EXHIBIT 11.1 CYGNUS, INC. STATEMENT REGARDING COMPUTATION OF LOSS PER SHARE (IN THOUSANDS, EXCEPT PER SHARE DATA) YEAR ENDED DECEMBER 31, ---------------------------------- 1996 1995 1994 ---------- ---------- ---------- Primary and fully diluted: Weighted average of common shares outstanding during the period............. 18,544 16,265 13,947 ---------- ---------- ---------- Shares used in computation of net loss per share.............................. 18,544 16,265 13,947 ---------- ---------- ---------- ---------- ---------- ---------- Net loss...................................................................... $ (11,052) $ (12,842) $ (17,360) ---------- ---------- ---------- ---------- ---------- ---------- Net loss per share............................................................ $ (0.60) $ (0.79) $ (1.24) ---------- ---------- ---------- ---------- ---------- ---------- 31