EXHIBIT 99.1


                                                                  [COMPANY LOGO]

FOR IMMEDIATE RELEASE

              MICROTEK MEDICAL HOLDINGS EXPECTS SECOND QUARTER 2005
                     REVENUES OF APPROXIMATELY $34.5 MILLION

        SECOND QUARTER REVENUES EXPECTED TO INCREASE MORE THAN 14 PERCENT
                            OVER PRIOR YEAR QUARTER

            SCHEDULES QUARTERLY EARNINGS RELEASE AND CONFERENCE CALL

ALPHARETTA,  GA, July 8, 2005 - MICROTEK MEDICAL HOLDINGS,  INC. (NASDAQ:  MTMD)
announced  today that it expects to report net  revenues for the quarter and six
months ended June 30, 2005 of  approximately  $34.5  million and $68.2  million,
respectively.  The anticipated net revenues for the second quarter and first six
months of 2005  represent  increases  of  approximately  $4.3  million,  or 14.2
percent,  and  approximately  $8.7  million,  or 14.6  percent,  over the second
quarter and first six months of 2004, respectively.

The Company has not yet completed its accounting for the second quarter of 2005.
The Company's expectations about what it will report for revenues for the second
quarter and first six months of 2005 are  tentative  pending the  completion  of
such accounting.

CONFERENCE CALL:
The  Company's  results of  operations  for the quarter  ended June 30, 2005 are
scheduled to be released on Thursday,  August 4, 2005. A conference call will be
conducted by Dan R. Lee, President and CEO, and Jerry Wilson,  CFO, at 4:30 p.m.
Eastern Time on August 4, 2005,  and will be accessible to the public by calling
1-877-407-9210,   Reference:   Microtek  Medical.   International  callers  dial
1-201-689-8049.  Callers should dial in approximately 10 minutes before the call
begins.  To access the live broadcast of the call over the Internet,  log on to:
www.microtekmed.com

A conference  call replay will be available  through 11:59 p.m.  Eastern Time on
August 11, 2005 and can be accessed by calling 1-877-660-6853 or (international)
1-201-612-7415; for both reference conference call account #286, Conference ID #
160590.

ABOUT MICROTEK MEDICAL:
Microtek Medical is a leading  manufacturer  and supplier of innovative  product
solutions for patient care, occupational safety and management of infectious and
hazardous  waste  for  the  healthcare  industry.  Headquartered  near  Atlanta,
Georgia,  the Company  offers an  extensive  line of  infection  control,  fluid
control and safety  products,  such as disposable  equipment and patient drapes,
which are  marketed  to  healthcare  professionals  through  multiple  channels,
including direct sales, original equipment  manufacturers  ("OEM's") and private
label   arrangements.   Microtek   Medical's  goal  is  to  provide   healthcare
professionals  with innovative  product solutions that encompass a high-level of
patient care and prevention of cross infection in operating rooms and ambulatory
surgical centers worldwide. For further information, visit www.microtekmed.com.

I.For More Information, Please Call (800) 476-5973
Dan R. Lee, President & CEO
Roger G. (Jerry) Wilson, CFO
John Mills, Investor Relations
Investorrelations@microtekmed.com