Exhibit 10.3

1.  Adopted by the Board of Directors on May 1, 1993; Approved by the
    stockholders on June 25, 1993.
2.  Amended by the Board of Directors on September 24, 1993 (No stockholder
    approval required).
3.  Amended by the Board of Directors on October 24, 1994, March 17, 1995 and
    April 6, 1995; Approved by the stockholders on May 19, 1995.
4.  Amended by the Board of Directors on March 13, 1996; Approved by the
    stockholders on May 15, 1996.
5.  Amended by the Board of Directors on March 3, 1997; Approved by the
    stockholders on May 28, 1997.

                           GENZYME TRANSGENICS CORPORATION

                              1993 Equity Incentive Plan

Section 1.  Purpose

    The purpose of the Genzyme Transgenics Corporation 1993 Equity Incentive 
Plan (the "Plan") is to attract and retain key employees and consultants to 
provide an incentive for them to assist the Company to achieve long-range 
performance goals, and to enable them to participate in the long-term growth 
of the Company.

Section 2.  Definitions

    "Affiliate" means any business entity in which the Company owns directly 
or indirectly 50% or more of the total combined voting power or has a 
significant financial interest as determined by the Committee.

    "Award" means any Option, Stock Appreciation Right, Performance Share, 
Restricted Stock or Stock Unit awarded under the Plan.

    "Board" means the Board of Directors of the Company.

    "Code" means the Internal Revenue Code of 1986, as amended from time to 
time.

    "Committee" means either any one of one or more committees of the Board 
appointed by the Board to administer the Plan, the members of which are 
"Non-Employee Directors" within the meaning of Rule 16b-3 under the 
Securities Exchange Act of 1934, as amended, or any successor provision (the 
"Rule") to the extent necessary to comply with the Rule.

    "Common Stock" or "Stock" means the Common Stock, $0.01 par value, of the
Company.

    "Company" means Genzyme Transgenics Corporation.

    "Designated Beneficiary" means the beneficiary designated by a Participant,
in a manner determined by the Committee, to receive amounts due or exercise
rights of the 



Participant in the event of the Participant's death.  In the absence of an 
effective designation by a Participant, designated Beneficiary shall mean the 
Participant's estate.

    "Fair Market Value" means, with respect to Common Stock or any other 
property, the fair market value of such property as determined by the 
Committee in good faith or in the manner established by the Committee from 
time to time.

    "Incentive Stock Option" means an option to purchase shares of Common 
Stock awarded to a Participant under Section 6 which is intended to meet the 
requirements of Section 422 of the Code or any successor provision.

    "Nonstatutory Stock Option" means an option to purchase shares of Common 
Stock awarded to a Participant under Section 6 which is not intended to be an 
Incentive Stock Option.

    "Option" means an Incentive Stock Option or a Nonstatutory Stock Option.

    "Participant" means a person selected by the Committee to receive an 
Award under the Plan.

    "Performance Cycle" or "Cycle" means the period of time selected by the 
Committee during which performance is measured for the purpose of determining 
the extent to which an award of Performance Shares has been earned.

    "Performance Shares" mean shares of Common Stock which may be earned by 
the achievement of performance goals awarded to a Participant under Section 8.

    "Reporting Person" means a person subject to Section 16 of the Securities 
Exchange Act of 1934 or any successor provision.

    "Restricted Period" means the period of time selected by the Committee 
during which an award of Restricted Stock may be forfeited to the Company.

    "Restricted Stock" means shares of Common Stock subject to forfeiture 
awarded to a Participant under Section 9.

    "Stock Appreciation Right" or "SAR" means a right to receive any excess 
in value of shares of Common Stock over the exercise price awarded to a 
Participant under Section 7.

    "Stock Unit" means an award of Common Stock or units that are valued in 
whole or in part by reference to, or otherwise based on, the value of Common 
Stock, awarded to a Participant under Section 10.

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Section 3.  Administration

    The Plan shall be administered by the Committee.  The Committee shall 
have authority to adopt, alter and repeal such administrative rules, 
guidelines and practices governing the operation of the Plan as it shall from 
time to time consider advisable, and to interpret the provisions of the Plan. 
 The Committee's decisions shall be final and binding.  To the extent 
permitted by applicable law, the Committee may delegate to one or more 
executive officers of the Company the power to make Awards to Participants 
who are not Reporting Persons and all determinations under the Plan with 
respect thereto, provided that the Committee shall fix the maximum amount of 
such Awards for the group and a maximum for any one Participant.

Section 4.  Eligibility

    All employees, and in the case of Awards other than Incentive Stock 
Options, consultants of the Company or any Affiliate capable of contributing 
significantly to the successful performance of the Company, other than a 
person who has irrevocably elected not to be eligible, are eligible to be 
Participants in the Plan.

Section 5.  Stock Available for Awards

    (a)  Subject to adjustment under subsection (b), Awards may be made under 
the Plan for up to 2,515,000(1) shares of Common Stock.  If any Award in respect
of shares of Common Stock expires or is terminated unexercised or is 
forfeited for any reason or settled in a manner that results in fewer shares 
outstanding than were initially awarded, including without limitation the 
surrender of shares in payment for the Award or any tax obligation thereon, 
the shares subject to such Award or so surrendered, as the case may be, to 
the extent of such expiration, termination, forfeiture or decrease, shall 
again be available for award under the Plan, subject, however, in the case of 
Incentive Stock Options, to any limitation required under the Code.  Common 
Stock issued through the assumption or substitution of outstanding grants 
from an acquired company shall not reduce the shares available for Awards 
under the Plan.  Shares issued under the Plan may consist in whole or in part 
of authorized but unissued shares or treasury shares.

     (b)  In the event that the Committee determines that any stock dividend, 
extraordinary cash dividend, creation of a class of equity securities, 
recapitalization, reorganization, merger, consolidation, split-up, spin-off, 
combination, exchange of shares, warrants or rights offering to purchase 
Common Stock at a price substantially below fair 


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(1) This number includes 224,350 shares reserved for issuance upon the exercise 
of outstanding options to purchase shares of common stock of TSI Corporation, 
which options were assumed by the Company in October 1994 in connection with 
the Company's acquisition of TSI Corporation.

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market value, or other similar transaction affects the Common Stock such that 
an adjustment is required in order to preserve the benefits or potential 
benefits intended to be made available under the Plan, then the Committee, 
subject, in the case of Incentive Stock Options, to any limitation required 
under the Code, shall equitably adjust any or all of (i) the number and kind 
of shares in respect of which Awards may be made under the Plan, (ii) the 
number and kind of shares subject to outstanding Awards, and (iii) the award, 
exercise or conversion price with respect to any of the foregoing, and if 
considered appropriate, the Committee may make provision for a cash payment 
with respect to an outstanding Award, provided that the number of shares 
subject to any Award shall always be a whole number.

Section 6.  Stock Options

     (a)  Subject to the provisions of the Plan, the Committee may award 
Incentive Stock Options and Nonstatutory Stock Options and determine the 
number of shares to be covered by each Option, the option price therefor and 
the conditions and limitations applicable to the exercise of the Option.  The 
terms and conditions of Incentive Stock Options shall be subject to and 
comply with Section 422 of the Code, or any successor provision, and any 
regulations thereunder.

     (b)  The Committee shall establish the option price at the time each 
Option is awarded, which price shall not be less than 100% of the Fair Market 
Value of the Common Stock on the date of award.

     (c)  Each Option shall be exercisable at such times and subject to such 
terms and conditions as the Committee may specify in the applicable Award or 
thereafter.  The Committee may impose such conditions with respect to the 
exercise of Options, including conditions relating to applicable federal or 
state securities laws, as it considers necessary or advisable.

     (d)  No shares shall be delivered pursuant to any exercise of an Option 
until payment in full of the option price therefor is received by the 
Company. Such payment may be made in whole or in part in cash or, to the 
extent permitted by the Committee at or after the award of the Option, by 
delivery of a note or shares of Common Stock owned by the optionee, including 
Restricted Stock, valued at their Fair Market Value on the date of delivery, 
or such other lawful consideration as the Committee may determine.

     (e)  The Committee may provide for the automatic award of an Option upon 
the delivery of shares to the Company in payment of an Option for up to the 
number of shares so delivered.

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Section 7.  Stock Appreciation Rights

     (a)  Subject to the provisions of the Plan, the Committee may award SARs 
in tandem with an Option (at or after the award of the Option), or alone and 
unrelated to an Option.  SARs in tandem with an Option shall terminate to the 
extent that the related Option is exercised, and the related Option shall 
terminate to the extent that the tandem SARs are exercised.  SARs shall have 
an exercise price of not less than the Fair Market Value of the Common Stock 
on the date of award, or in the case of SARs in tandem with Options, the 
exercise price of the related Option.

     (b)  An SAR related to an Option which can only be exercised during 
limited periods following a change in control of the Company, may entitle the 
Participant to receive an amount based upon the highest price paid or offered 
for Common Stock in any transaction relating to the change in control or paid 
during the thirty-day period immediately preceding the occurrence of the 
change in control in any transaction reported in the stock market in which 
the Common Stock is normally traded.

Section 8.  Performance Shares

     (a)  Subject to the provisions of the Plan, the Committee may award 
Performance Shares and determine the number of such shares for each 
Performance Cycle and the duration of each Performance Cycle.  There may be 
more than one Performance Cycle in existence at any one time, and the 
duration of Performance Cycles may differ from each other.  The payment value 
of Performance Shares shall be equal to the Fair Market Value of the Common 
Stock on the date the Performance Shares are earned or, in the discretion of 
the Committee, on the date the Committee determines that the Performance 
Shares have been earned.

     (b)  The Committee shall establish performance goals for each Cycle, for 
the purpose of determining the extent to which Performance Shares awarded for 
such Cycle are earned, on the basis of such criteria and to accomplish such 
objectives as the Committee may from time to time select.  During any Cycle, 
the Committee may adjust the performance goals for such Cycle as it deems 
equitable in recognition of unusual or non-recurring events affecting the 
Company, changes in applicable tax laws or accounting principles, or such 
other factors as the Committee may determine.

     (c)  As soon as practicable after the end of a Performance Cycle, the 
Committee shall determine the number of Performance Shares which have been 
earned on the basis of performance in relation to the established performance 
goals.  The payment values of earned Performance Shares shall be distributed 
to the Participant or, if the Participant has died, to the Participant's 
Designated Beneficiary, as soon as practicable thereafter.  The Committee 
shall determine, at or after the time of award, whether payment values will 
be settled in whole or in part in cash or other property, including Common 
Stock or Awards.

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Section 9.  Restricted Stock

     (a)  Subject to the provisions of the Plan, the Committee may award 
shares of Restricted Stock and determine the duration of the Restricted 
Period during which, and the conditions under which, the shares may be 
forfeited to the Company and the other terms and conditions of such Awards.  
Shares of Restricted Stock shall be issued for no cash consideration or such 
minimum consideration as may be required by applicable law.

     (b)  Shares of Restricted Stock may not be sold, assigned, transferred, 
pledged or otherwise encumbered, except as permitted by the Committee, during 
the Restricted Period.  Shares of Restricted Stock shall be evidenced in such 
manner as the Committee may determine.  Any certificates issued in respect of 
shares of Restricted Stock shall be registered in the name of the Participant 
and unless otherwise determined by the Committee, deposited by the 
Participant, together with a stock power endorsed in blank, with the Company. 
 At the expiration of the Restricted Period, the Company shall deliver such 
certificates to the Participant or if the Participant has died, to the 
Participant's Designated Beneficiary.

Section 10.  Stock Units

     (a)  Subject to the provisions of the Plan, the Committee may award 
Stock Units subject to such terms, restrictions, conditions, performance 
criteria, vesting requirements and payment rules as the Committee shall 
determine.

     (b)  Shares of Common Stock awarded in connection with a Stock Unit 
Award shall be issued for no cash consideration or such minimum consideration 
as may be required by applicable law.

Section 11.  General Provisions Applicable to Awards

     (a)  Limitations on Transferability.  Options shall not be transferable 
by the recipient other than by will or the laws of descent and distribution 
and are exercisable during such person's lifetime only by such person or by 
such person's guardian or legal representative; provided that the Committee 
may in its discretion waive such restriction in any case.

     (b)  Documentation.  Each Award under the Plan shall be evidenced by a 
writing delivered to the Participant specifying the terms and conditions 
thereof and containing such other terms and conditions not inconsistent with 
the provisions of the Plan as the Committee considers necessary or advisable 
to achieve the purposes of the Plan or comply with applicable tax and 
regulatory laws and accounting principles.

     (c)  Committee Discretion.  Each type of Award may be made alone, in 
addition to or in relation to any other type of Award.  The terms of each 
type of Award need not be identical, and the Committee need not treat 
Participants uniformly.  Except as otherwise 

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provided by the Plan or a particular Award, any determination with respect to 
an Award may be made by the Committee at the time of award or at any time 
thereafter.

     (d)  Settlement.  The Committee shall determine whether Awards are 
settled in whole or in part in cash, Common Stock, other securities of the 
Company, Awards or other property.  The Committee may permit a Participant to 
defer all or any portion of a payment under the Plan, including the crediting 
of interest on deferred amounts denominated in cash and dividend equivalents 
on amounts denominated in Common Stock.

     (e)  Dividends and Cash Awards  In the discretion of the Committee, any 
Award under the Plan may provide the Participant with (i) dividends or 
dividend equivalents payable currently or deferred with or without interest, 
and (ii) cash payments in lieu of or in addition to an Award.

     (f)  Termination of Employment.  The Committee shall determine the 
effect on an Award of the disability, death, retirement or other termination 
of employment of a Participant and the extent to which, and the period during 
which, the Participant's legal representative, guardian or Designated 
Beneficiary may receive payment of an Award or exercise rights thereunder.

     (g)  Change in Control.  In order to preserve a Participant's rights 
under an Award in the event of a change in control of the Company, the 
Committee in its discretion may, at the time an Award is made or at any time 
thereafter, take one or more of the following actions:  (i) provide for the 
acceleration of any time period relating to the exercise or realization of 
the Award, (ii) provide for the purchase of the Award upon the Participant's 
request for an amount of cash or other property that could have been received 
upon the exercise or realization of the Award had the Award been currently 
exercisable or payable, (iii) adjust the terms of the Award in a manner 
determined by the Committee to reflect the change in control, (iv) cause the 
Award to be assumed, or new rights substituted therefor, by another entity, 
or (v) make such other provision as the Committee may consider equitable and 
in the best interests of the Company.

     (h)  Withholding.  The Participant shall pay to the Company, or make 
provision satisfactory to the Committee for payment of, any taxes required by 
law to be withheld in respect of Options under the Plan no later than the 
date of the event creating the tax liability.  The Company and its Affiliates 
may, to the extent permitted by law, deduct any such tax obligations from any 
payment of any kind otherwise due to the Participant.  In the Committee's 
discretion, the Participant may pay any taxes due with respect to an Option 
in whole or in part in shares of Common Stock, including shares retained from 
the Option creating the tax obligation, valued at their Fair Market Value on 
the date of retention or delivery.

     (i)  Foreign Nationals.  Awards may be made to Participants who are 
foreign nationals or employed outside the United States on such terms and 
conditions different from those specified in the Plan as the Committee 
considers necessary or advisable to achieve the purposes of the Plan or 
comply with applicable laws.

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     (j)  Amendment of Award.  The Committee may amend, modify or terminate 
any outstanding Award, including substituting therefor another Award of the 
same or a different type, changing the date of exercise or realization and 
converting an Incentive Stock Option to a Nonstatutory Stock Option, provided 
that the Participant's consent to such action shall be required unless the 
Committee determines that the action, taking into account any related action, 
would not materially and adversely affect the Participant.

Section 12.  Miscellaneous

     (a)  Limitation on Number of Shares Granted.  Notwithstanding any other 
provision of the Plan, the aggregate number of shares of Common Stock subject 
to Options and SARs that may be granted within any fiscal year to any one 
Eligible Person under the Plan shall not exceed that number of shares equal 
to 20% of the total number of shares reserved for issuance under the Plan, 
except for grants to new hires during the fiscal year of hiring which shall 
not exceed that number of shares equal to 30% of the total number of shares 
reserved for issuance under the Plan.

     (b)  No Right To Employment.  No person shall have any claim or right to 
be granted an Award, and the grant of an Award shall not be construed as 
giving a Participant the right to continued employment.  The Company 
expressly reserves the right at any time to dismiss a Participant free from 
any liability or claim under the Plan, except as expressly provided in the 
applicable Award.

     (c)  No Rights As Shareholder.  Subject to the provisions of the 
applicable Award, no Participant or Designated Beneficiary shall have any 
rights as a shareholder with respect to any shares of Common Stock to be 
distributed under the Plan until he or she becomes the holder thereof.  A 
Participant to whom Common Stock is awarded shall be considered the holder of 
the Stock at the time of the Award except as otherwise provided in the 
applicable Award.

     (d)  Effective Date.  Subject to the approval of the shareholders of the 
Company, the Plan shall be effective on May 1, 1993.  Prior to such approval, 
Awards may be made under the Plan expressly subject to such approval.

     (e)  Amendment of Plan.  The Board may amend, suspend or terminate the 
Plan or any portion thereof at any time, provided that no amendment shall be 
made without shareholder approval if such approval is necessary to comply 
with any applicable tax or regulatory requirement.

     (f)  Governing Law.  The provisions of the Plan shall be governed by and 
interpreted in accordance with the laws of the Commonwealth of Massachusetts.


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