EXHIBIT 99.1


                                                                  [COMPANY LOGO]
FOR IMMEDIATE RELEASE

          MICROTEK MEDICAL HOLDINGS REPORTS THIRD QUARTER 2004 RESULTS

      THIRD QUARTER 2004 NET REVENUES INCREASE 40% OVER PRIOR YEAR QUARTER
    CASH FLOWS FROM OPERATING ACTIVITIES FOR FIRST NINE MONTHS INCREASE OVER
              125% TO $9.6 MILLION AS COMPARED TO THE 2003 PERIOD

COLUMBUS, MS, November 3, 2004 - Microtek Medical Holdings, Inc. (Nasdaq: MTMD),
a leading manufacturer and marketer of infection control products, fluid control
products  and  safety  products  to  healthcare  professionals,  today  reported
financial  results for the third  quarter and nine months  ended  September  30,
2004. Highlights from the third quarter and nine month period of 2004 include:

o    Net revenues increased 39.6 percent over the third quarter of 2003 and 29.4
     percent over the first nine months of 2003;
o    Organic healthcare  revenues grew 11.8 percent in third quarter of 2004 and
     12.4 percent in the first nine months of 2004;
o    Net income for the third  quarter  and first nine  months of 2004 was $0.05
     per diluted share and $0.13 per diluted share, respectively;
o    Cash flows from operating activities for the first nine months of 2004 were
     $9.6 million, up from $4.2 million for the 2003 period;
o    Completed  license  agreement for OREX materials and processing  technology
     for nuclear applications,  including sale of certain property and equipment
     for one-time gain of $210 thousand.

THIRD QUARTER AND NINE MONTH RESULTS

Net revenues for the third  quarter of 2004 were $34.0  million,  an increase of
$9.7 million or 39.6 percent over the third quarter of 2003.  Net income for the
2004 quarter was $2.2 million,  or $0.05 per diluted share,  as compared to $4.9
million,  or $0.11 per diluted share in the third  quarter of 2003.  Included in
the third quarter 2003 earnings was an income tax benefit of approximately  $2.4
million  related to the decrease in the  Company's  valuation  allowance for its
deferred tax assets,  primarily its net operating loss carryforwards  ("NOL's"),
with no  corresponding  benefit in the third  quarter of 2004.  Also included in
third quarter 2003 and 2004 earnings were gains  resulting from  dispositions of
property  and  equipment  of $982  thousand  and  $215  thousand,  respectively.
Excluding the non-cash deferred tax benefit in the third quarter of 2003 and the
gains on  dispositions  of property and equipment in the third  quarters of 2003
and 2004,  the  Company's  net  income  in the 2004  quarter  increased  by $376
thousand, or 24 percent, over the 2003 quarter.

For the nine months ended  September 30, 2004,  the Company earned $5.6 million,
or $0.13 per diluted  share,  on revenues of $93.4  million,  as compared to net
income of $10.3  million,  or $0.24 per  diluted  share,  on  revenues  of $72.2
million  for the same period in 2003.  Excluding  non-cash  deferred  income tax
benefits  of $4.9  million  recorded  in the first  nine  months of 2003 and the
aforementioned  gains on dispositions  of property and equipment,  the Company's
net income for the first nine months of 2004 increased by $903  thousand,  or 20
percent, over the first nine months of 2003.

Income from  operations  for the third quarter and first nine months of 2004 was
$2.5 million and $6.3 million,  respectively, as compared to $2.6 million in the
third  quarter  of 2003 and $5.7  million  for the  first  nine  months of 2003.


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Excluding gains on dispositions of property and equipment,  the Company's income
from operations for the third quarter and first nine months of 2004 increased by
$649  thousand,  or 40.4 percent,  and $1.3 million,  or 27.2 percent,  over the
third quarter and first nine months of 2003, respectively.

Dan R. Lee, the Company's President and Chief Executive Officer,  commented "Our
revenue   accomplishments  this  quarter  exhibit  the  substantial  effort  and
investment we have made to continuously  improve our revenue performance and, in
particular,  to promote  the  organic  development  of our  existing  healthcare
product lines. Additionally, our recent healthcare acquisitions have contributed
significantly  to  our  overall  growth.  Revenues  related  to  our  healthcare
operations, excluding acquisitions, were $25.7 million and $76.3 million for the
third quarter and first nine months of 2004, respectively, and represent organic
growth rates of 11.8 percent and 12.4 percent over the respective  2003 periods.
Combined  with  year-to-date  revenues of $7.1 million from the Plasco  division
which  was  acquired  in  November  2003 and  $4.3  million  related  to the IMP
acquisition which was completed on May 28, 2004, our healthcare revenues through
September  2004 reached $87.7  million,  a 29.4 percent  increase over the first
nine months of 2003. Equally as impressive, our healthcare revenues through nine
months in 2004 already  exceed 94 percent of our total  healthcare  revenues for
the full year of 2003. We are very proud of these accomplishments."

Mr. Lee continued,  "The balance of our revenues for the third quarter and first
nine months of 2004  totaled $2.7 million and $5.7  million,  respectively,  and
were generated by our OREX Technologies  International ("OTI") division. Of this
amount,  approximately  $1.2 million related to the sale of certain raw material
inventories  used in the  manufacture  of finished goods for sale to the nuclear
industry. This raw material sale was completed as part of the recently announced
licensing  of our OREX  nuclear  technology  to Eastern  Technologies,  Inc.  in
September 2004 (the "ETI  transaction").  The ETI transaction is the culmination
of three years of internal  evaluation of the OREX nuclear  business and various
alternatives for this business once sustainable  commercialization was achieved.
We  believe  that our  agreements  with ETI  provide  an  advantageous  means of
separating  that business from our healthcare  operations  while  maximizing the
value  of  the  OREX  technology  to our  shareholders.  With  this  transaction
complete,  we are now able to focus  all of our  efforts  and  resources  on our
strategic healthcare initiatives."

During the 2004 quarter, the Company's domestic healthcare  revenues,  including
Plasco  division  revenues of $2.2  million,  grew 20 percent to $23.7  million.
Contributing to this increase,  the Company's domestic branded hospital revenues
grew 29.0 percent over the 2003 quarter as a result of revenues  from the Plasco
division and growth across  substantially all of the Company's principal product
lines,  most notably CleanOp,  a consistent  contributor to revenue growth,  and
Venodyne,  a line of compression  pumps and sleeves  designed to treat deep vein
thrombosis.  Additionally,  third  quarter  2004  OEM  revenues  increased  $800
thousand  over the 2003  quarter to $9.5  million  primarily  as a result of the
Plasco  acquisition.  The  Company's  international  revenues for 2004  quarter,
including  $3.4  million  related  to  the  IMP  acquisition,   demonstrated  an
impressive 133 percent increase. Excluding IMP revenues,  international revenues
for the third  quarter  of 2004  increased  by  approximately  30  percent.  Net
revenues of the Company's OTI division were $2.7 million in the third quarter of
2004, an increase of $1.3 million over the same quarter last year. Approximately
$555 thousand of this increase was directly  related to increased  product sales
to the nuclear industry.  The remaining  increase of approximately $777 thousand
related to increased  sales of raw materials used in the  manufacture of nuclear
finished goods.  In conjunction  with the ETI transaction in September 2004, OTI
sold approximately  $1.2 million of these raw material  inventories to a related
party.

Mr. Lee stated,  "Our gross profit  margins for the third quarter and first nine
months of 2004 were 38.2 percent and 38.9 percent,  respectively, as compared to
40.2  percent and 39.3  percent  for the third  quarter and first nine months of
2003,  respectively.  The decreases noted in the 2004 periods  resulted from our
product  mix in the third  quarter  and first nine months of 2004 as compared to
the same prior year  periods  and the  slightly  dilutive  nature of  Microtek's
international  business  (excluding  IMP),  Microtek's  CleanOP product line and
OTI's  revenues in relation to other of Microtek's  branded  hospital  revenues.
With the  completion  of the ETI  transaction  and through a number of sales and
marketing and other manufacturing  initiatives currently underway, we believe we
will see an improvement in our consolidated gross margins going forward."

Selling,  general and administrative  ("SG&A") expenses for the third quarter of
2004 were $10.3  million,  or 30.2 percent of net revenues,  as compared to $7.8
million,  or 32.2 percent of net revenues in the third quarter of 2003.  For the


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first nine months of 2004, SG&A expenses were $29.0 million,  or 31.0 percent of
net revenues,  versus $22.6  million,  or 31.3 percent,  of net revenues for the
first nine months of 2003.  The net  increase in the absolute  dollar  amount of
SG&A  expenses in the third quarter of 2004 resulted  primarily  from  operating
expenses  related to the recently  acquired  Plasco and IMP  businesses,  higher
distribution  and  other  variable  selling  costs  associated  with  increasing
revenues,  and other planned  investments  in selling and  marketing  during the
quarter.  The  improvements  in SG&A expenses as a percentage of net revenues in
the 2004 quarter and year-to-date  periods  demonstrate the leveraging effect of
increasing revenues.

At September 30, 2004, the Company's cash and  investments  totaled $8.9 million
and its borrowings  under its credit facility were $6.9 million,  as compared to
cash and  investments  of $9.5 million and credit  facility  borrowings  of $7.2
million at December 31, 2003.  The  Company's  strong cash flows from  operating
activities  through the first nine months of 2004 of more than $9.6 million have
enabled the financing of the IMP  acquisition  and the  Company's  other capital
needs with a relatively  insignificant change in the Company's net cash position
(which is defined as cash and  investments  less the Company's  credit  facility
borrowings).

Mr. Lee concluded,  "We are encouraged by our accomplishments  through the first
three  quarters of 2004. We believe that the sales and marketing  infrastructure
that we  have  been  building  over  the  last 18  months  is now  substantially
complete.  During the third quarter of 2004, we began to realize our leverage on
that SG&A  infrastructure  and are looking for  additional  improvements  in the
future.  We  believe  the  investment  we have made in our  sales and  marketing
platform  over  the past  year and a half  will  provide  significant  long-term
benefits.  We are committed to continuing  our efforts to grow our operating and
net  income  margins  by  improving  gross  margins  and  controlling  operating
expenditures.  We currently  believe that our revenues for the fourth quarter of
2004 will be  approximately  $30  million,  bringing  our full year 2004 revenue
forecast  to  approximately  $123  million.  On these  revenues,  we expect  our
earnings to be in the range of $0.05 and $0.06 per diluted  share for the fourth
quarter of 2004 and therefore,  in the range of $0.18 to $0.19 per diluted share
for the full year of 2004."


CONFERENCE  CALL:  The Company  invites its  shareholders  and other  interested
parties  to join its  conference  call which  will be  conducted  by Dan R. Lee,
President  and Chief  Executive  Officer,  and  Jerry  Wilson,  Chief  Financial
Officer,  at 4:30  p.m.  Eastern  Time on  Wednesday,  November  3,  2004.  This
conference  call will be  accessible  to the  public by  calling  1-877-407-9210
(U.S.), Reference: Microtek Medical.  International callers dial 1-201-689-8049.
Callers  should dial in  approximately  10 minutes  before the call  begins.  To
access  the  live  broadcast  of the  call  over the  Internet,  go to  Investor
Relations page at www.MicrotekMed.com.

A conference  call replay will be available  through 11:59 p.m.  Eastern Time on
November  10,  2004 and can be  accessed  by  calling  1-877-660-6853  (U.S.) or
1-201-612-7415  (international);  for both  reference  conference  call  account
#1628, Conference ID #120466.

ACTUAL RESULTS COULD DIFFER FROM FORWARD-LOOKING  STATEMENTS: This Press Release
contains forward-looking  statements made pursuant to the safe harbor provisions
of the  Private  Securities  Litigation  Reform  Act of  1995.  Such  statements
include,  but are  not  limited  to,  the  Company's  expectation  that  the ETI
transaction  and a  number  of  sales  and  marketing  and  other  manufacturing
initiatives  currently  underway  will  result in  improved  consolidated  gross
margins going forward,  the Company's  belief that the building of its sales and
marketing  infrastructure has substantially been completed, the Company's belief
that  leverage of its sales and  marketing  infrastructure  will  improve in the
future,  the Company's  belief that  investments made in its sales and marketing
platform will provide significant  long-term benefits,  the Company's ability to
grow its  operating  and net  income  margins by  improving  gross  margins  and
controlling  operating  expenditures,  and the Company's forecasted revenues and
forecasted  earnings per diluted  share for the fourth  quarter and full year of
2004. Such statements are subject to certain  factors,  risks and  uncertainties
that may cause  actual  results,  events and  performance  to differ  from those
referred to in such statements.  These risks include, without limitation,  those
identified in Risk Factors in the  Company's  Annual Report on Form 10-K for the
year ended December 31, 2003, including, without limitation, the risks described
in Risk Factors under the captions  "-Reliance upon Microtek",  "-History of Net


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Losses",  "-Competition",   "-Product  Liability",  "-Stock  Price  Volatility",
"-Dependence on Key Personnel",  "-Anti-takeover Provisions",  "-Low Barriers to
Entry for Competitive Products", "-Potential Erosion of Profit Margins", "-Risks
of Completing Acquisitions",  "-Risks of Successfully Integrating Acquisitions",
"-Small Sales and Marketing Force",  "-Reliance upon  Distributors",  "-Reliance
Upon Large Customers",  "-Microtek Regulatory Risks",  "-Risks of Obsolescence",
"-Reduced  OREX  Market  Potential",  " OREX  Commercialization  Risks",  "-OREX
Manufacturing and Supply Risks",  "-Risks  Affecting  Protection of Technology",
"-Risks of Technological  Obsolescence"  and "-OTI Regulatory  Risks". We do not
undertake to update our  forward-looking  statements to reflect future events or
circumstances.

ABOUT  MICROTEK:  The  Company,  a market  leader  in the  healthcare  industry,
develops,  manufactures  and sells  infection  control  products,  fluid control
products and safety products to healthcare professionals for use in environments
such as operating rooms and outpatient surgical centers.

FOR MORE INFORMATION, PLEASE CALL (800) 476-5973
Dan R. Lee, President & CEO
Jerry Wilson, CFO
John Mills, Investor Relations
InvestorRelations@MicrotekMed.com


                                -TABLES FOLLOW -



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                                                    MICROTEK MEDICAL HOLDINGS, INC.
                                                     UNAUDITED FINANCIAL HIGHLIGHTS
                                                                                                       
(in thousands, except for per share data)                        THREE MONTHS ENDED                     NINE MONTHS ENDED
                                                                    SEPTEMBER 30                           SEPTEMBER 30
                                                        --------------------------------------    -------------------------------
                                                               2004                 2003                2004             2003
                                                        ------------------    ----------------    -------------    --------------
Net revenues                                              $        33,984       $      24,342       $   93,438       $    72,202
Gross profit                                                       12,972               9,787           36,304            28,388
Operating expenses:
      Selling, general and administrative                          10,253               7,843           28,978            22,591
      Research and development                                        304                 235              812               713
      Amortization of intangibles                                     159                 102              465               327
                                                        ------------------    ----------------    -------------    --------------
         Total operating expenses                                  10,716               8,180           30,255            23,631
                                                        ------------------    ----------------    -------------    --------------
Gain on dispositions                                                  215                 982              215               982
                                                        ------------------    ----------------    -------------    --------------

Income from operations                                              2,471               2,589            6,264             5,739
Interest expense, net                                                 (84)                (40)            (194)             (134)
Other income, net                                                      84                  56              108                79
                                                        ------------------    ----------------    -------------    --------------
      Income before income taxes                                    2,471               2,605            6,178             5,684
Income taxes:
    Current tax expense - state and foreign                          (287)                (30)            (578)             (220)
    Deferred tax benefit                                                -               2,366                -             4,881
                                                        ------------------    ----------------    -------------    --------------
           Total income tax (expense) benefit                        (287)              2,336             (578)            4,661
                                                        ------------------    ----------------    -------------    --------------

      Net income                                          $         2,184       $       4,941       $    5,600       $    10,345
                                                        ==================    ================    =============    ==============
Net income per share - basic                              $          0.05       $        0.12       $     0.13       $      0.25
                                                        ==================    ================    =============    ==============
Net income per share - diluted                            $          0.05       $        0.11       $     0.13       $      0.24
                                                        ==================    ================    =============    ==============

Weighted average shares outstanding - basic                        43,102              42,154           42,951            42,111
                                                        ==================    ================    =============    ==============
Weighted average shares outstanding - diluted                      44,409              43,451           44,506            43,010
                                                        ==================    ================    =============    ==============

                                                           SEPTEMBER 30,         DECEMBER 31,
BALANCE SHEET DATA:                                             2004                  2003
                                                        ------------------    ----------------
Cash and cash equivalents                                 $         8,902       $       9,462
Other current assets                                               55,982              54,749
         Total current assets                                      64,884              64,211
         Total assets                                             127,714             118,299
                                                        ==================    ================
Current liabilities                                       $        14,804       $      11,691
Long term debt                                                      7,410               8,056
Other liabilities                                                   1,757               2,008
                                                        ------------------    ----------------
         Total liabilities                                         23,971              21,755
Shareholders' equity                                              103,743              96,544
                                                        ------------------    ----------------
         Total liabilities and shareholders' equity       $       127,714       $     118,299
                                                        ==================    ================




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