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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

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                                    FORM 8-K
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                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

         DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED): JUNE 30, 2005

                             -----------------------

                         MICROTEK MEDICAL HOLDINGS, INC.
             (Exact name of registrant as specified in its charter)
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                GEORGIA                                 0-24866                              58-1746149
                -------                                 -------                              ----------
     (State or Other Jurisdiction              (Commission File Number)                     (IRS Employer
           of Incorporation)                                                             Identification No.)


          13000 DEERFIELD PARKWAY, SUITE 300, ALPHARETTA, GEORGIA 30004
               (Address of principal executive office) (zip code)

       REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: (678) 896-4400


          (Former name or former address, if changed since last report)

                            -------------------------

     Check the  appropriate  box below if the Form 8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

|_|  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

|_|  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))

|_|  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))

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ITEM 1.01  ENTRY INTO A MATERIAL DEFINITIVE AGREEMENT.

     On June 30, 2005,  the Company  amended its credit  agreement  (the "Credit
     Agreement")  with  JPMorgan  Chase Bank to extend the maturity  date of the
     related  revolving  credit  facility  from June 30, 2006 to June 30,  2008,
     modify  the  interest  margin  pursuant  to  which  the  interest  rate  on
     borrowings is  determined,  and modify  various of the financial  covenants
     contained in the Credit Agreement.

ITEM 9.01  FINANCIAL STATEMENTS AND EXHIBITS.

     (a) Financial Statements.

         N/A

     (b) Pro Forma Financial Information.

         N/A

     (c) Exhibits.

         Exhibit
         Number     Description
         -------    -----------
          10.1      Ninth Amendment  Agreement dated as of June 30, 2005, to the
                    Amended and Restated Credit  Agreement,  dated as of May 14,
                    2001





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                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Company  has  duly  caused  this  report  to be  signed  on  its  behalf  by the
undersigned hereunto duly authorized.

                                       MICROTEK MEDICAL HOLDINGS, INC.



Date:  June 30, 2005                   By:  /s/ Dan R. Lee
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                                            Dan R. Lee, Chairman, President and
                                            Chief Executive Officer




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                                  EXHIBIT INDEX


Exhibit
Number    Description
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10.1      Ninth  Amendment  Agreement  dated as of June 30, 2005, to the Amended
          and Restated Credit Agreement, dated as of May 14, 2001




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