EXHIBIT 99.1


                                                                  [COMPANY LOGO]
FOR IMMEDIATE RELEASE

                MICROTEK MEDICAL HOLDINGS REPORTS FOURTH QUARTER
                              AND FULL YEAR RESULTS

                   NET PRODUCT SALES FOR FY 2003 INCREASED BY
                     15.8% OVER PRIOR YEAR TO $98.7 MILLION

               RELEASES REVENUE AND EARNINGS FORECASTS FOR FY 2004

COLUMBUS,  MS,  February 24, 2004 - Microtek  Medical  Holdings,  Inc.  (Nasdaq:
MTMD), a leading manufacturer and marketer of infection control products,  fluid
control  products  and  safety  products  to  healthcare  professionals,   today
announced its results for the fourth  quarter and twelve  months ended  December
31, 2003.

Highlights from the fourth quarter and full year of 2003 are as follows:

     o    Fourth  quarter 2003 net product sales  increased by 21.5 percent over
          the same 2002 quarter to $26.5 million.
     o    Full year 2003 net product  sales  increased by 15.8 percent over 2002
          to $98.7 million.
     o    Gross  margin  and  operating   margin   demonstrated   year-over-year
          improvements.
     o    Fourth  quarter  2003 net income was $5.7 million or $0.13 per diluted
          share,  including  non-cash  benefits  of $3.9  million  or $0.09  per
          diluted  share from the decrease in the  Company's  allowance  for its
          deferred tax assets.
     o    Full year 2003,  net income was $16.0  million,  or $0.37 per  diluted
          share,  including  non-cash  benefits  of $8.8  million,  or $0.20 per
          diluted share from the decrease in the Company's  valuation  allowance
          for its deferred tax assets.

     o    The Company  broadened its proprietary  product offerings and expanded
          its distribution  capabilities through the acquisition of Plasco, Inc.
          completed effective November 1, 2003.

FOURTH QUARTER AND FULL YEAR RESULTS

For the quarter ended December 31, 2003, net revenues  increased 19.5 percent to
$26.5  million  versus  $22.1  million in the same  quarter  last year and $24.3
million in the third quarter of 2003.  Net product sales (which are net revenues
excluding  licensing  revenues) in the fourth  quarter of 2003 increased by $4.7
million,  or 21.5 percent,  over the fourth quarter of 2002.  Included in fourth
quarter 2003 net product sales is  approximately  $1.1 million from the recently
acquired Plasco division.

Net income and  earnings per diluted  share for the fourth  quarter of 2003 were
$5.7  million  or  $0.13,  respectively,  compared  to $4.8  million  or  $0.11,
respectively,  for the fourth  quarter of 2002.  Included in the fourth  quarter
2003  earnings  was  approximately  $3.9  million,  or $0.09 per diluted  share,
related to the decrease in the  Company's  valuation  allowance for its deferred
tax assets,  primarily  as it relates to its net  operating  loss  carryforwards
("NOL's").  The decrease in the Company's  valuation  allowance for its deferred
tax assets in the fourth  quarter of 2002 was  approximately  $3.5  million,  or
$0.08 per diluted share.  Excluding  these  valuation  allowance  benefits,  the
Company's net income  increased in the fourth  quarter of 2003 by  approximately
$437 thousand or 33.4 percent, as compared to the fourth quarter of 2002.




For the year ended December 31, 2003,  the Company's net revenues  reached $98.7
million,  as compared to net  revenues of $86.7  million in 2002, a 13.9 percent
increase.  Net product sales for 2003  increased by  approximately  15.8 percent
over 2002. Net income and earnings per diluted share for 2003 were $16.0 million
or $0.37,  respectively,  versus $8.4 million or $0.20,  respectively,  in 2002.
Included  in  earnings  for 2003 is  approximately  $8.8  million,  or $0.20 per
diluted share,  related to the decrease in the Company's valuation allowance for
its deferred tax assets and a gain of approximately $982 thousand,  or $0.02 per
diluted share,  from the sale of certain of the Company's  non-strategic  safety
products  during  the third  quarter  of 2003.  The  decrease  in the  Company's
valuation  allowance for its deferred tax assets in 2002 was approximately  $3.5
million,  or $0.08  per  diluted  share.  Excluding  these  valuation  allowance
benefits  and the gain  from  the sale of  non-strategic  safety  products,  the
Company's  earnings  in 2003  increased  by more  than 25  percent  to $0.15 per
diluted share from $0.12 per diluted share in 2002.

Dan R. Lee, the Company's President and Chief Executive Officer,  commented, "We
achieved  solid revenue growth in 2003, and the fourth quarter of 2003 marks the
Company's twelfth consecutive  quarter of profitability.  Microtek has delivered
solid growth due to our efficient manufacturing processes,  proprietary products
and extensive distribution channels. In 2003, we exhibited growth in each of our
principal  product  lines,  except our safety product line which was impacted by
the sale of a portion  of that line in  September  2003,  and  across all of our
distribution  channels.  OEM revenues,  which fell behind 2002 levels during the
first quarter,  rebounded  during the fourth quarter with a 23 percent  increase
over the  fourth  quarter  of  2002.  For the full  year of 2003,  OEM  revenues
increased by more than eight percent over 2002. The Company's  domestic  branded
hospital sales  increased by 12 percent during the fourth quarter of 2003 and by
11  percent  for  the  full  year.   Not  included  in  these  growth  rates  is
approximately  $1.1  million  in  revenues  from the  acquisition  of  Plasco on
November 1, 2003.  Together,  the growth in Microtek  OEM and  domestic  branded
hospital  revenues and revenues  from the Plasco  acquisition  bring  Microtek's
domestic  revenues  in  2003  to  approximately  $80  million,  an  increase  of
approximately  12 percent over 2002.  International  revenues also  demonstrated
double-digit  revenue  growth in the fourth  quarter and full year periods of 15
percent and 13 percent,  respectively.  Net product  sales of the  Company's OTI
division  were $1.2  million in the fourth  quarter of 2003 and $5.5 million for
the full year,  increases of 18.6  percent and 193.1  percent over the same 2002
periods."

Mr. Lee continued,  "In addition to strong revenue growth,  we also  experienced
improved  gross margins and  operating  margins  during 2003.  This is a notable
achievement  considering that we made planned investments in sales and marketing
during the year to promote our brand,  strengthen our distribution  channels and
improve our market position for the long-term."

For the fourth quarter of 2003, the Company's  gross profit margin  increased to
40.9 percent,  as compared to 38.3 percent in the fourth quarter of 2002.  Gross
profit margins for the full year of 2003 of 39.7 percent increased slightly from
39.4 percent in 2002.  The fourth  quarter and full year of 2002  benefited from
licensing revenues of $357 thousand and $1.4 million, respectively, which had no
associated costs.  Excluding  licensing revenues in the 2002 periods,  the gross
profit  margin  improvement  in the  fourth  quarter  and full  year of 2003 was
approximately  3.6 percentage  points and 1.4 percentage  points,  respectively.
These  improvements  are  attributable  to the effect of  leveraging  higher net
revenues  on our  existing  manufacturing  infrastructures  and  efficiency  and
utilization improvements realized in 2003.

Operating  expenses for the fourth  quarter of 2003 were $9.0  million,  or 34.0
percent of net product  sales,  as compared to $7.1 million,  or 32.6 percent of
net  product  sales in the fourth  quarter  of 2002.  For the full year of 2003,
operating expenses were $32.6 million,  or 33.1 percent of net product sales, as
compared to $28.5 million,  or 33.5 percent of net product  sales,  in 2002. The
increases in the absolute dollar amount of operating  expenses in fourth quarter
and full year of 2003 resulted from higher selling,  general and  administrative
expenses ("SG&A expenses"), primarily due to the Company's additional investment
in branded  sales and  marketing  and  higher  distribution  and other  variable



selling  costs.  SG&A  expenses were $8.7 million or 32.8 percent of net product
sales in the fourth quarter of 2003, compared to $6.8 million or 31.4 percent of
net  product  sales for the fourth  quarter of 2002.  For the full year of 2003,
SG&A expenses were $31.3 million,  or 31.7 percent of net product sales,  versus
$27.3 million, or 32.1 percent of net product sales in 2002.

The Company's  balance sheet remains strong with cash and  investments  totaling
$9.5 million at December 31, 2003, and a strong  current ratio  (current  assets
divided by current  liabilities) of 5.5 to 1. The Company's borrowings under its
revolving  credit  facility  amounted to $7.2 million and  additional  available
borrowings totaled approximately $7.9 million at December 31, 2003.

During the quarter,  the Company repurchased a total of 19 thousand shares under
its current share repurchase authorization bringing the total shares repurchased
in 2003  to 274  thousand  shares  at an  average  price  of  $2.72  per  share.
Approximately  1.3 million shares have been  repurchased  since the inception of
the program.  The Company's  current  share  repurchase  program,  as amended in
December 2003,  provides for the repurchase of approximately 658 thousand shares
of additional stock and extends through December 31, 2004.

Mr.  Lee  stated,  "Our  results  for 2003  are  generally  consistent  with our
expectations, except for the non-cash increase in the income tax benefit related
to a larger than  anticipated  decrease  in the  valuation  allowance  for NOL's
during  the fourth  quarter.  At  December  31,  2003,  we  assessed  the future
realizability of our Federal NOL's,  considering among other things management's
forecast of taxable  income in future  periods  during  which those NOL's may be
utilized.  In accordance with generally accepted accounting principles and based
on currently  available  information,  the  Company's  valuation  allowance  was
adjusted to reflect  management's  best estimate of the tax benefit that will be
realized from the  utilization  of these NOL's prior to their  expiration.  This
resulted in a decrease in the valuation allowance of approximately $8.8 million,
or $0.20 per diluted  share.  We had previously  estimated that this  adjustment
would be approximately  $0.15 per diluted share.  This increase  resulted from a
combination  of an increase in our actual 2003  taxable  income over our earlier
expectations  and  increases in  forecasted  utilization  of the  Company's  tax
benefits.  Going forward,  we will evaluate the  reasonableness of the remaining
valuation  allowance on our deferred tax assets and will make adjustments to the
valuation allowance as circumstances indicate."

Mr. Lee continued, "Excluding the effect of any possible future acquisitions, we
believe  that our revenues for 2004 will be in the range of $115 million to $120
million,  and we believe  income from  operations  in 2004 will increase by more
than 30 percent over 2003.  Additionally,  we believe that our earnings for 2004
will be in the  range of  $0.19  to $0.22  per  diluted  share.  Our  forecasted
earnings  exclude  any  non-cash  benefits  which may be  recorded  in 2004 from
decreases  in  the  Company's  valuation  allowance  for  deferred  tax  assets.
Decreases in the  valuation  allowance are recorded as a deferred tax benefit on
our statement of operations,  which  consequently  causes a non-cash increase in
our net income.  Because our valuation allowance at December 31, 2003 takes into
account our current risk-adjusted  forecast of our taxable income over more than
the next 10 years, we currently do not expect to record any material  changes to
our valuation allowance in 2004 and,  consequently,  do not currently expect any
material  change in our  forecasted  2004 earnings as a result of changes in our
valuation  allowance.  Changes  in  this  valuation  allowance  are  subject  to
judgments  about unknown  future  events,  so future  developments  could have a
significant effect on the amount of our valuation allowance and, consequently, a
non-cash effect on our net income."

Mr. Lee concluded,  "Our forecasted earnings of $0.19 to $0.22 per diluted share
for 2004  compare  favorably  to earnings  of $0.15 per  diluted  share in 2003,
excluding the $8.8 million in valuation  allowance benefits and one-time gain of
$982 thousand.  We will continue to focus on organic growth in our product lines
through innovation and expanding our distribution  channels, and we will seek to
maintain our strong  financial  position with direct focus on our favorable cash



position, modest debt and sound working capital.  Additionally, we will continue
to seek  strategic  acquisitions  which  complement  our  goal of being a market
leader in the design,  manufacture  and marketing of a wide range of innovative,
high-quality products for infection and fluid control and for the enhancement of
patient and healthcare professionals' safety."

CONFERENCE  CALL:  The Company  invites its  shareholders  and other  interested
parties  to join its  conference  call which  will be  conducted  by Dan R. Lee,
President  and Chief  Executive  Officer,  and  Jerry  Wilson,  Chief  Financial
Officer,  at 4:30 p.m.  Eastern Time on February 24, 2004.  This conference call
will be accessible to the public by calling  1-877-407-9210  (U.S.),  Reference:
Microtek Medical. International callers dial 1-201-689-8049. Callers should dial
in approximately 10 minutes before the call begins.

To access  the live  broadcast  of the call over the  Internet,  go to  Investor
Relations page at www.MicrotekMed.com.

A conference  call replay will be available  through 11:59 p.m.  Eastern Time on
March  1,  2004  and  can  be  accessed  by  calling  1-877-660-6853  (U.S.)  or
1-201-612-7415  (international);  for both  reference  conference  call  account
#1628, Conference ID #93422.

ACTUAL RESULTS COULD DIFFER FROM FORWARD-LOOKING  STATEMENTS: This Press Release
contains forward-looking  statements made pursuant to the safe harbor provisions
of the  Private  Securities  Litigation  Reform  Act of  1995.  Such  statements
include, but are not limited to, the Company's  forecasted revenues,  forecasted
increase in income from operations and forecasted earnings per diluted share for
2004,  the  Company's  ability to  continue  to focus on  organic  growth in its
product lines through  innovation and expanding its distribution  channels,  the
Company's ability to maintain its strong financial position with direct focus on
its favorable  cash  position,  modest debt and sound working  capital,  and the
Company's  ability to consummate  strategic  acquisitions  that  complement  the
Company's goal of being a market leader in the design, manufacture and marketing
of a wide range of  innovative,  high-quality  products for  infection and fluid
control and for the engagement of patient and healthcare  professionals' safety.
Such statements are subject to certain factors, risks and uncertainties that may
cause actual results, events and performance to differ from those referred to in
such statements.  These risks include,  without limitation,  those identified in
Risk  Factors  in the  Company's  Annual  Report on Form 10-K for the year ended
December 31, 2002,  including,  without limitation,  the risks described in Risk
Factors under the captions "-History of Net Losses",  "-Reliance upon Microtek",
"-Competition", "-Product Liability", "-Stock Price Volatility", "-Dependence on
Key  Personnel",  "-Anti-takeover  Provisions",  "-Low  Barriers  to  Entry  for
Competitive  Products",  "-Potential  Erosion  of Profit  Margins",  "-Risks  of
Completing  Acquisitions",  "-Small Sales and Marketing Force",  "-Reliance upon
Distributors", "-Microtek Regulatory Risks", "-Risks of Obsolescence", "-Reduced
OREX Market Potential",  " OREX  Commercialization  Risks", "-OREX Manufacturing
and Supply  Risks",  "-Risks  Affecting  Protection of  Technology",  "-Risks of
Technological  Obsolescence" and "-OTI Regulatory Risks". We do not undertake to
update our forward-looking statements to reflect future events or circumstances.

ABOUT  MICROTEK:  The  Company,  a market  leader  in the  healthcare  industry,
develops,  manufactures  and sells  infection  control  products,  fluid control
products and safety products to healthcare professionals for use in environments
such as operating rooms and outpatient surgical centers.



FOR MORE INFORMATION, PLEASE CALL (800) 476-5973
Dan R. Lee, President & CEO
Jerry Wilson, CFO
John Mills, Investor Relations
InvestorRelations@MicrotekMed.com

                                -TABLES FOLLOW -










                                                    MICROTEK MEDICAL HOLDINGS, INC.
                                                    Unaudited Financial Highlights


                                                                                                        
                                                              THREE MONTHS ENDED                       TWELVE MONTHS ENDED
(in thousands, except per share data)                             DECEMBER 31                              DECEMBER 31
                                                     --------------------------------------    -------------------------------------
                                                           2003                 2002                 2003                2002
                                                     -----------------    -----------------    -----------------    ----------------
     Net product sales                                $        26,462      $        21,780      $        98,664      $       85,228
     Licensing revenues                                             -                  357                    -               1,427
                                                     -----------------    -----------------    -----------------    ----------------
                  Net revenues                                 26,462               22,137               98,664              86,655
                  Gross profit                                 10,828                8,472               39,216              34,101
     Operating expenses:
        Selling, general and administrative                     8,670                6,830               31,261              27,326
        Research and development                                  227                  164                  940                 736
        Amortization of intangibles                               113                  114                  440                 456
                                                     -----------------    -----------------    -----------------    ----------------
           Total operating expenses                             9,010                7,108               32,641              28,518
                                                     -----------------    -----------------    -----------------    ----------------
                    Income from operations                      1,818                1,364                6,575               5,583
     Interest expense, net                                        (45)                 (21)                (179)               (429)
     Gain on sale of product line                                   -                    -                  982                   -
     Other income, net                                             56                   15                  135                  89
                                                     -----------------    -----------------    -----------------    ----------------
                    Income before income taxes                  1,829                1,358                7,513               5,243
     Current tax expense - state and foreign                      (81)                 (47)                (301)               (332)
     Deferred tax benefit                                       3,930                3,503                8,811               3,503
                                                     -----------------    -----------------    -----------------    ----------------
                    Net income                        $         5,678      $         4,814      $        16,023      $        8,414
                                                     =================    =================    =================    ================
     Net income per share:
        Basic                                         $          0.13      $          0.11      $          0.38      $         0.20
                                                     =================    =================    =================    ================
        Diluted                                       $          0.13      $          0.11      $          0.37      $         0.20
                                                     =================    =================    =================    ================
     Weighted average shares outstanding:
         Basic                                                 42,490               42,024               42,206              42,125
         Diluted                                               44,016               42,398               43,251              42,789

     BALANCE SHEET DATA:                               DECEMBER 31          DECEMBER 31
                                                           2003                 2002
                                                     -----------------    -----------------
     Cash and cash equivalents                        $         9,462      $         9,823
     Other current assets                                      54,749               41,757
        Total current assets                                   64,211               51,580
        Total assets                                          118,299               96,696
                                                     =================    =================
     Current liabilities                              $        11,691      $         8,630
     Long term debt                                             8,056                7,136
     Other liabilities                                          2,008                2,044
                                                     -----------------    -----------------
        Total liabilities                                      21,755               17,810
     Shareholders' equity                                      96,544               78,886
                                                     -----------------    -----------------
        Total liabilities and shareholders' equity    $       118,299      $        96,696
                                                     =================    =================