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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                        --------------------------------

                                    FORM 8-K
                        --------------------------------


                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

         DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED): JULY 8, 2005

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                         MICROTEK MEDICAL HOLDINGS, INC.
                         -------------------------------
             (Exact name of registrant as specified in its charter)
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                GEORGIA                                 0-24866                              58-1746149
                -------                                 -------                              ----------
     (State or Other Jurisdiction              (Commission File Number)                     (IRS Employer
           of Incorporation)                                                             Identification No.)


          13000 DEERFIELD PARKWAY, SUITE 300, ALPHARETTA, GEORGIA 30004
               (Address of principal executive office) (zip code)

       REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: (678) 896-4400


                  --------------------------------------------
          (Former name or former address, if changed since last report)

                            -------------------------

     Check the  appropriate  box below if the Form 8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

|_|  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

|_|  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))

|_|  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))

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                                                                -4-
ITEM 2.02  RESULTS OF OPERATIONS AND FINANCIAL CONDITION.

     On July 8, 2005,  Microtek Medical Holdings,  Inc. (the "Company") issued a
     press release announcing its anticipated net revenues for the quarter ended
     June 30,  2005.  This press  release is  attached  as Exhibit  99.1 to this
     report and is incorporated herein by reference.


ITEM 9.01  FINANCIAL STATEMENTS AND EXHIBITS.

     (a) Financial Statements.

         N/A

     (b) Pro Forma Financial Information.

         N/A

     (c) Exhibits.

         Exhibit Number    Description

             99.1          Press  release  dated July 8,  2005,  announcing  the
                           Company's  anticipated net  revenues for  the quarter
                           ended June 30, 2005



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                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Company  has  duly  caused  this  report  to be  signed  on  its  behalf  by the
undersigned hereunto duly authorized.

                                         MICROTEK MEDICAL HOLDINGS, INC.



Date:  July 8, 2005                      By: /s/ Dan R. Lee
                                             -----------------------------------
                                             Dan R. Lee, Chairman, President and
                                             Chief Executive Officer


                                         By: /s/ Roger G. Wilson
                                             -----------------------------------
                                             Roger G. Wilson, Chief Financial
                                             Officer


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                                  EXHIBIT INDEX



         Exhibit Number    Description

             99.1          Press  release  dated July 8,  2005,  announcing  the
                           Company's  anticipated net  revenues for  the quarter
                           ended June 30, 2005



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