EXHIBIT 31.1

                                 CERTIFICATIONS

I, Dan R. Lee, certify that:

1.   I have  reviewed  this  annual  report  on Form  10-K of  Microtek  Medical
     Holdings, Inc.;

2.   Based on my knowledge, this report does not contain any untrue statement of
     a material  fact or omit to state a  material  fact  necessary  to make the
     statements made, in light of the circumstances  under which such statements
     were made,  not  misleading  with  respect  to the  period  covered by this
     report;

4.   The  registrant's  other  certifying  officer(s) and I are  responsible for
     establishing and maintaining disclosure controls and procedures (as defined
     in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the registrant and have:

     a)   Designed  such  disclosure  controls  and  procedures,  or caused such
          disclosure   control  and   procedures   to  be  designed   under  our
          supervision,  to ensure  that  material  information  relating  to the
          registrant,  including its consolidated subsidiaries, is made known to
          us by others within those entities,  particularly during the period in
          which this report is being prepared;

     c)   Evaluated the  effectiveness of the registrant's  disclosure  controls
          and procedures and presented in this report our conclusions  about the
          effectiveness of the disclosure controls and procedures, as of the end
          of the period covered by this report based on such evaluation; and

     d)   Disclosed  in this  report  any  change in the  registrant's  internal
          control over financial reporting that occurred during the registrant's
          most recent fiscal quarter (the registrant's  fourth fiscal quarter in
          the case of an annual  report)  of the  fiscal  year  covered  by this
          annual report that has materially affected, or is reasonably likely to
          materially  affect,  the registrant's  internal control over financial
          reporting; and

5.   The registrant's other certifying officer(s) and I have disclosed, based on
     our evaluation of internal control over financial  reporting  conducted for
     purposes of this annual report, to the registrant's  auditors and the audit
     committee of the registrant's board of directors (or persons performing the
     equivalent functions):

     a)   All significant  deficiencies and material weaknesses in the design or
          operation  of internal  control  over  financial  reporting  which are
          reasonably  likely to  adversely  affect the  registrant's  ability to
          record, process, summarize and report financial information; and

     b)   Any fraud, whether or not material,  that involves management or other
          employees who have a  significant  role in the  registrant's  internal
          control over financial reporting.


Date: March 4, 2005                     /s/ Dan R. Lee
                                        ----------------------------------------
                                        Dan R. Lee
                                        Chairman, President and Chief Executive
                                        Officer