EXHIBIT 11.1---STATEMENT RE: COMPUTATION OF PER SHARE EARNINGS (UNAUDITED) GALAGEN INC. (A DEVELOPMENT STAGE COMPANY) Period from November 17, For the Three Months Ended 1987 (inception) to -------------------------- March 31, March 31, 1997 March 31, 1996 1997 -------------- -------------- ------------------- Primary Loss Per Share: Average shares outstanding 7,163,769 1,955,569 2,199,853 SAB No. 83 shares - for stock options granted at exercise prices less than the initial public offering price during the 12 months preceding the initial public offering using the treasury method - - 115,063 --------------------------------------------------------- Total 7,163,769 1,955,569 2,314,916 --------------------------------------------------------- --------------------------------------------------------- Net loss $(1,576,928) $(1,471,233) $(48,760,848) --------------------------------------------------------- --------------------------------------------------------- Net loss per share $(0.22) $(0.75) $(21.06) --------------------------------------------------------- --------------------------------------------------------- Fully Diluted Loss Per Share: Average shares outstanding 7,163,769 1,955,569 2,199,853 SAB No. 83 shares - for stock options granted at exercise prices less than the initial public offering price during the 12 months preceding the initial public offering using the treasury method - - 115,063 Assumed conversion of all series of convertible preferred stock - 3,126,159 644,431 --------------------------------------------------------- Total 7,163,769 5,081,728 2,959,347 --------------------------------------------------------- --------------------------------------------------------- Net loss $(1,576,928) $(1,471,233) $(48,760,848) --------------------------------------------------------- --------------------------------------------------------- Net loss per share $(0.22) $(0.29) $(16.48) --------------------------------------------------------- ---------------------------------------------------------