERY OF THE SHARES.  The  Shares have 
been duly authorized and, when issued, delivered and paid for in the manner 
set forth in this Agreement, will be duly authorized, validly issued, fully 
paid and nonassessable, and will conform to the description thereof contained 
in the Registration Statement.  No preemptive rights or other rights to 
subscribe for or purchase exist with respect to the issuance and sale of the 
Shares by the Company pursuant to this Agreement.  No stockholder of the 
Company has any right (which has not been waived or has not expired by reason 
of lapse of time following notification of the Company's intent to file the 
Registration Statement) to require the Company to register the sale of any 
shares owned by such stockholder under the Securities Act of 1933, as 
amended, (the "Securities Act") in the Registration Statement.  No further 
approval or authority of the stockholders or the Board of Directors of the 
Company will be required for the issuance and sale of the Shares to be sold 
by the Company as contemplated herein.

           4.4. DUE EXECUTION, DELIVERY AND PERFORMANCE OF THE AGREEMENTS.  
The Company has full legal right, power and authority to enter into the 
Agreements and perform the transactions contemplated hereby.  The Agreements 
have been duly authorized, executed and delivered by the Company and 
constitute valid and binding obligations of the Company in accordance with

                                    -3-



their terms.  The making and performance of the Agreements by the Company and 
the consummation of the transactions herein contemplated will not violate any 
provision of the certificate of incorporation or bylaws, or other 
organizational documents, of the Company or any of its subsidiaries, and will 
not conflict with, result in the breach or violation of, or constitute, 
either by itself or upon notice or the passage of time or both, a default 
under any agreement, mortgage, deed of trust, lease, franchise, license, 
indenture, permit or other instrument to which the Company or any of its 
subsidiaries is a party or by which the Company or any of its subsidiaries or 
any of its respective properties may be bound or affected, any statute or any 
authorization, judgment, decree, order, rule or regulation of any court or 
any regulatory body, administrative agency or other governmental body 
applicable to the Company or any of its subsidiaries or any of their 
respective properties.  No consent, approval, authorization or other order of 
any court, regulatory body, administrative agency or other governmental body 
is required for the execution and delivery of this Agreement or the 
consummation of the transactions contemplated by this Agreement, except for 
compliance with the Blue Sky laws applicable to the offering of the Shares.  
Upon their execution and delivery, and assuming the valid execution thereof 
by the respective Purchasers, the Agreements will constitute valid and 
binding obligations of the Company, enforceable in accordance with their 
respective terms, except as enforceability may be limited by applicable 
bankruptcy, insolvency, reorganization, moratorium or similar laws affecting 
creditors' and contracting parties' rights generally and except as 
enforceability may be subject to general principles of equity (regardless of 
whether such enforceability is considered in a proceeding in equity or at 
law) and except as the indemnification agreements of the Company in Section 
7.3 hereof may be legally unenforceable. 

           4.5. ACCOUNTANTS.  Ernst & Young LLP, who have expressed their 
opinion with respect to the financial statements and schedules to be filed 
with the Commission as a part of the Registration Statement and included in 
the Registration Statement and the Prospectus which forms a part thereof, are 
independent accountants as required by the Securities Act and the rules and 
regulations promulgated thereunder (the "Rules and Regulations").

           4.6. NO DEFAULTS.  Except as to defaults, violations and breaches 
which individually or in the aggregate would not be material to the Company, 
neither the Company nor any of its subsidiaries is in violation or default of 
any provision of its certificate of incorporation or bylaws, or other 
organizational documents, or is in breach of or default with respect to any 
provision of any agreement, judgment, decree, order, mortgage, deed of trust, 
lease, franchise, license, indenture, permit or other instrument to which it 
is a party or by which it or any of its properties are bound; and there does 
not exist any state of

                                   -4-



fact which constitutes an event of default on the part of the Company or 
any such subsidiary as defined in such documents or which, with notice or 
lapse of time or both, would constitute such an event of default, except such 
defaults which individually or in the aggregate would not be material to the 
Company.

           4.7. CONTRACTS.  The contracts so described in the Private 
Placement Memorandum or incorporated by reference therein are in full force 
and effect on the date hereof; and neither the Company nor any of its 
subsidiaries, nor to the best of the Company's knowledge, any other party is 
in breach of or default under any of such contracts.

           4.8. NO ACTIONS.  Except as disclosed in the Private Placement 
Memorandum or incorporated by reference therein, there are no legal or 
governmental actions, suits or proceedings pending or, to the best of the 
Company's knowledge, threatened to which the Company or any of its 
subsidiaries is or may be a part or of which property owned or leased by the 
Company or any of its subsidiaries is or may be the subject, or related to 
environmental or discrimination matters, which actions, suits or proceedings 
might, individually or in the aggregate, prevent or adversely affect the 
transactions contemplated by this Agreement or result in a material adverse 
change in the condition (financial or otherwise), properties, business, 
results of operations or prospects of the Company and its subsidiaries; and 
no labor disturbance by the employees of the Company or any of its 
subsidiaries exists or is imminent which might be expected to affect 
adversely such condition, properties, business, results of operations or 
prospects.  Neither the Company nor any of its subsidiaries is party or 
subject to the provisions of any material injunction, judgment, decree or 
order of any court, regulatory body administrative agency or other 
governmental body.

           4.9. PROPERTIES.  The Company has good and marketable title to all 
the properties and assets reflected as owned in the financial statements 
included in the Private Placement Memorandum or incorporated by reference 
therein, subject to no lien, mortgage, pledge, charge or encumbrance of any 
kind except (i) those, if any, reflected in such financial statements, or 
(ii) those which are not material in amount and do not adversely affect the 
use made and promised to be made of such property by the Company and its 
subsidiaries.  The Company or the applicable subsidiary holds its leased 
properties under valid and binding leases, with such exceptions as are not 
materially significant in relation to the business of the Company.  Except as 
disclosed in the Private Placement Memorandum or incorporated by reference 
therein, the Company owns or leases all such properties as are necessary to 
its operations as now conducted or as proposed to be conducted.

                                   -5-



           4.10. NO MATERIAL CHANGE.  Since September 30, 1996 and except as 
described in or specifically contemplated by the Private Placement 
Memorandum, (i) the Company and its subsidiaries have not incurred any  
material liabilities or obligations, indirect, or contingent, or entered into 
any material verbal or written agreement or other transaction which is not in 
the ordinary course of business or which could result in a material reduction 
in the future earnings of the Company and its subsidiaries; (ii) the Company 
and its subsidiaries have not sustained any material loss or interference 
with their respective businesses or properties from fire, flood, windstorm, 
accident or other calamity, whether or not covered by insurance; (iii) the 
Company has not paid or declared any dividends or other distributions with 
respect to its capital stock and the Company and its subsidiaries are not in 
default in the payment of principal or interest on any outstanding debt 
obligations; (iv) there has not been any change in the capital stock other 
than the sale of the Shares hereunder, shares issued pursuant to employee 
equity incentive plans or purchase plans approved by the Company's Board of 
Directors, and 272,456 shares issued to Pfizer Inc., or indebtedness material 
to the Company and its subsidiaries (other than in the ordinary course of 
business); and (v) there has not been any material adverse change in the 
condition (financial or otherwise), business, properties, results of 
operations or prospects of the Company and its subsidiaries.

           4.11. INTELLECTUAL PROPERTY.  Except as disclosed in or 
specifically contemplated by the Private Placement Memorandum or incorporated 
by reference therein, the Company has sufficient trademarks, trade names, 
patent rights, copyrights, licenses, and governmental authorizations to 
conduct its businesses as now conducted; and the Company has no knowledge of 
any material infringement by it of trademark, trade name rights, patent 
rights, copyrights, licenses, trade secrets or other similar rights of 
others, and no claim has been made against the Company regarding trademark, 
trade name, patent, copyright, license, trade secrecy or other infringement 
which could have a material adverse effect on the condition (financial or 
otherwise), business, results of operations or prospects of the Company.

           4.12. COMPLIANCE.  The Company has not been advised, and has no 
reason to believe, that either it or any of its subsidiaries is not 
conducting business in compliance with all applicable laws, rules and 
regulations of the jurisdictions in which it is conducting business, 
including, without limitation, all applicable local, state and federal 
environmental laws and regulations; except where failure to be so in 
compliance would not materially adversely affect the condition (financial or 
otherwise), business, results of operations or prospects of the Company and 
its subsidiaries.

                                 -6-



           4.13. TAXES.  The Company and its subsidiaries have filed all 
necessary federal, state and foreign income and franchise tax returns and 
have paid or accrued all taxes shown as due thereon, and the Company has no 
knowledge of tax deficiency which has been or might be asserted or threatened 
against the Company or its subsidiaries which could materially and adversely 
affect the business, operations or properties of the Company and its 
subsidiaries.

           4.14. TRANSFER TAXES.  On the Closing Date, all stock transfer or 
other taxes (other than income taxes) which are required to be paid in 
connection with the sale and transfer of the Shares to be sold to the 
Purchaser hereunder will be, or will have been, fully paid or provided for by 
the Company and all laws imposing such taxes will be or will have been fully 
complied with.

           4.15. INVESTMENT COMPANY.  The Company is not an "investment 
company" within the meaning of the Investment Company Act of 1940, as amended.

           4.16. OFFERING MATERIALS.  The Company has not distributed and 
will not distribute prior to the Closing Date any offering material in 
connection with the offering and sale of the Shares other than the Private 
Placement Memorandum.

           4.17. INSURANCE.  Each of the Company and its subsidiaries 
maintains insurance of the types and in the amounts generally deemed adequate 
for its business, including, but not limited to, insurance covering all real 
and personal property owned or leased by the Company and its subsidiaries 
against theft, damage, destruction, acts of vandalism and all other risks 
customarily insured against, all of which insurance is in full force and 
effect.

           4.18. CONTRIBUTIONS.  Neither the Company nor any of its 
subsidiaries has, directly or indirectly, at any time during the last five 
years (i) made any unlawful contribution to any candidate for public office, 
or failed to disclose fully any contribution in violation of law, or (ii) 
made any payment to any federal or state governmental officer or official, or 
other person charged with similar public or quasi-public duties, other than 
payments required or permitted by the laws of the United States or any 
jurisdiction thereof.

           4.19. ADDITIONAL INFORMATION.   The Company represents and 
warrants that the information contained in the following documents, which the 
Placement Agent have furnished to the Purchaser, or will furnish prior to the 
Closing, is or will be true and correct in all material respects as of their 
respective final dates: 

                               -7-



           (a)  the Company's 1996 Annual Report to Shareholders; 

           (b)  the Company's Annual Report on Form 10-K for the fiscal year 
                ended December 31, 1995 (without exhibits);  
    
           (c)  Notice to Shareholders and Proxy Statement for the Company's
                Annual Meeting of Shareholders held on May 15, 1996;

           (d)  the Confidential Placement Memorandum dated January 27, 1997
                containing certain summary information relating to the sale by
                the Company of the Shares pursuant to the Agreements, 
                including all addenda and exhibits thereto (other than the 
                Appendices) (the "Private Placement Memorandum");

           (e)  all other documents, if any, filed by the Company 
                with the Securities and Exchange Commission since December 31,
                1995 pursuant to the reporting requirements of the Securities 
                Exchange Act of 1934, as amended (the "Exchange Act").

           4.20. LEGAL OPINION.  Prior to the Closing, Cooley Godward LLP, 
counsel to the Company, will deliver its legal opinion to the Placement Agent 
reasonably satisfactory to the Placement Agent and counsel to the Placement 
Agent.  Such opinion shall also state that each of the Purchasers may rely 
thereon as though it were addressed directly to such Purchaser.

           4.21. CERTIFICATE.  A certificate of the Company executed by the 
Chairman of the Board or President and the chief financial or accounting 
officer of the Company, dated the Closing Date in form and substance 
satisfaction to the Purchasers to the effect that the representations and 
warranties of the Company set forth in this Section 4 are true and correct as 
of the date of this Agreement and as of the Closing Date, and the Company has 
complied with all the agreements and satisfied all the conditions on its part 
to be performed or satisfied on or prior to such Closing Date.

           SECTION 5.  REPRESENTATIONS, WARRANTIES AND COVENANTS OF THE 
PURCHASER. (a) The Purchaser represents and warrants to, and covenants with, 
the Company that: (i) the Purchaser, taking into account the personnel and 
resources it can practically bring to bear on the purchase of the Shares 
contemplated hereby, is knowledgeable, sophisticated and experienced in 
making, and is qualified to make, decisions with respect to investments in 
shares representing an investment decision like that involved in the purchase 
of the Shares, including investments in securities issued by the Company, and 
has requested, received, reviewed and considered all information it deems 
relevant in making an

                               -8-



informed decision to purchase the Shares; (ii) the Purchaser is acquiring the 
number of Shares set forth in Section 2 above in the ordinary course of its 
business and for its own account for investment (as defined for purposes of 
the Hart-Scott-Rodino Antitrust Improvement Act of 1976 and the regulations 
thereunder) only and with no present intention of distributing any of such 
Shares or any arrangement or understanding with any other persons regarding 
the distribution of such Shares; (iii) the Purchaser will not, directly or 
indirectly, offer, sell, pledge, transfer or otherwise dispose of (or solicit 
any offers to buy, purchase or otherwise acquire or take a pledge of) any of 
the Shares except in compliance with the Act, and the Rules and Regulations; 
(iv) the Purchaser has completed or caused to be completed the Registration 
Statement Questionnaire and the Stock Certificate Questionnaire, both 
attached hereto as Appendix I, for use in preparation of the Registration 
Statement and the answers thereto are true and correct to the best knowledge 
of the Purchaser as of the date hereof and will be true and correct as of the 
effective date of the Registration Statement; (v) the Purchaser has, in 
connection with its decision to purchase the number of Shares set forth in 
Section 2 above, relied solely upon the Private Placement Memorandum and the 
documents included therein and the representations and warranties of the 
Company contained herein; and (vi) the Purchaser is an "accredited investor" 
within the meaning of Rule 501 of Regulation D promulgated under the 
Securities Act.

           (b) The Purchaser hereby covenants with the Company not to make 
any sale of the Shares without effectively causing the prospectus delivery 
requirement under the Securities Act to be satisfied, and the Purchaser 
acknowledges and agrees that such Shares are not transferable on the books of 
the Company unless the certificate submitted to the transfer agent evidencing 
the Shares is accompanied by a separate officer's certificate:  (i) in the 
form of Appendix II hereto, (ii) executed by an officer of, or other 
authorized person designated by, the Purchaser, and (iii) to the effect that 
(A) the Shares have been sold in accordance with the Registration Statement, 
the Securities Act and the Rules and Regulations and any applicable state 
securities or blue sky laws and (B) the requirement of delivering a current 
prospectus has been satisfied.  The Purchaser acknowledges that there may 
occasionally be times when the Company must suspend the use of the prospectus 
forming a part of the Registration Statement until such time as an amendment 
to the Registration Statement has been filed by the Company and declared 
effective by the Commission, or until such time as the Company has filed an 
appropriate report with the Commission pursuant to the Exchange Act.  The 
Purchaser hereby covenants that it will not sell any Shares pursuant to said 
prospectus during the period commencing at the time at which the Company 
gives the Purchaser

                               -9-



notice of the suspension of the use of said prospectus and ending at the time 
the Company gives the Purchaser notice that the Purchaser may thereafter 
effect sales pursuant to said prospectus.  The Purchaser further covenants to 
notify the Company promptly of the sale of all of its Shares.

           (c) The Purchaser further represents and warrants to, and 
covenants with, the Company that (i) the Purchaser has full right, power, 
authority and capacity to enter into this Agreement and to consummate the 
transactions contemplated hereby and has taken all necessary action to 
authorize the execution, delivery and performance of this Agreement, and (ii) 
upon the execution and delivery of this Agreement, this Agreement shall 
constitute a valid and binding obligation of the Purchaser enforceable in 
accordance with its terms, except as enforceability may be limited by 
applicable bankruptcy, insolvency, reorganization, moratorium or similar laws 
affecting creditors' and contracting parties' rights generally and except as 
enforceability may be subject to general principles of equity (regardless of 
whether such enforceability is considered in a proceeding in equity or at 
law) and except as the indemnification agreements of the Purchaser in Section 
7.3 hereof may be legally unenforceable. 

           SECTION 6.  SURVIVAL OF REPRESENTATIONS, WARRANTIES AND 
AGREEMENTS. Notwithstanding any investigation made by any party to this 
Agreement or by the Placement Agent, all covenants, agreements, 
representations and warranties made by the Company and the Purchaser herein 
and in the certificates for the Shares delivered pursuant hereto shall 
survive the execution of this Agreement, the delivery to the Purchaser of the 
Shares being purchased and the payment therefor. 

           SECTION 7.  REGISTRATION OF THE SHARES; COMPLIANCE WITH THE 
SECURITIES ACT. 

           7.1. REGISTRATION PROCEDURES AND EXPENSES.  The Company shall: 

           (a)  as soon as practicable, prepare and file 
                with the Commission the Registration Statement on Form 
                S-3 relating to the sale of the Shares by the Purchaser 
                from time to time through the automated quotation system 
                of The Nasdaq Stock Market or the facilities of any 
                national securities exchange on which the Company's 
                common stock is then traded or in privately-negotiated 
                transactions; 

           (b)  use its reasonable efforts, subject to 
                receipt of necessary information from the Purchasers, to 
                cause the Commission to notify the Company of the 
                Commission's willingness to declare the Registration 
                Statement effective within 60 days after the Registration 
                Statement is filed by the Company; 

                                -10-



           (c)  prepare and file with the Commission such 
                amendments and supplements to the Registration Statement 
                and the prospectus used in connection therewith as may be 
                necessary to keep the Registration Statement effective 
                until the date on which the Shares may be resold by the 
                Purchasers without registration by reason of Rule 144(k)
                under the Securities Act or any other rule of similar 
                effect;
  
           (d)  furnish to the Purchaser with respect to 
                the Shares registered under the Registration Statement 
                (and to each underwriter, if any, of such Shares) such 
                reasonable number of copies of prospectuses and such 
                other documents as the Purchaser may reasonably request, 
                in order to facilitate the public sale or other 
                disposition of all or any of the Shares by the Purchaser, 
                PROVIDED, HOWEVER, that the obligation of the Company to 
                deliver copies of prospectuses to the Purchaser shall be 
                subject to the receipt by the Company of reasonable 
                assurances from the Purchaser that the Purchaser will 
                comply with the applicable provisions of the Securities 
                Act and of such other securities or blue sky laws as may 
                be applicable in connection with any use of such 
                prospectuses; 

           (e)  file documents required of the Company 
                for normal blue sky clearance in states specified in 
                writing by the Purchaser, PROVIDED, HOWEVER, that the 
                Company shall not be required to qualify to do business 
                or consent to service of process in any jurisdiction in 
                which it is not now so qualified or has not so consented; 
                and 

           (f)  bear all expenses in connection with the 
                procedures in paragraphs (a) through (e) of this Section 
                7.1 and the registration of the Shares pursuant to the 
                Registration Statement, other than  fees and expenses, if 
                any, of counsel or other advisers to the Purchaser or the 
                Other Purchasers or underwriting discounts, brokerage 
                fees and commissions incurred by the Purchaser or the 
                Other Purchasers, if any.
 
           7.2. TRANSFER OF SHARES AFTER REGISTRATION.  The Purchaser agrees 
that it will not effect any disposition of the Shares or its right to 
purchase the Shares that would constitute a sale within the meaning of the 
Securities Act except as contemplated in the Registration Statement referred 
to in Section 7.1 and that it will promptly notify the Company of any changes 

                                 -11-



in the information set forth in the Registration Statement regarding the 
Purchaser or its Plan of Distribution. 

           7.3. INDEMNIFICATION.  For the purpose of this Section 7.3: 

           (i)  the term "Purchaser/Affiliate" shall include the Purchaser 
                and any affiliate of such Purchaser; 

           (ii) the term "Registration Statement" shall include any final 
                prospectus, exhibit, supplement or amendment included in or
                relating to the Registration Statement referred to in 
                Section 7.1. 

           (a)  The Company agrees to indemnify and hold harmless each of the 
Purchasers and each person, if any, who controls any Purchaser within the 
meaning of the Securities Act, against any losses, claims, damages, 
liabilities or expenses, joint or several, to which such Purchasers or such 
controlling person may become subject, under the Securities Act, the Exchange 
Act, or any other federal or state statutory law or regulation, or at common 
law or otherwise (including in settlement of any litigation, if such 
settlement is effected with the written consent of the Company), insofar as 
such losses, claims, damages, liabilities or expenses (or actions in respect 
thereof as contemplated below) arise out of or are based upon any untrue 
statement or alleged untrue statement of any material fact contained in the 
Registration Statement, including the prospectus, financial statements and 
schedules, and all other documents filed as a part thereof, as amended at the 
time of effectiveness of the Registration Statement, including any 
information deemed to be a part thereof as of the time of effectiveness 
pursuant to paragraph (b) of Rule 430A, or pursuant to Rule 434, of the Rules 
and Regulations, or the prospectus, in the form first filed with the 
Commission pursuant to Rule 424(b) of the Regulations, or filed as part of 
the Registration Statement at the time of effectiveness if no Rule 424(b) 
filing is required (the "Prospectus"), or any amendment or supplement 
thereto, or arise out of or are based upon the omission or alleged omission 
to state in any of them a material fact required to be stated therein or 
necessary to make the statements in any of them not misleading, or arise out 
of or are based in whole or in part on any inaccuracy in the representations 
and warranties of the Company contained in this Agreement, or any failure of 
the Company to perform its obligations hereunder or under law, and will 
reimburse each Purchaser and each such controlling person for any legal and 
other expenses as such expenses are reasonably incurred by such Purchaser or 
such controlling person in connection with investigating, defending, 
settling, compromising or paying any such loss, claim, damage, liability, 
expense or action; PROVIDED, HOWEVER, that the Company will not be liable in 
any such case to the extent that any such loss, claim, damage, 

                               -12-




liability or expense arises out of or is based upon an untrue statement or 
alleged untrue statement or omission or alleged omission made in the 
Registration Statement, the Prospectus or any amendment or supplement thereto 
in reliance upon and in conformity with written information furnished to the 
Company (i) by or on behalf of the Purchaser expressly for use therein or 
(ii) the failure of such Purchaser to comply with the covenants and 
agreements contained in Sections 5(b) or 7.2 hereof respecting sale of the 
Shares, the inaccuracy of any representations made by such Purchaser herein 
or any statement or omission in any Prospectus that is corrected in any 
subsequent Prospectus that was delivered to the Purchaser prior to the 
pertinent sale or sales by the Purchaser.

           In addition to its other obligations under this paragraph (a), the 
Company agrees that, as an interim measure during the pendency of any claim, 
action, investigation, inquiry or other proceeding arising out of or based 
upon any statement or omission, or any alleged statement or omission, or any 
inaccuracy in the representations and warranties of the Company in this 
Agreement or failure to perform its obligations in this Agreement, all as 
described in this paragraph (a), it will reimburse each Purchaser on a 
quarterly basis for all reasonable legal or other expenses incurred in 
connection with investigating or defending any such claim, action, 
investigation, inquiry or other proceeding, notwithstanding the absence of a 
judicial determination as to the propriety and enforceability of the 
Company's obligation, to reimburse each Purchaser for such expenses and the 
possibility that such payments might later be held to have been improper by a 
court of competent jurisdiction.  To the extent that any such interim 
reimbursement payment is so held to have been improper, each Purchaser shall 
promptly return it to the Company together with interest, compounded daily, 
determined on the basis of the Prime Rate (or other commercial lending rate 
for borrowers of the highest credit standing) announced from time to time by 
Bank of America National Trust and Savings Association, San Francisco, 
California (the "Prime Rate").  Any such interim reimbursement payments which 
are not made to a Purchaser within 30 days of a request for reimbursement 
shall bear interest at the Prime Rate from the date of such request.  This 
indemnity agreement will be in addition to any liability which the Company 
may otherwise have.

           (b)  Each Purchaser will severally indemnify and hold harmless the 
Company, each of its directors, each of its officers who signed the 
Registration Statement and each person, if any, who controls the Company 
within the meaning of the Securities Act, against any losses, claims, 
damages, liabilities or expenses to which the Company, each of its directors, 
each of its officers who signed the Registration Statement or controlling 
person may become subject, under the Securities Act, the Exchange Act, or any 
other federal or state statutory law or regulation, or at

                                 -13-



common law or otherwise (including in settlement of any litigation, if such 
settlement is effected with the written consent of such Purchaser) insofar as 
such losses, claims, damages, liabilities or expenses (or actions in respect 
thereof as contemplated below) arise out of or are based upon any failure to 
comply with the covenants and agreements contained in Sections 5(b) or 7.2 
hereof respecting the sale of the Shares, the inaccuracy of any 
representation made by such Purchaser herein or any untrue or alleged untrue 
statement of any material fact contained in the Registration Statement, the 
Prospectus, or any amendment or supplement thereto, or arise out of or are 
based upon the omission or alleged omission to state therein a material fact 
required to be stated therein or necessary to make the statements therein not 
misleading, in each case to the extent, but only to the extent, that such 
untrue statement or alleged untrue statement or omission or alleged omission 
was made in the Registration Statement, the Prospectus, or any amendment or 
supplement thereto, in reliance upon and in conformity with written 
information furnished to the Company by or on behalf of any Purchaser 
expressly for use therein, and will reimburse the Company, each of its 
directors, each of its officers who signed the Registration Statement or 
controlling person for any legal and other expense reasonably incurred by the 
Company, each of its directors, each of its officers who signed the 
Registration Statement or controlling person in connection with 
investigating, defending, settling, compromising or paying any such loss, 
claim, damage, liability, expense or action.  In addition to its other 
obligations under this paragraph (b), each Purchaser severally agrees that, 
as an interim measure during the pendency of any claim, action, 
investigation, inquiry or other proceeding arising out of or based upon any 
failure to comply, statement or omission, or any alleged failure to comply, 
statement or omission, described in this paragraph (b) which relates to 
written information furnished to the Company by or on behalf of any 
Purchaser, it will reimburse the Company (and, to the extent applicable, each 
officer, director or controlling person) on a quarterly basis for all 
reasonable legal or other expenses incurred in connection with investigating 
or defending any such claim, action, investigation, inquiry or other 
proceeding, notwithstanding the absence of a judicial determination as to the 
propriety and enforceability of the Purchaser's obligations to reimburse the 
Company (and, to the extent applicable, each officer, director or controlling 
person) for such expenses and the possibility that such payments might later 
be held to have been improper by a court of competent jurisdiction.  To the 
extent that any such interim reimbursement payment is so held to have been 
improper, the Company (and, to the extent applicable, each officer, director 
or controlling person) shall promptly return it to such Purchaser together 
with interest, compounded daily, determined on the basis of the Prime Rate.  
Any such interim reimbursement payments which are not made to the Company 
within 30 days of a request for reimbursement shall bear interest

                                -14-



at the Prime Rate from the date of such request.  This indemnity agreement 
will be in addition to any liability which such Purchaser may otherwise have.

    (c)  Promptly after receipt by an indemnified party under this Section 
7.3        of notice of the commencement of any action, such indemnified 
party will, if a claim in respect thereof is to be made against an 
indemnifying party under this Section 7.3 notify the indemnifying party in 
writing of the commencement thereof; but the omission so to notify the 
indemnifying party will not relieve it from any liability which it may have 
to any indemnified party for contribution or otherwise than under the 
indemnity agreement contained in this Section 7.3 or to the extent it is not 
prejudiced as a proximate result of such failure.  In case any such action is 
brought against any indemnified party and such indemnified party seeks or 
intends to seek indemnity from an indemnifying party, the indemnifying party 
will be entitled to participate in, and, to the extent that it may wish, 
jointly with all other indemnifying parties similarly notified, to assume the 
defense thereof with counsel reasonably satisfactory to such indemnified 
party; provided, however, if the defendants in any such action include both 
the indemnified party and the indemnifying party and the indemnified party 
shall have reasonably concluded that there may be a conflict between the 
positions of the indemnifying party and the indemnified party in conducting 
the defense of any such action or that there may be legal defenses available 
to it and/or other indemnified parties which are different from or additional 
to those available to the indemnifying party, the indemnified party or 
parties shall have the right to select separate counsel to assume such legal 
defenses and to otherwise participate in the defense of such action on behalf 
of such indemnified party or parties.  Upon receipt of notice from the 
indemnifying party to such indemnified party of its election so to assume the 
defense of such action and approval by the indemnified party of counsel, the 
indemnifying party will not be liable to such indemnified party under this 
Section 7.3 for any legal or other expenses subsequently incurred by such 
indemnified party in connection with the defense thereof unless (i) the 
indemnified party shall have employed such counsel in connection with the 
assumption of legal defenses in accordance with the proviso to the preceding 
sentence (it being understood, however, that the indemnifying party shall not 
be liable for the expenses of more than one separate counsel, approved by 
such indemnifying party in the case of paragraph (a), representing the 
indemnified parties who are parties to such action) or (ii) the indemnified 
party shall not have employed counsel reasonably satisfactory to the 
indemnified party to represent the indemnified party within a reasonable time 
after notice of commencement of action, in each of which cases the fees and 
expenses of counsel shall be at the expense of the indemnifying party.

                                -15-



           (d)  If the indemnification provided for in this Section 7.3 is 
required by its terms but is for any reason held to be unavailable to or 
otherwise insufficient to hold harmless an indemnified party under paragraphs 
(a), (b) or (c) of this Section 7.3 in respect to any losses, claims, 
damages, liabilities or expenses referred to herein, then each applicable 
indemnifying party shall contribute to the amount paid or payable by such 
indemnified party as a result of any losses, claims, damages, liabilities or 
expenses referred to herein (i) in such proportion as is appropriate to 
reflect the relative benefits received by the Company and the Purchaser from 
the placement of Common Stock or (ii) if the allocation provided by clause 
(i) above is not permitted by applicable law, in such proportion as is 
appropriate to reflect not only the relative benefits referred to in clause 
(i) above but the relative fault of the Company and the Purchaser in 
connection with the statements or omissions or inaccuracies in the 
representations and warranties in this Agreement which resulted in such 
losses, claims, damages, liabilities or expenses, as well as any other 
relevant equitable considerations.  The respective relative benefits received 
by the Company on the one hand and each Purchaser on the other shall be 
deemed to be in the same proportion as the amount paid by such Purchaser to 
the Company pursuant to this Agreement for the Shares purchased by such 
Purchaser that were sold pursuant to the Registration Statement bears to the 
difference (the "Difference") between the amount such Purchaser paid for the 
Shares that were sold pursuant to the Registration Statement and the amount 
received by such Purchaser from such sale.  The relative fault of such 
Selling Shareholders and each Purchaser shall be determined by reference to, 
among other things, whether the untrue or alleged statement of a material 
fact or the omission or alleged omission to state a material fact or the 
inaccurate or the alleged inaccurate representation and/or warranty relates 
to information supplied by the Company or by such Purchaser and the parties' 
relative intent, knowledge, access to information and opportunity to correct 
or prevent such statement or omission. The amount paid or payable by a party 
as a result of the losses, claims, damages, liabilities and expenses referred 
to above shall be deemed to include, subject to the limitations set forth in 
paragraph (c) of this Section 7.3 any legal or other fees or expenses 
reasonably incurred by such party in connection with investigating or 
defending any action or claim.  The provisions set forth in paragraph (c) of 
this Section 7.3 with respect to notice of commencement of any action shall 
apply if a claim for contribution is to be made under this paragraph (d); 
PROVIDED, HOWEVER, that no additional notice shall be required with respect 
to any action for which notice has been give under paragraph (c) for purposes 
of indemnification.  The Company and each Purchaser agree that it would not 
be just and equitable if contribution pursuant to this Section 7.3 were 
determined solely by pro rata allocation (even if the Purchaser were treated 
as one entity for such purpose) or by any other method of allocation which 
does not

                                -16-



take account of the equitable considerations referred to in this paragraph.  
Notwithstanding the provisions of this Section 7.3, no Purchaser shall be 
required to contribute any amount in excess of the amount by which the 
Difference exceeds the amount of any damages that such Purchaser has 
otherwise been required to pay by reason of such untrue or alleged untrue 
statement or omission or alleged omission.  No person guilty of fraudulent 
misrepresentation (within the meaning of Section 11(f) of the Securities Act) 
shall be entitled to contribution from any person who was not guilty of such 
fraudulent misrepresentation.  The Purchasers' obligations to contribute 
pursuant to this Section 7.3 are several and not joint.

           (e)  It is agreed that any controversy arising out of the 
operation of the interim reimbursement arrangements set forth in paragraphs 
(a) and (b) of this Section 7.3, including the amounts of any requested 
reimbursement payments and the method of determining such amounts, shall be 
settled by arbitration conducted under the provisions of the Constitution and 
Rules of the Board of Governors of The New York Stock Exchange, Inc.  Any 
such arbitration must be commenced by service of a written demand for 
arbitration or a written notice of intention to arbitrate, therein electing 
the arbitration tribunal.  In the event the party demanding arbitration does 
not make such designation of any arbitration tribunal in such demand or 
notice, then the party responding to said demand or notice is authorized to 
do so.  Such an arbitration would be limited to the operation of the interim 
reimbursement provisions contained in paragraphs (a) and (b) of this Section 
7.3 and would not resolve the ultimate propriety or enforceability of the 
obligation to reimburse expenses which is created by the provisions of such 
paragraphs (a) and (b).

           7.4. TERMINATION OF CONDITIONS AND OBLIGATIONS.  The conditions 
precedent imposed by Section 5 or this Section 7 upon the transferability of 
the Shares shall cease and terminate as to any particular number of the 
Shares when such Shares shall have been effectively registered under the 
Securities Act and sold or otherwise disposed of in accordance with the 
intended method of disposition set forth in the Registration Statement 
covering such Shares or at such time as an opinion of counsel satisfactory to 
the Company shall have been rendered to the effect that such conditions are 
not necessary in order to comply with the Securities Act. 

           7.5. INFORMATION AVAILABLE.  So long as the Registration Statement 
is effective covering the resale of Shares owned by the Purchaser, the 
Company will furnish to the Purchaser: 

           (a)  as soon as practicable after available 
                (but in the case of the Company's Annual Report to 
                Shareholders, within 120 days after the end of each 
                fiscal year of the Company), one copy of (i)

                                -17-


                its Annual Report to Shareholders (which Annual Report shall
                contain financial statements audited in accordance with 
                generally accepted accounting principles by a national firm of
                certified public accountants), (ii) if not included in 
                substance in the Annual Report to Shareholders, its 
                Annual Report on Form 10-K, (iii) if not included in 
                substance in its Quarterly Reports to Shareholders, its 
                quarterly reports on Form 10-Q, and (iv) a full copy of 
                the particular Registration Statement covering the Shares 
                (the foregoing, in each case, excluding exhibits); 

           (b)  upon the reasonable request of the Purchaser, a 
                reasonable number of copies of the prospectuses to supply 
                to any other party requiring such prospectuses; 

and the Company, upon the reasonable request of the Purchaser, will meet with
the Purchaser or a representative thereof at the Company's headquarters to
discuss all information relevant for disclosure in the Registration Statement
covering the Shares subject to appropriate confidentiality limitations. 

           SECTION 8.  BROKER'S FEE.  The Purchaser acknowledges that the 
Company intends to pay to the Placement Agent a fee in respect of the sale of 
the Shares to the Purchaser.  Each of the parties hereto hereby represents 
that, on the basis of any actions and agreements by it, there are no other 
brokers or finders entitled to compensation in connection with the sale of 
the Shares to the Purchaser.

           SECTION 9.  NOTICES.  All notices, requests, consents and other 
communications hereunder shall be in writing, shall be mailed by first-class 
registered or certified airmail, or nationally recognized overnight express 
courier postage prepaid, and shall be deemed given when so mailed and shall 
be delivered as addressed as follows: 

           (a)  if to the Company, to:

                    Inhale Therapeutic Systems 
                    1060 East Meadow Circle
                    Palo Alto, California  94303
                    Attention: President 

                                -18-




            with a copy so mailed to:

                    Cooley Godward LLP
                    3000 Sand Hill Road
                    Building 3, Suite 230
                    Menlo Park, California  94025
                    Attn:  Mark P. Tanoury, Esq.
             
                or to such other person at such other place as the Company shall
                designate to the Purchaser in writing;

           (b)  if to the Purchaser, at its address as 
                set forth at the end of this Agreement, or at such other 
                address or addresses as may have been furnished to the 
                Company in writing; and

           SECTION 10.  CHANGES.  This Agreement may not be modified or 
amended except pursuant to an instrument in writing signed by the Company and 
the Purchaser.

           SECTION 11.  HEADINGS.  The headings of the various sections of 
this Agreement have been inserted for convenience of reference only and shall 
not be deemed to be part of this Agreement. 

           SECTION 12.   SEVERABILITY.  In case any provision contained in 
this Agreement should be invalid, illegal or unenforceable in any respect, 
the validity, legality and enforceability of the remaining provisions 
contained herein shall not in any way be affected or impaired thereby. 

           SECTION 13.  GOVERNING LAW.  This Agreement shall be governed by 
and construed in accordance with the laws of the State of New York and the 
federal law of the United States of America. 

           SECTION 14.  COUNTERPARTS.  This Agreement may be executed in two 
or more counterparts, each of which shall constitute an original, but all of 
which, when taken together, shall constitute but one instrument, and shall 
become effective when one or more counterparts have been signed by each party 
hereto and delivered to the other parties.

                               -19-



           IN WITNESS WHEREOF, the parties hereto have caused this Agreement 
to be executed by their duly authorized representatives as of the day and 
year first above written. 

                                  INHALE THERAPEUTIC SYSTEMS
    

                                  By_________________________________


Print or Type:

                                  Name of Purchaser
                                     (Individual or Institution):
                                    _________________________________

 
                                  Name of Individual representing
                                     Purchaser (if an Institution):
                                    _________________________________


                                  Title of Individual representing
                                     Purchaser (if an Institution):
                                    _________________________________

Signature by:

                                  Individual Purchaser or Individual
                                     representing Purchaser:
                                    _________________________________

                                  Address:___________________________

                                  Telephone:_________________________

                                  Telecopier:________________________


                               -20-



                       SUMMARY INSTRUCTION SHEET FOR PURCHASER

                      (to be read in conjunction with the entire
                          Purchase Agreement which follows)


A.  Complete the following items on BOTH Purchase Agreements:

    1.   Page 20 - Signature:
                  
         (i)  Name of Purchaser (Individual or Institution)

        (ii)  Name of Individual representing Purchaser (if an Institution)

       (iii)  Title of Individual representing Purchaser (if an Institution)

        (iv)  Signature of Individual Purchaser or Individual representing
              Purchaser

    2.   Appendix I - Stock Certificate Questionnaire:

         Provide the information requested by the Stock Certificate
         Questionnaire.

         Appendix I - Registration Statement Questionnaire:

         Provide the information requested by the Registration Statement
         Questionnaire.

    3.   Return BOTH properly completed and signed Purchase Agreements
         including the properly completed Appendix I to:

         Vector Securities International, Inc.
         Suite 350
         1751 Lake Cook Road
         Deerfield, Illinois  60015
         Attn: Marina S. Bozilenko

B.  Instructions regarding the transfer of funds for the purchase of Shares
    will be sent by facsimile to the Purchaser by the Placement Agents at a
    later date.

C.  Upon the resale of the Shares by the Purchasers after the Registration
    Statement covering the Shares is effective, as described in the Purchase
    Agreement, the Purchaser:

         (i)  must deliver a current prospectus of the Company to the buyer
              (prospectuses must be obtained from the Company at the
              Purchaser's request); and



        (ii)  must send a letter in the form of Appendix II to the Company so
              that the Shares may be properly transferred.



                                                                  Appendix I
                                                               (one of two)


INHALE THERAPEUTIC SYSTEMS

STOCK CERTIFICATE QUESTIONNAIRE



    Pursuant to Section 3 of the Agreement, please provide us with the
following information: 

1.  The exact name that your Shares are to be registered in (this is the name
    that will appear on your stock certificate(s)).  You may use a nominee name
    if appropriate:                                     _______________________ 

2.  The relationship between the Purchaser of the Shares and the Registered
    Holder listed in response to item 1 above:           ______________________ 

3.  The mailing address of the Registered Holder listed in
    response to item 1 above:                            ______________________ 

                                                         ______________________ 

                                                         ______________________ 

                                                         ______________________ 

4.  The Social Security Number or Tax Identification Number of the Registered
    Holder listed in response to item 1 above:           ______________________ 


                                                                    Appendix I 
                                                                   (two of two)

                                           
                              INHALE THERAPEUTIC SYSTEMS
                         REGISTRATION STATEMENT QUESTIONNAIRE


           In connection with the preparation of the Registration Statement, 
please provide us with the following information:

           1.   Pursuant to the "Selling Shareholder" section of the 
Registration Statement, please state your or your organization's name exactly 
as it should appear in the Registration Statement:

           2.  Please provide the number of shares that you or your 
organization will own immediately after Closing, including those Shares 
purchased by you or your organization pursuant to this Purchase Agreement and 
those shares purchased by you or your organization through other 
transactions:  

           3.   Have you or your organization had any position, office or 
other material relationship within the past three years with the Company or 
its affiliates other than as disclosed in the Prospectus included in the 
Registration Statement? 

                       _____ Yes         _____ No 

           If yes, please indicate the nature of any such relationships below: 

 _________________________________________________________________ 

 _________________________________________________________________ 
                                                                    
 _________________________________________________________________ 




                                                                   APPENDIX II



Attention:

                      PURCHASER'S CERTIFICATE OF SUBSEQUENT SALE

    The undersigned, [an officer of, or other person duly author-

ized by] _____________________________________________________________
               [fill in official name of individual or institution]

hereby certifies that he/she [said institution] is the Purchaser of
the shares evidenced by the attached certificate, and as such,
sold such shares on____________________in accordance with
                          [date]

Registration Statement number ________________________________________
                               [fill in the number of or otherwise

________________________________ and the requirement of delivering a
identify Registration Statement]

current prospectus by the Company has been complied with in connection with such
sale. 

Print or Type: 

    Name of Purchaser
            (Individual or
             Institution):       ______________________

          Name of Individual
            representing
            Purchaser (if an
            Institution)         ______________________

          Title of Individual
            representing
            Purchaser (if an
            Institution):        ______________________

Signature by:

          Individual Purchaser
            or Individual repre-
            senting Purchaser:   ______________________