EXHIBIT 99.1

                                 FIRST AMENDMENT
                                     TO THE
                       SECOND AMENDED AND RESTATED BY-LAWS
                                       OF
                               NOVOSTE CORPORATION
                             DATED OCTOBER 16, 2002

     Article III Section  3.03 of the Second  Amended  and  Restated  By-Laws of
Novoste  Corporation  (the  "By-laws")  shall be  amended  and  restated  in its
entirety to read as follows:

     "Section 3.03. Special Meetings.

          a. A special meeting of the  shareholders for any purpose or purposes,
     unless  otherwise  prescribed by statute,  may be called at any time by the
     President,  the  Chairman,  by order  of the  Board  of  Directors  or by a
     shareholder or shareholders holding of record at least ten percent (10%) in
     voting power of the outstanding shares of the Corporation  entitled to vote
     at such meeting. Business transacted at any special meeting of shareholders
     shall be limited to the purposes stated in the notice of meeting thereof.

          b. Any  shareholder(s)  wishing to call a special meeting  pursuant to
     subparagraph  (a) of this  Section  3.03 shall  provide  notice  thereof in
     writing to the  Secretary of the  Corporation  at the  principal  executive
     offices of the Corporation.  Such shareholder's notice shall set forth: (1)
     a brief description of the business that the shareholder  proposes to bring
     before the special meeting, the text of the proposal or business (including
     the text of any  resolutions  proposed for  consideration  and in the event
     that  such  business  includes  a  proposal  to amend  the  By-Laws  of the
     Corporation,  the  language  of the  proposed  amendment),  the reasons for
     conducting such business at the special  meeting and any material  interest
     in such business of such  shareholder and the beneficial  owner, if any, on
     whose behalf the proposal is made;  (2) if the matters to be  considered at
     the special  meeting  include the election of directors,  such  shareholder
     notice shall set forth as to each person whom the  shareholder  proposes to
     nominate for election as a director  (A) all  information  relating to such
     person that is required to be  disclosed  in  solicitations  of proxies for
     election of directors in an election contest, or is otherwise required,  in
     each case  pursuant  to and in  accordance  with  Regulation  14A under the
     Securities  Exchange Act of 1934, as amended (the  "Exchange  Act") and (B)
     such person's  written  consent to being named in the proxy  statement as a
     nominee and to serving as a director if elected;  (3) as to the shareholder
     giving the notice and the  beneficial  owner,  if any, on whose  behalf the
     nomination   or  proposal  is  made  (A)  the  name  and  address  of  such
     shareholder,  as  they  appear  on the  Corporation's  books,  and of  such



     beneficial  owner,  (B) the class and number of shares of capital  stock of
     the  Corporation  which  are  owned  beneficially  and of  record  by  such
     shareholder and such beneficial  owner, and (C) a  representation  that the
     shareholder is a holder of record of stock of the  Corporation  entitled to
     vote at such special meeting and intends to appear in person or by proxy at
     the  special  meeting to propose  such  business or  nomination;  and (4) a
     request  that the Board of  Directors  fix a record date and a meeting date
     for such special meeting.

          Upon receipt of such notice,  the Secretary of the  Corporation  shall
     make a  determination  as to whether such notice is in accordance  with the
     informational  requirements  of  this  subsection  (b).  If  the  Secretary
     determines  that the  notice is not in  accordance  with the  informational
     requirements  of this  subsection  (b),  the  Secretary  shall  notify  the
     shareholder(s) in writing of such  determination and the reasons therefore.
     If the  Secretary  determines  that the  notice is in  accordance  with the
     informational  requirements  of this  subsection  (b), the Secretary  shall
     notify the Board of  Directors  of such  determination.  Upon notice by the
     Secretary that such notice has been received and is in accordance  with the
     informational  requirements  of this subsection (b), the Board of Directors
     shall meet (or take action by written  consent) within 10 days therefrom to
     fix (x) a record  date in order  that the  Corporation  may  determine  the
     shareholders  entitled to notice of and to vote at the special  meeting and
     (y) a meeting date and location for such special meeting.  Such record date
     shall not  precede  the date upon which such  Board of  Directors'  meeting
     occurs or written  consent is  executed  and shall not be more than 10 days
     after  the date upon  which  such  Board of  Directors'  meeting  occurs or
     written consent is executed.  Such meeting date shall be no earlier than 45
     days and no later than 70 days after the record date."

     Article III of the  By-Laws  shall be amended to add  Section  3.07,  which
shall read in its entirety as follows:

     "Section 3.07. Notice of Shareholder Business and Nominations.

          a. Annual  Meetings of  Shareholders.  (1)  Nominations of persons for
     election to the Board of Directors of the  Corporation  and the proposal of
     business  to be  considered  by the  shareholders  may be made at an annual
     meeting of shareholders  only (A) pursuant to the  Corporation's  notice of
     meeting (or any  supplement  thereto),  (B) by or at the  direction  of the
     Board of Directors or (C) by any  shareholder of the  Corporation who was a
     shareholder of record of the  Corporation  at the time the notice  provided
     for in this Section 3.07 is delivered to the Secretary of the  Corporation,
     who is entitled to vote at the  meeting  and who  complies  with the notice
     procedures set forth in this Section 3.07.

          (2) For nominations or other business to be properly brought before an
     annual meeting by a shareholder  pursuant to clause (C) of paragraph (a)(1)
     of this Section 3.07, the shareholder must have given timely notice thereof
     in  writing  to the  Secretary  of the  Corporation  and any such  proposed
     business other than the nominations of persons for election to the Board of


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     Directors must  constitute a proper matter for  shareholder  action.  To be
     timely,  a shareholder's  notice shall be delivered to the Secretary at the
     principal  executive offices of the Corporation not later than the close of
     business on the ninetieth day nor earlier than the close of business on the
     one hundred  twentieth day prior to the first  anniversary of the preceding
     year's annual meeting (provided,  however, that in the event that no annual
     meeting  was held in the prior  year or the date of the  annual  meeting is
     more than thirty days before or more than sixty days after such anniversary
     date,  notice by the  shareholder  must be so delivered  not later than the
     tenth day following the earlier of (A) the day on which public announcement
     of the date of such  meeting  is first made by the  Corporation  or (B) the
     date notice of the meeting was mailed to  shareholders).  In no event shall
     the public  announcement  of an  adjournment or  postponement  of an annual
     meeting  commence a new time  period (or  extend any time  period)  for the
     giving of a shareholder's  notice as described  above.  Such  shareholder's
     notice shall set forth: (A) as to each person whom the shareholder proposes
     to nominate for election as a director (i) all information relating to such
     person that is required to be  disclosed  in  solicitations  of proxies for
     election of directors in an election contest, or is otherwise required,  in
     each case  pursuant  to and in  accordance  with  Regulation  14A under the
     Exchange Act and (ii) such person's  written  consent to being named in the
     proxy  statement as a nominee and to serving as a director if elected;  (B)
     as to any other business that the shareholder  proposes to bring before the
     meeting,  a brief  description of the business desired to be brought before
     the meeting,  the text of the proposal or business  (including  the text of
     any  resolutions  proposed  for  consideration  and in the event  that such
     business  includes a proposal to amend the By-Laws of the Corporation,  the
     language  of the  proposed  amendment),  the reasons  for  conducting  such
     business at the  meeting,  any material  interest in such  business of such
     shareholder and the beneficial  owner, if any, on whose behalf the proposal
     is made and all  information  relating to such business that is required to
     be disclosed in solicitations of proxies for such business, or is otherwise
     required,  in each case pursuant to and in accordance  with  Regulation 14A
     under the Exchange Act; and (C) as to the shareholder giving the notice and
     the beneficial owner, if any, on whose behalf the nomination or proposal is
     made (i) the name and  address of such  shareholder,  as they appear on the
     Corporation's  books,  and of such  beneficial  owner,  (ii) the  class and
     number  of  shares  of  capital  stock of the  Corporation  which are owned
     beneficially and of record by such  shareholder and such beneficial  owner,
     (iii) a representation  that the shareholder is a holder of record of stock
     of the  Corporation  entitled to vote at such meeting and intends to appear
     in  person  or by  proxy  at  the  meeting  to  propose  such  business  or
     nomination,  and  (iv) a  representation  whether  the  shareholder  or the
     beneficial  owner, if any,  intends or is part of a group which intends (x)
     to deliver a proxy  statement  and/or  form of proxy to holders of at least
     the percentage of the Corporation's  outstanding  capital stock required to
     approve or adopt the proposal or elect the nominee  and/or (y) otherwise to
     solicit   proxies  from   shareholders  in  support  of  such  proposal  or
     nomination.  The foregoing notice requirements shall be deemed satisfied by
     a shareholder if the shareholder has notified the Corporation of his or her
     intention  to present a proposal at an annual  meeting in  compliance  with


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     Rule 14a-8 (or any successor  thereof)  promulgated  under the Exchange Act
     and such shareholder's proposal has been included in a proxy statement that
     has been  prepared by the  Corporation  to solicit  proxies for such annual
     meeting.  The Corporation may require any proposed  nominee to furnish such
     other information as it may reasonably require to determine the eligibility
     of such proposed nominee to serve as a director of the Corporation.

          b. Notwithstanding anything in the second sentence of paragraph (a)(2)
     of this  Section  3.07 to the  contrary,  in the event  that the  number of
     directors to be elected to the Board of Directors of the  Corporation at an
     annual meeting is increased and a public  announcement  by the  Corporation
     naming the nominees for the additional  directorships  is not made at least
     one hundred days prior to the first  anniversary  of the  preceding  year's
     annual meeting,  then a shareholder's  notice required by this Section 3.07
     shall also be considered  timely, but only with respect to nominees for the
     additional  directorships,  if it shall be  delivered  to the  Secretary in
     writing at the principal  executive  offices of the  Corporation  not later
     than the close of business on the tenth day following the day on which such
     public announcement is first made by the Corporation."


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