FORM OF
                                                                 EXHIBIT 10.15



                        APOLLO BIOPHARMACEUTICS, INC.


                                    AND


                  AMERICAN STOCK TRANSFER AND TRUST COMPANY


                                          

                             WARRANT AGREEMENT



                         Dated as of May __, 1997




 
          WARRANT AGREEMENT, dated the ___ day of May, 1997 (this 
"Agreement"), between Apollo BioPharmaceutics, Inc., a Delaware corporation 
(the "Company"), and American Stock Transfer and Trust Company, a Delaware 
corporation, as Warrant Agent (the "Warrant Agent").

                          W I T N E S E T H:

          WHEREAS, in connection with (i) the offering to the public by the 
Company (the "Public Offering") of up to 500,000 units (the "Units"), each 
Unit consisting of two shares of the Company's Common Stock (as defined 
below), $0.02 par value per share (the "Common Stock"), and one redeemable 
warrant, each such redeemable warrant entitling the registered holder thereof 
to purchase one share of Common Stock upon the terms and subject to the 
conditions set forth in this Agreement (collectively, the "Redeemable 
Warrants"), (ii) the over-allotment option to purchase up to an additional 
75,000 Units (the "Over-Allotment Option"), and (iii) the sale to Neidiger/ 
Tucker/ Bruner, Inc. and Westport Resources Investment Services, Inc., and 
their respective successors and assigns (collectively, the "Representatives") 
of warrants (the "Representatives' Warrants") to purchase up to 50,000 Units, 
the Company will issue up to 625,000 Redeemable Warrants; and

          WHEREAS, the Company desires to provide for the issuance of 
certificates representing the Redeemable Warrants; and

          WHEREAS, the Company desires the Warrant Agent to act on behalf of 
the Company, and the Warrant Agent is willing to so act, in connection with 
the issuance, registration, transfer and exchange of certificates 
representing the Redeemable Warrants and the exercise of the Redeemable 
Warrants.

          NOW, THEREFORE, in consideration of the premises and the mutual 
agreements hereinafter set forth and for the purpose of defining the terms 
and provisions of the Redeemable Warrants and the certificates representing 
the Redeemable Warrants and the respective rights and obligations thereunder 
of the Company, the Representatives, the holders of certificates representing 
the Redeemable Warrants and the Warrant Agent, the parties hereto agree as 
follows:

          SECTION 1. DEFINITIONS.  As used herein, the following terms shall 
have the following meanings:

          (a)  "Securities Act" shall mean the Securities Act of 1933, as 
amended.

          (b)  "Business Day" shall mean any day other than a Saturday or 
Sunday on which banks in The City of New York  are not authorized or required 
to close.

          (c)  "Change of Shares" shall have the meaning ascribed to it in 
Section 8(a)(i).

          (d)  "Commission" shall mean the Securities and Exchange Commission.

                                      1



          (e)  "Convertible Securities" shall have the meaning ascribed to it 
in Section 8(b).

          (f)  "Corporate Office" shall mean the office of the Warrant Agent 
(or its successor) at which at any particular time its principal business in 
New York, New York shall be administered, which office is located on the date 
hereof at 40 Wall Street, New York, New York 10005.

          (g)  "Current Market Price" per share of Common Stock on any date 
herein specified shall mean the average of the highest quoted daily closing 
prices of the Common Stock for the ten Trading Days preceding such date.  The 
closing price of the Common Stock on each Trading Day shall be (A) the 
average closing sale price for the Common Stock in the over-the- counter 
market as reported by the National Association of Securities Dealers 
Automated Quotation System or (B) the closing sale price on the primary 
exchange on which the Common Stock is traded, if the Common Stock is traded 
on a national securities exchange.

          (h)  "Exchange Act" shall mean the Securities Exchange Act of 1934, 
as amended.

          (i)  "Exercise Date" shall mean, subject to the provisions of 
Section 5(b) hereof, as to any Redeemable Warrant, the date on which the 
Warrant Agent shall have received both (i) the Warrant Certificate 
representing such Redeemable Warrant, with the exercise form thereon duly 
executed by the Registered Holder thereof or his attorney duly authorized in 
writing, and (ii) payment in cash or by certified or bank check made payable 
to the Company, of the amount in lawful money of the United States of America 
equal to the applicable Exercise Price.

          (j)  "Exercise Price" shall mean, with respect to any Redeemable 
Warrant, the purchase price per share of Common Stock that must be paid to 
the Company as a condition precedent to the exercise of such Redeemable 
Warrant, which amount shall initially be, subject to modification and 
adjustment as provided in Section 8 hereof, $6.50 per share and further 
subject, to the Company's right, in its sole discretion, to decrease the 
Exercise Price for a period of not less than 30 days on not less than 30 
days' prior written notice to the Registered Holders and the Representatives.

          (k)  "Initial Warrant Exercise Date" shall mean, with respect to 
the Redeemable Warrants, May __, 1997 (the date of the Prospectus).

          (l)  "Initial Warrant Redemption Date" shall mean, with respect to 
the Redeemable Warrants, May __, 1998 (12 months from the date of the 
Prospectus).

          (m)  "Redemption Date" shall mean with respect to any Redeemable 
Warrant, the date on which such Redeemable Warrant will be redeemed, as set 
forth in a notice given with respect to such Redeemable Warrants pursuant to 
Section 9.

          (n)  "Redemption Price" shall mean $0.25 per Redeemable Warrant.

                                      2



          (o)  "Registered Holder" shall mean the person in whose name any 
certificate representing the Redeemable Warrants shall be registered on the 
books maintained by the Warrant Agent pursuant to Section 6 hereof.

          (p)  "Subsidiary" or "Subsidiaries" shall mean any corporation or 
corporations, as the case may be, of which stock having ordinary power to 
elect a majority of the Board of Directors of such corporation (regardless of 
whether or not at the time stock of any other class or classes of such 
corporation shall have or may have voting power by reason of the happening of 
any contingency) is at the time directly or indirectly owned by the Company 
or by one or more Subsidiaries, or by the Company and one or more 
Subsidiaries.

          (q)  "Trading Day" shall mean any day other than a Saturday or 
Sunday on which the principal market on which Common Stock is traded is open 
for trading.

          (r)  "Transfer Agent" shall mean American Stock Transfer and Trust 
Company, New York, New York, or its authorized successor.

          (s)  "Underwriting Agreement" shall mean the underwriting agreement 
dated May __, 1997 (the date of the Prospectus) between the Company and the 
Representatives, as representative of the several underwriters, relating to 
the purchase for resale to the public of shares of Common Stock and 
Redeemable Warrants.

          (t)  "Warrant Agent" shall have the meaning specified in the 
introduction. 

          (u)  "Warrant Certificates" shall mean in the case of Redeemable 
Warrants, certificates representing each of the Redeemable Warrants 
substantially in the form annexed hereto as Exhibit A.

          (v)  "Warrant Expiration Date" shall mean, with respect to the 
Redeemable Warrants, 5:00 p.m. (New York time) on May __, 2002, or, if such 
date shall not be a Business Day, then 5:00 p.m. (New York time) on the next 
following Business Day, subject to the Company's right, prior to the Warrant 
Expiration Date, in its sole discretion, to extend such Warrant Expiration 
Date on five Business Days' prior written notice to the Registered Holders.

          SECTION 2. REDEEMABLE WARRANTS AND ISSUANCE OF WARRANT 
CERTIFICATES.  (a) One Redeemable Warrant shall initially entitle the 
Registered Holder of the Warrant Certificate representing such Redeemable 
Warrant to purchase at the Exercise Price therefor from the Initial Warrant 
Exercise Date until the Warrant Expiration Date, one share of Common Stock 
upon the exercise thereof, subject to modification and adjustment as provided 
in Section 8 hereof.

          (b)  Upon execution of this Agreement, Warrant Certificates 
representing 500,000 Redeemable Warrants to purchase up to an aggregate of 
500,000 shares of Common Stock (subject to modification and adjustment as 
provided in Section 8 hereof) shall be executed by the Company and delivered 
to the Warrant Agent.

                                      3



          (c)  Upon exercise of the Over-Allotment Option, in whole or in 
part, Warrant Certificates representing up to 75,000 Redeemable Warrants to 
purchase up to an aggregate of 75,000 shares of Common Stock (subject to 
modification and adjustment as provided in Section 8) shall be executed by 
the Company and delivered to the Warrant Agent.

          (c)  Upon exercise of the Representatives' Warrant, in whole or in 
part, Warrant Certificates representing up to 50,000 Redeemable Warrants to 
purchase up to an aggregate of 50,000 shares of Common Stock (subject to 
modification and adjustment as provided in Section 8) shall be executed by 
the Company and delivered to the Warrant Agent.

          (d)  From time to time, up to the Warrant Expiration Date, as the 
case may be, the Warrant Agent shall countersign and deliver Warrant 
Certificates in required denominations of one or whole number multiples 
thereof to the person entitled thereto in connection with any transfer or 
exchange permitted under this Agreement.  No Warrant Certificates shall be 
issued except (i) Warrant Certificates initially issued hereunder, (ii) 
Warrant Certificates issued upon any transfer or exchange of Warrants, (iii) 
Warrant Certificates issued in replacement of lost, stolen, destroyed or 
mutilated Warrant Certificates pursuant to Section 7 hereof and (iv) at the 
option of the Company, Warrant Certificates in such form as may be approved 
by its Board of Directors, to reflect any adjustment or change in the 
Exercise Price, the number of shares of Common Stock purchasable upon 
exercise of the Redeemable Warrants or the Redemption Price therefor made 
pursuant to Section 8 hereof.

          SECTION 3.  FORM AND EXECUTION OF WARRANT CERTIFICATES. (a) The 
Warrant Certificates representing Redeemable Warrants shall be substantially 
in the form annexed hereto as EXHIBIT A (the provisions of which are hereby 
incorporated herein).  All of such Warrant Certificates may have such 
letters, numbers or other marks of identification or designation and such 
legends, summaries or endorsements printed, lithographed or engraved thereon 
as the Company may deem appropriate and as are not inconsistent with the 
provisions of this Agreement, or as may be required to comply with any law or 
with any rule or regulation made pursuant thereto or with any rule or 
regulation of any stock exchange on which the Redeemable Warrants may be 
listed, or to conform to usage.  The Warrant Certificates shall be dated the 
date of issuance thereof (whether upon initial issuance, transfer, exchange 
or in lieu of mutilated, lost, stolen or destroyed Warrant Certificates).

          (b)  Warrant Certificates shall be executed on behalf of the 
Company by its Chairman of the Board, President or any Vice President and by 
its Treasurer or an Assistant Treasurer or its Secretary or an Assistant 
Secretary, by manual signatures or by facsimile signatures printed thereon, 
and shall have imprinted thereon a facsimile of the Company's seal.  Warrant 
Certificates shall be manually countersigned by the Warrant Agent and shall 
not be valid for any purpose unless so countersigned.  In case any officer of 
the Company who shall have signed any of the Warrant Certificates shall cease 
to be such officer of the Company before the date of issuance of the Warrant 
Certificates or before countersignature by the Warrant Agent and issue and 
delivery thereof, such Warrant Certificates, nevertheless, may be 
countersigned by the Warrant Agent, issued and delivered with the same force 
and effect as though the person who signed such Warrant Certificates had not 
ceased to be such officer of the Company.

                                      4




          SECTION 4. EXERCISE. (a) Redeemable Warrants in denominations of 
one or whole number multiples thereof may be exercised commencing at any time 
on or after the Initial Warrant Exercise Date, but not after the Warrant 
Expiration Date, upon the terms and subject to the conditions set forth 
herein (including the provisions set forth in Sections 5 and 9 hereof) and in 
the applicable Warrant Certificate.  A Redeemable Warrant shall be deemed to 
have been exercised immediately prior to the close of business on the 
Exercise Date, PROVIDED that the Warrant Certificate representing such 
Redeemable Warrant, with the exercise form thereon duly executed by the 
Registered Holder thereof or his attorney duly authorized in writing, 
together with payment in cash or by certified or bank check made payable to 
the Company, of an amount in lawful money of the United States of America 
equal to the applicable Exercise Price has been received in good funds by the 
Warrant Agent.  The person entitled to receive the securities deliverable 
upon such exercise shall be treated for all purposes as the holder of such 
securities as of the close of business on the Exercise Date.  If Redeemable 
Warrants in denominations other than one or whole number multiples thereof 
shall be exercised at one time by the same Registered Holder, the number of 
full shares of Common Stock or Units, as the case may be, which shall be 
issuable upon exercise thereof shall be computed on the basis of the 
aggregate number of full shares of Common Stock or Units, as the case may be, 
issuable upon such exercise.  As soon as practicable on or after the Exercise 
Date and in any event within five Business Days after such date, if one or 
more Redeemable Warrants have been exercised, the Warrant Agent on behalf of 
the Company shall cause to be issued to the person or persons entitled to 
receive the same a Common Stock certificate or certificates for the shares of 
Common Stock or Units, as the case may be, deliverable upon such exercise, 
and the Warrant Agent shall deliver the same to the person or persons 
entitled thereto. Upon the exercise of any one or more Redeemable Warrants, 
the Warrant Agent shall promptly notify the Company in writing of such fact 
and of the number of securities delivered upon such exercise and, subject to 
subsection (b) below, shall cause all payments of an amount, in cash or by 
check made payable to the order of the Company, equal to the Exercise Price 
for such Redeemable Warrants less any amount payable to the Representatives 
under Section 4(b) below, to be deposited promptly in the Company's bank 
account.

          (b)  At any time upon the exercise of any one or more Redeemable 
Warrants occurring on or after the first anniversary of the Initial Warrant 
Exercise Date, the Warrant Agent shall, on a daily basis, within five 
Business Days after such exercise, notify the Representatives, its successors 
or assigns of the exercise of any such Redeemable Warrants and shall, on a 
weekly basis (subject to collection of funds constituting the tendered 
Exercise Price, but in no event later than five Business Days after the last 
day of the calendar week in which such funds were tendered), remit to the 
Representatives an amount equal to five percent of the Exercise Price of such 
Redeemable Warrants being then exercised; PROVIDED, HOWEVER, that the Warrant 
Agent shall not be obligated to pay any amounts pursuant to this Section 4(b) 
during any week that such amounts payable are less than $1,000 and the 
Warrant Agent's obligation to make such payments to the Representatives shall 
be suspended until the amount payable aggregates $1,000; and PROVIDED, 
FURTHER, that, in any event, any such payment (regardless of amount) shall be 
made not less frequently than monthly; and provided, further, that such 
remittance to the Representatives shall not be made with respect to any 
exercise of any Redeemable Warrant (i) that has an Exercise Price greater 
than the Current Market Price on the date of exercise, (ii) if such 
Redeemable Warrant is held in a discretionary account at the time of exercise 
and prior specific

                                      5


approval for exercise is not received from the Registered Holder thereof, or 
(iii) if the exercise of such Redeemable Warrant was not solicited by the 
Representatives.

          (c)  The Company shall not be obligated to issue any fractional 
share interests or fractional warrant interests upon the exercise of any 
Redeemable Warrant or Redeemable Warrants, but instead shall pay cash in lieu 
of fractional interests based upon the current market value of any fractional 
shares.

          (d)  The Warrant Agent shall retain for a period of two years from 
the date of exercise any Warrant Certificate received by it upon such 
exercise.

          SECTION 5. RESERVATION OF SHARES; LISTING; PAYMENT OF TAXES; ETC.  
(a)  The Company covenants that it will at all times reserve and keep 
available out of its authorized Common Stock, solely for the purpose of issue 
upon exercise of Redeemable Warrants and conversion of the Units, such number 
of shares of Common Stock as shall then be issuable upon the exercise of all 
outstanding Redeemable Warrants.  The Company covenants that all shares of 
Common Stock which shall be issuable upon exercise of the Redeemable Warrants 
shall, at the time of delivery thereof against payment of the Exercise Price 
therefor, be duly and validly issued and fully paid and nonassessable and 
free from all preemptive or similar rights, taxes, liens and charges with 
respect to the issue thereof, and that upon issuance such shares shall be 
listed on each securities exchange or approved for quotation on any automated 
quotation system, if any, on which the other shares of outstanding Common 
Stock of the Company are then listed or quoted.

          (b)  The Company covenants that if any securities to be reserved 
for the purpose of exercise of Redeemable Warrants hereunder require 
registration with, or approval of, any governmental authority under any 
federal securities law before such securities may be validly issued or 
delivered upon such exercise, then the Company shall file a registration 
statement under the federal securities laws or a post-effective amendment, 
use its reasonable efforts to cause the same to become or remain effective 
and to keep such registration statement current while any of the Redeemable 
Warrants are outstanding, and deliver a prospectus which complies with 
Section 10(a)(3) of the Securities Act, to the Registered Holder exercising 
the Redeemable Warrant (except, if in the opinion of counsel to the Company, 
such registration is not required under the federal securities law or if the 
Company receives a letter from the staff of the Commission stating that it 
would not take any enforcement action if such registration is not effected).  
The Company will use its reasonable efforts to obtain appropriate approvals 
or registrations under state "blue sky" securities laws for the purpose of 
enabling the exercise of the Redeemable Warrants, provided, that the Company 
shall not be required to qualify as a foreign corporation or file a general 
or limited consent to service of process in any such jurisdiction, or to make 
any changes in its capital structure or in any other material aspect of its 
business or to enter into any material agreement with any state securities 
authority, including any agreements to escrow any shares of its capital 
stock. With respect to any such securities, however, Redeemable Warrants may 
not be exercised by, or shares of Common Stock issued to, any Registered 
Holder in any state in which such exercise would be unlawful.

                                      6


          (c)  The Company shall pay all documentary, stamp or similar taxes 
and other governmental charges that may be imposed with respect to the 
issuance of Redeemable Warrants, or the issuance or delivery of any shares of 
Common Stock upon exercise of the Redeemable Warrants; PROVIDED, HOWEVER, 
that if shares of Common Stock are to be delivered in a name other than the 
name of the Registered Holder of the Warrant Certificate representing any 
Redeemable Warrant being exercised, then no such delivery shall be made 
unless the person requesting the same has paid to the Warrant Agent the 
amount of transfer taxes or charges incident thereto, if any.

          (d)  The Warrant Agent is hereby irrevocably authorized as the 
Transfer Agent to requisition from time to time certificates representing 
shares of Common Stock or other securities required upon exercise of the 
Redeemable Warrants, and the Company will comply with all such requisitions.

          (e)  Prior to the exercise of any Redeemable Warrant, the 
Registered Holder thereof, as such, shall not be entitled to any rights of a 
stockholder of the Company, including without limitation the right to vote or 
to receive dividends or other distributions, and shall not be entitled to 
receive any notice of proceedings of the Company except as required by 
applicable law or provided herein and the Underwriting Agreement.

          SECTION 6. EXCHANGE AND REGISTRATION OF TRANSFER. (a) Warrant 
Certificates may be exchanged for other Warrant Certificates representing an 
equal aggregate number of Redeemable Warrants or may be transferred in whole 
or in part.  Warrant Certificates to be so exchanged shall be surrendered to 
the Warrant Agent at its Corporate Office, and the Company shall execute and 
the Warrant Agent shall countersign, issue and deliver in exchange therefor 
the Warrant Certificate or Certificates which the Registered Holder making 
the exchange shall be entitled to receive.

          (b)  The Warrant Agent shall keep, at such office, books in which, 
subject to such reasonable regulations as it may prescribe, it shall register 
Warrant Certificates and the transfer thereof. Upon due presentment for 
registration of transfer of any Warrant Certificate at such office, the 
Company shall execute and the Warrant Agent shall issue and deliver to the 
transferee or transferees a new Warrant Certificate or Certificates 
representing an equal aggregate number of Redeemable Warrants.

          (c)  With respect to any Warrant Certificates presented for 
registration of transfer, or for exchange or exercise, the assignment or 
exercise form, as the case may be, on the reverse thereof shall be duly 
endorsed or be accompanied by a written instrument or instruments of transfer 
and subscription, in form satisfactory to the Company and the Warrant Agent, 
duly executed by the Registered Holder thereof or the Registered Holder's 
agent duly authorized in writing.

          (d)  No service charge shall be made for any exchange or 
registration of transfer of Warrant Certificates. However, the Company may 
require payment of a sum sufficient to cover any tax or other governmental 
charge that may be imposed in connection therewith.

                                      7



          (e)  All Warrant Certificates surrendered for exercise or for 
exchange shall be promptly cancelled by the Warrant Agent.

          (f)  Prior to due presentment for registration or transfer thereof, 
the Company and the Warrant Agent may deem and treat the Registered Holder of 
any Warrant Certificate as the absolute owner thereof of each Redeemable 
Warrant represented thereby (notwithstanding any notations of ownership or 
writing thereon made) for all purposes and shall not be affected by any 
notice to the contrary.

          SECTION 7. LOSS OR MUTILATION. Upon receipt by the Company and the 
Warrant Agent of evidence satisfactory to them of the ownership of and the 
loss, theft, destruction or mutilation of any Warrant Certificate and (in the 
case of loss, theft or destruction) of indemnity satisfactory to them, and 
(in case of mutilation) upon surrender and cancellation thereof, the Company 
shall execute and the Warrant Agent shall countersign and deliver in lieu 
thereof a new Warrant Certificate representing an equal number of Redeemable 
Warrants.  Applicants for a substitute Warrant Certificate shall also comply 
with such other reasonable regulations and pay such other reasonable charges 
as the Warrant Agent may prescribe.

          SECTION 8.  ADJUSTMENT OF PURCHASE PRICE AND NUMBER OF SHARES OF 
COMMON STOCK.  (a) In case the Company shall at any time subdivide or combine 
the outstanding shares of Common Stock, the Exercise Price for Redeemable 
Warrants shall forthwith be proportionately decreased in the case of a 
subdivision or increased in the case of a combination.

          (b)  In case the Company shall pay a dividend in, or make a 
distribution of, shares of Common Stock or of the Company's capital stock 
convertible into shares of Common Stock, the Exercise Price for Redeemable 
Warrants shall forthwith be proportionately decreased.  An adjustment made 
pursuant to this Section 8(b) shall be made as of the record date for the 
subject stock dividend or distribution.

          (c)  In case of any reclassification or change of outstanding 
shares of Common Stock issuable upon exercise of the Redeemable Warrants 
(other than a change in par value, or from par value to no par value, or from 
no par value to par value or as a result of a subdivision or combination), or 
in case of any consolidation or merger of the Company with or into another 
corporation (other than a merger in which the Company is the continuing 
corporation and which does not result in any reclassification or change of 
the then outstanding shares of Common Stock or other capital stock issuable 
upon exercise of the Redeemable Warrants (other than a change in par value, 
or from par value to no par value, or from no par value to par value or as a 
result of subdivision or combination)) or in case of any sale or conveyance 
to another corporation of all or substantially all of the assets or property 
of the Company that is effected in such a way that holders of the securities 
issuable upon exercise of the Redeemable Warrants shall be entitled to 
receive securities or other property with respect to or in exchange for the 
securities issuable upon exercise of the Redeemable Warrants, then, as a 
condition of such reclassification, change, consolidation, merger, sale or 
conveyance, the Company, or such successor or purchasing corporation, as the 
case may be, shall make lawful and adequate provision whereby the Registered 
Holder of each Redeemable Warrant then outstanding shall have the right 
thereafter to receive on exercise of such Redeemable Warrant the kind and 
amount of securities and property receivable upon such reclassification, 
change, consolidation, merger, sale or conveyance, by a 

                                      8



holder of the number of securities issuable upon exercise of such Redeemable 
Warrant immediately prior to such reclassification, change, consolidation, 
merger, sale or conveyance and shall forthwith file at the Corporate Office 
of the Warrant Agent a statement signed by its President or a Vice President 
and by its Treasurer or an Assistant Treasurer or its Secretary or an 
Assistant Secretary evidencing such provision. The above provisions of this 
Section 8(c) shall similarly apply to successive reclassifications and 
changes of shares of Common Stock and to successive consolidations, mergers, 
sales or conveyances.

          (d)  Irrespective of any adjustments or changes in the Exercise 
Price or the number of shares of Common Stock purchasable upon exercise of 
the Redeemable Warrants, the Warrant Certificates theretofore and thereafter 
issued shall, unless the Company shall exercise its option to issue new 
Warrant Certificates pursuant to Section 2(e) hereof, continue to express the 
Exercise Price per share and the number of shares purchasable thereunder as 
the Exercise Price per share and the number of shares purchasable thereunder 
were expressed in the Warrant Certificates when the same were originally 
issued.

          (e)  After each adjustment of the Exercise Price pursuant to this 
Section 8, the Company will promptly prepare a certificate signed by the 
Chairman or President, and by the Treasurer or an Assistant Treasurer or the 
Secretary or an Assistant Secretary, of the Company setting forth: (i) the 
Exercise Price as so adjusted, (ii) the number of shares of Common Stock 
purchasable upon exercise of each Redeemable Warrant, after such adjustment, 
and (iii) a brief statement of the facts accounting for such adjustment. The 
Company will promptly file such certificate with the Warrant Agent and cause 
a brief summary thereof to be sent by ordinary first class mail to each 
Registered Holder at his last address as it shall appear on the registry 
books of the Warrant Agent. No failure to mail such notice nor any defect 
therein or in the mailing thereof shall affect the validity thereof except as 
to the holder to whom the Company failed to mail such notice, or except as to 
the holder whose notice was defective. The affidavit of an officer of the 
Warrant Agent or the Secretary or an Assistant Secretary of the Company that 
such notice has been mailed shall, in the absence of fraud, be prima facie 
evidence of the facts stated therein.

          (f)  Redeemable Warrant holders shall not be entitled to cash 
dividends paid by the Company prior to the exercise of any Redeemable Warrant 
or Warrants held by them.

          SECTION 9. REDEMPTION.

          (a)  Commencing on the Initial Warrant Redemption Date, the Company 
may, on not less than 30 days' prior written notice (which may be given 
before the Initial Warrant Redemption Date) redeem all or a portion (pro rata 
among all Registered Holders) of the Redeemable Warrants at the Redemption 
Price, PROVIDED, HOWEVER, that before any such call for redemption of 
Redeemable Warrants can take place, (A) the average closing sale price for 
the Common Stock in the over-the-counter market as reported by the National 
Association of Securities Dealers Automated Quotation System or (B) the 
closing sale price on the primary exchange on which the Common Stock is 
traded, if the Common Stock is traded on a national securities exchange, 
shall have for 20 consecutive Trading Days ending within ten days prior to 
the date on which the notice contemplated by (b) and (c) below is given, 
equaled or exceeded

                                       9


$10.00 per share (subject to adjustment in the event of any stock splits or 
other similar events as provide in Section 8 hereof).

          (b)  If the Company shall exercise its right to redeem any or all 
of the Redeemable Warrants, it shall give or cause to be given notice to the 
Registered Holders of the Redeemable Warrants, by mailing to such Registered 
Holders a notice of redemption, first class, postage prepaid, at their last 
address as shall appear on the records of the Warrant Agent. Any notice 
mailed in the manner provided herein shall be conclusively presumed to have 
been duly given in accordance with Section 12 whether or not the Registered 
Holder receives such notice. Not less than five Business Days prior to the 
mailing to the Registered Holders of the Redeemable Warrants of the notice of 
redemption, the Company shall deliver or cause to be delivered to the 
Representatives a similar notice telephonically and confirmed in writing 
together with a list of the Registered Holders (including their respective 
addresses and number of Redeemable Warrants beneficially owned) to whom such 
notice of redemption has been or will be given and the number of Redeemable 
Warrants to be redeemed from each such Registered Holder.

          (c)  The notice of redemption shall specify (i) the Redemption 
Price, (ii) the date fixed for redemption, which shall in no event be less 
then thirty (30) days after the date of mailing of such notice, (iii) the 
number of Redeemable Warrants to be redeemed from the recipient Registered 
Holder, (iv) the place where the Warrant Certificate shall be delivered and 
the Redemption Price shall be paid, and (v) that the right to exercise the 
Redeemable Warrants to which the notice of redemption applies shall terminate 
at 5:00 p.m. (New York time) on the Business Day immediately preceding the 
date fixed for redemption. No failure to mail such notice nor any defect 
therein or in the mailing thereof shall affect the validity of the 
proceedings for such redemption except as to a Registered Holder (a) to whom 
notice was not mailed or (b) whose notice was defective. An affidavit of the 
Warrant Agent or the Secretary or Assistant Secretary of the Company that 
notice of redemption has been mailed shall, in the absence of fraud, be prima 
facie evidence of the facts stated therein.

          (d)  Any right to exercise a Redeemable Warrant shall terminate at 
5:00 p.m. (New York time) on the Business Day immediately preceding the 
Redemption Date fixed for such Redeemable Warrant. The Redemption Price 
payable to the Registered Holders shall be mailed to such persons at their 
addresses of record.

          (e)  The Company shall indemnify the Representatives and each 
person, if any, who controls the Representatives within the meaning of 
Section 15 of the Securities Act or Section 20(a) of the Exchange Act against 
all loss, claim, damage, expense or liability (including all expenses 
reasonably incurred in investigating, preparing or defending against any 
claim whatsoever) to which any of them may become subject under the 
Securities Act, the Exchange Act or otherwise, arising from the registration 
statement or prospectus referred to in Section 5(b) hereof to the same extent 
and with the same effect (including the provisions regarding contribution) as 
the provisions pursuant to which the Company has agreed to indemnify the 
Representatives contained in Section 7 of the Underwriting Agreement.

                                      10



          (f)  If and to the extent reasonably requested by the 
Representatives, five Business Days prior to the Redemption Date, the Company 
shall furnish to the Representatives (i) an opinion of counsel to the 
Company, dated such date and addressed to the Representatives, and (ii) a 
"cold comfort" letter dated such date addressed to the Representatives, 
signed by the independent public accountants who have issued a report on the 
Company's financial statements included in the registration statement, if 
any, of the Company in connection with such redemption, in each case covering 
substantially the same matters with respect to such registration statement 
(and the prospectus included therein) and, in the case of such accountants' 
letter, with respect to events subsequent to the date of such financial 
statements, as are customarily covered in opinions of issuer's counsel and in 
accountants' letters delivered to underwriters in underwritten public 
offerings of securities, including, without limitation, those matters covered 
in Sections 6(k) and (l) of the Underwriting Agreement.

          (g)  The Company shall as soon as practicable after the Redemption 
Date, and in any event within 15 months thereafter, make "generally available 
to its security holders" (within the meaning of Rule 158 under the Securities 
Act) an earnings statement (which need not be audited) complying with Section 
11(a) of the Securities Act and covering a period of at least 12 consecutive 
months beginning after the Redemption Date.

          SECTION 10.  CONCERNING THE WARRANT AGENT. (a)  The Warrant Agent 
acts hereunder as agent and in a ministerial capacity for the Company, and 
its duties shall be determined solely by the provisions hereof. The Warrant 
Agent shall not, by issuing and delivering Warrant Certificates or by any 
other act hereunder, be deemed to make any representations as to the validity 
or value or authorization of the Warrant Certificates or the Redeemable 
Warrants represented thereby or of any securities or other property delivered 
upon exercise of any Redeemable Warrant or whether any stock issued upon 
exercise of any Redeemable Warrant is fully paid and nonassessable.

          (b)  The Warrant Agent shall not at any time be under any duty or 
responsibility to any holder of Warrant Certificates to make or cause to be 
made any adjustment of the Exercise Price provided in this Agreement, or to 
determine whether any fact exists which may require any such adjustment, or 
with respect to the nature or extent of any such adjustment, when made, or 
with respect to the method employed in making the same. It shall not (i) be 
liable for any recital or statement of fact contained herein or for any 
action taken, suffered or omitted by it in reliance on any Warrant 
Certificate or other document or instrument believed by it in good faith to 
be genuine and to have been signed or presented by the proper party or 
parties, (ii) be responsible for any failure on the part of the Company to 
comply with any of its covenants and obligations contained in this Agreement 
or in any Warrant Certificate, or (iii) be liable for any act or omission in 
connection with this Agreement except for its own gross negligence, bad faith 
or willful misconduct.

          (c)  The Warrant Agent may at any time consult with counsel 
satisfactory to it (who may be counsel for the Company) and shall incur no 
liability or responsibility for any action taken, suffered or omitted by it 
in good faith in accordance with the opinion or advice of such counsel.

                                      11



          (d)  Any notice, statement, instruction, request, direction, order 
or demand of the Company shall be sufficiently evidenced by an instrument 
signed by the Chairman of the Board of Directors, President, any Vice 
President, or the Treasurer (unless other evidence in respect thereof is 
herein specifically prescribed). The Warrant Agent shall not be liable for 
any action taken, suffered or omitted by it in accordance with such notice, 
statement, instruction, request, direction, order or demand.

          (e)  The Company has agreed in a separate agreement to pay the 
Warrant Agent reasonable compensation or its services hereunder and to 
reimburse it for its reasonable expenses hereunder. The Company further 
agrees to indemnify the Warrant Agent and save it harmless against any and 
all losses, expenses and liabilities, including judgments, costs and counsel 
fees, for anything done or omitted by the Warrant Agent in the execution of 
its duties and powers hereunder except losses, expenses and liabilities 
arising as a result of the Warrant Agent's gross negligence, bad faith or 
willful misconduct.

          (f)  The Warrant Agent may resign its duties and be discharged from 
all further duties and liabilities hereunder (except liabilities arising as a 
result of the Warrant Agent's own gross negligence, bad faith or willful 
misconduct), after giving 30 days' prior written notice to the Company.  At 
least 15 days prior to the date such resignation is to become effective, the 
Warrant Agent shall cause a copy of such notice of resignation to be mailed 
to the Registered Holder of each Warrant Certificate at the Company's 
expense. Upon such resignation the Company shall appoint in writing a 
successor Warrant Agent. If the Company shall fail to make such appointment 
within a period of 30 days after it has been notified in writing of such 
resignation by the resigning Warrant Agent, then the Registered Holder of any 
Warrant Certificate may apply to any court of competent jurisdiction for the 
appointment of a successor Warrant Agent. Any successor Warrant Agent, 
whether appointed by the Company or by such a court, shall be a bond or trust 
company having a capital and surplus, as shown by its last published report 
to its stockholders, of not less than $10,000,000 or a stock transfer company 
doing business in New York, New York. After acceptance in writing of such 
appointment by the successor Warrant Agent is received by the Company, such 
successor Warrant Agent shall be vested with the same powers, rights, duties 
and responsibilities as if it had been originally named herein as the Warrant 
Agent, without any further assurance, conveyance, act or deed; but if for any 
reason it shall be necessary or expedient to execute and deliver any further 
assurance, conveyance, act or deed, the same shall be done at the expense of 
the Company and shall be legally and validly executed and delivered by the 
resigning Warrant Agent. Not later than the effective date of any such 
appointment the Company shall file notice thereof with the resigning Warrant 
Agent and shall forthwith cause a copy of such notice to be mailed to the 
Registered Holder of each Warrant Certificate.

          (g)  Any corporation into which the Warrant Agent may be converted 
or merged, any corporation resulting from any consolidation to which the 
Warrant Agent shall be a party, or any corporation succeeding to the 
corporate trust business of the Warrant Agent shall be the Warrant Agent 
under this Agreement without any further act, provided that such corporation 
is eligible for appointment as successor to the Warrant Agent under the 
provisions of the preceding paragraph. Any such successor Warrant Agent shall 
promptly cause notice of its succession, and a written consent agreeing to 
act hereunder, as Warrant Agent to be mailed to the Company and to the 
Registered Holders of each Warrant Certificate.

                                      12



          (h)  The Warrant Agent, its subsidiaries and affiliates, and any of 
its or their officers or directors, may buy and hold or sell Redeemable 
Warrants or other securities of the Company and otherwise deal with the 
Company in the same manner and to the same extent and with like effect as 
though it were not Warrant Agent. Nothing herein shall preclude the Warrant 
Agent from acting in any other capacity for the Company or any other legal 
entity.

          SECTION 11.  MODIFICATION OF AGREEMENT. The Warrant Agent and the 
Company may by supplemental agreement make any changes or corrections in this 
Agreement (i) that they shall deem appropriate to cure any ambiguity or to 
correct any defective or inconsistent provision or manifest mistake or error 
herein contained; or (ii) that they may deem necessary or desirable and which 
shall not adversely affect the interest of the holders of Warrant 
Certificates; PROVIDED, HOWEVER, that this Agreement shall not otherwise be 
modified, supplemented or altered in any respect except with the consent in 
writing of the Registered Holders representing not less than two-thirds of 
the Redeemable Warrants then outstanding; provided, further, that no change 
in the number or nature of the securities purchasable upon the exercise of 
any Redeemable Warrant, or to increase the Exercise Price therefor, shall be 
made without the consent in writing of the Registered Holders representing 
not less than two-thirds of the Redeemable Warrants then outstanding, other 
than such changes as are presently specifically prescribed by this Agreement 
as originally executed. 

          SECTION 12. NOTICES. All notices, requests, consents and other 
communications hereunder shall be in writing and shall be deemed to have been 
made when delivered or mailed first-class postage prepaid, or delivered to a 
telegraph office for transmission, if to the Registered Holder of a Warrant 
Certificate, at the address of such holder as shown on the registry books 
maintained by the Warrant Agent; if to the Company, at One Kendall Square, 
Building 200, Suite 2200, Cambridge, Massachusetts 02139, Attention: Vice 
President of Finance, Chief Financial Officer and Treasurer, or at such other 
address as may have been furnished to the Warrant Agent in writing by the 
Company; and if to the Warrant Agent, at its Corporate Office. Copies of an 
notice delivered to the Representatives pursuant to this Agreement shall be 
delivered to Neidiger, Tucker, Bruner, Inc., Barclay Plaza, 1675 Larimer 
Street #300, Denver, CO 80202, Attention Anthony B. Petrelli, or at such 
other address as may have been furnished to the Company and the Warrant Agent 
in writing.

          SECTION 13. GOVERNING LAW. This Agreement shall be governed by and 
construed in accordance with the laws of the State of Delaware.

          SECTION 14. BINDING EFFECT. This Agreement shall be binding upon 
and inure to the benefit of the Company, the Warrant Agent and their 
respective successors and assigns and the Registered Holders from time to 
time of Warrant Certificates or any of them. Except as hereinafter stated, 
nothing in this Agreement is intended or shall be construed to confer upon 
any other person any right, remedy or claim or to impose upon any other 
person any duty, liability or obligation.  The Representatives are, and shall 
at all times irrevocably be deemed to be, a third-party beneficiaries of this 
Agreement, with full power, authority and standing to enforce the rights 
granted to it hereunder.

                                       13



          SECTION 15. COUNTERPARTS. This Agreement may be executed in several 
counterparts each with the same effect. Any single counterpart or set of 
counterparts signed, in either case, by all the parties shall constitute a 
full and original document for all purposes.

          IN WITNESS WHEREOF, the parties hereto have caused this Agreement 
to be duly executed as of the date first above written.

[SEAL]

APOLLO BIOPHARMACEUTICS, INC.      AMERICAN STOCK TRANSFER AND
                                   TRUST COMPANY


By:________________________        By:___________________________
   Name:                              Name:
   Title:                             Title:






                                      14



                            EXHIBIT A


No. W_____                                     VOID AFTER MAY_____, 2002

                                               ______________ WARRANTS


                REDEEMABLE WARRANT CERTIFICATE TO
                      PURCHASE COMMON STOCK


                   ____________________________

                                                               CUSIP___


THIS CERTIFIES THAT, FOR VALUE RECEIVED


or registered assigns (the "Registered Holder") is the owner of
the number of Redeemable Warrants (the "Warrants") specified
above. Each Warrant initially entitles the Registered Holder to
purchase, subject to the terms and conditions set forth in this
Certificate and the Warrant Agreement (as hereinafter defined),
one fully paid and nonassessable share of Common Stock, $0.02 par
value, of Apollo BioPharmaceutics, Inc., a Delaware corporation
(the "Company"), at any time from May ____, 1997 (the date of the
Prospectus) (the "Initial Warrant Exercise Date"), and prior to
the Expiration Date (as hereinafter defined), upon the
presentation and surrender of this Warrant Certificate with the
Exercise Form on the reverse hereof duly executed, at the
corporate office of American Stock Transfer and Trust Company, as
Warrant Agent, or its successor (the "Warrant Agent"),
accompanied by payment of $6.50, subject to adjustment (the
"Exercise Price"), in lawful money of the United States of
America in cash or by certified or bank check made payable to the
Company.

          This Warrant Certificate and each Warrant represented
hereby are issued pursuant to and are subject in all respects to
the terms and conditions set forth in the Warrant Agreement (the
"Warrant Agreement"), dated May _____, 1997 (date of the
Prospectus), by and between the Company and the Warrant Agent.

          In the event of certain contingencies provided for in
the Warrant Agreement, the Exercise Price and the number of
shares of Common Stock subject to purchase upon the exercise of
each Warrant represented hereby are subject to modification or
adjustment.

          Each Warrant represented hereby is exercisable at the
option of the Registered Holder, but no fractional interests will
be issued. In the case of the exercise of less than all the
Warrants represented hereby, the Company shall cancel this
Warrant Certificate upon the

                                      1



surrender hereof and shall execute and deliver a new Warrant Certificate 
or Warrant Certificates of like tenor, which the Warrant Agent shall 
countersign, for the balance of such Warrants.

          The term "Expiration Date" shall mean 5:00 p.m. (New
York time) on May _____, 2002 (the date which is the fifth
anniversary of the Initial Warrant Exercise Date). If such date
shall in the City of Boston be a Saturday or Sunday or a day on
which banks are authorized or required to close (a "Business
Day"), then the Expiration Date shall mean 5:00 p.m. (Boston
time) the next following Business Day.

          The Company shall not be obligated to deliver any
securities pursuant to the exercise of this Warrant unless a
registration statement under the Securities Act of 1933, as
amended (the "Securities Act"), with respect to such securities
is effective or unless, in the opinion of counsel to the Company,
an exemption thereunder is available. The Company has covenanted
and agreed that if any securities to be reserved for the purpose
of exercise of the Warrants represented hereby require
registration with, or approval of, any governmental authority
under any federal securities law before such securities may be
validly issued or delivered upon such exercise, then the Company
will file a registration statement under the federal securities
laws or a post-effective amendment, use its reasonable efforts to
cause the same to become or remain effective and to keep such
registration statement current while any of the Warrants are
outstanding, and deliver a prospectus that complies with Section
10(a)(3) of the Securities Act to the Registered Holder
exercising this Warrant. This Warrant shall not be exercisable by
a Registered Holder in any state where such exercise would be
unlawful.

          This Warrant Certificate is exchangeable, upon the
surrender hereof by the Registered Holder at the corporate office
of the Warrant Agent, for a new Warrant Certificate or Warrant
Certificates of like tenor representing an equal aggregate number
of Warrants, each of such new Warrant Certificates to represent
such number of Warrants as shall be designated by such Registered
Holder at the time of such surrender. Upon the presentment and
payment of any tax or other charge imposed in connection
therewith or incident thereto, for registration of transfer of
this Warrant Certificate at such office, a new Warrant
Certificate or Warrant Certificates representing an equal
aggregate number of Warrants will be issued to the transferee in
exchange therefor, subject to the limitations provided in the
Warrant Agreement.

          Prior to the exercise of any Warrant represented
hereby, the Registered Holder, as such, shall not be entitled to
any rights of a stockholder of the Company, including, without
limitation, the right to vote or to receive dividends or other
distributions, and shall not be entitled to receive any notice of
any proceedings of the Company, except as provided in the Warrant
Agreement.

          Subject to the provisions of the Warrant Agreement,
this Warrant may be redeemed at the option of the Company, at a
redemption price of $0.25 per Warrant, at any time commencing
after the Initial Warrant Exercise Date, PROVIDED that (i) the
average closing bid price for the Company's Common Stock in the
over-the-counter market as reported by the National Association
of Securities Dealers Automated Quotation System, or (ii) the
closing sale price on the primary exchange on which the Common
Stock is traded, if the Common Stock is traded on a national
securities exchange, shall have for 20 consecutive days on which
such market is open for trading ending within ten days prior to
the Notice of Redemption, as defined below, 

                                       2



equaled or exceeded $10.00 per share (subject to adjustment in the event of 
any stock splits or other similar events). Notice of redemption (the "Notice 
of Redemption") shall be given by the Company not later than the thirtieth 
day before the date fixed for redemption, all as provided in the Warrant 
Agreement. On and after the date fixed for redemption, the Registered Holder 
shall have no right with respect to this Warrant except to receive the $0.25 
per Warrant upon surrender of this Certificate.

          Under certain circumstances described in the Warrant Agreement, 
Neidiger/ Tucker/ Bruner, Inc. shall be entitled to receive as a solicitation 
fee an aggregate of five percent (5%) of the Exercise Price of the Warrants 
represented hereby.

          Prior to due presentment for registration of transfer hereof, the 
Company and the Warrant Agent may deem and treat the Registered Holder as the 
absolute owner hereof and of each Warrant represented hereby (notwithstanding 
any notations of ownership or writing hereon made by anyone other than a duly 
authorized officer of the Company or the Warrant Agent) for all purposes and 
shall not be affected by any notice to the contrary, except as provided in 
the Warrant Agreement.

          This Warrant Certificate shall be governed by and construed in 
accordance with the laws of the State of Delaware.

          This Warrant Certificate is not valid unless countersigned by the 
Warrant Agent.

          IN WITNESS WHEREOF, the Company has caused this Warrant Certificate 
to be duly executed, manually or in facsimile by two of its officers 
thereunto duly authorized and a facsimile of its corporate seal to be 
imprinted hereon.

          Dated May _____, 1997


SEAL                               APOLLO BIOPHARMACEUTICS, INC.



                                   By:___________________________________
                                       Name:
                                       Title:

                                   By:___________________________________
                                       Name:
                                       Title:
 


                                      3



COUNTERSIGNED:

AMERICAN STOCK TRANSFER
AND TRUST COMPANY
as Warrant Agent



By: ___________________________
     Authorized Officer 



                                      4



                          EXERCISE FORM


             To Be Executed by the Registered Holder
                   in Order to Exercise Warrant


          The undersigned Registered Holder hereby irrevocably
elects to exercise __________ Warrants represented by this
Warrant Certificate, and to purchase the securities issuable upon
the exercise of such Warrants, and requests that certificates for
such securities shall be issued in name of

                  PLEASE INSERT SOCIAL SECURITY
                   OR OTHER IDENTIFYING NUMBER


                 _______________________________ 

                 _______________________________ 
                                        
                 _______________________________

                 _______________________________
                (please print or type name and address)


and be delivered to


                                        
                 _______________________________

                 _______________________________
                                        
                 _______________________________

                 _______________________________
                 (please print or type name and address)


and if such number of Warrants shall not be all the Warrants
evidenced by this Warrant Certificate, that a new Warrant
Certificate for the balance of such Warrants be registered in the
name of, and delivered to, the Registered Holder at the address
stated below.
 
                                     5


            IMPORTANT: PLEASE COMPLETE THE FOLLOWING:

          1.   The exercise of this Warrant was
               solicited by Neidiger/ Tucker/
               Bruner, Inc. unless the following
               box is checked.                     
                                 

                                                       

          2.   The exercise of this Warrant was
               solicited by

               ____________________________________
                                                  


          3.   If the exercise of this Warrant was
               not solicited, please check the
               following box.                      
                                 




Dated: _____________________________  X __________________________
   
                                        __________________________

                                                                  
                                        __________________________
                                        Address


                                        __________________________
                                        Social Security or Taxpayer
                                        Identification Number


                                        ___________________________
                                        Signature Guaranteed

                                      6


 
                            ASSIGNMENT

             To Be Executed by the Registered Holder
                   in Order to Assign Warrants


FOR VALUE RECEIVED,___________________, hereby sells, assigns and
transfers unto


                  PLEASE INSERT SOCIAL SECURITY
                   OR OTHER IDENTIFYING NUMBER

                 _______________________________
                                        
                 _______________________________

                 _______________________________
                                        
                 _______________________________
                 (please print or type name and address)


____________ of the Warrants represented by this Warrant
Certificate, and hereby irrevocably constitutes and appoints
_____________________________ as its/his/her attorney-in-fact to
transfer this Warrant Certificate on the books of the Company,
with full power of substitution in the premises.


Dated: _____________________________ X __________________________ 
                                          Signature Guaranteed


THE SIGNATURE TO THE ASSIGNMENT OR THE EXERCISE FORM MUST
CORRESPOND TO THE NAME AS WRITTEN UPON THE FACE OF THIS WARRANT
CERTIFICATE IN EVERY PARTICULAR, WITHOUT ALTERATION ON OR
ENLARGEMENT OR ANY CHANGE WHATSOEVER AND MUST BE GUARANTEED BY A
BANK, BROKER, DEALER, CREDIT UNION, SAVINGS ASSOCIATION OR OTHER
ENTITY WHICH IS A MEMBER IN GOOD STANDING OF THE SECURITIES
TRANSFER AGENTS MEDALLION PROGRAM.


                                      7